Articles tagged with Medical Diagnosis
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Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
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Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
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Researchers used a new fMRI analysis method to measure cerebrovascular reactivity in 53 adults aged 51-83. They found an unexpected improvement in brain health in postmenopausal female participants, primarily in areas related to movement and memory.
The National Center for Excellence in Primary Care Research (NCEPCR) consolidates primary care research under one roof, enhancing the nation's primary care system. NCEPCR aims to tackle critical challenges such as workforce shortages and rising healthcare costs by curating essential tools and cultivating researchers.
A new smartphone app, ECHAS, can help people determine if they are suffering from a heart attack or stroke and need medical attention. The app, developed by experts at UVA Health and other leading institutions, proved effective in identifying patients with cardiac and neurological emergencies.
Researchers have developed a machine learning tool that identifies metabolism-related molecular profile differences between colorectal cancer patients and healthy individuals. The tool, called PANDA, shows promise as a noninvasive method of diagnosing colorectal cancer and monitoring disease progression.
Researchers at Kyoto University have developed a new non-invasive diagnostic method for insulinomas, which achieved 100% diagnostic accuracy in a Phase II clinical trial. The new method using positron emission tomography (PET) probe successfully detected cases difficult to diagnose through existing methods.
Researchers have developed a 3D micro-printed sensor that uses whispering-gallery-mode microlasers to detect biomarkers with attogram per milliliter sensitivity. The sensors' unique Limacon-shaped design improves efficiency and enables on-chip integration, making them suitable for high-performance lab-on-a-chip devices.
A review of 151 studies found that symptom invalidation can cause emotional states like self-doubt and shame, as well as behavioral changes such as avoiding medical care. The study recommends that healthcare providers validate patients' experiences, even in cases where a clear diagnosis cannot be made.
This study reveals periostin as a superior serum biomarker for diagnosing idiopathic pulmonary fibrosis, with high sensitivity and specificity compared to traditional markers. Periostin levels also correlate with disease severity and predict acute exacerbations in IPF patients.
Researchers identified six risk groups for cardiometabolic complications in older people without type 2 diabetes, with a special high-risk group characterized by inflammation and insulin resistance. The study emphasizes the need for precise early detection and prevention strategies.
A modified surgical face mask can detect chronic kidney disease by analyzing the wearer's breath, showing high sensitivity for CKD-related metabolites. The sensor accurately identifies patients with CKD 84% of the time and those without 88% of the time.
Two new predictive algorithms use health data and blood tests to identify high-risk patients, offering improved accuracy in diagnosing cancers. The models identified additional medical conditions associated with increased cancer risk and new symptoms indicative of multiple cancer types.
A study published in JAMA Neurology found no evidence supporting a diagnosis of the New Brunswick neurological syndrome of unknown cause, highlighting the need for independent clinical evaluations. The data revealed presence of several neurodegenerative and non-neurodegenerative conditions instead
This study compares laser-guided technology to conventional manual percutaneous lung biopsy, finding that laser-guided technology can reduce operational time and needle adjustments. However, it did not reduce complication rates or improve pathological diagnosis accuracy compared to traditional methods.
A study published in The Lancet Regional Health – Europe found that patients with low household income were more likely to be diagnosed late and receive less effective treatment for liver cancer. This highlights the need for targeted screening in deprived areas to improve early diagnosis and survival rates.
A new study found that age-, sex-, and race-specific standards could reclassify many thyroid disease diagnoses, with nearly half of subclinical hypothyroid cases being over-diagnosed. The study suggests using these standards to establish more accurate reference intervals for thyroid disease.
Researchers from Université Laval discovered a non-invasive retinal exam can detect Parkinson's disease biomarkers, offering early diagnosis and potential intervention. The study found distinct retinal responses to light stimuli in people with Parkinson's compared to healthy individuals.
Researchers at the University of Utah have developed RiskPath, an Explainable AI toolkit that predicts disease progression years before symptoms manifest. The technology analyzes health data to identify high-risk individuals with unprecedented accuracy, offering new insights into risk factor interactions and disease development.
Researchers discovered how certain bacteria breathe by generating electricity, using a natural process that pushes electrons into their surroundings. This finding could enable new developments in clean energy and industrial biotechnology.
A new review advocates for building confidence in AI applications by implementing robust data governance frameworks, enhancing transparency, and involving stakeholders. The authors emphasize the importance of addressing ethical implications and ensuring equitable access to AI-driven innovations in clinical oncology.
Researchers at Karolinska Institutet have identified biomarkers in the blood associated with long COVID symptoms, particularly severe respiratory disorders. The study found that these biomarkers are also linked to inflammatory signal pathways involved in cell death and lung damage.
