A team of researchers has genetically engineered cancer-killing immune cells to hunt brain tumors displaying CSPG4, a highly prevalent molecular target. The approach holds promise for controlling tumor growth in glioblastoma patients, who currently have limited treatment options with survival benefits of less than a year and a half.
SourceUNC Lineberger Comprehensive Cancer Center·JournalScience Translational Medicine·DateFeb 28, 2018
Researchers at the German Primate Center have improved DNA transfer in gene therapy by modifying viruses to produce a protein called CD9, which increases exosome production and virus efficiency. This results in an 80% infection rate, making gene therapies more efficient.
SourceDeutsches Primatenzentrum (DPZ)/German Primate Center·JournalMolecular Therapy·DateFeb 15, 2018
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers from Cincinnati Children's Hospital Medical Center and Yokohama City University report a high-volume production method for bioengineered human gut and liver tissues that avoids tumor risks. The new approach uses genetically stable posterior gut endodermal progenitor cells, which can be programmed to form different tissue ty...
SourceCincinnati Children's Hospital Medical Center·JournalStem Cell Reports·DateFeb 8, 2018
Researchers have developed a novel technology platform to genetically modify phage genomes systematically, providing additional functionality. The new phage workbench allows for the creation of custom bacteriophages with various functions, overcoming constraints associated with naturally occurring phages.
SourceETH Zurich·JournalProceedings of the National Academy of Sciences·DateFeb 6, 2018
Researchers at UT Southwestern's Simmons Cancer Center have made a historic breakthrough in CAR-T therapy for acute lymphoblastic leukemia (ALL) in children and young adults. Eighty-one percent of patients treated with CAR-T therapy went into remission, offering new hope for those previously untreatable.
SourceUT Southwestern Medical Center·JournalNew England Journal of Medicine·DateFeb 1, 2018
A global study by researchers at Senckenberg Nature Research Society and Goethe University Frankfurt found that mammals cover half to one-third of their usual distances in human-modified areas. This reduction affects ecosystem functions, including nutrient transport and species interactions.
SourceGoethe University Frankfurt·JournalScience·DateJan 25, 2018
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
Researchers have created the world's first monkey clones using somatic cell nuclear transfer (SCNT), a technique that made Dolly the sheep. The cloned monkeys, Zhong Zhong and Hua Hua, are genetically identical long-tailed macaques born recently at the Chinese Academy of Sciences Institute of Neuroscience in Shanghai.
Researchers at Max Delbrück Center find GRHL2 protein crucial for concentrating urine and maintaining salt levels in the kidneys. Genetically modified mice lacking GRHL2 produce more diluted urine, highlighting its importance for regulating body fluids.
SourceMax Delbrück Center for Molecular Medicine in the Helmholtz Association·JournalJournal of the American Society of Nephrology·DateDec 13, 2017
A team of researchers from the University of Bristol has successfully transplanted genetically modified olfactory ensheathing cells that secrete a treatment enzyme, promoting nerve regrowth in rodent models of spinal cord injury. This approach may potentially lead to improved recovery and functional restoration for individuals with sev...
SourceUniversity of Bristol·JournalPLOS ONE·DateDec 11, 2017
A new PET tracer has been developed to effectively gauge the effectiveness of promising Alzheimer's treatments in mouse models. The tracer binds to BACE1, a key enzyme involved in amyloid-β development, and accurately measures its effects on brain metabolism, neuroinflammation, and amyloid-β pathology.
SourceSociety of Nuclear Medicine and Molecular Imaging·JournalJournal of Nuclear Medicine·DateDec 6, 2017
A Japanese research team developed a refrigeration preservation technology that extends mouse sperm freezing period from three days to 10 days. This breakthrough enables safe and easy transportation of genetically modified mice worldwide, accelerating international collaborative research.
