Articles tagged with Thyroid Gland
The ESE and ESPE have launched a landmark Joint Clinical Practice Guidance to support structured and effective transition of young people with endocrine conditions. The Guidance provides practical, evidence-based recommendations to ensure continuity, safety and quality of care during this critical phase in a patient's life.
The European Society of Endocrinology is launching a new campaign to raise awareness about the importance of hormone health. The #BecauseHormonesMatter initiative aims to improve public understanding of hormones and promote practical steps for better hormone health, following the success of last year's campaign.
The European Society of Endocrinology has released the EndoCompass Research Roadmap, a major new initiative to align research efforts and improve funding strategies for hormone-related health challenges. The roadmap identifies specific research needs across eight endocrine specialties and five cross-cutting areas.
Research suggests that thyroid hormone treatment can improve gut health in individuals with hypothyroidism, particularly those with autoimmune thyroiditis. The study found a higher prevalence of SIBO in people with hypothyroidism compared to controls, which was mitigated by thyroid medication.
A study found that 10% of South Asian immigrants aged 45 and older in Canada had hypothyroidism. Higher dietary intake of fat, lower consumption of fruits and vegetables, and increasing age were associated with a higher risk of the condition. Early recognition and treatment are crucial to minimize preventable health impacts.
A new study at the University of Gothenburg found that a software robot can detect side effects faster than physicians during amiodarone treatment for cardiac arrhythmia. The robot also recommends appropriate intervals between lab tests, aligning with standard practices and reducing unnecessary testing.
A new study reveals that alpha male baboons' stress hormone levels are higher when they spend time monopolizing fertile females, not during aggression. This suggests that the demands of being a top-ranking male may be harmful to their health, leading to faster aging and shorter lives.
Dr. Seymour Reichlin's centennial celebration highlights his ongoing scientific impact, with recent collaborations yielding new insights into hormone therapies for cognitive enhancement and emotional homeostasis. His work has established neuroendocrinology as a distinct field, bridging neuroscience, endocrinology, and clinical medicine.
Four FAPESP-funded deep tech startups are looking to expand internationalization plans and enter new markets. The startups aim to establish strategic partnerships with universities, local companies, and research centers to validate their technologies and gain a better understanding of the challenges and specifics of the European market.
A recent study found that levothyroxine use is associated with greater loss of total body bone mass and density, even in participants with normal TSH levels. The research suggests that adults taking levothyroxine should discuss their treatment with their healthcare provider and regularly monitor their thyroid function tests.
Boston Medical Center and Boston University researchers have made a breakthrough in developing cell-based therapy for hypothyroidism. They derived transplantable thyroid follicular epithelial cells from human induced pluripotent stem cells, which can be transplanted into thyroid-deficient animal models.
Researchers have unveiled a complex interplay between liver X and thyroid hormone receptors that regulates critical brain functions and protects against neurodegeneration. LXRs play a crucial role in regulating thyroid hormone function in the brain, while both receptors are essential for normal brain development and maintenance.
A Carnegie Mellon-led team has secured a $42 million grant to develop implantable, cell-based bioelectronic devices for real-time therapy and disease monitoring in patients with thyroid disorders. The devices will offer adjustable, low-cost treatment and continuous biomarker measurement.
Researchers at Harvard Medical School discovered that thyroid hormone changes brain wiring to drive exploratory behavior, which is essential for survival during seasonal changes. The study found a link between thyroid hormone levels and metabolic rates, shedding light on the hormone's role in modulating behavior.
Scientists have developed a new compound, ZTA-261, which selectively binds to the thyroid hormone receptor beta (THRβ) to treat lipid disorders. Mice administered the drug showed decreased lipid levels in the liver and blood with fewer side effects compared to existing compounds.
A new study found that subclinical hypothyroidism before 21 weeks of pregnancy is associated with a more than quadrupled risk of overt hypothyroidism or thyroid replacement therapy within 5 years of delivery. Individuals with higher levels of antibodies against a thyroid enzyme were also at increased risk.
A new study found that pregnant women with lower socioeconomic status are exposed to higher levels of thyroid-disrupting chemicals, particularly polyaromatic hydrocarbons. This increased exposure has the potential to worsen health disparities among low-income populations.
A study found that patients with thyroid eye disease who received teprotumumab infusions maintained efficacy 51 weeks after treatment. Nearly two years later, 82% of patients did not require additional treatment for their condition.
A new compound found in fruit fly testes has the potential to control insect populations by suppressing their ability to reproduce. The enzyme, which is also present in other organisms, can lead to an overload of bromotyrosine that severely inhibits spermatogenesis.
A team of researchers from the University of Chicago has identified a genetic mutation in a non-coding region of DNA that alters thyroid hormone regulation, leading to a rare form of congenital thyroid abnormality. This discovery sheds light on a previously unexplained phenomenon and may lead to new treatments for individuals with this...