Researchers at Karolinska Institutet have identified new biomarkers in urine that can indicate the presence and severity of prostate cancer with high precision. The findings surpass current blood biomarker PSA in terms of diagnostic accuracy.
A misfolded protein in spinal fluid facilitates reliable Parkinson's diagnosis even in its early stages. The biomarker has a sensitivity and specificity of over 90%, making it a promising tool for disease management and potential therapy development.
The percentage of publicly insured children receiving mental health or neurodevelopmental disorder diagnosis increased significantly between 2010 and 2019. Most diagnostic categories showed increases, emphasizing the importance of accessing appropriate services in safety net systems.
Patients who develop epilepsy after a traumatic brain injury are at an increased risk of premature death, with a mortality rate 1.8 times higher than those without epilepsy. The study also found that the risk of developing epilepsy is highest in the first year after the injury.
Researchers at Tulane University identified a potential new way to treat idiopathic pulmonary fibrosis (IPF) using an FDA-approved cancer drug. The treatment works by blocking the CTLA4 protein, which blocks overactive T cells, allowing the immune system to clear out damaged cells that cause lung scarring.
Juvenile-onset recurrent respiratory papillomatosis (JORRP) is a rare disease causing chronic hoarseness and breathing difficulties in children. New clinical guidelines provide actionable recommendations for early recognition, diagnosis, and treatment to improve long-term outcomes.
A recent meta-analysis found that generative AI's diagnostic accuracy is lower than that of specialist doctors, with an average accuracy of 52.1%. The study suggests that while generative AI has the potential to support non-specialist doctors in diagnostics, further research is needed to improve its capabilities.
Researchers at the University of Missouri's Thompson Center for Autism and Neurodevelopment have found that behavior at 9 months old can indicate a 1-year-old's likelihood of being at risk for autism. Parent surveys reported fussiness, irritability, and difficulty calming down were associated with early signs of autism by 12 months.
Researchers at the University of Cambridge have developed a handheld device that can accurately record heart sounds without requiring precise placement on the chest. This innovative device, which uses six sensors to capture clearer heart sounds, has the potential to transform heart disease screening and diagnosis.
Living in disadvantaged neighborhoods is associated with a higher risk of mortality from breast cancer in Black women. Community-level interventions aimed at reducing environmental stressors and improving access to high-quality cancer care could help reduce racial disparities in breast cancer survival.
A study of nearly 30,000 adults found that heart failure is associated with a significant decrease in cognition at diagnosis and rapid decline over time. Adults with heart failure reach the threshold for meaningful decline in global cognition nearly six years earlier than those without it.
A team of chemists from Virginia Tech found a way to visualize the intricate structure and chemical reactions of battery interfaces using an X-ray beam line. This breakthrough enables researchers to gain better control over these critical surfaces, potentially leading to cheaper, higher performance batteries.
Three UVA Engineering faculty members, Scott T. Acton, Gustavo Kunde Rohde and Shannon Barker, have been named to the 2025 class of the American Institute for Medical and Biological Engineering (AIMBE) College of Fellows. They are recognized for their contributions to biomedical engineering research, innovation, teaching and leadership.
A new consensus paper emphasizes the role of bone turnover markers (BTMs) in diagnosing and managing osteoporosis. BTMs, such as procollagen type I N propeptide (PINP) and β-isomerized C-terminal telopeptide of type I collagen (β-CTX-I), are invaluable tools for predicting fracture risk and monitoring treatment adherence.
A new virtual reality-based system shows promise in improving psychiatric diagnosis by differentiating between common mental health conditions. The system uses immersive scenarios and physiological measurements to elicit emotional responses, suggesting enhanced diagnostic accuracy.
Researchers at Karolinska Institutet have developed a new method to diagnose COPD by analyzing protein levels in nasal lavage. The study found that elevated IL-26 levels can indicate an early phase of the disease, and may lead to new treatment strategies targeting this cytokine.
Researchers used a large language model to analyze clinical reports of autism patients and found that repetitive behaviors and special interests are most indicative of an autism diagnosis. The study aims to improve diagnostic guidelines by reducing the focus on social factors.
A new brief warns that assistive AI may worsen challenges related to error prevention and physician burnout. The researchers predict that medical liability will depend on who is considered at fault when the technology fails, subjecting physicians to unrealistic expectations.
A simple urine test has shown promising results in detecting early-stage kidney cancer recurrence, with a high sensitivity and specificity rate. The GAGome test can accurately identify patients at risk of recurrence, potentially reducing the need for invasive scans and enabling faster treatment access.