SourceKumamoto University·JournalBiology of Reproduction·DateDec 4, 2017
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SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A team of scientists discovered that a major cause of variation between genetically identical C. elegans worms is their mother's age, particularly in younger mothers. The study found that the youngest mothers produce offspring with impaired characteristics such as size, growth rate, and starvation resistance.
SourceCenter for Genomic Regulation·JournalNature·DateNov 30, 2017
A study by Rutgers University researchers suggests that gut bacteria at a young age contributes to the onset and progression of Multiple Sclerosis (MS). The study found that genetically engineered mice exposed to normal environment developed MS-like disease, highlighting the role of gut bacteria in triggering immune system changes.
SourceRutgers University·JournalProceedings of the National Academy of Sciences·DateNov 17, 2017
Researchers developed and grew modified Cavendish bananas resistant to Fusarium wilt tropical race 4 (TR4), a devastating soil-borne fungus. One line remained TR4-free for three years, while three others showed strong resistance.
SourceQueensland University of Technology·JournalNature Communications·DateNov 14, 2017
A new gene therapy has shown significant improvements in vision for patients with Leber congenital amaurosis, a rare inherited retinal disease. The treatment, currently under FDA review, allows patients to navigate mazes and experience improved light sensitivity and peripheral vision.
A boy suffering from extensive skin damage due to epidermolysis bullosa was successfully treated with genetically modified stem cell transplants. The treatment resulted in the growth of high-quality, stress-resistant skin, allowing him to attend school and participate in social life.
SourceRuhr-University Bochum·JournalNature·DateNov 8, 2017
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Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
Research suggests that amyloid-beta, a toxic protein, can travel to the brain from other parts of the body, contributing to Alzheimer's disease. This discovery offers hope for new drug therapies that target the kidneys or liver to prevent the protein from reaching the brain.
SourceUniversity of British Columbia·JournalMolecular Psychiatry·DateOct 31, 2017
Scientists found that skin helps regulate blood pressure and heart rate in response to changes in oxygen availability. In mice genetically modified to lack certain HIF proteins, the response to low-oxygen conditions was altered, affecting heart rate, blood pressure, and overall activity.
Human exposure to glyphosate has increased significantly since the introduction of genetically modified crops, with 70% of study participants having detectable levels by 2016. Glyphosate use has also increased 15-fold since 1994.
SourceUniversity of California - San Diego·JournalJAMA·DateOct 24, 2017
Researchers found significant increases in glyphosate and its metabolite in the urine of older adults from Southern California between 1993 and 2016. Average glyphosate levels increased by 13 years, with detectable levels present in more than 70% of samples.
Researchers at the University of Minnesota have developed a promising approach called synthetic incompatibility to prevent interbreeding between genetically engineered and unaltered organisms. This technology effectively makes engineered organisms a separate species unable to produce viable offspring.
SourceUniversity of Minnesota·JournalNature Communications·DateOct 12, 2017
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
Researchers at Scripps Research Institute have developed a method for creating modified DNA-based hydrogels with unique properties. These hydrogels can be dissolved, reformed, and retain their biochemical activity, making them suitable for various applications such as drug delivery and cell growth.
SourceScripps Research Institute·JournalAngewandte Chemie·DateOct 11, 2017
A global assessment reveals that genetically engineered crops producing insect-killing proteins from Bacillus thuringiensis have led to a fivefold increase in pest resistance cases over the past decade. However, some pests remain suppressed due to factors such as recessive inheritance of resistance and abundant refuges.
SourceUniversity of Arizona·JournalNature Biotechnology·DateOct 10, 2017
Researchers compared GM soybean oil to conventional soybean, coconut, and olive oils, finding that GM soybean oil reduces obesity and insulin resistance but causes similar negative effects on diabetes and fatty liver as conventional soybean oil. Olive oil produced identical negative effects to Plenish.
SourceUniversity of California - Riverside·JournalScientific Reports·DateOct 2, 2017
Researchers at Johns Hopkins Bloomberg School of Public Health discover two new strategies to combat malaria: genetically modified bacteria that spread rapidly in mosquito populations and boost the immune system of malaria-carrying mosquitoes. These innovative approaches aim to reduce the need for continuous malaria control measures, p...
