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1,000+ results for "Survival"

How does the human brain switch between survival tasks?

Researchers found that patterns of neural activity in the hypothalamus predict performance in survival tasks, while associations with other brain regions were observed for hunting and escaping behaviors. The study provides new insights into how the human brain coordinates survival strategies.

SourcePLOS·JournalPLOS Biology·TypeComputational simulation/modeling·DateJun 27, 2024

ASCO: Combination therapy significantly improves outcomes for patients with metastatic colorectal cancer

A study by UCLA Health Jonsson Comprehensive Cancer Center researchers found that combining experimental immunotherapy drugs with chemotherapy significantly improves progression-free survival and overall survival for patients with metastatic colorectal cancer. The median progression-free survival was 6.2 months compared to 2.1 months f...

New treatment for a rare and aggressive cancer improves survival rates in breakthrough clinical trial

A new treatment combining a novel drug with traditional chemotherapy has been shown to increase the survival of patients with malignant mesothelioma, a rare and aggressive cancer. The ATOMIC-meso trial found that this treatment quadrupled the survival at 36 months compared to placebo-chemotherapy.

SourceQueen Mary University of London·JournalJAMA Oncology·TypeRandomized controlled/clinical trial·DateFeb 15, 2024

Study overturns conventional wisdom about wild turkey nesting survival

A new study has overturned conventional wisdom on wild turkey nesting survival, revealing that precipitation levels during nesting season are not related to reproductive success. The researchers found that temperatures above historical averages were associated with higher rates of daily nest survival during incubation.

SourceNorth Carolina State University·JournalJournal of Wildlife Management·TypeObservational study·DateDec 13, 2023

New approach to pancreatic cancer treatment expands therapeutic possibilities, shows promise for increased survival

Researchers have discovered a promising new treatment option for pancreatic cancer, using polyinosine-polycytidylic acid (pIC) delivered directly into tumor cells. The approach suppresses tumor growth, induces cancer cell death, and enhances survival in animal models with the most common form of pancreatic cancer.

SourceVirginia Commonwealth University·JournalJournal for ImmunoTherapy of Cancer·DateNov 10, 2023

Kaiser Permanente cancer survival rates higher

Researchers found higher 5-year survival rates among Kaiser Permanente patients compared to National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) estimates. Improved screening rates, cancer treatment pathways, and coordinated care may have contributed to these higher survival rates.

SourceKaiser Permanente·JournalThe Permanente Journal·DateSep 20, 2023

Screening newborns for "bubble-baby" disease saves lives

A new study shows that newborn screening for severe combined immunodeficiency disease (SCID) has significantly increased the survival rate of children after bone marrow transplantation from 73% to 87%. Children diagnosed at birth have a 92.5% survival rate without infection, while those diagnosed later have lower rates.

SourceUniversity of Montreal·JournalThe Lancet·TypeData/statistical analysis·DateJun 21, 2023

ASCO: Axi-cel significantly improves survival in patients with early relapsed or refractory large B-cell lymphoma

A Phase III trial found that axicabtagene ciloleucel (axi-cel) significantly improved overall survival and progression-free survival in patients with early relapsed or refractory large B-cell lymphoma, compared to standard therapy. The estimated four-year survival rate was 54.6% with axi-cel.

SourceUniversity of Texas M. D. Anderson Cancer Center·JournalNew England Journal of Medicine·DateJun 5, 2023

New USC study shows immigrant adults with liver cancer have higher survival rates than those born in the US

A new study from the USC Norris Comprehensive Cancer Center found that immigrant adults with liver cancer have a significantly higher five-year survival rate compared to those born in the US. The study identified disparities in survival rates across different racial and ethnic groups, with immigrants demonstrating better outcomes.

SourceKeck School of Medicine of USC·TypeMeta-analysis·DateMay 10, 2023

NRG Oncology combined trial long-term results indicate that pathologic complete response is prognostic of outcomes for soft tissue sarcoma patients

The NRG Oncology combined trial results indicate that pathologic complete response (pCR) is associated with improved survival outcomes for patients with localized soft tissue sarcoma. pCR can be used as a prognostic factor for clinical outcomes in future STS research, with patients achieving higher overall and disease-free survival rates.

