Articles tagged with Cohort Studies
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A noise-adapted AI model using lead I ECGs estimated heart failure risk with high accuracy, suggesting a potential strategy for early detection. The study's results highlight the promise of wearable and portable ECG devices in identifying at-risk patients.
A cohort study found that women with screen-detected estrogen receptor–positive or human epidermal growth factor receptor 2–negative breast cancer who underwent prior screening had an earlier stage of diagnosis and lower breast cancer mortality compared to those who did not undergo prior screening.
The study found an increase in pancreatic adenocarcinoma among all age groups, while a notable rise was observed in colorectal adenocarcinoma among younger patients. This trend highlights the importance of early detection and evaluation for clinicians when evaluating patients with relevant symptoms.
Severe RSV disease among children is more likely those aged 2 or older with pulmonary or neurologic conditions. Younger children under 6 months and prematurity are high-risk factors for severe RSV in younger kids.
A large US cohort study found SARS-CoV-2 infection associated with adverse postacute kidney outcomes in children and adolescents, especially those with chronic or acute kidney disease. Long-term monitoring is recommended for these patients.
A USF-led study found that when some members in a cohort engage in job-seeking behaviors, newcomers are more likely to do the same and ultimately leave the organization. The effect is mitigated if the newcomer has a strong preference for the organization's geographic location.
A new NIH study found that children born in lower-opportunity neighborhoods are more likely to experience repeated asthma flares requiring emergency care. Non-Hispanic Black children have the highest incidence rates of severe childhood asthma, also known as asthma with recurrent exacerbations (ARE).
A new study analyzed health data of over 100,000 adults and found that two food additive mixtures were associated with a higher incidence of type 2 diabetes. The mixtures contained emulsifiers, sweeteners, and colourings commonly found in ultra-processed foods.
A French cohort study of over 100,000 adults found that mixtures of common food additives, including aspartame and carrageenan, were associated with a slightly increased risk of type II diabetes. The study suggests that these additives may have adverse effects on glucose metabolism.
A cohort study found early-life ozone exposure was associated with increased asthma and wheeze outcomes at ages 4-6, but not at age 8-9. Regulating ozone exposure may help mitigate the significant public health burden of asthma among US children.
A new study found that children exposed to higher levels of air pollution have weaker connections between key brain regions, potentially disrupting normal brain network development. The associations persist throughout adolescence, suggesting persistent disruptions in brain function.
Hormonal contraceptives initiated immediately after childbirth may increase the risk of developing depression in new mothers. Researchers found that combined oral contraceptives were associated with a higher risk of depression when started earlier postpartum.
Ferric carboxymaltose did not significantly reduce time to first heart failure hospitalization or cardiovascular death in patients with heart failure and iron deficiency. The treatment also did not reduce total number of heart failure hospitalizations compared to placebo.
A cohort study found semaglutide use is associated with a higher risk of nonarteritic anterior ischemic optic neuropathy in people with diabetes. However, the retrospective design limits the study's ability to establish causality, necessitating further research.
A large cohort study found living alone to be a critical factor in suicide risk assessments for individuals with depression and anxiety. The study of 3.7 million individuals highlighted the importance of preventing mental illness while addressing living arrangements.
Research presented at #AGS25 sheds light on the impact of aging on physical resilience, with declines linked to mitochondrial function. Family caregiver distress also shows a significant association with care outcomes, including nursing home placement and psychotropic medication prescribing.
A growing body of evidence suggests a significant link between human papillomavirus (HPV) and heart disease. Researchers pooled data from nearly 250,000 patients in seven studies, finding HPV-positive individuals had a 40% higher likelihood of developing cardiovascular disease.
A cohort study suggests that many comatose patients who died after withdrawing life-sustaining therapy had recovery potential. Experts emphasize the need for novel solutions to avoid deaths based on biased prognostication or incomplete information.
The POSTECH research team developed a smartphone-type OLED panel that can transform its shape while functioning as a speaker, maintaining ultra-thin flexibility. The panel uses electrically driven piezoelectric polymer actuators to achieve complex forms without mechanical hinges or motors.
A cohort study reveals lower-quality hospitals for Black and American Indian birthing individuals compared to their white counterparts. Delivering at nearest hospitals would have reduced the disparity if available.
Researchers found a significant association between state earned income tax credits and lower firearm suicide rates. The study suggests that targeted antipoverty policies can help mitigate the link between economic hardship and gun violence.
