Researchers from Florida Atlantic University advise against prescribing ivermectin to treat or prevent COVID-19 due to the lack of reliable evidence. They emphasize the importance of relying on proven therapeutic innovations and vaccinations to combat the pandemic, citing the risks of unproven treatments like ivermectin.
A Harvard T.H. Chan School of Public Health study suggests that US elementary schools should only remove masks when local COVID-19 case rates are below a certain threshold to avoid increased transmission. The study provides a framework for school decision-makers to estimate the level of mitigation needed to meet their goals.
A small study found statistically significant improvements in various symptoms, including fatigue and chest discomfort, after EECP therapy in long COVID patients. Researchers believe this is the most plausible explanation for the benefits derived from EECP and its link to long COVID.
A recent study published in the Journal of Wildlife Management found that vulture declines are linked to increased disease risks due to their absence. With no natural clean-up crew, diseases spread rapidly among scavenger communities, including feral dogs, which fill the ecological gap left by vultures.
Research reveals that approximately 3 out of 4 Fusarium infections of northern Vietnamese bananas are caused by F. tardichlamydosporum and F. odoratissimum, with wild bananas potentially acting as a sink for the disease. The study's findings suggest that concrete measures can be taken to control the future spreading of the disease.
Researchers have discovered a spray-induced gene silencing technique that effectively controls late blight, a devastating disease affecting potatoes and tomatoes. This environmentally friendly method has potential to reduce the usage of chemical pesticides and can be quickly adapted for new targets.
A new study found that one dose of ivermectin was just as effective as two doses in reducing scabies prevalence and impetigo cases. The 'screen-and-treat' approach using permethrin cream was also effective, but impractical for large-scale implementation.
Research suggests a possible silver lining for great ape conservation: a decline in respiratory illnesses among wild mountain gorillas in Rwanda since the COVID-19 pandemic began. The reduced number of outbreaks correlates with decreased human-gorilla proximity and additional health measures.
A new study found that rural counties had 2.4 times more infections per 100,000 people than urban areas during the third wave of COVID-19 in summer 2021, driven primarily by the delta variant. Low-vaccination areas experienced a more intense surge of new cases.
A new study finds that immune cells clear away a key Alzheimer's disease protein on an oscillating daily cycle controlled by circadian rhythms. The discovery provides a potential mechanism linking Alzheimer's disease to disruptions in sleep cycles and may lead to the development of chronotherapeutics.
A national study found that states with higher labor underutilization, non-Hispanic white populations, and opioid prescriptions had higher SIM rates. States with centralized medicolegal death investigation systems detected more SIM cases due to toxicologic testing.
Researchers developed a new reagent-free detection technique for SARS-CoV-2 using Raman spectroscopy and machine learning. The method shows an accuracy of 80% in detecting COVID-19 infections from saliva samples, overcoming limitations of RT-PCR testing.
A new study suggests that preventing pandemics could save around 1.6 million lives and reduce mortality costs by $10 trillion annually by investing just 5% of the estimated annual economic losses associated with human deaths from COVID into environmental protection and early-stage disease surveillance.
Researchers detect four cryptic variants of SARS-CoV-2 in NYC wastewater samples, suggesting possible animal origins. The variants' mutations could help identify the next variant of concern for COVID-19.
A 22-year study in Tanzania found that children who slept under bed nets at an early age had a 40% higher survival rate compared to those who didn't. The study tracked over 6,700 children and provided unique insights into the long-term benefits of malaria control in young children.
The Purdue Research Foundation Office of Technology Commercialization has awarded more than $143,000 to three projects led by researchers in the College of Agriculture, Engineering and Veterinary Medicine. Guri Johal is developing a corn variant that could impact worldwide corn production with Trask funds supporting his project on clon...
The opioid crisis in the US has reached epidemic levels, with over 100,000 drug overdose deaths reported for the first time. The US Centers for Disease Control and Prevention attributes the rise to abuse of synthetic opioid fentanyl and the COVID-19 pandemic.
Research shows that mask mandates are effective in reducing COVID-19 transmission in rural US counties with lower population density. The study found a 16.9% reduction in cases after mask mandates were introduced.
A trial found that parents bought fewer sugary drinks when products displayed pictorial warnings about type 2 diabetes or heart damage. Pictorial warnings are being explored as a strategy to reduce children's intake of sugary drinks and related health outcomes.
SourcePLOS·JournalPLOS Medicine·TypeRandomized controlled/clinical trial·DateFeb 1, 2022
Researchers have discovered that a small protein called glucagon-like peptide-1 (GLP-1) couples the body's control of blood sugar and blood pressure. This finding could lead to new treatment strategies for patients with hypertension and/or diabetes.
