Articles tagged with Cohort Studies
A cohort study found that night light exposure was a significant risk factor for developing cardiovascular diseases among adults over 40. Avoiding light at night may be a useful strategy for reducing the risks of cardiovascular diseases.
A large cohort study found associations between prenatal fine particulate matter components and postnatal ozone exposure with increased risk of autism spectrum disorder. These findings suggest that air pollution may play a role in the etiology of autism, warranting further research.
A German study using a digital cohort dataset found that twenty percent of participants had unreported polio vaccinations, while forty percent of documented doses were unidentified. The study emphasizes the need for improved vaccine tracking and booster vaccination strategies to ensure effective population protection.
A large national cohort study found associations between adverse pregnancy outcomes and increased risk of atrial fibrillation up to 46 years later. Women with these outcomes require early preventive actions and long-term clinical follow-up.
Black and Asian patients were underrepresented in clinical trials, leading to worse survival outcomes compared to white counterparts, despite similar progression-free survival rates. Equitable enrollment is crucial for access to cutting-edge treatments and long-term equity in cancer care.
A cohort study of mRNA COVID-19 vaccine exposure in the first trimester found no association with major congenital malformations. The study supports the safety of mRNA COVID-19 vaccines during early pregnancy.
A cohort study reveals a significant association between social adversity and increased incidence of triple-negative breast cancer in Black women. The findings suggest potential social genomic and gene-environment interactions that contribute to disparities in breast cancer survival.
A study published in BMC Medicine reveals that vascular dysfunction is a key mechanism in long COVID, especially in postmenopausal women. The researchers identified the VEGFA protein as a central element in this process, highlighting its role in blood vessel formation and vascular function.
Full-term children exposed to antenatal corticosteroids are at higher risk of infections until age 21, a new study finds. Preterm children, however, show no association between ACS and infections.
A cohort study found that early extracranial surgery was associated with adverse outcomes in function, cognition, and disability after moderate-severe traumatic brain injury. The study suggests that further research is needed to determine if surgical timing or other interventions can improve long-term deficits.
A cohort study found that 40% of GLP-1RA orders were not filled, with lower rates among Non-Hispanic Black and Hispanic patients. These disparities may be attributed to differences in insurance coverage, GLP-1RA use, or cost thresholds.
The implementation of a surgical handover system prioritizing sickest patients first improved handover quality, patient physiology, and staff perceptions of safety. The study found no increase in meeting duration.
An AI model successfully automates lymph node segmentation and extranodal extension classification from pretreatment CT scans in HPV-associated oropharyngeal carcinoma. Predicted extranodal extension is independently associated with worse oncologic outcomes, highlighting the potential for improved treatment planning.
A cohort study investigated olfactory dysfunction in US adults with and without prior SARS-CoV-2 infection. The study found a significant association between prior infection and persistent olfactory dysfunction. High variability was observed among individuals, highlighting the need for individualized assessment and treatment strategies.
School participation in universal free meals was associated with a net reduction in blood pressure outcomes among youths, according to a cohort study. The findings contribute to growing evidence that such programs may improve child health.
A cohort study reveals oral bacteria and fungi as significant risk factors for pancreatic cancer development. The findings suggest that oral microbiota may serve as biomarkers to identify individuals at high risk of pancreatic cancer, potentially contributing to personalized prevention strategies.
A cohort study suggests nicotinamide reduces skin cancer risk, with greatest effect seen after initial skin cancer diagnosis, indicating potential chemopreventive properties of the vitamin B3 derivative
This cohort study found that receiving encounters with behavioral health clinicians and psychotropic prescriptions was associated with reduced psychosocial symptoms. The results suggest that expanding integrated pediatric behavioral health care could improve outcomes among vulnerable child populations.
A cohort study found an association between parental diseases of despair and youth suicidal events, suggesting a potential underlying factor in the increase in adolescent suicidal behavior. Improved access to care for parents with these conditions may help reduce the adolescent suicide rate.
A cohort study found that childhood loneliness was associated with cognitive decline and increased dementia risk in later life. Early interventions may help promote lifelong cognitive health and reduce dementia risk.
A retrospective cohort study found that children of racial and ethnic minority groups receiving CPR had higher odds of in-hospital mortality. Additionally, the odds of in-hospital mortality among children receiving CPR were higher at hospitals with the highest proportion of Black patients.
A cohort study shows bariatric surgery significantly lowers major metabolic comorbidity risk compared to medical weight management. The procedure is deemed a durable approach for obesity-related risk mitigation.
A cohort study found GLP-1 RAs offer body mass index-dependent cardiovascular benefits and consistent kidney protection for type 2 diabetes patients. The study suggests BMI stratification is crucial for guiding treatment decisions.
A retrospective cohort study found that GLP-1 receptor agonists may reduce overall cancer risk, including lower risks of endometrial and ovarian cancers, among patients with obesity or overweight. However, these medications may also increase the risk of kidney cancer, highlighting the need for longer-term follow-up.
A cohort study found a higher prevalence of eating disorders among adolescents from lower socioeconomic backgrounds. The study suggests that reducing population-level socioeconomic inequalities may aid in preventing eating disorders.
A study of over 10,000 teenagers found that sleep problems at age 14 were directly associated with self-harm behaviour at both ages, highlighting the importance of prioritizing sleep health in adolescents. The research also suggests that poor sleep can have long-lasting impacts on mental health.
