Researchers have created a novel monomer that allows for the synthesis of poly(disulfide)s with arbitrary side-chain structures through domino polymerization. The polymers exhibit degradability in reducing environments, including biological systems, making them suitable for drug delivery systems and medical applications.
Researchers at Osaka Metropolitan University identified the tegmentum region as the area where light signals from the eyes and pineal organ are integrated. This integration enables fish to swim up or down based on differences in light wavelength, aiding survival decisions.
A single-celled predator, Rapaza viridis, retains chloroplasts from prey algae and imports host-made proteins into them, revealing deeper levels of host–organelle integration. This process may have played a role in the emergence of plant cells.
Scientists at Osaka Metropolitan University developed high-performance lead-free piezoelectric thin films directly on standard silicon wafers. The films achieved the highest piezoelectric response ever reported for bismuth ferrite, enabling a fivefold improvement in energy conversion efficiency.
A novel drug delivery system developed by Osaka Metropolitan University improves Paclitaxel absorption by binding to the lipocalin-type prostaglandin D synthase enzyme, enabling selective delivery to cancer tissues. The system demonstrates significant tumor suppression effects even after administration cessation.
Researchers discovered a freshwater alga that captures far-red light for photosynthesis by rearranging ordinary chlorophyll. This unique strategy allows the alga to thrive in shaded forests and murky waters, making it resilient in tough environments. The findings have practical implications for sustainable bioenergy production and may ...
Researchers at Osaka Metropolitan University discovered how shifting electric fields control light-emitting efficiency in devices like LEDs. By probing electron spin resonance, they found optimal electric field conditions for efficient recombination, leading to higher electroluminescence efficiency.
A study published in American Journal of Physiology-Endocrinology and Metabolism found that low testosterone and high fructose intake synergistically contribute to liver damage in mice. The researchers discovered that changes in gut microbiota led to increased levels of pyruvate, which promotes fat accumulation in the liver.
Researchers developed a new method to predict extreme rainfall in Japan, using Integrated Nested Laplace Approximation - Stochastic Partial Differential Equation (INLA-SPDE), which outperformed traditional kriging methods. The study used hourly precipitation data from 752 meteorological stations across four main islands of Japan and fo...
Researchers at Osaka Metropolitan University found that targeting the glutamine transporter ASCT2 can suppress cell growth and induce apoptosis in synovial sarcoma cells. This study suggests a new approach for treating this aggressive malignant tumor by cutting off its nutrient supply.
Researchers used continuous and integrated readings of methane and ethane to identify overlooked emissions from restaurants, commercial facilities, and private residences. The study highlights the need for technology and policy to fix these hidden sources, which are estimated to be higher on weekdays.
Researchers observed cleaner wrasse recognizing themselves in mirrors and experimenting with it, suggesting advanced intelligence known as 'contingency testing'. The fish also demonstrated flexible, self-referential processing, indicating widespread self-awareness across taxonomic groups, including fish.
A study of 77,947 patients found that those over 80 and with low initial ADL scores benefited from holiday rehabilitation. This suggests prioritizing interventions for elderly and independent individuals can lead to better outcomes.
Researchers investigated e-beam propagation through ionospheric plasma using particle-in-cell simulations. Nonrelativistic e-beams exhibit laminar-to-turbulent transition with beam compression factor quantified for the first time.
Researchers at Osaka Metropolitan University discovered that natto bacteria convert soybean proteins and other substances into supersulfide molecules. Heat-treated soybeans also showed an increase in supersulfides before fermentation, indicating a complex mechanism behind natto's health benefits.
A study found that cultivating tobacco with its wild relative can erase genetic barriers, allowing normally fatal hybrids to survive. This process, called genome shock, neutralizes lethal gene combinations, potentially leading to the creation of new plant species.
Early marine algae like prasinophytes relied on Lhcp, a unique LHC complex with structural differences from plant LHCII. These similarities and differences may have enabled plants to transition from oceans to land, driven by the stabilization of trimer architecture through pigment-protein interactions.