A new genomics study has helped guide the development of vaccines against Shigella, a leading cause of severe diarrhoea in children. The research revealed the extent of genomic diversity among Shigella species, highlighting challenges to current vaccine approaches.
A new meta-analysis of available literature on ALS disease has identified a group of seven environmental chemicals as correlates with increased risk of developing ALS. Exposure to these chemicals, including BMAA and heavy metals, may be contributing to the disease burden in certain regions.
Researchers at UC Riverside have identified a new host protein interaction in chickens that triggers a strong immune response against viral infections. The discovery sheds light on the differences between bird and human immune responses to zoonotic viruses.
Researchers at TTUHSC developed novel hydrophilic nanoparticles that target bacterial membranes, killing pathogens while sparing mammalian cells. The nanoantibiotics' size-dependent activity reveals a new blueprint for developing non-toxic and environmentally friendly antibiotics.
A study of over 800 hospitals found that people experiencing incarceration or homelessness had increased COVID-19 hospitalization rates and longer hospital stays compared to the general population. This highlights the vulnerable status of these groups during the pandemic.
A new study from USC researchers sheds light on COVID-19 vaccine inequities in California, revealing disparities in vaccination rates among vulnerable populations. The study suggests that targeted community outreach and improved vaccine access can help reduce these disparities.
Researchers found that male mosquitoes beat their wings up to 500-1,000 times a second, changing frequency to produce 'distortion tones' more audible to the male ear. This change is partly due to their circadian clock and allows males to detect females in swarms.
A state-wide Massachusetts infection control program, implemented in 360 nursing homes, reduced COVID-19 infections among vulnerable residents, including those with dementia. Cohorting residents and proper adherence to infection control guidelines were key factors in this reduction.
Researchers at Waseda University discovered a new protein isoform called Senp5S, which helps regulate Drp1 and mitochondrial dynamics during brain development. The study suggests a novel and vital role for post-translational SUMOylation in neuronal differentiation.
Researchers at the University of Illinois Chicago have developed a new method for analyzing pyroptosis, a process of cell death previously thought to be irreversible. By using optogenetic gasdermin, they found that certain conditions can trigger pores to close within tens of seconds, suggesting the process dynamically self-regulates.
A study published in PNAS reveals that dengue-infected mosquitoes are more attracted to mammals and bite more often, increasing disease transmission chances. The research found that infected mosquitoes have difficulty locating blood vessels for feeding, leading to increased biting attempts and transmission events.
Researchers have found COVID-19 infection in white-tailed deer in six northeast Ohio locations, suggesting the virus may be spreading among wildlife. The study's findings indicate that infected deer can potentially harbor new strains of SARS-CoV-2, complicating human mitigation and control plans.
Scientists have discovered a novel way to combine two species of grass-like plants using embryonic tissue from their seeds, offering disease resistance and stress tolerance. The breakthrough technique allows for the addition of beneficial traits to monocotyledonous crops without genetic modification or lengthy breeding programmes.
Research reveals a lag of 5-10 years between reduced fungicide use and decrease in fungicide-resistant pathogens. The study's findings provide insights into the impact of fungicide resistance on global distributions of pathogens.
The CDC found flaws in the assay design and contamination of one component, leading to false positive reactivity in negative controls. A redesign and improved quality control measures have since been implemented.
A new study from the University of Georgia found that overweight youth are developing signs of artery stiffness, a significant risk factor for cardiovascular disease. Researchers measured visceral fat levels and arterial stiffness in over 600 children, adolescents, and young adults, revealing higher levels of visceral fat and arterial ...
A new NIH-funded study aims to test a program using a pharmacist-community health worker team to help patients with high blood pressure stay on track with their medication. The intervention addresses barriers to adherence, such as low health literacy and limited transportation access, through culturally relevant education and support.
A Phase 2 clinical trial showed sotorasib can shrink tumors and achieve disease control in heavily pretreated patients with advanced colorectal cancer. The study results exceeded the historic benefits linked to approved therapies, offering new hope for a population with limited treatment options.
Researchers found that in 2020, 93% of Guinea worms detected worldwide were in dogs in Chad. Dogs eating infected fish carry the parasite larvae, which means they maintain the life-cycle and humans can still catch the disease.
A study published in CMAJ found that hospital health care workers in Quebec had high seroprevalence of SARS-CoV-2 antibodies after the first wave of the COVID-19 pandemic. The highest rates were reported in hospitals with outbreaks, particularly those from older facilities.
