A new study reveals that bacteria in biofilm form are stronger than single-celled bacteria and outcompete them for nourishment. This challenges the traditional view of bacterial infections and highlights the importance of treating biofilms as a distinct entity.
Scientists at the University of Copenhagen have discovered a previously unknown weakness in bacteria, known as an 'Achilles heel', which is a proton leak state. This discovery may lead to the development of novel antibiotics by targeting this safety valve in bacterial energy metabolism.
A study led by the University of Edinburgh's MRC Centre for Inflammation Research discovered a mechanism to keep bacteria in the gut. The researchers found that PGE2 activates innate lymphoid cells, which help maintain the gut barrier and prevent body-wide inflammation.
Researchers at the University of Missouri have discovered a unique microbiome in the male reproductive tract that harbors harmful bacteria, which may negatively influence reproductive function and health. The bacteria found in this microbiome may pass from father to offspring, programming later disease risk such as obesity.
A new study reveals that a more primitive form of photosynthesis evolved in much older bacteria than previously thought, dating back to around 3.5 billion years ago. This type of photosynthesis does not produce oxygen and uses molecules such as hydrogen or iron as fuel.
Researchers found that bacteria in roundworms are loyal to their hosts, while those in segmented worms prefer local locations, with external tenants showing more long-term loyalty than internal cohabitants.
A large-scale study reveals that premature babies with necrotizing enterocolitis have a distinct mix of gut microbes compared to healthy infants. The researchers identified Gram-negative bacteria and anaerobic bacteria as potential contributors to the disease, and found that breast milk may offer some protection.
Researchers from KU Leuven found that frequent antibiotic use leads to the development of persister cells, which are dormant and tolerant to antibiotics. This phenomenon can lead to the recurrence of infections despite successful treatment.
Scientists are studying graphene oxide to create bacteria-killing catheters and medical devices, reducing the need for antibiotics and speeding recovery times. Graphene oxide wraps around bacteria, puncturing its membrane and killing it, making it a potential alternative to traditional methods that are toxic to the environment.
A study by Dr. Fraser Scott and his team discovered a bacteria-killing protein called cathelicidin antimicrobial peptide (CAMP) that helps the pancreas regenerate and produce insulin. The research could lead to novel treatments for both type 1 and type 2 diabetes.
Researchers discovered that E. coli uses bio-films to protect itself from the bacterial predator Bdellovibrio bacteriovorus, allowing it to survive in fragmented environments. This finding could lead to the development of alternative antibiotics that target specific harmful bacteria while leaving benign ones untouched.
A study presented at the American Stroke Association's International Stroke Conference 2016 found that restoring gut bacteria to a youthful age was linked to improved stroke recovery in old mice. Researchers used fecal transplants to deliver a 'young' set of bacteria to mice with induced strokes, resulting in better recovery rates.
A critical discovery about how bacteria feed on an unusual sugar molecule found in leafy green vegetables could hold the key to explaining how 'good' bacteria protect our gut and promote health. Leafy greens are essential for feeding good gut bacteria, limiting the ability of bad bacteria to colonise the gut.
Research reveals that chronic drinking also promotes the growth of gut bacteria that can travel to the liver and exacerbate liver disease. The study found that boosting intestinal defense against certain bacteria may help patients with alcoholic liver disease.
Researchers identify RimK as a crucial regulator of bacterial movement, which is essential for initiating infections. Disabling this protein significantly reduces the ability of bacteria to infect plants and humans, offering a new target for anti-infective drugs.
Researchers at Forsyth Institute use a new imaging technique to visualize bacteria in dental plaque, revealing the formation of 'hedgehog' structures that suggest functional roles within the community. This study provides critical insights into how mouth microbes interact and will help understand their role in health and disease.
A University of Hawaii research team will investigate how specific strains of bacteria from marine biofilms induce the settlement and metamorphosis of a small tube worm. The goal is to understand the factors produced by the bacteria that cause the larvae to settle and undergo dramatic physical changes.
Researchers at Washington University in St. Louis have identified a virulence factor secreted by the bacterium Acinetobacter baumannii, which is resistant to traditional antibiotics. The discovery could lead to the development of new antivirulence antibiotics that can suppress pathogen growth without eliminating susceptible bacteria.
New research reveals that skin bacteria toxins can advance cancer cell growth by manipulating the immune system. The study found that certain staphylococcus bacteria produce toxins that enable cancer cells to override the immune defense mechanism, leading to more aggressive disease progression.