A research team from Osaka Metropolitan University found that optimizing window-to-wall ratio and insulation can reduce energy consumption by up to 27% in subtropical regions. The study provides tailored design guidelines for each climate zone, promoting net-zero energy housing and climate adaptation policies.
Current smokers are more likely to experience four symptoms associated with Long COVID, including arthralgia, chest pain and dyspnea. Dual users of combustible and heated tobacco products also show a stronger correlation with symptoms, suggesting the added use may worsen symptoms.
Researchers have developed a new way to produce fluorescence by using molecular stacking, which can lead to the creation of smarter and more sensitive pressure sensors. The study focused on two crystalline organoboron compounds that exhibit piezofluorochromism, changing color in response to pressure.
A research team at Osaka Metropolitan University successfully realized a new type of Kondo necklace with increased localized spin size, demonstrating a clear phase transition to magnetic order. The study shows that the Kondo interaction promotes magnetism when the localized spin is larger than 1/2.
Osaka Metropolitan University scientists have created a molecule that naturally forms p/n junctions, structures vital for converting sunlight into electricity. The new design offers a promising shortcut to producing more efficient organic thin-film solar cells.
A COVID-19 survey found that young carers experience higher stress levels with greater care responsibilities. However, they also exhibit positive emotions like a sense of accomplishment and pride. The surveys revealed more pronounced emotional responses in 2024, suggesting growing societal understanding and support for young carers.
A research group at Osaka Metropolitan University has pioneered a technology for preparing biodegradable polymer capsules using naturally occurring molecules. The new method produces stable, shelf-life-friendly capsules that can store target molecules and undergo photodegradation upon exposure to light.
A team of researchers at Osaka Metropolitan University has created two models to detect and fix common labeling errors in large radiographic collections. The models achieved high accuracy rates for body-part classification and projection/orientation detection, showing promising results for improving deep-learning models in medical AI.
Researchers at Osaka Metropolitan University developed a new educational program to enhance evidence-based practice (EBP) knowledge and skills among hospital nurses. The study showed significant improvements in EBP knowledge and skills, as well as implementation, compared to the control group.
Researchers at Osaka Metropolitan University engineered yeast to produce 122 times more 2,3-butanediol in high-concentration environments. Gene expression analysis revealed the crucial role of proteasome and peroxisome activation in tolerance.
Researchers at Osaka Metropolitan University have developed a new stem cell medium using only canine-derived genes, enabling the stable cultivation of canine induced pluripotent stem cells. This breakthrough reduces cross-species contamination risks and paves the way for clinical applications in dogs.
A new model developed by Osaka Metropolitan University Assistant Professor Takuya Fujinaga enables robots to accurately pick tomatoes, with an 81% success rate. The system evaluates the ease of harvesting for each tomato, taking into account factors such as fruit clustering and stem geometry.
Researchers at Osaka Metropolitan University discovered that Fibulin-5 levels increase as liver fibrosis advances, enabling earlier diagnosis and treatment. This finding holds promise for developing a more accurate method to detect liver damage in chronic hepatitis C patients.
Researchers from Osaka Metropolitan University found that pre-dissolving CCl₄ in alcohol speeds up its decomposition rate during ultrasonic treatment. High hydrophobic alcohols surface accumulation affects the increase in decomposition rates.
A cross-sectional survey of 29,268 participants found a significant association between dysfunctional breathing and respiratory conditions, as well as non-respiratory diseases like epilepsy. Tobacco use was also linked to increased prevalence of DB, particularly among those with comorbidities.
Researchers have developed a culture medium, 'AR medium,' that transforms canine iPS cells into functional heart muscle cells with contractions. This breakthrough could accelerate the development of regenerative medicine and genetic disease treatments for humans.
A human clinical trial found that consuming black cumin seed powder daily for 8 weeks significantly reduced blood triglycerides, LDL and total cholesterol levels. The study also showed an increase in HDL cholesterol levels, associated with a lower risk of heart problems.
