Articles tagged with Neurosurgery
A multidisciplinary team of experts developed a new dual-target DBS approach targeting two distinct brain regions to simultaneously treat OCD and TS. This approach allowed for optimal and sustained improvement in severe symptoms, providing hope for treatment-resistant patients.
WVU engineers developed a new electrode cuff called MouseFlex to test electric current treatments, overcoming previous challenges with stability and durability. The device can withstand high electrical stimulation and may benefit patients with conditions like rheumatoid arthritis and drug-resistant epilepsy.
Researchers at Nagoya University found that localized IDH wild-type histologically diffuse astrocytomas have a poor prognosis similar to the most malignant types of brain and spinal cord tumors. This highlights the importance of proper clinical diagnosis and treatment for patients with gliomas.
Researchers developed an AI-based diagnostic screening system called DeepGlioma to analyze tumor specimens and detect genetic mutations rapidly. The system identified molecular subgroups with high accuracy and has the potential to improve access and speed of diagnosis for patients with deadly brain tumors.
Researchers have developed a new technique that combines real-time images with short-wave infrared light to differentiate between cancerous tumours and healthy tissue. This innovation has the potential to improve treatment outcomes for neuroblastoma patients by allowing surgeons to remove cancerous cells more precisely.
Researchers discovered that lipid deposition on medical implant surfaces can signal to the immune system whether to attack or ignore the implant. This knowledge could help develop biomaterials that deflect host immune aggression, reducing malfunction rates for devices like pacemakers and surgical mesh.
Researchers at UTHealth Houston received $15 million in NIH BRAIN grants to study brain processes related to speech, epilepsy, and reading. A new minimally invasive device will be developed to record brain activity during speech, while another project aims to disrupt seizures using neuromodulation.
A patient with Parkinson's disease has received a pioneering stem cell-based transplant at Skåne University Hospital in Sweden. The procedure aims to replace lost dopamine nerve cells and is part of a clinical trial testing the safety and efficacy of this innovative treatment, which could potentially help millions of people worldwide.
A study published in PLOS ONE reveals that two elite brothers from Late Bronze Megiddo, Israel, had access to trephination, a rare brain surgery procedure, around 1500 BC. The brothers' tomb contained evidence of chronic disease and advanced bone lesions, suggesting they survived due to their wealth and status.
Researchers developed a new device to identify key membrane proteins in urine indicative of brain tumors. This could lead to early detection and increased survival rates for patients.
A 20-year study reveals that recent advances in surgical and clinical care have significantly reduced brain injuries in babies with congenital heart disease. Infants who received higher postoperative blood pressure had a 20% lower risk of brain injury compared to those in earlier stages.
Researchers found that spinal cord stimulation improved insomnia severity index and Epworth sleepiness scale scores by at least 30% in 39.1% and 28.1% of participants, respectively. The study also established minimally clinical important difference values to gauge treatment success.
Researchers at the University of Oklahoma are designing a customized device to better treat unique brain aneurysms. The device uses advanced biomedical 3-D printing to tailor the treatment to the specific shape, size, and location of each aneurysm.
A personalized brain modeling approach is being tested in a large-scale clinical trial for drug-resistant epilepsy, aiming to improve surgery preparation and patient specificity. The technique uses virtual models of patients' brains to simulate abnormal activity during seizures, helping clinicians identify target areas more effectively.
Researchers at the Queensland Brain Institute developed a new ultrafast fMRI technique to study brain activity. The technique revealed that brain activity follows preferential circuits depending on cell type organisation, and blood signals can reflect network organisation and cell type distribution.
Researchers found that patients diagnosed with behavioral-variant frontotemporal dementia may have a cerebrospinal fluid leak, which can be treated. The study discovered CSF-venous fistulas in nine patients, who had their symptoms reversed after surgical closure.
A nationwide registry of AVM patients from 52 hospitals in mainland China investigated the efficacy of different treatments on patient groups. The study found that categorizing treatment strategies based on disease severity is an ideal approach, and a multidisciplinary comprehensive assessment promotes individualized treatment protocols.
Researchers tracked 392 patients with diffuse low-grade glioma over 20 years and found that aggressive surgical removal offered a distinct survival advantage. Smaller tumor sizes were associated with longer survival times, highlighting the importance of early intervention.
Researchers found that Black patients were more likely to be recommended against surgical removal of their brain tumors, regardless of tumor size or socioeconomic status. The study provides a basis for future research on racial bias in clinical decision-making and its impact on patient outcomes.
A study published in the Journal of Dentistry found that patients with unexplained brain abscesses were three times more likely to have oral bacteria present. The researchers also discovered significantly higher counts of Streptococcus anginosus, a bacterium linked to dental abscesses and infections in internal organs.
