Research on making sense of scientific and medical data. Covers AI error-correction, single-cell search engines, optical computing, and measurement reliability.
UVA researchers developed a new tool to analyze genetic data, reducing noise and bias in cancer diagnosis. The tool uses mathematical modeling to identify patterns in chromatin, helping scientists detect tiny numbers of disease cells.
A pooled data analysis of 10 randomized controlled trials involving 1040 women found that acupuncture significantly relieved pain during pregnancy, improved physical function, and quality of life. The therapy was also found to be safe, with no observable major side effects for newborns.
A new study analyzed tumor biopsies from patients with newly-diagnosed germinal center B cell lymphoma and found that CREBBP mutations were associated with lower disease-free survival rates. The researchers identified CLMA as a practical tool to translate experimental findings into clinical applications.
A new study reveals that middle-aged adults faced higher mortality rates during the second year of the COVID-19 pandemic compared to the first year. The researchers attribute this shift to various factors, including the delta variant's impact on younger age groups and decreased preventive care.
The number of Candida auris cases in the EU/EEA nearly doubled between 2020 and 2021, with 11% of cases having no available information on carriage or infection. Early detection is crucial to prevent the spread of this healthcare-associated pathogen.
Researchers at the University of Ottawa have discovered that patients with electrolyte abnormalities are twice as likely to be diagnosed with an eating disorder. This study analyzed Ontario health data between 2008 and 2020, identifying a potential preventative treatment for approximately 1 million Canadians.
A recent meta-analysis published in Human Reproduction Update reveals a significant worldwide decline in sperm counts of over 50% in the past 46 years. The study also shows an accelerated post-2000 decline in sperm counts globally.
A pooled data analysis estimates that 24% of teens and young people engage in unsafe listening practices from personal listening devices and 48% attend loud music venues. This translates to a potential risk of hearing loss for 0.67-1.35 billion young people worldwide.
Research from the University of Kansas found that financial capability can predict positive health outcomes, with higher levels associated with better health measurements. The study highlights the importance of considering both individual financial skills and access to resources in improving population health.
A University of Massachusetts Amherst study found that over 37% of insured Massachusetts residents experienced an insurance transition during the perinatal period. Individuals with Medicaid and Medicaid managed care were more likely to have a transition than those covered by private insurance, suggesting disruptions in continuity of care.
Researchers created a new set of standards, called FAIR, to manage AI models, making them findable, accessible, interoperable and reusable. This standardization enables cross-pollination across teams and reduces duplication of effort, ultimately facilitating scientific discovery.
A new study proposes a scalable, bottom-up approach to developing energy-saving initiatives at the individual level by analyzing real-time energy usage data. The research team developed an energy calculator that can be scaled up to the building- and community-level, enabling more accurate occupant-level measurements.
A new study from the University of Kansas found that while the pandemic disrupted city sustainability efforts in some cases, it also increased focus on certain types of initiatives. Nearly half of cities reported negative effects on program implementation, but 75% said sustainability staffing was not affected.
A recent analysis of the Family Heart Database found that individuals with familial hypercholesterolemia are more likely to receive adequate treatment if they are White, male, and have higher income or education. The study highlights a significant unmet need for improving equity in cardiovascular risk reduction.
Research highlights the significant role emergency departments play in end-of-life care, with nearly one-third of decedents visiting the ED just before death. The study's findings emphasize the need for emergency medicine practitioners to identify patients in need of end-of-life care and provide necessary resources.
A new study led by University of Cincinnati researcher Trisha Wise-Draper found that immunotherapy treatments may worsen COVID-19 disease in patients with baseline immunosuppression. However, patients who received COVID-19 vaccinations had less severe COVID-19 outcomes.
Researchers at University of Jyväskylä used machine learning to predict ACL injuries in elite athletes but found a low overall accuracy rate. The study analyzed the largest data set ever collected and provided valuable insights into the challenges of predicting injuries in individual athletes.
A new study published in Molecular Psychiatry suggests that parental discord and divorce may be indicators of children's genetic risk for future alcohol misuse. Researchers found that exposure to parents' relationship discord or divorce is associated with increased risk of alcohol use disorder symptoms in adulthood.
The study suggests that marketing research should start with real-world problems and observations, developing valid insights through empirical analysis. The authors propose a three-stage approach: Identify Opportunity, Explore Terrain, and Advance Understanding.
