A new systematic review and meta-analysis published in The BMJ provides a comprehensive understanding of the adverse outcomes associated with gestational diabetes mellitus during pregnancy. The study found that women with gestational diabetes had increased odds of caesarean section, preterm delivery, and infant complications.
Researchers investigate how enzymes regulate metabolism, weight gain, and liver disease, revealing diet's significant role in obesity and altered lipid profiles. The study also shows that age affects metabolic processes, leading to weight gain, increased fat storage, and unhealthy liver changes.
A recent study found that only 3% of adults with a recording of overweight or obesity in England are referred to weight management programmes, indicating under-reporting in primary care. The programme's effectiveness varies across the country, and the lack of national registry makes it difficult to determine access for patients.
A UK study of over a million adults found that young adults (under 45) and women were more likely to gain weight and move up at least one BMI category during lockdown. The study suggests that this could lead to an increased risk of obesity-related health problems, including diabetes, heart disease, and cancer.
A UK study of over 400,000 adults with obesity found that losing weight reduces the risk of 13 obesity-related complications, with greater benefits for those with lower initial BMIs. Weight gain increases these risks, particularly in individuals with lower starting BMIs.
Researchers have developed a new implant that reduces ghrelin levels and body weight gain by half when exposed to laser light, offering a minimally invasive treatment option for obese patients. The implant uses a laser-activated dye to kill cells producing the 'hunger hormone'.
A large US survey found that adults gained weight during the COVID-19 pandemic due to changes in behavior such as increased snacking and alcohol intake. The analysis of more than 3.5 million adults also showed a 3% increase in obesity prevalence, with significant changes in exercise participation, sleep duration, and cigarette smoking.
SourceElsevier·JournalAmerican Journal of Preventive Medicine·TypeData/statistical analysis·DateApr 4, 2022
Researchers at the University of Bergen found that genes linked to extreme obesity, appetite, and energy consumption regulate child growth. The study, published in Nature Metabolism, provides insight into mechanisms controlling appetite and energy metabolism early in life, potentially leading to better treatment for obesity.
A new discovery could lead to modified thiazolidinediones with fewer side effects, benefiting more patients with diabetes. Activating only PPARγ2 eliminates the risk of weight gain while maintaining anti-diabetic effects.
A new randomized controlled trial found that making small changes to caloric intake and physical activity levels did not prevent long-term weight gain better than monitoring alone. Researchers observed reduced weight at 3, 6, 12, and 15 months but no significant difference by 24 months.
A rigorous randomized controlled trial found that adding a 300-calorie serving of French fries to one's diet daily for a month did not result in differential weight gain or biomarker changes compared to an isocaloric daily serving of almonds. The study measured body composition, blood sugar, and insulin levels, finding no clinically si...
A recent Mayo Clinic study found that community-based support can prevent and reverse weight gain, even during the COVID-19 pandemic. Participants who received peer-led intervention lost an average of 2% of their body weight while improving cardiovascular health measures.
A nationwide multi-cohort study found that male children who gained weight or grew faster in the first five years of life entered puberty at a younger age. Female children with faster weight gains during infancy and early childhood also started their periods earlier, suggesting sex-specific associations between early growth and puberta...
A new study reveals that middle-aged men perceive weight gain as an inevitable consequence of family and career commitments. The research found that these men experience low self-worth and despondency, despite awareness of health risks, due to a lack of education on nutrition and lifestyle factors.
A new study from the University of Texas at Austin found that rapid weight gain in pregnant women during the first and final months may lead to higher body mass index measurements, larger waist circumferences, and higher body fat percentages in their daughters by age 14. Researchers connected patterns of weight change in pregnancy to p...
Research finds that pregnant individuals living in walkable neighborhoods in NYC have lower odds of excessive gestational weight gain compared to those living elsewhere. High poverty rates in these areas are associated with increased risks of excessive GWG.
A new Penn State study found that Black youth with high BMIs reported fewer weight concerns when they had a strong sense of racial identity. Fathers also played a role in shaping their daughters' body image, particularly when involved in teaching about Black culture. The findings suggest that services promoting youth racial identity an...
Researchers found that giant pandas' gut microbiota shifts in season, helping them gain weight and store fat. The team used a fecal transplant experiment to show that the metabolic product of Clostridium butyricum can upregulate lipid synthesis and storage.
A recent study published in Scientific Reports found that chewing food thoroughly increases energy expenditure through diet-induced thermogenesis (DIT), which helps prevent obesity. The study involved participants who chewed liquid food for varying durations, revealing that prolonged chewing and tasting increased DIT, gas exchange, pro...
