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University of Maryland leads multi-university research initiative to build smarter intelligence

A new research initiative aims to harness the potential of astrocytes, a type of brain cell often overlooked in AI development. By studying how astrocytes process information, researchers hope to create next-generation AI systems that learn faster and adapt more reliably.

Sophisticated neuroimaging reveals PTSD in WTC responders is linked to measurable physical changes in brain structure

A study among WTC responders with chronic PTSD found measurable physical changes in their brain structure, including cortical changes and imbalance of myelinated to unmyelinated neurons. These changes were most strongly associated with re-experiencing symptoms in individuals with PTSD.

SourceElsevier·JournalBiological Psychiatry Cognitive Neuroscience and Neuroimaging·TypeImaging analysis·DateDec 17, 2025

94% of the grey matter in the brains of mothers undergoes changes during pregnancy

A study analyzing the brains of women during pregnancy for the first time reveals that 94% of grey matter undergoes changes, particularly in social cognition regions. The research shows a reduction and partial recovery of brain volume, associated with steroid hormone fluctuations and maternal well-being.

SourceUniversitat Autonoma de Barcelona·JournalNature Communications·TypeObservational study·DateJan 17, 2025

Sex differences in brain structure present at birth

The study found that female infants had significantly more grey matter than male infants, while male infants had more white matter. These sex differences are average and do not imply better or worse brains, but rather reflect biological sex differences during prenatal brain development.

SourceUniversity of Cambridge·JournalBiology of Sex Differences·TypeData/statistical analysis·DateJan 7, 2025

New study finds neurobiological evidence of peripartum depression in women, distinguishing it from major depressive disorder

Researchers have identified structural grey matter differences in the brains of women with a history of peripartum depression compared to those without. The study found that hormone fluctuations during pregnancy and childbirth may be key to understanding this condition.

SourceElsevier·JournalBiological Psychiatry Cognitive Neuroscience and Neuroimaging·TypeImaging analysis·DateDec 5, 2024

Poor quality diet makes our brains sad

A study of 30 volunteers found that a poor diet can lead to changes in neurotransmitters and grey matter volume, commonly associated with depression and anxiety. Adhering to a Mediterranean-style diet was shown to prevent these changes.

SourceUniversity of Reading·JournalNutritional Neuroscience·TypeImaging analysis·DateJun 5, 2024

Physical fitness since childhood predicts cerebellar volume in adolescence

A recent study published in Scandinavian Journal of Medicine and Science in Sports found that physical fitness since childhood is associated with increased cerebellar grey matter volume in adolescents. Those with better neuromuscular fitness had larger Crus I grey matter volume, while those with cardiorespiratory fitness had smaller to...

SourceUniversity of Eastern Finland·JournalScandinavian Journal of Medicine and Science in Sports·DateNov 10, 2023

Exposure to plasticizers in pregnancy associated with smaller volumetric measures in the brain and lower IQ in children

Exposure to plasticizers during pregnancy has been linked to smaller total gray matter in the brains of children at age 10. Additionally, maternal exposure to certain phthalates is associated with lower child IQ at age 14. The relationship between exposure and lower IQ is partially influenced by total gray matter volumes.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalMolecular Psychiatry·TypeObservational study·DateSep 20, 2023

Cortical thinning is associated with altered neurotransmission in young adults with a history of heavy drinking since adolescence

Young adults with a history of heavy drinking since adolescence exhibit lower cortical gray matter thickness and altered neurotransmission, according to a recent study. Cortical thinning is associated with increased inhibitory neurotransmission, especially in the frontal and parietal lobes.

SourceUniversity of Eastern Finland·JournalAlcoholism Clinical and Experimental Research·DateJun 12, 2023

Fibromyalgia changes the brain

Researchers found changes in grey matter volume in pain-processing areas of the brain, with decreased volume in regions responsible for inhibiting pain. The study also revealed altered signal transmission in the thalamus and correlations between brain structure and perceptional characteristics.

SourceRuhr-University Bochum·JournalArthritis Research & Therapy·TypeObservational study·DateMay 26, 2023

How music can prevent cognitive decline

A study found that practicing music and active listening can alter cognitive decline in healthy seniors by promoting brain plasticity. The researchers discovered an increase in grey matter volume in four brain regions involved in high-level cognitive functioning.

SourceUniversité de Genève·JournalNeuroImage·TypeNews article·DateApr 17, 2023

Grey matter volume could inform treatment decisions for developing mental health disorders

A new study by researchers at the University of Birmingham has identified two distinct brain structure patterns associated with poor outcomes in patients with recent onset psychosis and depression. The study used MRI scans to analyze grey matter volume and found that lower volumes were linked to poorer outcomes, while higher volumes we...

SourceUniversity of Birmingham·JournalBiological Psychiatry·TypeExperimental study·DateApr 12, 2022

The relationship of education and income to brain and cognition varies across groups of people

A large study found that education and income have varying relationships with brain volume and cognitive scores across different populations. The associations were strongest in childhood development, suggesting socioeconomic status may not specifically protect the brain from aging effects.

Making the gray cells happy

Research using neutrons reveals a connection between lithium concentration and depression, with healthier individuals having more lithium in their gray matter. The findings suggest that lithium may play an important role in the body, with implications for therapy and understanding of physiological processes.

SourceTechnical University of Munich (TUM)·JournalScientific Reports·DateMay 21, 2021

Regular caffeine consumption affects brain structure

A study by researchers at the University of Basel found that regular caffeine intake can change the gray matter of the brain, but these effects are temporary. The study involved 20 healthy young individuals who were given caffeine or placebo tablets for two 10-day periods, with no sleep disruption observed.

SourceUniversity of Basel·JournalCerebral Cortex·DateFeb 15, 2021

How genetic variation gives rise to differences in mathematical ability

A study published in PLOS Biology found that genetic variants of the ROBO1 gene in young children are associated with grey matter volume in the right parietal cortex, predicting mathematical test scores. The research suggests that genetic variability may shape mathematical ability by influencing early brain development.

SourcePLOS·JournalPLOS Biology·DateOct 22, 2020

How does our brain fold? Study reveals new genetic insights

A new pre-clinical study identified genes linked with the development of brain folds in the grey matter of the brain. The research found differences in genetic expression and neuron shape during the folding process, which can lead to cognitive deficits and neurological conditions such as autism and schizophrenia.

SourceRMIT University·JournalCerebral Cortex·DateJul 1, 2020