A recent analysis of COVID-19-positive donor heart transplants found no significant differences in transplant outcomes compared to those from non-COVID-19 donors. The study's results suggest that COVID-19-positive hearts may be as safe for transplantation, potentially addressing the shortage of available donor organs.
A new study in Cell Systems explores the benefits of using multiple data types in drug discovery. Gene expression and cell morphology provide complementary information for drug prioritization, advancing drug discovery, functional genomics, and precision medicine.
The Regenstrief Institute and Indiana Department of Health are collaborating on an influenza surveillance data pilot study to analyze the spread of Influenza in Indiana. The partnership aims to identify patterns and hot spots throughout the state to inform public health strategies.
Patients taking apixaban had a 43% lower risk of stroke or systemic embolism compared to those taking rivaroxaban. Apixaban also reduced the risk of bleeding events by 49% in patients with atrial fibrillation and valvular heart disease.
Research at the University of Arizona found a strong link between bright color use and ancestral day-night activity patterns. Species that use bright colors for sexual signals were descended from diurnal ancestors, while those using aposematism had nocturnal ancestors. This pattern holds across land vertebrates with over 40,000 species.
The Association for Molecular Pathology (AMP) has published consensus recommendations for using in silico approaches to validate Next-Generation Sequencing (NGS) data analysis pipelines. The guidelines provide expert opinion on the advantages and disadvantages of different types of in silico data and offer general recommendations for s...
A new $1.328M grant will help assess and improve the reporting quality in randomized clinical trial protocols and result publications using NLP methods. The goal is to promote high reporting standards, synthesizing evidence, and open science practices throughout the scientific ecosystem.
Researchers at Osaka University have developed a computational tool called CAPITAL that can carry out accurate comparative analysis of complex single-cell sequencing datasets. The tool uses a pseudotime trajectory approach to align and compare cells along hypothetical paths reflecting their progress through transitional processes.
The CityAccessMap tool assesses urban infrastructure distribution and identifies areas for improvement, helping policymakers address socio-economic disparities. Disadvantaged communities face lower access to urban services, which can hinder social mobility and exacerbate inequalities.
A perspective paper explores the role of clinician-data-scientists in healthcare, emphasizing their need for interdisciplinary knowledge and training. The researchers highlight the importance of integrating data science into conventional medical education to prepare clinicians for the digital health era.
The Critical Path Institute has launched a pre-consortium collaboration with the FDA's CBER and CDER to accelerate medical product development in alpha-1 antitrypsin deficiency. The collaboration aims to define unmet needs in drug development and lay the groundwork for specific solutions.
Researchers aim to shift policing focus from law enforcement to building strong communities through situational policing. The approach considers connections within the community and collaboratively builds resources.
Researchers developed algorithms that can predict volleyball players' actions with over 80% accuracy, combining visual data with hidden variables. The algorithms also showed promise in predicting multiple actions across sequences of up to 44 frames.
A new study from the University of Kansas suggests that fostering positive attitudes toward math and science early in students' lives can address gender and socioeconomic gaps in STEM. The study analyzed data from over 21,000 students and found that having a science or math identity in ninth grade can increase the likelihood of enrolli...
The study explored how humans react to DAVE, a Virtual Labrador, in virtual reality. Researchers found that humans exhibited varying behaviors when interacting with the digital dog, shedding light on canine-human interactions.
Researchers found that air pollutants, particularly fine particles and nitrogen dioxide, increase the risk of COVID-19 hospitalizations up to 30% in vaccinated individuals. Long-term exposure also worsens outcomes, even among those fully vaccinated, highlighting the importance of improving indoor air quality.
Researchers found that all mind-body practices led to significant reductions in blood sugar levels, with yoga providing the largest benefit. The study suggests that these practices could be used as a complementary nonpharmacological treatment or preventive measure for type 2 diabetes.
The 2022 EXPLORE Lunar Data Challenge identifies hazards on the Moon's surface using images from the Lunar Reconnaissance Orbiter. Participants train models to recognize craters and boulders, then create a map of optimal rover routes to avoid hazards.
A study by Colorado State University found that indoor air contains more known human toxins than outdoor air, particularly when cooking or cleaning. The research, called HOMEChem, identified compounds like benzene, formaldehyde, and acrolein as potential health risks.
Researchers reviewed mobile sensing designs, outcomes, and limitations to better understand its capacity for remote detection, longitudinal tracking, and exposure tracing. Despite technical and societal challenges, advances in data analytics and machine learning may improve data quality and scalability.
