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Understanding arteriosclerosis: How blood vessels restructure under pressure

High blood pressure can cause long-lasting changes in the structure of vascular smooth muscle cells, stiffening arterial walls and increasing the risk of cerebrovascular disease. Researchers found that a signaling pathway triggered by E–T coupling is involved in this process, leading to inflammation and vascular remodeling.

SourceNagoya City University·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateApr 22, 2022

Electronic implant reactivates spinal-cord nerves of a patient with neurodegenerative disease

A groundbreaking system implanted directly on the spinal cord has restored blood pressure regulation in a patient with multiple system atrophy-parkinsonian type (MSA-P), enabling them to walk again after being bedridden for over a year. This innovative therapy paves the way for new clinical breakthroughs in treating degenerative diseases.

SourceEcole Polytechnique Fédérale de Lausanne·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateApr 6, 2022

Under (blood) pressure

A study by Alisa Auer and Petra Wirtz found that men with essential hypertension are more likely to recognize angry expressions when looking at others' faces. This 'anger recognition bias' contributes to increased blood pressure over time if someone experiences high levels of anger.

SourceUniversity of Konstanz·JournalAnnals of Behavioral Medicine·DateMar 31, 2022

U of M researchers finds that losartan is not effective in reducing COVID-19 lung injuries

A study published in JAMA Network Open found that losartan treatment did not reduce lung injury in patients admitted with COVID-19, but may be needed for blood pressure support. Researchers emphasize the need for repurposing inexpensive medications to contain healthcare costs.

SourceUniversity of Minnesota Medical School·JournalJAMA Network Open·TypeRandomized controlled/clinical trial·DateMar 16, 2022

Even mild or moderate COVID-19 can affect the cardiovascular system in young adults, study shows

Researchers found that post-COVID patients displayed altered autonomic nervous system functioning, with increased sympathetic activity and decreased parasympathetic activity. Obesity and physical inactivity were key factors contributing to these changes.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalInternational Journal of Environmental Research and Public Health·DateMar 15, 2022

Could a community-based approach to genetic testing help African Americans reduce risks of chronic kidney disease?

Researchers found that a community-based approach to reporting APOL1 genetic test results resulted in lower blood pressure readings among hypertensive patients. This trial suggests that involving communities in genetic testing could be beneficial for reducing the risks of chronic kidney disease.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalJAMA Network Open·TypeRandomized controlled/clinical trial·DateMar 4, 2022

Is blood pressure reading more accurate at home or clinic?

A new study led by Kaiser Permanente investigators found that home blood pressure monitoring is a better option for making new diagnoses of hypertension than clinic settings. This method allows for multiple readings to be collected and averaged, providing a more accurate representation of an individual's average blood pressure.

SourceKaiser Permanente·JournalJournal of General Internal Medicine·DateMar 3, 2022

New research advances wearable medical sensors

Researchers have developed wearable sensors that collect data for clinicians while limiting patient discomfort. The sensors use flexible electronics to monitor patients' physical motions and chemical signals in their sweat, skin, and more to help diagnose or inform treatment plans.

SourcePenn State·JournalApplied Physics Reviews·DateMar 1, 2022

Salt in soluble paracetamol linked to increase risk of cardiovascular disease and death

A large study found a significant link between salt-containing paracetamol and an increased risk of heart attacks, stroke, and death. Patients with high blood pressure who took sodium-containing paracetamol had a higher risk of cardiovascular disease and death compared to those taking non-sodium-containing paracetamol.

SourceEuropean Society of Cardiology·JournalEuropean Heart Journal·TypeObservational study·DateFeb 23, 2022

Feeling dizzy when you stand up? Simple muscle techniques can effectively manage symptoms of initial orthostatic hypotension

Researchers discovered two simple physical maneuvers to effectively reduce blood pressure drops and alleviate symptoms of IOH in young women. Lower body muscle preactivation (thighs) and tensing improved cardiac output and stroke volume, respectively, leading to a reduction in symptoms upon standing.

SourceElsevier·JournalHeart Rhythm·TypeExperimental study·DateFeb 9, 2022

Mild autonomous cortisol secretion predominantly affects women, associated with risk for hypertension, diabetes

A cross-sectional study found that mild autonomous cortisol secretion (MACS) predominantly affects women, increasing the frequency and severity of hypertension and type 2 diabetes compared to nonfunctioning adrenal tumors. Patients with MACS carried an increased cardiometabolic burden similar to Cushing Syndrome, even without typical f...

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeObservational study·DateJan 3, 2022

Common drugs affect our gut microbiome differently, with good and bad impacts on health

Research shows that common medicines have distinct effects on gut bacteria, with some having beneficial and others detrimental impacts. The study found associations between certain medications and changes to the gut microbiome, particularly with statins and gastric acid medication.

Disparities in blood pressure control

A study of 16,000 adults with high blood pressure found significant racial disparities in blood pressure control, linked to unequal treatment intensification and missed appointments. The research highlights the need for targeted interventions to address these inequities and improve outcomes for underserved populations.

SourceJAMA Network·JournalJAMA Cardiology·DateDec 8, 2021

Sharrief awarded $3.1 million NIH grant to test whether telehealth improves racial disparities in outcomes for stroke survivors

A $3.1 million NIH grant will fund a trial testing multidisciplinary telehealth intervention to reduce racial disparities in blood pressure control and stroke recurrence among adult stroke survivors. The study aims to identify social determinants of health that impact outcomes and explore ways to address them.

Adding herbs and spices to meals may help lower blood pressure

A study found that consuming high amounts of herbs and spices daily can lead to significant reductions in systolic and diastolic blood pressure. The researchers discovered that adding just 1.3 teaspoons of herbs and spices a day to an average American diet resulted in lower blood pressure after four weeks.

SourcePenn State·JournalAmerican Journal of Clinical Nutrition·TypeRandomized controlled/clinical trial·DateNov 8, 2021

U-M Apple Watch Study provides an unprecedented look at the health status of a diverse patient population

The MIPACT study analyzed data from thousands of participants, revealing differences in heart rate, blood pressure, and activity levels by age, race, ethnicity, and clinical conditions. The study's findings have significant implications for clinicians, providing a more complete picture of daily life and resulting health.

SourceMichigan Medicine - University of Michigan·JournalThe Lancet Digital Health·DateOct 26, 2021

Is low-fat or whole-fat milk better for kids? Science says it makes no difference

A recent study published in the American Journal of Clinical Nutrition found that consuming whole fat milk has no negative impact on children's health. The research, which involved 49 healthy children aged four to six, showed that both groups consumed similar amounts of calories and fat.

SourceEdith Cowan University·JournalAmerican Journal of Clinical Nutrition·TypeRandomized controlled/clinical trial·DateOct 11, 2021