Research on how disease is diagnosed. Covers fetal-distress detection, faster diagnostics, redefining conditions, and bias in medical AI.
A new study suggests that sweat can reveal information about a person's health, including hormone levels, medication doses, and early detection of diseases like diabetes and cancer. Wearable sensors using artificial intelligence can detect specific metabolites in sweat, providing personalized health insights.
A new review emphasizes the importance of smell health, highlighting its role in nutrition, cognitive function, and psychological resilience. Researchers call for a global campaign to promote smell health through education, awareness, and targeted public health policies.
A study of seven outpatient facilities found that 20-24% of all breast cancers diagnosed between 2014 and 2024 were in women aged 18-49. Invasive cancer cases accounted for 80.7%, often with aggressive types, challenging age-based screening cutoffs.
The study found that GLP-1 receptor agonists are increasingly used for postpartum weight loss in overweight women without a documented diabetes diagnosis. The primary indication for use was weight reduction, suggesting a potential shift in treatment guidelines.
Researchers created AI model popEVE that can identify disease-causing mutations in human proteins, even for unique cases. It ranks mutation severity across the body, helps doctors focus on most damaging variants first.
A study at Technical University of Munich found that AI-simplified CT reports reduced reading time to two minutes and improved patient comprehension. Patients rated the simplified texts as more helpful and informative, with 82% finding them easier to read and understand.
A team of scientists at the University of Tokyo has developed an automated, high-throughput system that uses machine learning to analyze droplets of biofluids for disease diagnosis. The technology relies on imaging drying processes to distinguish between normal and abnormal samples.
Large language models can help improve psychological questionnaires by avoiding redundant items and making diagnosis more efficient. The study found that LLMs recognize common symptom associations and can be used to develop precise and efficient questionnaires.
A study by NTU Singapore researchers found that enlarged perivascular spaces, or 'clogged drains', in the brain are a likely early-warning sign of Alzheimer's disease. The condition can be visually identified on routine MRI scans, complementing existing methods to detect Alzheimer's earlier.
Researchers at The University of Osaka have developed a novel Balloon-Assisted Bronchoscope Delivery (BDBD) technique, enabling safe access to small, early-stage lung cancers hidden in the peripheral lung fields. This innovation promises to revolutionize both early diagnosis and minimally invasive treatment.
A new urine test can detect SORD deficiency, a common cause of inherited nerve disease, earlier and more cheaply than genetic tests. The test has brought understanding and access to care for affected families, particularly in the Old Order Amish community.
Researchers have developed an innovative antibody-based enzyme switch called 'Switchbody', which is activated upon antigen binding. The switch's mechanism relies on a 'trap-and-release' process, offering new opportunities in diagnostics and therapeutics.
Researchers are presenting groundbreaking findings at the Association for Molecular Pathology's annual meeting, including a novel technique to study ancient DNA and rapid detection of serious fungal pathogens. The Association for Molecular Pathology is providing press materials and resources for media coverage.
Artificial intelligence is being used to improve diagnostic accuracy in molecular pathology, with studies showing 93% accuracy for cancer diagnosis. Researchers are also using AI to analyze chromosomal changes in blood cancer patients and provide personalized treatment plans.
Researchers have developed a new molecular test to identify Lyme disease earlier and more accurately than traditional methods. The test can detect as few as five bacterial cells and has an estimated sensitivity of 90.9%, making it a potential new avenue for testing Lyme disease.
A deep learning system developed by Incheon National University integrates images and clinical details to improve early skin cancer diagnosis. The model achieved 94.5% accuracy, outperforming popular image-only models.
Researchers at UCSF used AI to analyze clinical notes from multiple providers to improve HRS diagnosis accuracy. The technology offers a unified summary of the care team's consensus, aligning care decisions and expediting treatment plans.
A new report from Northwestern University offers six practical strategies to improve the doctor-patient bedside encounter in an era dominated by AI. By employing these strategies, clinicians can strengthen patient-physician relationships, combat inequities, and reduce burnout, ultimately leading to better patient outcomes.
A recent FAU Engineering study leverages quantum computing to enhance the accuracy of chronic kidney disease (CKD) diagnosis. The research team developed and compared two automated systems: Classical Support Vector Machine (CSVM) and Quantum Support Vector Machine (QSVM). CSVM achieved remarkable 98.75% accuracy, while QSVM reached 87....
Australian scientists have developed a new blood test that can identify women with ovarian cancer more likely to benefit from PARP inhibitor therapy, offering hope for more effective treatment. The test measures immune biomarkers and predicts which patients will respond to treatment.
Researchers developed an AI model that outperforms radiologists in detecting hidden objects on chest scans, particularly for cases of foreign body aspiration. The model achieves high precision and recall rates, helping doctors diagnose complex conditions more reliably.