Researchers discovered a unique antibiotic molecule that triggers a bacteria's adaptation strategy, enabling it to resist the drug. The resistant bacteria undergoes morphological changes and can move away from the antibiotic, allowing it to survive and spread.
Researchers discovered that millions of bacteria in water pipes and purification plants help purify drinking water. The diversity of species is huge, with over 80,000 bacteria per milliliter detected in one study.
A collaboration between computer scientists and geneticists at Stanford University has produced a novel technique for mapping the diversity of bacteria living in the human gut. The new approach revealed a far more diverse community than the researchers had anticipated, with many different strains of the same species identified.
Scientists at the Max Planck Institute found that cooperating bacteria form cell clusters to exclude non-cooperating bacteria from their community. This mechanism stabilizes long-term partnerships without requiring complex recognition of potential partners.
Researchers found that metformin treatment leads to favourable changes in gut microbiota, increasing the production of health-promoting short-chain fatty acids. However, other antidiabetic drugs showed no impact on gut bacteria, contradicting previous research findings.
Researchers found that an impaired immune system alters the composition of gut bacteria and affects its evolutionary pace. The study suggests personalized therapies based on individual gut bacteria composition may be more effective than generalist treatments for inflammatory bowel disease.
Researchers identified highly resistant bacteria in 23 of 500 acute care hospital admissions from nursing homes, with a feeding tube associated with gastrointestinal carriage. This study emphasizes the importance of hospital and nursing home infection control measures to prevent the spread of antibiotic-resistant bacteria.
Researchers at UMass Amherst have identified a key molecule in nitrogen-fixing bacteria that may hold promise for improving crop yields without increasing fertilizer use. The discovery of the 'double agent' peptide could be a key factor in future efforts to improve legume crops and promote sustainable farming practices.
The new guidelines aim to prevent the spread of MDRGNB in healthcare settings, which are already present in the UK. They provide practical advice on identifying patients with these bacteria and preventing their spread.
Researchers from NTU Singapore have successfully used dead bacteria to destroy colon tumour cells effectively. The study published in Scientific Reports shows that the secretions of dead Clostridium sporogenes bacteria can reduce the growth of colorectal cancer cells by up to 83%.
Researchers created a synthetic model of E. coli's outer membrane, providing unprecedented access to its structure and dynamics. The model was used to test how antibiotic molecules can cross the critical barrier, which is highly impermeable to incoming molecules.
A mathematical model reveals that competition between beneficial bacteria helps maintain the stability necessary for a healthy gut. By suppressing overabundant bacteria and keeping different species apart, hosts can intervene to maintain this natural balance.
Research found that composting is most reliable to kill bacteria with resistance genes in cow manure. Composting speeds up decomposition and reduces volume of manure. Manure management practices like composting and stockpiling can make it difficult for resistant bacteria to travel from farm to environment.
Researchers at Virginia Tech found that naturally occurring bacteria on a frog's skin can respond to infection and adjust their structure and function to compensate for it. The study suggests that the whole community of bacteria is important, not just a single protective bacterium. This discovery offers hope in limiting the impact of c...
New Danish research reveals that wastewater treatment plants contain a vast pool of genes providing bacteria with antimicrobial resistance, but these genes are rarely found in hazardous bacteria. The study challenges the common perception that wastewater treatment plants are hotbeds for the spread of antimicrobial resistance genes.
Researchers believe ancient bacteria found in 20 million-year-old fossil may be related to Yersinia pestis, the bubonic plague. The discovery suggests plague may have been around for millions of years before humans existed.
Researchers have engineered viruses to target specific bacteria, offering a new approach to combatting human disease. The customizable viruses could be used to treat various infections, including those caused by E. coli, Yersinia, and Klebsiella bacteria.
A bioelectronic nose that mimics the human nose can detect traces of bacteria in water by smelling it, without complex equipment. The sensor is sensitive to low levels of contamination, making it more useful than existing methods.
Researchers at the University of Bonn successfully eliminated multi-resistant bacteria from a pig stable using radical hygiene measures, including frequent hand washing and quarantine. While MRSA was not eradicated, overall health improvement led to reduced antibiotic use, highlighting potential applications for hospitals
A new microfluidic technology enables rapid separation of antibiotic-resistant from susceptible bacteria, offering a game-changing solution for patients. This breakthrough could lead to faster and more effective treatment, reducing mortality rates and improving patient outcomes.
Rice University scientists have created a multicellular bacterial circuit that allows bacteria to cooperate and control protein expression. This breakthrough enables the development of biological computers that can be programmed through diet, with potential applications in treating diseases and manipulating the gut microbiome.