A large US-based study found that optimal gestational weight gain ranges associated with lower infant illness and death risks exist for different maternal weight categories. The study used birth data to identify these ranges and provide insights into the relationship between maternal weight gain and infant health outcomes.
A study by University of New South Wales has found that one in five future thyroid cancers in Australia is attributable to current levels of overweight and obesity. The prevalence of obesity has doubled in the last two decades, with 75% of Australian men and 60% of women being overweight or obese.
Researchers at the University of Pennsylvania found that mice with altered internal clocks gained more weight, had higher blood sugar, and fattier livers when fed high-fat and sugar diets. However, adjusting their environment to match their internal clock corrected these outcomes.
A recent study by the University of California - San Diego team discovered that glycogen regulates and promotes fat metabolism, helping to balance energy intake and expenditure. The research suggests modulating glycogen metabolism in fat cells could provide new approaches for weight loss and improved metabolic health.
About 42% of U.S. adults are considered clinically obese due to increased risk of health conditions such as diabetes and heart disease. New weight-loss drugs like Wegovy (semaglutide) show promise in safely aiding weight loss, but long-term side effects and sustainability remain concerns.
A team of researchers simulated the loss of physical activity during COVID19 lockdowns to study its effects on metabolism. They found that mice's energy sources shifted based on their diet composition after a sharp decline in exercise, leading to weight gain.
Researchers at the University of Virginia Health System have identified 14 genes that can cause and three that can prevent weight gain, offering a promising lead in developing new treatments for obesity. The findings were made using a worm model of obesity and automation to test hundreds of genes.
A new USC study found that artificial sweeteners like sucralose can trick the brain into feeling hungry, leading to increased calorie consumption. This study, one of the largest to-date on artificial sweeteners, suggests that females and people with obesity may be more sensitive to these sweeteners.
A University of Minnesota Medical School study found that nicotine withdrawal can lead to overeating high-calorie foods, possibly linked to the brain's opioid system. This connection may hinder smoking cessation and increase the risk of relapse, emphasizing the need for better understanding the factors driving cravings for unhealthy food.
A systematic review of 80 health industry studies found that pressuring children to eat negatively influences fussy eating, while a more relaxed parenting style and family meals reduce the likelihood. Researchers recommend positive parenting and involving kids in meal preparation to help them overcome picky eating habits.
A new study reveals that few recommendations exist for postpartum weight loss, with a focus on diet and exercise. Researchers emphasize the importance of supporting individuals with excessive weight gain or retention during pregnancy and the postpartum period to prevent obesity-related chronic diseases.
The energy balance model fails to explain the biological causes of weight gain, whereas the carbohydrate-insulin model identifies excessive consumption of rapidly digestible carbohydrates as a key contributor to obesity. This perspective argues for a shift in focus from calorie restriction to dietary pattern change.
Researchers found that young female black bears in Asheville, NC, weigh nearly twice as much as those in national forests and reproduce at a younger age, producing cubs by their second birthday. The study's findings raise questions about the diet and foraging activities of urban bears.
A new study found that young adults aged 18 to 24 are four times more likely to become overweight or develop obesity over the next 10 years than those aged 65 to 74. The study suggests that age is the most important sociodemographic factor for BMI change, and that targeted interventions for young adults may be necessary to prevent obes...
A Kaiser Permanente study of nearly 200,000 children found that those aged 5-11 gained more weight during the pandemic than teenagers. The result was a significant increase in overweight and obese children, highlighting the need for health-focused interventions to prevent long-term consequences.
Research at UTHealth School of Public Health in Houston found that infants born to obese mothers have a heightened risk of developing colorectal cancer later in life. The study also linked timing and magnitude of maternal weight gain during pregnancy, as well as birth weight, to increased risk of the disease.
A study by Kazan Federal University found that probiotics administered to antibiotic-treated mice improved behavior, reduced oxidative stress, and restored gut microbiota diversity. The researchers demonstrated a strong link between the gut microbiota and brain functioning, with potential therapeutic benefits for treating dysbiosis-rel...
A new study from the University of Georgia found that college students who were physically active before starting university remained so, while those with low motivation to exercise gained significant weight. The researchers recommend teaching children the importance of exercise and healthy eating habits.
Higher maternal weight during pregnancy may be associated with poorer offspring brain development into adolescence. The observational study found a positive correlation between maternal weight and brain development in offspring, suggesting potential long-term effects on cognitive function.
Research suggests that dieting is a consequence of an unhealthy food environment, rather than the cause of weight loss problems. Experts recommend refocusing concerns on changing the food environment to curb dieting and related issues.
A new study reveals that metabolism peaks in infancy, followed by a gradual decline until age 60, with the biggest slowdown after 90. The research suggests that tissue metabolism is changing over time, contradicting previous assumptions about lifestyle and body composition.