Researchers discovered that people with hypothyroidism are more likely to have a type D personality, which is characterized by pessimism and negative emotions. Those with both conditions experienced high levels of anxiety, depression, and dissatisfaction with treatment, highlighting the need for further research to improve outcomes.
A recent study published in Advanced Science has successfully regenerates thyroid glands in the spleen, restoring hormone levels and physiological homeostasis in mice with total thyroidectomy. The innovative approach leverages the spleen's unique properties to create a favorable environment for thyroid regeneration.
Researchers found that immunomodulatory drugs used to treat rheumatoid arthritis can reduce the risk of autoimmune thyroid diseases. Patients treated with these drugs had a 46% lower risk of developing an autoimmune thyroid disease compared to those without rheumatoid arthritis.
Researchers found that thyroid hormones of the mother during pregnancy affect the later activity of brown adipose tissue in offspring. High maternal thyroid hormone levels were associated with more active brown fat in offspring.
Researchers investigated the role of thyroid hormones in coordinating the metamorphosis of clownfish, discovering a strong interaction between metabolic processes and hormone regulation. Thyroid hormones play a critical role in timing the transformation and supporting energy demands during the journey.
Researchers found that radioactive iodine and thyroidectomy significantly increased survival rates for patients with hyperthyroidism. The treatments were associated with a decreased risk of death compared to antithyroid drugs, and had varying effects on weight gain.
The use of alternative thyroid hormone treatments is on the rise for hypothyroidism patients. A study found that desiccated thyroid extract (DTE) prescriptions have doubled over a decade, while T3 therapy has seen a significant increase in rural areas. Access to endocrine care may contribute to these disparities.
Researchers at UCLA Jonsson Comprehensive Cancer Center have found a potential therapeutic target, IL-21, to reduce endocrine autoimmune side effects from checkpoint immunotherapy. A specific group of immune cells play a central role in this autoimmune attack and blocking IL-21 prevents thyroid autoimmunity.
A diagnostic study involving 16 radiologists and 2,054 images suggests that optimized AI strategy reduces diagnostic time-based costs without sacrificing accuracy for senior radiologists. Traditional all-AI strategy may still be more beneficial for junior radiologists.
A recent study from Boston University School of Medicine found no significant differences in mortality among patients treated with propylthiouracil (PTU) or methimazole (MMI) for thyroid storm. The researchers compared the two drugs using a national database of hospitalization data and found no significant differences between the groups.
A Keck School of Medicine study found exposure to PFAS, known as 'forever chemicals,' disrupts key biological processes in children and young adults, increasing risk of diseases such as developmental disorders, cardiovascular disease, and cancer. The study highlights the importance of regulating PFAS as a class of chemicals.
A study found that competition preparation temporarily reduces resting energy expenditure in physique athletes, primarily due to reduced energy intake and lower levels of thyroid hormone T3. This reduction can complicate weight loss and make it difficult for athletes to compete.
A York University study found that higher fluoride levels in drinking water may increase the risk of hypothyroidism in pregnant women, associated with a 65% increased risk. The study also suggests a potential mechanism for lower IQs in boys born to mothers with higher fluoride exposure.
A retrospective study found associations between vitamin D levels and fine motor development delays, as well as thyroid hormones with cognitive development. Certain metals were also linked to language, cognitive, or motor skill development.
Researchers discovered that mild thyroid dysfunctions can lead to serious heart issues, with elevated free T4 levels increasing cardiovascular mortality. A systematic review of 32 studies found a direct correlation between FT4 concentrations and cardiac death, paving the way for personalized preventive care.
A deep learning algorithm trained on adult populations shows improved sensitivity for diagnosing thyroid nodules in children, with higher accuracy than traditional ACR TI-RADS. The study suggests the potential benefits of this new approach for evaluating thyroid nodules in younger patients.
A study published by the American Academy of Neurology found that older people with hypothyroidism may be at increased risk of developing dementia. Those taking thyroid hormone replacement medication had a three-fold higher risk. The association was strongest in people over 65 with hypothyroidism.
A new study by Vertice Pharma confirms that drinking coffee does not affect the absorption of a liquid formulation of levothyroxine. The research suggests that patients can take their medication with coffee without worrying about reduced absorption. This finding could lead to more flexibility in dosing and improved patient outcomes.
A new study presented at ENDO 2022 found that inactivated and mRNA COVID-19 vaccines do not cause significant fluctuations in thyroid function or increase the risk of emergency department visits among patients treated for hypothyroidism. The research suggests that these vaccines can be a safe option for this vulnerable population.
The Endocrine Society's ENDO 2022 news conferences will showcase the latest research on diabetes, obesity, thyroid health, and reproductive conditions. Key findings include the impact of chemicals in hair care products on breast cancer cells and the effects of childhood obesity on male infertility.