A study by HSE researchers found that only the left inferior frontal gyrus is critically involved in action naming, which could help preserve speech in patients after brain surgery. The study used fMRI and rTMS to stimulate the brain and found that stimulating this region led to more accurate action naming.
A study published in Annals of Neurology found that patients with severe epilepsy who undergo surgical tissue analysis are at risk for rare secondary diseases, including inflammation and incipient Alzheimer's dementia-like. These conditions can lead to unexpected cognitive decline months or years after surgery.
Researchers at the University of Gothenburg found that using warmer brain irrigation fluid can halve the number of repeat operations needed to remedy bleeding under the cranium. This method involves replacing room temperature irrigation fluid with body temperature fluid, resulting in a significant reduction in surgical interventions.
A nationwide study found that hundreds of residents in neurological surgery trained on a first-of-its-kind simulator, mirroring real-life catastrophe scenarios. The simulation model was deemed feasible and cost-effective, similar to pre-flight simulators used by pilots.
The DiaQNOS project aims to develop quantum sensors for improved brain tumor surgery. Magnetic field sensors will refine neuronavigation, enabling more precise incision paths. Researchers from Mainz University and partners will create a device suitable for use in surgery.
A five-year review of focused ultrasound treatment for essential tremor found that patients experienced significant reductions in tremor symptoms, with benefits lasting long-term and no reported progressive or delayed complications. The study represents the largest long-term assessment yet conducted on the procedure.
Researchers used monoclonal antibodies to suppress the immune system in mice, tracking human neural stem cell survival using luciferase. The study reveals that monoclonal antibody-mediated immunosuppression enabled long-term survival of transplanted human neural stem cells in mouse brains for at least six to eight months.
A recent study presented at the American Heart Association's Resuscitation Science Symposium 2022 found that ICU evaluations prior to cardiac arrest improved survival rates by 15% among Black adults. This study analyzed data from over 28,000 adults who experienced cardiac arrest between 2000 and 2021.
Research found a hospital code response team arrives at least one minute quicker and leads to better patient outcomes with smartphone emergency code notification systems. The study used a secure texting system that connected with electronic medical records, reducing conventional methods' average delay of 78 seconds.
Researchers found that individuals who underwent hemispherectomy surgery at a young age can still recognize differences between pairs of words or faces with remarkable accuracy. The study, published in PNAS, sheds light on brain plasticity and its limitations.
Developing a new technology for preventing catheter obstructions in patients with hydrocephaly has been successfully demonstrated in a European project. Concentrating ultrasound waves can detach materials from the inside of shunts implanted in the brains of patients, enabling preventive cleaning without affecting other areas.
Researchers have developed an RNA-based editing tool that targets individual cells, enabling precise modification of cell functions to manage diseases. The tool uses the ADAR enzyme to selectively add proteins of interest, offering endless potential applications across the animal kingdom.
Research has found that former Scottish international rugby union players are at a significantly increased risk of developing neurodegenerative diseases, including dementia and motor neurone disease. The study's findings suggest that strategies to reduce head impact and traumatic brain injury in all sports are necessary.
Researchers from Xi'an Jiaotong-Liverpool University found that brain stimulation combined with a nose spray containing nanoparticles can improve recovery after ischemic stroke. The treatment increased cognitive and motor functions, and weighed more quickly than those treated with TMS alone.
A pilot clinical trial found that implanted brain-stimulating devices dramatically reduced bingeing episodes and helped patients lose weight in two patients with loss-of-control binge eating disorder. The study used a device to monitor activity in the nucleus accumbens, a brain region involved in processing pleasure and reward.
A new neurosurgical procedure has been deemed safe for measuring dopamine and serotonin in the human brain. The study, published in PLOS One, found no significant increase in infection rates among patients who underwent the procedure.
A new AI algorithm has been developed to detect subtle brain abnormalities causing epileptic seizures. The Multicentre Epilepsy Lesion Detection project used over 1,000 patient MRI scans to train the algorithm, which was able to detect focal cortical dysplasia (FCD) in 67% of cases. This could lead to more patients being considered for...
Researchers at Cedars-Sinai created complex computer models of individual brain cells using artificial intelligence. These models capture the electrical signals that neurons fire to communicate with each other, allowing researchers to replicate brain activity at the single-cell level.
Scientists have identified two areas of the auditory cortex specialized to recognize human voice sounds without linguistic meaning. These regions help react to sound cues allowing people to identify characteristics of the person speaking, such as gender, age, and height. This discovery sheds light on neurological disorders affecting vo...
A new AI-based dynamic brain imaging technology has been introduced by Carnegie Mellon University, which can map out rapidly changing electrical activity in the brain with high precision and speed. The technology uses deep learning approaches to translate scalp EEG signals back to neural circuit activity without human intervention.