Researchers at UCSB have discovered a mechanism by which gram-negative bacteria deliver protein toxins to their neighbors, killing them. This finding could lead to the development of targeted antibiotics that leave beneficial bacteria in the gut intact.
Scientists have discovered that an infection caused by the Burkholderia bacteria transforms non-farming social amoebae into farmers. These farmer amoebae gather bacteria, carry them to new sites and seed the soil with them, showcasing a complex symbiotic relationship between all three partners.
Researchers found that bacteria in different lung regions evolved distinct traits, including antibiotic resistance and virulence, affecting patient health. The study suggests that understanding this bacterial diversity could lead to new treatments for chronic infections.
Researchers are uncovering how bacteria acquire antibiotic resistance genes through conjugation, a process that involves exchanging genetic material with other microbes. Understanding this mechanism could lead to the development of more effective treatments, such as phage therapy, which uses viruses to target bacterial infections.
Researchers have identified a protective mechanism used by beneficial bacteria to safeguard intestinal cells from stress and damage. By stimulating the Nrf2 pathway, these bacteria can help prevent weight loss and death after radiation exposure, as well as protect against toxic herbicides like paraquat.
Researchers have discovered a potential new class of antibiotics inspired by sugar molecules produced by bacteria, offering a new hope in the fight against drug-resistant superbugs. The modified sugar molecules target a crucial part of the bacterial cell wall, killing the bacteria without developing resistance.
A Virginia Tech scientist has developed a mathematical model that demonstrates bacteria can control the behavior of robots, opening up new possibilities in ecology, biology, and robotics. The model uses engineered gene circuits in E. coli to create a bacteria-robot system that exhibits unique decision-making behavior.
Research found that bacteria shapes changed from sticks to spheres to evade the immune system, revealing a key gene responsible for this transformation. This discovery could lead to new tools for preventing and treating respiratory infections.
Researchers discovered that multidrug-resistant Acinetobacter baumannii can voluntarily relinquish its antibiotic-resistance genes, making it susceptible to existing antibiotics. This finding provides new strategies for combating the growing problem of antibiotic resistance.
A team of researchers has identified the first known exopolysaccharide receptor gene in plants, allowing them to distinguish between beneficial and harmful bacteria. This discovery has significant implications for agricultural research and medical science.
A study found that severe burns alter bacteria populations dramatically, leading to a decrease in beneficial bacteria and an increase in potentially harmful Enterobacteriaceae. This imbalance may contribute to sepsis and other infectious complications in burn patients.
Researchers at Rutgers University found a strain of bacteria that can breathe uranium, which makes it immobile and prevents contamination of drinking water. The discovery holds promise for cleaning up polluted groundwater at sites where uranium ore was processed to make nuclear weapons.
Researchers developed a new model to predict harmful bacteria levels on beaches, using information on waves, tides, and rainfall. The model provides beach managers with an easily accessible computer tool to identify when closures are required to protect human health.
Research found that 90% of bacteria on human skin are either dead or inactive, with different areas harboring varying proportions of metabolically active, inactive, and dead microbes. Activity levels decreased with age, suggesting a possible relationship between the microbiome and immune system function.
Researchers at the University of Missouri have discovered a type of grass, Setaria viridis, that can fix nitrogen using bacteria, making it a potential model for studying this process in crops like corn and rice. This discovery could lead to more efficient use of fertilizer and promote sustainable agriculture.
Researchers at the University of Iowa have found that prolonged exposure to Staphylococcus aureus bacteria causes insulin resistance and glucose intolerance in rabbits, mirroring the symptoms of type 2 diabetes. Anti-bacterial therapy or vaccines may hold promise for preventing or treating the disease.
A study published in Chemical Communications suggests that a natural plant chemical called trans-chalcone can help prevent tooth decay. By blocking the action of an enzyme that allows bacteria to thrive, researchers found that trans-chalcone prevents the formation of plaque and biofilms around teeth.
Researchers at the University of Georgia have found that Tokay geckos harbor bacteria resistant to multiple antibiotics, posing a risk to pet owners. The study highlights the importance of pathogen screening in the pet trade to prevent antibiotic-resistant bacteria from entering households.
A new study led by researchers at the University of Minnesota has found a three-way link among infant antibiotic use, changes in gut bacteria, and disease later in life. The study developed a predictive model for measuring healthy development of bacteria in young children.
Researchers discovered that certain bacteria can block their own growth and that of resistant mutants, providing a potential new strategy to combat antibiotic resistance. This finding could lead to improved treatments for infections caused by resistant bacteria.