SourceJohns Hopkins Bloomberg School of Public Health·JournalScience·DateSep 28, 2017
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Researchers at Johns Hopkins University engineered GM mosquitoes with altered microbiota that suppresses human malaria-causing parasites. The trait was successfully passed along to multiple generations of offspring, even when combined with wild mosquitoes, and maintained for 7 years.
SourceNIH/National Institute of Allergy and Infectious Diseases·JournalScience·DateSep 28, 2017
A modified poliovirus therapy has been found to induce an inflammation process that counteracts cancer cells' ability to evade the immune system. The therapy activates dendritic cells and macrophages, which present tumor antigens to T-cells, launching a targeted immune response.
SourceDuke University Medical Center·JournalScience Translational Medicine·DateSep 20, 2017
A large-scale genetic study of Papuan New Guinean people found strong genetic differences between groups, reflecting linguistic and cultural diversity. The study suggests that the country's isolated highlands region has remained genetically independent for thousands of years.
SourceWellcome Trust Sanger Institute·JournalScience·DateSep 14, 2017
A chemically modified version of heparin shows promise in reducing brain swelling and inflammation after traumatic brain injury in mice. The new treatment, ODSH, is being tested in a Phase II clinical trial to assess its effectiveness in people with TBI.
SourceUniversity of Pennsylvania School of Medicine·DateSep 13, 2017
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
Researchers have observed unusual neural activity in some genetically modified lab mice widely used in neuroscience research. This abnormal activity may be linked to the expression of a genetically-encoded calcium sensor during development.
SourceSociety for Neuroscience·JournaleNeuro·DateSep 4, 2017
Scientists use nonlinear reaction-diffusion equations to model gene movement and develop 'switches' that initiate and terminate gene drives, balancing genetic traits with embedded weaknesses. They also find that intense release in specific regions can trigger spreading, but can be stopped by barriers like pesticides.
SourceHarvard John A. Paulson School of Engineering and Applied Sciences·JournalProceedings of the National Academy of Sciences·DateAug 1, 2017
A mouse model of autism shows that social environment influences behaviors characteristic of ASD. Housing genetically modified mice with unmodified littermates alters their behavior, highlighting the impact of social hierarchy on ASD-like traits.
SourceSociety for Neuroscience·JournaleNeuro·DateJul 31, 2017
Researchers at Dartmouth's Norris Cotton Cancer Center have discovered a novel synthetic lethality screen to discover molecules that target genetically modified yeast lacking NF1. The team identified one lead candidate called Y100, which disrupts tumor cell growth and induces oxidative stress causing death of NF1-deficient cancer cells.
SourceDartmouth Health·JournalOncoTargets and Therapy·DateJul 20, 2017
Researchers found genetically modified CAR T cells successfully migrated to and penetrated glioblastoma tumors, but triggered an immunosuppressive tumor microenvironment. To overcome resistance, existing immunotherapies targeting checkpoint inhibitors may be necessary.
SourceUniversity of Pennsylvania School of Medicine·JournalScience Translational Medicine·DateJul 19, 2017
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Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
Researchers have developed a simple methodology to capture proteins implicated in Alzheimer's disease and other conditions. The new method uses engineered tails to trap sugar-modified proteins, which can then be identified using routine laboratory techniques.
A recent study analyzing over half of the malaria parasite's genes found that two thirds are essential for survival, opening up new avenues for antimalarial drug development. The researchers developed a method to decipher gene function by switching off and counting the growth of genetically modified parasites.
SourceWellcome Trust Sanger Institute·JournalCell·DateJul 13, 2017
Researchers developed genetically enhanced cord-blood derived immune cells to target B-cell malignancies, boosting persistence and embedding a suicide gene. The engineered natural killer cells showed improved efficiency in killing cancer cells and extended survival in mouse models.