SourceNRG Oncology·JournalJAMA Oncology·DateMar 31, 2023

A 4-drug chemotherapy regimen improves survival in stage 4 pancreas cancer

A Phase 3 clinical trial has shown that a four-drug chemotherapy regimen significantly increases overall survival and progression-free survival in patients with stage 4 pancreatic ductal adenocarcinoma. The study's results suggest that this more aggressive treatment approach may be considered for eligible patients.

SourceUniversity of California - Los Angeles Health Sciences·TypeRandomized controlled/clinical trial·DateJan 20, 2023

Nab-paclitaxel does not extend biliary tract cancer survival, but may benefit some

A phase 3 trial found that adding nab-paclitaxel to a standard gemcitabine plus cisplatin regimen did not significantly extend median overall survival for patients with advanced biliary tract cancers, but provided benefits for subsets of patients. The treatment also showed improved response rates and progression-free survival times.

SourceSWOG Cancer Research Network·TypeRandomized controlled/clinical trial·DateJan 20, 2023

Study shows how turtles fared decade after oil spill

Researchers confirm that turtles rehabilitated in the aftermath of the Kalamazoo River oil spill had high long-term survival rates, with up to 11 years post-spill showing nearly imperceptible differences in monthly survival probability. The study's findings suggest that rehabilitation efforts increased the monthly survival probability ...

SourceUniversity of Toledo·JournalEnvironmental Pollution·TypeExperimental study·DateSep 27, 2022

IMPower010: Overall survival interim analysis of a Phase III study of atezolizumab vs best supportive care in resected NSCLC

The IMpower010 trial showed an overall survival trend in favor of atezolizumab in the PD-L1 TC ≥1% stage II-IIIA population, with a clinically meaningful improvement observed across most subgroups. The study found no separation for the ITT population or all-randomized, stage II–IIIA populations.

BU study: Stem cell transplantation for AL amyloidosis leads to long-term survival and possible cure in selected patients

Researchers at Boston University School of Medicine found that high-dose chemotherapy and autologous stem cell transplantation can produce prolonged survival in patients with AL amyloidosis. The study developed a predictive score to assess event-free survival, which showed improved safety and effectiveness for selected patients.

SourceBoston University School of Medicine·JournalAmerican Journal of Hematology·TypeData/statistical analysis·DateJul 14, 2022

New report underscores importance of health insurance status and cancer stage at diagnosis and survival

A new report by the American Cancer Society shows individuals without health insurance coverage were more likely to be diagnosed with late-stage cancer and have worse survival rates. Uninsured individuals diagnosed with Stage I disease had worse survival rates for six cancers compared to those with private health insurance.

SourceAmerican Cancer Society·JournalJournal of General Internal Medicine·DateJul 13, 2022

PSA-based endpoints should not be used as surrogate endpoints for overall survival in men with recurrent prostate cancer at this time

A study published in the Journal of Clinical Oncology found that biochemical failure is not a reliable surrogate endpoint for overall survival in patients with recurrent prostate cancer. The researchers recommend considering metastasis-free survival (MFS) as the best surrogate endpoint for overall survival in this population.

SourceNRG Oncology·JournalJournal of Clinical Oncology·DateJun 29, 2022

Delays in surgery for advanced esophageal cancer result in significantly worse survival than early surgery

Patients with stage II/III esophageal cancer who received delayed surgery had a relative survival rate that was almost half that of patients who underwent early surgery. Early-stage cancer patients did not experience significant differences in survival rates between those who received immediate versus delayed surgery.

SourceAmerican College of Surgeons·JournalJournal of the American College of Surgeons·DateMay 12, 2022

ARS-developed Varroa-resistant honey bees better winter survivors

A study published in Scientific Reports found that ARS-developed Pol-line honey bees have a significantly higher winter survival rate than standard honey bees, with rates of 62.5% and 3%, respectively. Additionally, Pol-line colonies showed lower levels of three major viruses commonly transmitted by Varroa mites.

SourceUS Department of Agriculture - Agricultural Research Service·JournalScientific Reports·TypeObservational study·DateApr 7, 2022

How does perennial grassland cover affect duck nest survival?

A new study published in The Journal of Wildlife Management found that perennial grassland cover affects duck nest survival differently depending on its dominance as a landcover type. In the Prairie Pothole Region, intermediate levels of perennial cover (30–60%) showed no additional benefits for nest survival.

SourceWiley·JournalJournal of Wildlife Management·DateApr 6, 2022