Patients from American Indian and Black communities are less likely to have elevated CA-125 levels at diagnosis, suggesting current thresholds may miss diverse patients. Inclusive diagnostic guidelines are needed to address disparities in ovarian cancer diagnosis and treatment.
This cohort study found that geographic access to cancer care is associated with guideline-recommended treatment for early-stage non–small cell lung cancer. Socially marginalized patients benefited from improved treatment outcomes and prognosis when accessing care in their local area.
A multicenter cohort study found that higher adherence to annual lung cancer screening was associated with increased overall and early-stage lung cancer detection rates. However, adherence decreased over time, suggesting it is a critical quality metric for lung cancer screening.
A longitudinal observational cohort study found that gender-affirming hormone therapy was associated with lower rates of moderate-to-severe depressive symptoms. The study highlights the importance of gender-affirming primary care models for transgender, nonbinary, and gender diverse patients.
A recent cohort study published in JAMA Internal Medicine found that statin use was associated with a reduced risk of hepatocellular carcinoma and hepatic decompensation in patients with chronic liver disease. This suggests that statins may play a role in preventing the progression of liver disease and reducing the risk of liver cancer.
Research proposes a new methodology for dynamically optimizing solar panel positioning based on the light needs of crops. Advanced ray tracing techniques are used to evaluate the distribution of solar radiation, enabling the automation of design optimization of agrivoltaic systems.
A study found that RSV hospitalization rates increase progressively with age among older adults in Spain, with those over 85 years old facing the highest risk. Certain chronic conditions, such as blood cancer, COPD, and cardiovascular disease, also significantly increase the risk of hospitalization.
A study from the University of Gothenburg found that young teenagers in Sweden reported higher depressive symptoms over two decades, with a greater proportion of adolescents feeling extremely well. Those who are struggling report feeling significantly worse, with increased self-deprecation among young women.
A prospective cohort study found a significant association between food insecurity and incident cardiovascular disease in both Black and White US individuals. Food insecurity was also shown to be an important social deprivation measure for assessing CVD risk, highlighting its potential as a key factor in clinical assessment.
A cohort study found that healthier diets and lower waist-to-hip ratios were associated with improved brain connectivity and memory in older adults. The study suggests that interventions targeting diet and central obesity may be most effective between ages 48 and 70 to promote better cognitive health.
A new Northwestern Medicine study reveals that young adults experiencing food insecurity have a 41% greater risk of developing heart disease in midlife. Food insecurity affects one in eight households in the US, and addressing it early may help reduce the burden of heart disease later.
A new study led by researchers at UCL has found that online brain speed tests can provide valuable insights into cognitive function and potentially shed light on dementia development. The tests, which measure reaction times, were designed to be easy and convenient for women in their 40s and older to participate from home.
A cohort study found that consuming more butter was associated with higher mortality rates, whereas increasing consumption of plant-based oils was linked to lower mortality. Substituting butter with plant-based oils may provide substantial benefits in preventing premature deaths.
This cohort study found persistent inadequate sleep duration and late sleep onset linked to increased glycemic variability in adults. The study emphasizes the importance of considering both sleep duration and timing for optimizing glycemic control.
The European Genome-phenome Archive has released the largest ever DNA sequencing dataset on UK child development studies, containing high-resolution data from over 37,000 children and parents. This comprehensive resource can be used to investigate genetic variation's impact on neurodevelopmental conditions and childhood obesity.
A cohort study found no significant association between preoperative GLP-1 RA use and short-term postoperative aspiration pneumonia. The study suggests reassessing preoperative withholding guidelines for GLP-1 RAs. Researchers hope this finding can help alleviate growing concerns about adverse effects of these medications after surgery.
Researchers from the University of Southern Denmark found that tattooed individuals are more frequently diagnosed with skin and lymphoma cancers compared to those without tattoos. The study suggests that chronic inflammation in the lymph nodes triggered by tattoo ink may lead to abnormal cell growth and an increased risk of cancer.
A cohort study of 46,000 US residents found nearly two-thirds had suboptimal 5-year sleep duration trajectories, associated with increased risk of mortality. Maintaining healthy sleep duration is crucial for reducing mortality risk in this population.
A new study of 2,900 patients with lupus pericarditis found that using corticosteroids increases the risk of recurring pericarditis. The study suggests minimizing corticosteroid use and exploring alternative treatments to reduce recurrence rates.