SourceUniversity of Texas M. D. Anderson Cancer Center·JournalLeukemia·DateJul 13, 2017
A study published in the European Heart Journal shows a vaccine that lowers cholesterol may be effective in preventing cardiovascular disease. The AT04A vaccine, administered to genetically modified mice, reduced cholesterol levels by 53% and induced long-lasting antibodies against PCSK9, an enzyme contributing to high cholesterol.
SourceEuropean Society of Cardiology·JournalEuropean Heart Journal·DateJun 19, 2017
Researchers have developed a new method to control fire blight by using a genetically modified bacteriophage (Y2) that can dissolve the slime layer protecting the Erwinia bacteria and kill it. Additionally, another variant of Y2 has been engineered to detect Salmonella by emitting light when bound to infected bacteria.
SourceETH Zurich·JournalApplied and Environmental Microbiology·DateJun 13, 2017
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
Researchers at Hiroshima University have developed a highly safe and practical biocontainment strategy for GMOs, utilizing a phosphite-based control method. The new method has shown promise in reducing the risk of GMO escape and proliferation, making it an attractive solution for legislators to consider.
SourceHiroshima University·JournalScientific Reports·DateJun 7, 2017
Researchers at Oregon State University developed two new modified toy car designs to encourage children with disabilities to engage in physical and social activities. The sit-to-stand car promotes standing up to activate the switch, while the Throw Baby Throw car uses a pitching machine to facilitate throwing skills.
SourceOregon State University·JournalFrontiers in Robotics and AI·DateMay 24, 2017
Researchers aim to genetically modify human bone marrow cells to produce more bone morphogenetic protein, a key factor in bone healing, to tackle challenging bone repairs such as extensive fractures and failed spinal fusions. The five-year grant will support the study's efficacy and safety assessment.
SourceUniversity of Southern California - Health Sciences·DateMay 23, 2017
Research in The FASEB Journal reveals a key role for cilia structure in determining susceptibility to neural tube defects. Genetically modified mice studies found that methylation of the Septin2 protein affects neural tube closure, leading to an increased risk of birth defects.
SourceFederation of American Societies for Experimental Biology·JournalThe FASEB Journal·DateMay 11, 2017
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
A new technique uses modified insulin and red blood cells to regulate blood sugar levels in mice with Type 1 diabetes. The system effectively reduces blood sugar levels for 48 hours and has shown promise in reducing the risk of hypoglycemia.
SourceNorth Carolina State University·JournalAdvanced Materials·DateMay 8, 2017
A study published in the Proceedings of the National Academy of Sciences reveals that interbreeding genetically engineered cotton with non-Bt cotton can delay and even reverse evolution of resistance by pests. This novel strategy involves planting a mix of Bt and non-Bt seeds, which generates a random mixture of plants within fields.
SourceUniversity of Arizona·JournalProceedings of the National Academy of Sciences·DateMay 8, 2017
Scientists successfully completed the first EPA-approved outdoor field trial for genetically engineered algae, testing a strain in real-world conditions without adverse impact on native populations. The study demonstrates the feasibility of cultivating genetically engineered algae outdoors while maintaining engineered traits.
SourceUniversity of California - San Diego·JournalAlgal Research·DateMay 4, 2017
Researchers have engineered soybeans to withstand increased temperature and carbon dioxide levels, resulting in higher yields in future climate conditions. The modified crops outperformed conventional soybeans in field studies conducted at SoyFACE, a facility emulating future atmospheric conditions.
SourceCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign·JournalJournal of Experimental Botany·DateMay 3, 2017
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Joslin Diabetes Center researchers found impaired insulin effects boost cancer risks in mice with genetically modified intestinal tumors and blood vessels. Insulin resistance may impair blood vessel health and share biological mechanisms with cardiovascular disease.
SourceJoslin Diabetes Center·JournalOncogene·DateMay 1, 2017
A new study by Tel Aviv University researchers links cannabis use in adolescence to an increased risk of developing schizophrenia. The research found that psychoactive compound THC triggers brain defects associated with the disorder in genetically susceptible individuals.