The Do IT Study assesses switching from INSTIs and TAF-containing regimens to doravirine-based treatments for weight gain reduction. The study aims to inform better strategies for managing ARV side effects in people living with HIV.
Researchers discovered that consuming concentrated chocolate in the morning can aid in burning fat and decreasing blood sugar levels. The study also found that eating chocolate at different times of day can influence hunger, appetite, microbiota composition, sleep, and metabolism.
Studies show that families report increased concerns about child weight gain during COVID-19, with snacking being a key contributor to nutrient-poor calories. Additionally, young people worldwide face barriers to healthy eating due to various factors.
A new study suggests that consuming high amounts of sugar from childhood can lead to significant weight gain, persistent hyperactivity, and learning impairments. Reducing sugar intake has been shown to prevent these issues, supporting World Health Organization recommendations.
The HealthyMoms app has been shown to improve a pregnant woman's diet and physical activity, leading to healthier weight gain. Women with overweight or obesity who used the app gained an average of 1.7 kg less weight than those in the control group.
The USPSTF recommends behavioral counseling interventions for promoting healthy weight gain and preventing excess gestational weight gain in pregnancy. Excess weight at the beginning of pregnancy is associated with adverse maternal and infant health outcomes, including cesarean delivery or preterm birth.
A recent study by the University of Washington found that living in a more densely populated neighborhood is associated with lower body weight and less obesity. However, proximity to fast-food restaurants or supermarkets did not have a significant impact on weight gain.
Researchers discovered that a gene called melanocortin 4 (Mc4r) plays a key role in weight gain associated with risperidone. A new drug approved for genetic obesity treatment, when combined with risperidone, prevents weight gain while maintaining therapeutic effect.
A study found that women who conceive within 12 months of bariatric surgery are at a higher risk of adverse outcomes in pregnancy, including lower gestational age and neonatal birth weights. Inadequate gestational weight gain was also linked to increased preterm births.
Research shows that physically active individuals who reach 100 PAI points per week have a lower risk of excessive weight gain. The study, which tracked over 85,000 healthy Norwegians for 20 years, found that maintaining at least 100 PAI points per week can help prevent unhealthy weight gain.
Researchers found that almonds contain approximately 20% unabsorbed calories after digestion, which can result in reduced energy absorption and potential weight loss. This finding could alleviate concerns about nuts contributing to weight gain, allowing for healthier snacking options.
A new study from the University of Bergen found that positive self-image and self-esteem protect against weight gain in adolescence. The study, which followed 1225 Norwegian adolescents over two years, revealed that body dissatisfaction and a desire to change one's body can impair self-rated health and self-esteem.
Research suggests that sleep disturbances during menopause may contribute to changes in the body that increase the risk of weight gain and related diseases. The study found that poor sleep reduced fat utilization, increasing the likelihood of fat storage and subsequent weight gain.
A large multicenter cohort study found that individuals switching to TAF therapy gained significantly more weight (1.7 kg) compared to those staying on TDF therapy (0.7 kg). The study also noted a negative development in lipid metabolism with an overall increase in blood lipid levels.
The study found that early PDA closure in extremely low birth weight infants with moderate to large PDA improved respiratory status, facilitated faster weaning off supplemental oxygen and ventilator support, and promoted normal weight gain. Delayed PDA closure and pulmonary hypertension were associated with worse respiratory outcomes.
Researchers found that actively preparing or watching others prepare food increases hunger and eating. Those who watched someone else prepare food or prepared their own nutritious food consumed more than those in the distraction group.
A recent study suggests that targeting a specific protein called eIF4E can reduce weight gain in mice fed a high-fat diet. The researchers found that these mice stored less fat and had improved liver health compared to their counterparts. Additionally, the modified mice showed enhanced lipid metabolism, allowing them to burn more fat.
Researchers investigate whether early prescription of metformin can prevent weight gain in children and teens diagnosed with bipolar disorder and schizophrenia. The study aims to identify patient subgroups who will benefit from early intervention, aiming to reduce the risk of type 2 diabetes and cardiovascular diseases.
Researchers at Johns Hopkins Medicine found that a majority of anorexia patients tolerated and met their weight gain goals on a rapid weight gain plan, with 70% reaching a healthy BMI. The study suggests that meal-based nutritional approaches can be well-tolerated and achieve weight restoration in a majority of patients.
A new drug, originally developed to treat bacterial infections, has shown the capacity to increase cell energy expenditure and reduce weight gain in mice fed a high-fat diet. The treatment works by reprogramming white adipose tissue cells to behave like brown adipose tissue, burning calories to generate heat.