Research on treating moderate aortic valve dysfunction during rheumatic mitral valve surgery shows concomitant aortic valve surgery may improve echocardiographic outcomes. The study suggests delaying aortic valve surgery may be a viable option for patients with moderate predominant aortic regurgitation.
A cohort study found that telemedicine adoption was associated with modestly lower use of 7 out of 20 examined low-value tests, while having no effect on other tests. The results suggest potential benefits of telemedicine and mitigate concerns about increased spending.
A cohort study found no increase in sudden cardiac arrest/sudden cardiac death among young competitive athletes in the US, contradicting reports that linked COVID-19 infection and vaccination to the risk. The study suggests that many athlete cases shown in social media videos occurred before the pandemic, not due to COVID-19.
A retrospective cohort study from the University of Ottawa and Manitoba found Canadians with hypertension whose preferred language was spoken by their doctor were 36% less likely to have a major adverse cardiovascular event. Patients with language-accessible care had a 28% lower risk of death compared to those without such access.
A cohort study found that patients with obesity undergoing joint replacement who experienced significant weight loss after initiating anti-obesity medications had a lower risk of 5-year and 10-year revision. This suggests that safe and sustainable weight loss may improve implant survivorship in obese patients.
A recent study has identified that the neuronal subtype responds best to immunotherapy, while other subtypes exhibit lower response rates. The researchers developed a machine-learning algorithm using large public data sets to predict treatment response based on tumor mutational burden and immune cell infiltration.
Researchers found significant disparities in behavioral flag incidence among racially and socioeconomically marginalized pediatric patients. Black or African American patients younger than 8 years were disproportionately affected.
A new study from the University of Texas at Arlington found that Americans aged 65 and older who experienced parental divorce as children were more likely to suffer a stroke compared to their peers. The study analyzed data from over 13,000 older Americans and found that about 14% had experienced parental divorce during childhood.
A Finnish cohort study found that higher physical activity and lower screen time in childhood are associated with reduced perceived stress and depressive symptoms in adolescence. The findings emphasize the importance of promoting physical activity and reducing screen time to support mental health in youth.
Researchers identified two new patterns in childhood BMI development, differing from the traditional 'Type 1' trajectory. Type 2 and Type 3 trajectories have distinct profiles, with Type 2 showing a steeper rise and fall before and after infancy peak, while Type 3 has more irregular peaks and troughs.
A cohort study found ADHD symptoms among US youths increased risk of nicotine and tobacco use. Early ADHD diagnosis and effective treatment may help alleviate symptoms and reduce the risk of nicotine and tobacco use.
During the COVID-19 pandemic, primary care practices in the US experienced declining access to care, while average practice capabilities improved. Integrated practice ownership and accountable care organization participation were associated with better access and capability scores.
Residents of Ontario with cannabis use disorder had a significantly higher risk of death compared to the general population. The findings highlight the importance of addressing cannabis use disorders, especially as global trends toward cannabis legalization continue.
Researchers identified inequities related to race and rurality in healthcare-associated infections (HAIs) and adverse outcomes. Structural racism and disinvestment in rural communities may be linked to individual HAI risk and post-HAI outcomes.
Research found that long-term exposure to air pollutants like PM2.5, NO2, and ozone increases hospital admissions for lower respiratory tract infections in adults, particularly among men and people over 65. The study used a large cohort of adults from Catalonia and found stronger associations in these vulnerable groups.
A global study published in JACC found that secondary prevention medications for cardiovascular diseases are underused worldwide, with little improvement over time. Medication use varied by country income level, with lower rates in low-income countries.
A cohort study reveals a robust association between headache diagnoses and suicidal behavior, highlighting the importance of behavioral health evaluation and treatment for these patients. The findings suggest that patients with headache diagnoses should be screened for suicidal ideation and provided with appropriate support.
A cohort study found that patients without type 2 diabetes had higher discontinuation rates and lower reinitiation rates of GLP-1 receptor agonist therapy. Inequities in access and adherence to effective treatments exacerbate disparities in obesity.
A cohort study of Canadian children found that high ultraprocessed food consumption during early childhood is associated with obesity development, particularly in males. The study suggests that targeted public health initiatives can help reduce ultraprocessed food intake and prevent obesity.
The study found a significant decrease in antidepressant use during pregnancy without an accompanying increase in psychotherapy. This suggests that pregnant women with depression or anxiety may be able to effectively manage their symptoms with medication alone.