Researchers developed an electronic laboratory notebook that uses knowledge graphs to describe material properties and experimental processes. The platform enables automated analysis, lossless sharing, and discovery of new materials with potential applications in energy-related devices.
Research institutes from Finland, Germany, Norway, Spain, and Sweden have launched the Federated European Genome-phenome Archive (Federated EGA) to improve data sharing across national borders. The new platform enables secure access to sensitive human data for research while respecting national data protection regulations.
Two new studies published in NEJM Catalyst demonstrate the remarkable effectiveness of telemedicine in addressing access barriers and improving health outcomes. The research highlights the benefits of telemedicine for patients with transportation challenges, mental health services, and overall quality of care.
A new study from Michigan Medicine found that adults with more chronic health conditions are at higher risk of serious financial problems, including late payments, poor credit scores, and bankruptcy. The study analyzed nearly 3 million privately insured adults and found that those with seven or more chronic conditions had three to four...
A study found that many people with health insurance still struggle with medical debt, which can lead to evictions, foreclosures, and food insecurity. The analysis of survey data suggests a significant association between medical debt and worsening social determinants of health.
The Bioteque computational tool integrates vast amounts of biological data, providing insights into gene functions, protein interactions, and disease connections. By analyzing over 30 million functional interactions, the tool can predict drug sensitivity and accelerate biomedical research.
A New York City-based study analyzed over 600,000 household contacts to determine the risks of acquiring SARS-CoV-2 infection after exposure. The research found specific risk factors associated with a higher likelihood of developing COVID-19
A new study published in the Journal of the American Heart Association found that air pollution may trigger irregular heart rhythms in healthy teenagers, with exposure causing arrhythmias to occur within two hours. The research analyzed data from over 300 adolescents and found a significant impact of fine particulate matter on cardiac ...
The US Preventive Services Task Force (USPSTF) states that screening for type 2 diabetes in asymptomatic children and adolescents under 18 has insufficient evidence to support a recommendation. As of 2018, approximately 23,000 children and adolescents had type 2 diabetes, with incidence rates rising.
Researchers found that dark matter halos in ultra-diffuse galaxies have lower concentrations than expected, raising questions about their formation and evolution. The study's surprising results indicate these galaxies may be younger and contain more gas than normal galaxies.
A UConn study found that Connecticut's notification system for substance-ex exposed infants has connected over half of identified cases with community supports and services. The system, which uses de-identified data, has shown promise in reducing disparities in testing and reporting, but there is still room for improvement.
A study published in Injury Prevention found that adolescents who experienced a concussion in the past 12 months were 25% more likely to be in poor academic standing. This association was stronger with a history of repeated concussions, and varied by race/ethnicity.
A new analysis found that increased Medicaid dental payment policies were associated with modest improvements in children's dental visits. The study also showed a link between the payment rates and better oral health outcomes for kids.
A new study by a global team of researchers has revealed subtle alterations in the size of the brain's prefrontal region in young people with mood disorders and suicidal thoughts and behaviors. The study suggests that these associations may be absent or more difficult to identify in more diverse samples.
Researchers are developing a comprehensive surveillance system to track lingering symptoms of COVID-19, known as long COVID-19. They will utilize existing health data and enroll patients to gain accurate information on the burden and outcomes of individuals affected by long COVID.
A new method using machine learning corrects damaged DNA and unveils true mutation processes in tumour samples, helping early cancer detection and accurate diagnosis. The tool predicted over 90% of developing cancer processes, offering a significant advancement in cancer patient care.
A large primary care network analysis reveals that telephones and tablets are used most often for telehealth visits. Patients who were younger, Black or Hispanic or Latino, and living in lower-income zip codes had higher rates of telephone or tablet use.
A study published in NEJM found that individuals infected with previous SARS-CoV-2 variants have four times greater protection against the current Omicron BA.5 subvariant than those who were not infected. This hybrid immunity provides significant protection against future infections.
A new project led by University of Illinois researchers aims to empower librarians with a toolkit for creating data-driven stories. The initiative, backed by an $99,330 grant, will provide easy-to-use templates for visualizing and structuring data narratives.
The proposed CODE-EHR best practice framework aims to standardize the use of structured electronic healthcare records in clinical research. The framework focuses on identifying and addressing data quality issues, ensuring interoperability between systems, and promoting transparency and trust.
A nationwide study in Spain found that eating breakfast at home is linked with fewer behavioral problems in young people. The study suggests that skipping breakfast or eating away from home can lead to increased likelihood of psychosocial behavioral problems.