A new study found that Omicron's immune-evading capabilities are significant, but some vaccinated and previously infected individuals have 'stronger' protection. However, the protection from Omicron may be compromised over time.
A new study links the composition of gut microbiome before infection to HIV susceptibility and progression. Men who contracted HIV in the early days of the pandemic had a greater relative abundance of pro-inflammatory vs. anti-inflammatory gut microbes, which contributed to their increased risk of developing AIDS.
The Liberty Asthma VOYAGE trial found that dupilumab significantly reduced the rate of severe exacerbations by nearly 60% and improved lung function and asthma control in children ages 6 to 11. Dupilumab was also shown to be safe, with minimal adverse reactions.
Researchers created a disease map of genes involved in eye disorders, shedding light on how individual cells respond to external factors like injury. The study paves the way for regenerative medicine and cell replacement therapies for eye diseases.
Researchers at USC developed a new peptide that stimulates the host's immune response to fight bacterial infections, offering an alternative to antibiotics. The peptide, MTD12813, is highly effective in clearing infections and modulates inflammation, reducing the risk of complications.
Researchers have discovered that certain microbes can prevent Clostridioides difficile infection by consuming nutrients essential for its growth. This new understanding challenges existing approaches to probiotic treatment options, which focus on restoring secondary bile acids.
The study found that indoor bars, private parties, and nightclubs were high-risk places for transmitting the Delta variant, with men being more susceptible. Previous infection conferred a 95% protective effect, while two doses of mRNA vaccines provided 67% protection against symptomatic infection.
Researchers from Trinity College Dublin investigate the epidemiology and population biology of Enteroccocus faecium, a high-priority pathogen. They found that Irish isolates have evolved independently and are diverse, with a unique genetic transposon element encoding vancomycin resistance.
Researchers have discovered that certain strains of Aspergillus can be used to degrade aflatoxins in crops, reducing the risk of food contamination. This biological control method utilizing biocontrol products is currently the most effective way to produce safe and healthy foods and feeds.
A recent study estimates that COVID-19 vaccination prevented almost 470,000 deaths among people aged 60 years and older across Europe. The authors found that early implementation of vaccination was associated with the largest reduction in expected deaths.
A systematic literature review found HIV seroprevalence in five key populations: men who have sex with men (MSM), people who inject drugs (PWID), prisoners, sex workers, and transgender people. The review identified significant gaps in data, particularly for transgender individuals.
A team of University of Pennsylvania biologists used citizen science data to create a comprehensive abundance map of the black-legged tick, responsible for transmitting Lyme disease. By correcting biases in the data, they were able to increase its value and provide insights into tick distribution across the Northeast US.
Researchers at University of Technology Sydney identified microRNA-21 as a potential therapeutic target for chronic obstructive pulmonary disease (COPD). Inhibition of microRNA-21 using antagomir-21 reduced inflammation and improved lung capacity in experimental models.
A study by Weill Cornell Medicine investigators found that antibodies secreted in the gut help control pathogenic forms of gut fungi like Candida albicans. However, patients with Crohn's disease often have impaired antibody function, leading to an overgrowth of harmful fungi.
A real-world study of BBV152 found that two doses resulted in 50% effectiveness against symptomatic COVID-19 in hospital workers. The study's findings support the importance of a second dose for maximum protection, but highlight limitations in estimating vaccine effectiveness against severe outcomes.
UC San Diego researchers developed a computer model to understand how viruses travel through the air, shedding new light on airborne COVID-19 transmission. The model simulates aerosol behavior and helps explain why SARS-CoV-2 is highly transmissible through the air.
A University of South Florida Health-led team discovered a lead candidate that selectively relaxes airway smooth muscle cells with no detectable drug desensitization. The biased beta-agonist, C1-S, offers a therapeutic option for asthma and obstructive lung diseases without the rapid loss of effectiveness seen with traditional β-agonists.
A recent study has identified 18 species of the fungus associated with olive tree anthracnose, including the most widespread in Spain, Greece, Tunisia, Portugal, and California. The research found significant differences in virulence among species and geographic regions, paving the way for more effective control methods.
Researchers at UConn Health have discovered that eliminating senescent cells in human fat tissue can alleviate signs of diabetes and improve insulin sensitivity. The study suggests that clearing away these dysfunctional cells could lead to game-changing new treatments for Type 2 diabetes.
Scientists at the University of Nottingham found a plant-based antiviral treatment to be effective in blocking the highly infectious SARS-CoV-2 Delta variant. The novel natural antiviral drug, thapsigargin, was shown to trigger a broad-spectrum host-centred antiviral innate immune response against all variants of the virus.