Articles tagged with Cohort Studies
A cohort study reveals preterm individuals face increased mental health disorders and cardiometabolic issues compared to full-term peers. At age 35, these risks persist despite strong evidence linking preterm birth to long-term health consequences.
A retrospective cohort study found that COVID-19 booster vaccinations significantly protected against severe COVID-19, but uptake was low. Interventions are needed to increase COVID-19 vaccine uptake among high-risk populations with cancer.
A cohort study found that GLP-1RAs like semaglutide and tirzepatide lower risk of dementia, stroke, and all-cause mortality in adults with type 2 diabetes and obesity. The findings suggest potential neuroprotective benefits beyond glycemic control.
A longitudinal cohort study found that recreational cannabis legalization was associated with increased cannabis and electronic nicotine delivery systems use, but not a significant increase in cigarette use. The study suggests that commercialization policy should be closely monitored as retail cannabis expands.
Higher anticholinergic exposure accelerates decline in gait speed and grip strength in older adults, affecting healthy aging. The study suggests minimizing anticholinergic medications is crucial for maintaining physical function.
A newly developed microfluidic point-of-care device has been tested on a small cohort of patients, demonstrating strong correlation with laboratory measurements and high diagnostic performance. The device offers a promising alternative for bilirubin testing in resource-limited settings.
A community-based cohort study found that COVID-19 hospitalization was associated with accelerated declines in cognition among older adults, compared to those not infected. Avoiding severe SARS-CoV-2 infection may help preserve cognitive function in this population.
Access to buprenorphine and naltrexone for opioid use disorder is affected by race and ethnicity, as well as insurance type. Targeted interventions, including culturally tailored care and expanded access points, are needed to address disparities and reduce inequities contributing to the overdose crisis.
A study of 203 patients shows that electromagnetic navigation bronchoscopy (ENBDM) is a safer and faster alternative to CT-guided localization for preoperative treatment of multiple pulmonary nodules in the same lung. ENBDM achieved comparable accuracy with lower complication rates, making it an optimal strategy.
A cohort study suggests severe neonatal morbidity is a significant risk factor for childhood mortality, highlighting the importance of preventing and identifying early signs of severe conditions. Efforts to reduce mortality through infancy and late adolescence may benefit from targeted prevention strategies.
Researchers analyzed COVID-19 mortality among 5,813 patients in five Catalan hospitals. Patients without a ceiling of care had higher mortality during the first wave, but this decreased significantly over subsequent waves.
A cohort study reveals high support for care economy policies among all political affiliations, suggesting a policy window to address the needs of aging populations and those with disabilities. The results also highlight the importance of considering caregiving responsibilities when evaluating support for care economy policies.
The use of GLP-1 receptor agonists among diabetes patients is associated with a higher risk of developing incident neovascular age-related macular degeneration. Further research is needed to understand the underlying mechanisms and trade-offs between benefits and risks.
A cohort study of schools found that COVID-19-related decline in youth physical fitness persisted during the pandemic, but not associated with remote or hybrid environments. The reduction was observed in cardiorespiratory and musculoskeletal fitness healthy zone achievement.
A large cohort study found significant associations between incarceration and increased risk of death from overdoses, as well as a doubling of individual mortality risk at high county incarceration rates. The findings highlight the need for reforms in criminal justice and public health policies to address these risks.
A cohort study of 4 countries found that both maternal and paternal higher education levels were linked to reduced cognitive decline, with own education mediating these associations. The study highlights the long-term impact of parental education on offspring cognitive health across diverse cultural contexts.
A new GCAT study corrects selection biases in population-based cohorts, improving data reliability for public health research and precision medicine. The approach achieves a substantial reduction in bias, up to 70% in demographic variables and 26% in disease prevalence estimates.
A cohort study found that lower-than-recommended lead levels were associated with worse academic grades, suggesting the need to reconsider current blood lead reference values for further interventions. The findings support lowering these values to improve outcomes for children and adolescents.
Researchers identified unique symptom patterns and derived research indices for infants/toddlers and preschool-aged children, highlighting the need to characterize long COVID separately across age groups. The study provides new insights into the condition's progression in early childhood.