A review highlights transposable elements' influence on gene expression, genome stability, and disease development. TEs are recognized as regulators of gene regulation and disease, offering new avenues for diagnosis and therapy.
Researchers analyzed carotid plaque samples from 75 Chinese and 111 US patients, revealing distinct differences in plaque morphology, size, and composition. The study highlights the importance of understanding population-specific variations to develop personalized treatment approaches for cerebrovascular events.
A liquid biopsy test may enable early detection of various cancers, increasing stage I–III diagnoses by 10-30% and stage IV diagnoses by 45%. This could improve patient outcomes and reduce the economic impact of cancer. The study's findings suggest a game-changing approach to cancer control.
Research published in ERJ Open Research suggests that assessing hospital patients' reported shortness of breath could help doctors prioritize care for those at high risk of death. Patients who developed shortness of breath were six times more likely to die than those who did not, with a higher rating indicating greater risk.
A new study published in the Chinese Neurosurgical Journal explores an AI tool that identifies medulloblastoma subgroups based on magnetic resonance imaging scans. The model achieved impressive accuracy in predicting molecular subtypes and genetic risk factors, with 91% accuracy for TP53 mutations and 87% accuracy for chromosome 11 loss.
Researchers found that combining three biomarkers – lipoprotein(a), remnant cholesterol, and high-sensitivity C-reactive protein – can reveal a nearly three-fold increase in heart attack risk. This combination approach may aid health care professionals in identifying individuals with high-risk profiles earlier.
Researchers have developed an AI-driven facial recognition system called AcroFace that can detect acromegaly by analyzing facial photographs. The system achieved a success rate of 93% in a preliminary trial, outperforming previous attempts. Early detection could lead to timely treatment and improved outcomes for patients with this rare...
Researchers discovered that cardiac fibroblasts use a signaling pathway to promote harmful changes in the heart, weakening its ability to pump blood efficiently. Blocking this pathway in mice models improved heart function, suggesting that fibroblasts could be a potential target for new therapeutic strategies.
A new study suggests that collecting and testing cancer cells in patients' blood could help doctors choose the right breast cancer treatment. The 'labyrinth chip' technology separates cancer cells from other blood cells, allowing researchers to identify biomarkers that distinguish aggressive treatments from less invasive ones.
A new study reveals how prenatal alcohol exposure impairs key brain cells and circuits, leading to cognitive inflexibility and increased risk of compulsive alcohol use. Researchers identified a specific brain cell affected by early alcohol exposure, providing a clear target for developing more effective treatments of FASD.
A new Alliance trial is exploring the effectiveness of a combination of targeted therapy and immunotherapy for patients with advanced adrenocortical carcinoma, a rare and aggressive cancer. The study aims to improve disease control and quality of life for patients with limited treatment options.
Researchers at FAU Engineering have developed foot-mounted wearable sensors and a 3D depth camera that accurately measure how people walk, even in busy clinical environments. The study findings reveal that these technologies match the accuracy of traditional tools but are more scalable, remote, and cost-effective.
The Association for Molecular Pathology recognized Dr. Laposata's contributions to clinical laboratory practice and his role in challenging the FDA's rule on laboratory-developed test regulation. The award preserves diagnostic innovation, ensures patient access, and avoids escalating healthcare costs.
Tear-derived extracellular vesicles show promise as non-invasive biomarkers for ocular and neurodegenerative diseases. The study highlights their potential to provide valuable information about the eye's health, including processes related to neurodegenerative diseases.
Rebecca Richards-Kortum has been elected to the National Academy of Medicine for her major contributions to global health. She created low-cost, lifesaving technologies for underserved communities, transforming health systems worldwide through her innovations in cervical cancer diagnostics and neonatal care technologies.
A recent study found that cannabis may reduce opioid use among commercially insured patients with cancer diagnoses, indicating potential benefits for pain management. However, further research is needed to confirm the efficacy of cannabis as a treatment for cancer-related pain.
The Josep Carreras Institute is pioneering Spatial Transcriptomics to understand tumor structure at the cellular level. The institute's guidance on this methodology offers practical solutions for improving reproducibility and clinical application.
Researchers developed an ultra-sensitive hydrogel for human-machine interaction, achieving high-accuracy collaboration in remote surgical operations and virtual reality. The AirCell Hydrogel boasts a smooth surface and porous interior structure, allowing it to detect various human motions with exceptional accuracy.
A landmark study analyzed health data from over 600,000 patients across 10 countries to assess patient risk for non-ST-elevation acute coronary syndrome (NSTE-ACS). The AI-powered model GRACE 3.0 predicts risk more accurately and guides personalized treatment decisions.