A new study has shown that high-resolution ultrasound can diagnose prostate cancer as effectively as MRI, with improved resolution and lower costs. The technology, called micro-ultrasound, is expected to speed up diagnosis, reduce hospital visits, and make imaging more accessible, particularly in less developed healthcare systems.
The Dexcom G7 CGM device demonstrated an accuracy of 8.0% in a study involving 130 adults with type 1 or type 2 diabetes, setting a new standard for continuous glucose monitoring devices.
The INHALE-3 extension study found that a regimen of inhaled technosphere insulin and insulin degludec reduced post-meal hyperglycemia in adults with type 1 diabetes. The treatment showed significant improvements in mean time in range, with 43% of participants expressing interest in continuing the regimen.
A new study shows that comprehensive clinical assessments (CCAs) are equally effective to guiding treatment for women with overactive bladder or urinary incontinence, avoiding invasive urodynamics testing. CCA includes a medical questionnaire, physical examination, and tests such as urinalysis, revealing similar patient-reported outcom...
A new study from the University of Surrey found that healthcare professionals face difficulties in recognizing and addressing disordered eating in people with type 1 Diabetes due to lack of support and limited confidence. This can lead to delays in diagnosis and potentially life-threatening complications for patients.
Patients from American Indian and Black communities are less likely to have elevated CA-125 levels at diagnosis, suggesting current thresholds may miss diverse patients. Inclusive diagnostic guidelines are needed to address disparities in ovarian cancer diagnosis and treatment.
A study of top 100 ADHD TikToks found that fewer than half of claims about ADHD symptoms aligned with clinical standards. Young adults' perceptions of the informational value of these videos differed from those of psychologists, leading to a potential spread of misinformation.
A new study by University of B.C. researchers found that ADHD-related content on TikTok often misrepresents the disorder and can lead to misunderstandings. The study highlights the need for mental health professionals to engage with social media platforms like TikTok to provide accurate information.
A multicenter cohort study found that higher adherence to annual lung cancer screening was associated with increased overall and early-stage lung cancer detection rates. However, adherence decreased over time, suggesting it is a critical quality metric for lung cancer screening.
A new study reports that Raman spectroscopy, a noninvasive technique, can distinguish between abnormal FCD type II tissue and healthy brain cells with remarkable accuracy. This method could provide real-time guidance for surgeons to more accurately identify and remove affected tissue during surgery.
The Shimadzu – DxD Hub Diagnomics Centre aims to accelerate the development of high-quality, cost-effective diagnostic solutions. It focuses on three key areas: infectious diseases, cancer, and metabolic disorders, with efforts to develop solutions for early disease detection and precision medicine approaches.
Research finds that certain viral antibodies and genetic risk factors can increase MS risk, with elevated antibody levels combined with a specific gene variant associated with strong increased risk. The study also identifies potential biomarkers for early diagnosis.
A recent study by Professor Mamas highlights the significant risk of cardiovascular diseases (CVD) in patients with cancer, particularly in aging populations. The review emphasizes the need for early diagnosis and regular monitoring to improve quality of life.
Breast and colorectal cancer screening rates have recovered from pandemic-related declines, surpassing pre-pandemic estimates. Cervical cancer screening rates remain below pre-pandemic levels, indicating a persistent trend of declining early-stage diagnoses.
A cross-sectional study of social media posts about popular medical tests found most posts were misleading or failed to mention important harms, including overdiagnosis. The data suggest a pressing need for regulation of misleading medical information on social media platforms.
The American College of Chest Physicians (CHEST) has developed an educational program and formal certification exam for nurse practitioners and physician assistants/associates in critical care. The program validates clinical expertise and demonstrates professional acumen, aiming to improve patient care.
A new study found that people from minority ethnic groups are more likely to report non-cognitive symptoms, such as pain and dizziness, before receiving a dementia diagnosis. This can lead to delays in diagnosis and impact health inequalities. The research aims to improve culturally fair recognition of possible dementia in primary care.
A new review of clinical trials found that single-session interventions can significantly improve mental health outcomes for both youth and adults, with 83% reporting positive effects. The approach is poised to fill gaps in the mental health care system, particularly for digital, self-guided therapies.
Amplified Sciences has received CLIA certification for its PanCystPro test, which helps risk stratify patients with pancreatic cystic lesions. The company plans to commercialize the test through an early access program and a clinical utility trial in 2025.
A new standard dataset defines 16 clinical and patient-reported outcome measures for adults with heart valve disease. The International Consortium for Health Outcomes Measurement (ICHOM) developed the globally inclusive standard dataset.
Implantable physical sensors monitor temperature, force, flow, and pressure to facilitate timely diagnosis and advanced health management. These sensors have the potential to revolutionize medical practices by enabling direct, real-time acquisition of critical physiological signals.