SourceAmerican Friends of Tel Aviv University·JournalHuman Molecular Genetics·DateApr 26, 2017
Researchers found that genetics controlled which receptors were present in mice, but the environment also played a significant role in shaping the olfactory system. This combination of genetic and environmental factors gives each individual a unique sense of smell, even among genetically identical animals.
Saiful Chowdhury, UTA assistant professor, develops new mass spectrometry techniques to identify prenylated proteins linked to cancer, aging, and genetic disorders. His work may lead to more efficient analysis of modified proteins and improved understanding of cancer mechanisms.
SourceUniversity of Texas at Arlington·JournalJournal of the American Society for Mass Spectrometry·DateApr 20, 2017
Sky & Telescope Pocket Sky Atlas, 2nd Edition
Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.
A promising artificial blood substitute has been developed using modified hemoglobin, effectively carrying oxygen and scavenging free radicals. The novel approach packaging hemoglobin in a benign envelope overcomes toxicity issues with traditional chemically modified hemoglobin.
SourceAmerican Chemical Society·JournalBiomacromolecules·DateApr 19, 2017
A new study has identified novel mechanisms by which T cells recognize emerging class of targets specifically increased on cancer cells. The study found that phosphorylation induces a major change in peptide structure and makes the critical receptor sensitive to discrimination between modified and non-modified peptides.
SourceUniversity of Birmingham·JournalOncoTargets and Therapy·DateApr 13, 2017
A new analytical tool developed by University of British Columbia researchers provides accurate estimates of genetically modified pollen spread to non-modified crops. This enables the calculation of optimal separation distances to minimize cross-pollination, benefiting both crop-growers and policymakers.
SourceUniversity of British Columbia Okanagan campus·DateApr 10, 2017
A modified Fistula Risk Score (FRS) based on ACS NSQIP data helps surgeons identify high-risk patients for anastomotic leak after pancreas resection. The risk score also assesses the quality of patient care and evaluates new interventions to prevent fistula development.
SourceAmerican College of Surgeons·JournalJournal of the American College of Surgeons·DateApr 10, 2017
Researchers found that aneuploidy, a condition causing abnormal chromosome numbers, can lead to varying outcomes in genetically identical cells. The study's findings have significant implications for cancer treatment, as it may explain why some cancer cells respond differently to therapy.
SourceMassachusetts Institute of Technology·JournalCell·DateApr 6, 2017
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
A team of researchers has successfully engineered sugarcane to produce oil in its leaves and stems, resulting in higher oil content without compromising sugar production. This breakthrough could lead to the development of dual-purpose bioenergy crops that are more profitable and sustainable than traditional soybeans and corn.
SourceCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign·JournalBiocatalysis and Agricultural Biotechnology·DateApr 4, 2017
Researchers at INRS-Institut Armand-Frappier Research Centre have developed a strategy to increase the antimicrobial activity of cationic peptides against biofilms. The modified peptide demonstrated a 60-fold enhanced antimicrobial effect, paving the way for potential therapy combinations with clinically relevant antibiotics.
SourceInstitut national de la recherche scientifique - INRS·JournalPLOS ONE·DateApr 3, 2017
Researchers developed a gene therapy that restored balance and hearing in genetically modified mice with Usher Syndrome. The study's positive results suggest potential for treating various inherited vestibular and hearing disorders in humans.
SourceJohns Hopkins Medicine·JournalMolecular Therapy·DateMar 23, 2017
Scientists at IDIBAPS and IRB Barcelona developed a novel strategy to genetically modify viruses that selectively target tumor cells while sparing healthy tissue. The study's results show promising effectiveness in controlling tumor growth and destroying cancer cells, offering hope for new cancer therapies.
SourceInstitute for Research in Biomedicine (IRB Barcelona)·JournalNature Communications·DateMar 16, 2017
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.