A study published in the Endocrine Society's Journal of Clinical Endocrinology and Metabolism found that undertreatment with thyroid hormone replacement can lead to longer hospital stays and higher readmission rates. Patients with high TSH levels before hospitalization had a 49% higher risk of 30-day readmission.
Intermittent fasting produces mild to moderate weight loss and improves cardiometabolic risk factors, comparable to traditional calorie-restricted diets. The review also dispels myths about intermittent fasting, including the misconception that it leads to weakness and decreased concentration.
Researchers discovered that toxic goiter causes shrinkage in central brain regions, such as the hippocampus and amygdala, which can lead to mental symptoms. The study provides key insights for patients with Graves' disease, a common form of hyperthyroidism.
Researchers at Children's Hospital of Philadelphia define a 3-tiered molecular classification system for pediatric differentiated thyroid cancer, where fusion oncogenes are associated with more invasive disease and lower remission rates. The study contrasts findings from adults, who have a two-tiered system based on BRAF mutations.
A study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that abnormal thyroid hormone levels during pregnancy may predict preschool boys' emotional and behavioral problems. Mothers with high thyroid hormone levels were more likely to have withdrawn, anxious, or depressed sons.
Researchers have developed a non-invasive method to diagnose thyroid cancer using photoacoustic and ultrasound image technology combined with artificial intelligence. The technique accurately classifies malignant nodules with high sensitivity and specificity, reducing unnecessary biopsies and medical costs.
Researchers used Mendelian randomization to analyze the genetic association between thyroid function and serum lipid profiles, finding a distinct causal relationship. The study highlights the importance of pituitary-thyroid-cardiac axis in diseases related to dyslipidemia.
A recent study by the University of the Basque Country found a direct relationship between exposure to fine particles and the level of thyroxine in newborns. The research analyzed data from the INMA project and revealed that exposure during early pregnancy has a significant impact on thyroid hormone balance.
The joint statement aims to address current controversies and evolving concepts in thyroid cancer care. Key findings include the use of molecular theranostics for refining management recommendations and indicators of response to RAI therapy. The statement was led by Seza Gulec, MD, and published in the peer-reviewed journal Thyroid.
Dr. Catherine F. Sinclair has been selected as the next Editor-in-Chief of VideoEndocrinology, a pioneering videojournal covering thyroid, parathyroid, and endocrine-related procedures. She brings extensive experience in surgical management of neck endocrine diseases and is an internationally recognized expert.
Dr. Anna M. Sawka, a renowned Clinician Scientist and Endocrinologist, has been appointed the next Editor-in-Chief of Thyroid, the Official Journal of the American Thyroid Association. She will lead the journal in advancing scientific publication in the field of Thyroidology.
The LUCA device, a low-cost near-infrared optical device combined with ultrasound, has shown potential in identifying benign or malignant thyroid nodules. Clinical tests demonstrated a 100% sensitivity and 77% specificity in classifying nodules as clear cases or those requiring further diagnosis.
Clownfish develop white stripes during metamorphosis, with varying rates of formation depending on the sea anemone host. Thyroid hormone influences white bar development, with higher concentrations leading to more bars and earlier development.
Researchers discovered that clownfish develop white stripes faster in giant carpet anemone hosts due to higher levels of thyroid hormones and increased duox gene activity. Thyroid hormone levels correlate with duox expression, leading to faster bar formation in giant carpet anemone clownfish.
A new study has found a link between early exposure to flame retardants and an increased risk of premature birth in pregnant women. Women with high levels of polybrominated diphenyl ethers (PBDEs) in their blood were more likely to deliver their babies early, with no such association seen for those with lower exposure levels.
Researchers investigating COVID-19's impact on the thyroid gland found atypical inflammation in 1/3 of patients after 3 months, raising concerns about potential long-term damage. The study aims to determine if this inflammation triggers permanent thyroid dysfunction.
Researchers found that combination therapy is equally effective to levothyroxine in treating hypothyroidism, with patients preferring DTE over other treatments. Desiccated thyroid extract (DTE) was shown to improve symptoms and lead to modest weight loss compared to levothyroxine.
A recent study found that nearly one-third of adults over 65 taking thyroid hormone also use medications known to interfere with thyroid function tests. The study highlights the complexity of managing thyroid hormone replacement in older adults, who often take multiple medications for other conditions.
Researchers have successfully generated lab-grown mini-thyroid organs from patients' own thyroid tissue, which can produce thyroid hormones. The study provides a potentially unlimited source of lab-grown thyroid tissue and may lead to new therapy options for hypothyroidism.
Thyroid hormone doesn't operate as a straight-on/off switch but rather shifts the balance between gene activity, revealing a more nuanced mechanism of action. This discovery has significant implications for understanding metabolic diseases and developing targeted therapies.