Researchers have developed a non-invasive blood test that can detect Amyotrophic Lateral Sclerosis (ALS) earlier and with higher accuracy by measuring cell-free DNA. The test distinguishes between ALS patients and healthy individuals, as well as those with other neurological conditions.
Researchers introduced refinements to a rarely used surgical method, the reverse homodigital dorsoradial flap, for radial thumb defects. The key refinements preserved subcutaneous tissue for venous drainage and left a buffer zone at the arterial pivot point to reduce stress on blood vessels.
A cross-sectional study reveals substantial motor difficulties in preschool children that remain under-recognized by parents. The study supports timely referral to clinicians for formal diagnosis using a systematic approach for early identification in preschoolers. The findings highlight the need for structured screening and awareness ...
Scientists have developed a high-accuracy blood test to diagnose Chronic Fatigue Syndrome (ME/CFS), with 96% sensitivity and 98% specificity. The test uses EpiSwitch technology to identify unique DNA patterns in patients, offering new hope for diagnosis and treatment.
A study by researchers at the University of São Paulo identified high levels of neuroinflammation in young individuals with Down syndrome, contributing to the high prevalence of Alzheimer's disease. The discovery paves the way for disease prevention strategies and personalized treatments.
A new molecular sensor can detect influenza virus in the presence of a thymol flavor, which is released when the virus interacts with human saliva. Researchers plan to integrate this technology into chewing gum or lozenges for at-home screenings and pre-symptomatic transmission prevention.
A recent study suggests that the rise in early-onset cancer incidence in the US population may not be as significant as initially thought. Much of the increase is attributed to increased diagnostic scrutiny and over-diagnosis, rather than a genuine rise in clinically meaningful cancer cases.
A simple blood analysis can predict the risk of developing severe liver disease, enabling earlier detection and potentially improving treatment outcomes. The CORE model, developed by Karolinska Institutet researchers, is based on three routine blood tests and has been shown to be highly accurate in predicting liver disease risk.
Dr. Langlois and his team will support large-scale scientific research, protect vulnerable communities, and strengthen Canada's ability to face future health emergencies. The High-Throughput Facility infrastructure will rapidly detect and track new infectious disease threats while protecting people and communities.
A new robot-assisted bronchoscope has been shown to diagnose tiny lung tumors in hard-to-reach areas with over 84% success rate, more than three times higher than traditional methods. The technology enables accurate diagnosis in patients where conventional bronchoscopy offers no viable option.
Researchers discovered widespread inflammation, immune cell dysfunction, and cellular reprogramming in people at risk for RA. The study identified new biologic targets for prevention and ways to improve treatments.
Leading researchers are advocating for increased diagnostics and treatment of Alzheimer's disease, citing significant advances in research and the availability of new medicines. The European Union has approved two medicines that slow the progression of mild dementia by removing amyloid plaques from the brain.
The study introduced an Epic electronic health record workflow to auto-order preventive and chronic disease tests for complex older adults. This approach has improved patient engagement, reduced post-visit results communication, and minimized cancellations.
Researchers developed a flexible optical touch sensor that can pinpoint pressure strength and location with high sensitivity. The sensor uses multiple optical channels to detect pressure in more than one spot, enabling smart interfaces and devices.
Researchers developed an AI model that diagnoses achalasia using plain chest X-rays, outperforming physicians' reviews. The diagnostic performance of the AI model demonstrated higher sensitivity and specificity, enabling early diagnosis and potentially improving treatment efficacy.
A deep learning model achieved up to 98% accuracy in distinguishing autistic from neurotypical participants, providing clear insights into brain regions most influential to its decisions. The model could benefit autistic people and clinicians by offering accurate and explainable results to inform assessment and support.
Researchers at Salk Institute and UC San Diego have identified a unique sugar called HSAT as a potential therapeutic target for slowing tumor progression and metastasis in pancreatic ductal adenocarcinoma. Boosting HSAT levels may slow the formation and spread of pancreatic cancer, leading to improved survival rates among patients.
Researchers at Tulane University have developed an enhanced CRISPR-based tuberculosis test that works with a simple tongue swab, detecting TB in samples with very low levels of bacteria. The new test shows high sensitivity and accuracy, offering a significant step forward toward effective diagnoses via a variety of samples.
A new algorithm developed by Núria Malats and her team can accurately predict the presence of metastasis in pancreatic cancer using medical images. The PMPD algorithm has shown promising results, classifying 56% of metastases with high accuracy and potentially avoiding unnecessary surgeries.
The VasCog-2-WSO criteria update provide operationalization and guidance on neuroimaging and fluid biomarkers for VCID diagnosis. This new standard aims to facilitate diagnostic consistency among clinicians and researchers worldwide.