A 7-week randomized controlled trial found that a train fare subsidy program significantly increased daily walking steps among prime-aged adults by 711.43 steps/day for those subsidized with 1000 points. However, middle-aged and older adults did not experience significant increases in step count.
A study by Osaka Metropolitan University found that lecanemab treatment does not change short-term waste clearance function in Alzheimer's patients. The glymphatic system, which carries away metabolic waste like Aβ, is already damaged in AD patients, and treatment may not be enough to restore lost function.
Researchers used molecular dynamics simulations to investigate how polyamides adhere to alumina surfaces, finding that adhesion strength depends on polymer chemistry and surface termination. The study offers practical design guidelines for selecting surface treatments and polymer types, enabling the creation of stronger, lighter joints.
A team of researchers at Osaka Metropolitan University has successfully treated spinal compression fractures in rats using stem cells derived from adipose tissue. The study found that these cells can promote bone healing and regeneration, making them a potential solution for osteoporotic vertebral fractures.
Researchers from Osaka Metropolitan University have discovered that Lawsone, a chemical derived from Lawsonia inermis, can reduce markers of liver fibrosis and promote antioxidant functions in hepatic stellate cells. The study suggests that Lawsone could be used to control and even reverse the effects of fibrosis.
Researchers at Osaka Metropolitan University discovered that marine green algae possess a unique pigment called siphonein, which helps quench triplet states and protect photosynthesis from excessive light. This finding opens the door to developing bio-inspired solar technologies with built-in protective mechanisms.
Researchers developed sulfated yeast to adsorb targeted elements from solutions, absorbing 2.3 times more copper than previous phosphate-modified baker's yeast. The new method effectively desorbs and re-adsorbs metals using hydrochloric acid, providing a sustainable solution for rare earth recovery.
Researchers measured methane and ethane concentrations in Osaka using mobile measurements and found a discrepancy between observed emissions and official estimates. Several areas of elevated methane concentrations were detected, attributed to various overlooked contributors such as industrial plants, restaurants, and biological sources.
Researchers found that specific bacteria, such as Haemophilus parainfluenzae and Fusobacterium species, are associated with AIG-related neuroendocrine tumors. The study suggests that changes in host metabolism occur before alterations in the gastric microbiota, potentially creating a microenvironment that favors tumor growth.
A study by Osaka Metropolitan University found that pairs outperformed individuals in a robotic arm-transporting task when roles naturally emerged. Role specialization was key to superior performance, rather than paired interaction. The research has implications for human-robot collaboration and rehabilitation settings.
A study by Osaka Metropolitan University reveals that community involvement is a powerful driver of acceptance among people with poor health. The research found that increasing the density of stops in residential areas can make demand-responsive transport more accessible to those with limited mobility. The study's findings suggest that...
A study found that longer commutes and smaller living spaces are associated with poor sleep health among Tokyo residents. Housing choices that balance location and size may help improve sleep health, according to researchers at Osaka Metropolitan University.
A novel detection framework, SORA-DET, is introduced for UAV remote sensing, achieving high accuracy and efficiency while being compact and fast. It outperforms large-scale models with up to 88.1% fewer parameters.
A recent study found that cold temperatures combined with mental fatigue impair endurance exercise performance. Individuals experiencing increased subjective fatigue showed decreased performance. The Sympathetic Adrenal-Medullary system is involved in the increase of fatigue rather than the Hypothalamic-Pituitary-Adrenal axis.
Researchers developed an AI model that diagnoses achalasia using plain chest X-rays, outperforming physicians' reviews. The diagnostic performance of the AI model demonstrated higher sensitivity and specificity, enabling early diagnosis and potentially improving treatment efficacy.
A genetic mutation found in East Asian people, ALDH2*2, impairs the detoxification of aldehydes produced by environmental exposure, leading to an 'aldehyde storm' that causes severe liver damage. Healthy choices like increasing antioxidants and limiting smoke exposure may reduce the risk.