A multicenter prospective study shows that 88% of isolated LCH skull lesions in children resolve spontaneously without surgery. The study supports a nonsurgical approach, avoiding the risks associated with removal.
A study by Michigan Medicine researchers has identified oncostreams, highly active cells connected to brain tumor growth and invasion. The team found that eliminating Collagen 1 production from tumor cells reduces tumor aggressive behavior. This discovery could lead to novel therapeutic targets for treating lethal brain tumors.
A new minimally invasive surgical approach uses spring-mediated cranioplasty and distraction osteogenesis to guide skull shape in infants with complex craniosynostosis. This technique enables normal brain development while improving head shape, with significant improvement seen in a 3-month-old girl with a complex form of the condition.
A meta-analysis published in The Lancet Oncology suggests that targeted radiation therapy, which spares healthy brain tissue, is equitable to whole brain radiation therapy for patients with small cell lung cancer and brain metastases. This approach may improve their care experience with fewer negative cognitive consequences.
A novel network analysis technology can pinpoint seizure originating brain regions and predict a patient's seizure outcome before surgery, using only 10 minutes of resting state recordings.
A study found that certain shunts used after epilepsy surgery may increase the risk of chronic headaches by causing the brain to shift across the skull. Researchers discovered that non-programmable shunt valves were associated with elevated brain shift, while programmable valves weren't.
Researchers at Cedars-Sinai discovered how the brain uses a group of neurons in the frontal lobe to monitor performance, enabling humans to learn from mistakes and develop specific skills. This mechanism allows for flexibility in learning new tasks and adjusting focus based on conflict or difficulty encountered.
A new study suggests that up to 1 in 4 cases of congenital hydrocephalus may be linked to genetic mutations affecting neural stem cell growth, leading to underdeveloped brains and enlarged ventricles. This paradigm shift could lead to targeted therapies such as gene editing or drugs to optimize neurodevelopment.
Researchers created patient-derived models of brain metastases that recapitulate human disseminated disease, reflecting clinical manifestations and biological characteristics. These models can be used to test therapeutic value of different treatments and explore new approaches tailored to each patient.
A team of researchers developed a prognostic model using automated brain scans and machine learning to predict survival and recovery in severe TBI patients. The model accurately predicted risk of death and unfavorable outcomes at six months after the injury, potentially improving clinical decision-making and patient care.
Researchers develop technique to improve ACDF by testing variable angle screws, reducing risk of micro motion and subsidence. The cage-screw combination model shows promising potential for increased stiffness and reduced clinical failure.
Researchers tracked brain cell activity in zebrafish during seizures, finding that seizures arise from an excess of excitatory over inhibitory neuron activity in confined regions. The findings suggest a nuanced role for both excitation and inhibition in seizure origins.
A study from the University of Pittsburgh found that methionine restriction can slow down the growth of difficult-to-treat brain tumors in children, known as diffuse midline gliomas. The researchers discovered that these tumors are uniquely dependent on methionine, an amino acid, and that depleting it can repress cancer cell growth.
A new robotic system allows surgeons to remotely treat patients experiencing a stroke or aneurysm, providing teleoperated endovascular treatment during the critical golden hour. With just one hour of training, neurosurgeons can successfully operate the system to guide a wire through complex vessels and reach difficult-to-reach areas.
A groundbreaking system implanted directly on the spinal cord has restored blood pressure regulation in a patient with multiple system atrophy-parkinsonian type (MSA-P), enabling them to walk again after being bedridden for over a year. This innovative therapy paves the way for new clinical breakthroughs in treating degenerative diseases.
Researchers discovered newborn neurons and immature astroglia in patients with epilepsy, which could lead to new anti-seizure medications. The study suggests that targeting immature astroglia may be an effective approach to controlling seizures without aggressive brain surgery.
A clinical study from Lund University found that athletes with prolonged concussion symptoms have damaged nerves in the inner ear, particularly the vestibular nerve. This impairment leads to balance problems, dizziness, and difficulty focusing, affecting daily life.
Post-surgery patients exhibit moderate speech disorders affecting all language processing aspects, whereas post-stroke patients display specific phonological deficits. Understanding these differences is crucial for developing targeted therapies.
A new study by researchers at the University of Chicago Medicine has identified a set of sporadic genetic mutations that make it more likely a person will develop cavernous angiomas, which can lead to stroke and seizures. Understanding these underlying causes is key to identifying patients at risk and finding effective treatments.
When the eyes land on a face, certain cells in the amygdala react and trigger memory-making activity. Theta wave activity is also reset or restarted, preparing the hippocampus to receive new socially relevant information.