A cohort study found children on the path to obesity by age 3.5, highlighting modifiable risk factors that can be targeted in prevention programs. The Environmental influences on Child Health Outcomes (ECHO) cohort provided valuable insights into early-life factors and BMI trajectories.
A large-scale genetic study identified the FOXP4 gene as a significant factor in Long COVID, linked to lung health and immune response. The study found a strong relationship between severe COVID-19 cases and Long COVID, highlighting potential biological factors contributing to the condition.
A recent study published in PLOS ONE found that higher maternal selenium levels during pregnancy are associated with a lower risk of streptococcal infections in children. The research tracked over 74,000 mothers and their children to explore potential links between maternal metal exposure and infection risk.
A large cohort study found that early antibiotic treatment did not significantly improve outcomes for patients with nonsevere COVID-19. The results argue against routine antibiotic use in this population due to associated risks.
A cohort study found that high-quality carbohydrate intake and dietary fiber consumption were positively correlated with healthy outcomes in older adulthood. The study suggests that focusing on carbohydrate quality may be crucial for maintaining overall health as people age.
A cohort study found that long-term survival was similar among patients with low-risk early-stage cervical carcinoma who underwent simple, modified, or radical hysterectomy. These findings support the use of simple hysterectomy in select patients.
A study published in The Lancet Respiratory Medicine found that lung capacity develops in two phases: rapid growth during childhood and slower growth until peak lung function. Lung function starts to decline after the peak age, contrary to previous models. Persistent asthma and smoking affect lung function differently than thought.
A cohort study of US veterans found that depression is associated with a higher hazard of incident heart failure after controlling for demographic and cardiovascular risk factors. Depression remains consistent as a risk factor even in low-risk cohorts.
A study published in JAMA Neurology found no evidence supporting a diagnosis of the New Brunswick neurological syndrome of unknown cause, highlighting the need for independent clinical evaluations. The data revealed presence of several neurodegenerative and non-neurodegenerative conditions instead
A study of three national cohorts reveals increased abortion use among LGBTQ+ individuals, highlighting the need for tailored support. The findings suggest that these groups are disproportionately impacted by narrowing abortion access in the US after the Dobbs decision.
A recent study has found that increasing physical activity between the ages of 45 and 65 can help reduce the accumulation of beta-amyloid, a protein linked to Alzheimer's disease. The research, led by ISGlobal, suggests that even minimal amounts of exercise have health benefits for brain health.
Exposure to high levels of smoke pollution increases hospitalizations for respiratory diseases in older adults. The study highlights the need for interventions to mitigate the health impacts of wildfire smoke exposure.
A cohort study found that vaccination against influenza alone or with COVID-19 was associated with a small but temporary change in menstrual cycle length. This finding may help clinicians confirm the utility of vaccination for patients concerned about menstrual side effects.
A cohort study found associations between pre-pregnancy overweight, smoking during pregnancy, and formula-feeding with adverse cardiovascular health trajectories in early childhood. The study suggests that addressing these factors through interventions may optimize cardiovascular health in children.
A cohort study found maternal hypertension and preeclampsia independently associated with cognitive and language development delays in preterm infants. Recognizing hypertensive disorders of pregnancy is crucial for targeted risk management strategies.
A study found that genetic predisposition to higher muscle strength is associated with lower all-cause and cardiovascular mortality in aging men. The association remained significant even after adjusting for lifestyle factors such as smoking and body mass index.
Researchers found that pooling data across studies can accurately identify dose-response relationships, particularly for chemicals with low-dose effects. The study suggests that combining individual study data can strengthen conclusions in environmental health research.
The study reveals wide disparities in mortality across US states, with some experiencing no improvements in life expectancy from 1900 to 2000 birth cohorts. This disparity can inform decision-making around resource allocation and public health interventions.
A cohort study of pregnant individuals with opioid use disorder found that buprenorphine treatment was associated with improved maternal and infant outcomes. The study highlights the need to improve access to treatment nationwide for these patients.
A study found that exposure to traffic-related air pollution in childhood is associated with increased body mass index (BMI) and insulin resistance later in life. Higher BMI growth from early adolescence into young adulthood may partially explain this link.
A study of nearly 11,000 individuals found that men with panic disorder are more vulnerable to developing problematic drinking behaviors than women, potentially due to self-medication. The research highlights the need for sex-specific assessment and intervention strategies in treating comorbid conditions
A study found that hazardous drinking and daily alcohol consumption were associated with increased odds of abusive and neglectful behaviors among family caregivers of patients with dementia. The findings suggest the importance of addressing caregiving complexities and alcohol use patterns through personalized interventions.
A research team of over 60,000 OB-GYNs in the US found that doctors are not systematically leaving states where abortions are banned or threatened. The study suggests that concerns about reproductive health care may be offset by ties to patients and local communities, as well as significant relocation efforts.
A cohort study found that hearing loss is associated with an increased risk of incident dementia in older adults. Treating hearing loss may help delay dementia onset for a large number of people, suggesting potential benefits for dementia prevention.
A noise-adapted AI model using lead I ECGs estimated heart failure risk with high accuracy, suggesting a potential strategy for early detection. The study's results highlight the promise of wearable and portable ECG devices in identifying at-risk patients.
A cohort study found that women with screen-detected estrogen receptor–positive or human epidermal growth factor receptor 2–negative breast cancer who underwent prior screening had an earlier stage of diagnosis and lower breast cancer mortality compared to those who did not undergo prior screening.
The study found an increase in pancreatic adenocarcinoma among all age groups, while a notable rise was observed in colorectal adenocarcinoma among younger patients. This trend highlights the importance of early detection and evaluation for clinicians when evaluating patients with relevant symptoms.
A large US cohort study found SARS-CoV-2 infection associated with adverse postacute kidney outcomes in children and adolescents, especially those with chronic or acute kidney disease. Long-term monitoring is recommended for these patients.
Severe RSV disease among children is more likely those aged 2 or older with pulmonary or neurologic conditions. Younger children under 6 months and prematurity are high-risk factors for severe RSV in younger kids.
A new NIH study found that children born in lower-opportunity neighborhoods are more likely to experience repeated asthma flares requiring emergency care. Non-Hispanic Black children have the highest incidence rates of severe childhood asthma, also known as asthma with recurrent exacerbations (ARE).
A USF-led study found that when some members in a cohort engage in job-seeking behaviors, newcomers are more likely to do the same and ultimately leave the organization. The effect is mitigated if the newcomer has a strong preference for the organization's geographic location.
A French cohort study of over 100,000 adults found that mixtures of common food additives, including aspartame and carrageenan, were associated with a slightly increased risk of type II diabetes. The study suggests that these additives may have adverse effects on glucose metabolism.
A new study analyzed health data of over 100,000 adults and found that two food additive mixtures were associated with a higher incidence of type 2 diabetes. The mixtures contained emulsifiers, sweeteners, and colourings commonly found in ultra-processed foods.
A cohort study found early-life ozone exposure was associated with increased asthma and wheeze outcomes at ages 4-6, but not at age 8-9. Regulating ozone exposure may help mitigate the significant public health burden of asthma among US children.
A new study found that children exposed to higher levels of air pollution have weaker connections between key brain regions, potentially disrupting normal brain network development. The associations persist throughout adolescence, suggesting persistent disruptions in brain function.
Hormonal contraceptives initiated immediately after childbirth may increase the risk of developing depression in new mothers. Researchers found that combined oral contraceptives were associated with a higher risk of depression when started earlier postpartum.
Ferric carboxymaltose did not significantly reduce time to first heart failure hospitalization or cardiovascular death in patients with heart failure and iron deficiency. The treatment also did not reduce total number of heart failure hospitalizations compared to placebo.
A cohort study found semaglutide use is associated with a higher risk of nonarteritic anterior ischemic optic neuropathy in people with diabetes. However, the retrospective design limits the study's ability to establish causality, necessitating further research.
Research presented at #AGS25 sheds light on the impact of aging on physical resilience, with declines linked to mitochondrial function. Family caregiver distress also shows a significant association with care outcomes, including nursing home placement and psychotropic medication prescribing.
A large cohort study found living alone to be a critical factor in suicide risk assessments for individuals with depression and anxiety. The study of 3.7 million individuals highlighted the importance of preventing mental illness while addressing living arrangements.
A cohort study suggests that many comatose patients who died after withdrawing life-sustaining therapy had recovery potential. Experts emphasize the need for novel solutions to avoid deaths based on biased prognostication or incomplete information.