A new article by Dr. Leonard Berry of Texas A&M University argues that values-driven listening can improve care and heal the healthcare system. The authors identify six types of listening, including proximate, curious, earning trust, aided by design, empowering, and fostering resilience, which contribute to better care.
A cohort study found that hospitals with poor financial health were less likely to provide essential perinatal services. This disparity was more pronounced in Southern and rural regions.
Adults with long COVID experience worse work impairment, missed work, and financial distress compared to those without long COVID. Vaccination is associated with improved work outcomes and reduced financial distress among individuals with long COVID.
Initiation of semaglutide in adults leads to reductions in weight and cardiovascular risk factors, while increasing health care expenditures. These findings suggest potential clinical benefits, highlighting the need for long-term evaluation of semaglutide's economic impact.
Research shows that the 2025 Los Angeles wildfires resulted in an estimated 440 excess deaths, while the 2023 Maui wildfires led to immediate increases in suicide and overdose deaths. Higher social support was linked to improved mental health outcomes but did not buffer physiological effects.
A study of over 452,000 adults found that metformin users had significantly lower risks of dementia and all-cause death compared to non-users. The benefits were seen across all categories of overweight and obesity, with reduced risks of up to 26% for death.
A multicenter study found that preoperative Mini-Cog scores can predict postoperative delirium risk in elderly patients. The study used a mendelian randomization analysis to identify genetic variants associated with cognitive performance, suggesting that preoperative screening may help identify high-risk patients.
A pilot cohort study assesses the efficacy of a microfluidic-based point-of-care bilirubin measurement system in detecting bilirubin levels with high accuracy, comparable to standard clinical laboratory methods. The device's miniaturized optical sensing module and microfluidic test cartridge enable scalable adoption and portability.
A cohort study found that stroke center certification decreases racial disparities in treatment for white patients within the same hospital, but such disparities remain for Black patients. This suggests continued systemic inequalities in stroke care settings.
A case series of children with influenza-associated acute necrotizing encephalopathy highlights the condition's severe impact on young, previously healthy children. The study emphasizes the need for prevention, early recognition, intensive treatment, and standardized management protocols to address this critical public health concern.
A nationwide cohort study of 1 million adults found no increased risk of 29 adverse events after vaccination with the updated COVID-19 mRNA vaccine containing the SARS-CoV-2 Omicron JN.1 lineage. The study provides reassuring safety data on the new vaccine, which has been widely adopted in response to the Omicron variant
This study found that moderate to vigorous-intensity physical activity declined from early adulthood to midlife, with notable demographic differences. Black women experienced the lowest physical activity across adulthood and highest risk of low physical activity post-CVD.
A cohort study reveals preterm individuals face increased mental health disorders and cardiometabolic issues compared to full-term peers. At age 35, these risks persist despite strong evidence linking preterm birth to long-term health consequences.
A retrospective cohort study found that COVID-19 booster vaccinations significantly protected against severe COVID-19, but uptake was low. Interventions are needed to increase COVID-19 vaccine uptake among high-risk populations with cancer.
A cohort study found that GLP-1RAs like semaglutide and tirzepatide lower risk of dementia, stroke, and all-cause mortality in adults with type 2 diabetes and obesity. The findings suggest potential neuroprotective benefits beyond glycemic control.
A longitudinal cohort study found that recreational cannabis legalization was associated with increased cannabis and electronic nicotine delivery systems use, but not a significant increase in cigarette use. The study suggests that commercialization policy should be closely monitored as retail cannabis expands.
Higher anticholinergic exposure accelerates decline in gait speed and grip strength in older adults, affecting healthy aging. The study suggests minimizing anticholinergic medications is crucial for maintaining physical function.
A newly developed microfluidic point-of-care device has been tested on a small cohort of patients, demonstrating strong correlation with laboratory measurements and high diagnostic performance. The device offers a promising alternative for bilirubin testing in resource-limited settings.
A community-based cohort study found that COVID-19 hospitalization was associated with accelerated declines in cognition among older adults, compared to those not infected. Avoiding severe SARS-CoV-2 infection may help preserve cognitive function in this population.
Access to buprenorphine and naltrexone for opioid use disorder is affected by race and ethnicity, as well as insurance type. Targeted interventions, including culturally tailored care and expanded access points, are needed to address disparities and reduce inequities contributing to the overdose crisis.
A study of 203 patients shows that electromagnetic navigation bronchoscopy (ENBDM) is a safer and faster alternative to CT-guided localization for preoperative treatment of multiple pulmonary nodules in the same lung. ENBDM achieved comparable accuracy with lower complication rates, making it an optimal strategy.
A cohort study suggests severe neonatal morbidity is a significant risk factor for childhood mortality, highlighting the importance of preventing and identifying early signs of severe conditions. Efforts to reduce mortality through infancy and late adolescence may benefit from targeted prevention strategies.
Researchers analyzed COVID-19 mortality among 5,813 patients in five Catalan hospitals. Patients without a ceiling of care had higher mortality during the first wave, but this decreased significantly over subsequent waves.
A cohort study reveals high support for care economy policies among all political affiliations, suggesting a policy window to address the needs of aging populations and those with disabilities. The results also highlight the importance of considering caregiving responsibilities when evaluating support for care economy policies.
The use of GLP-1 receptor agonists among diabetes patients is associated with a higher risk of developing incident neovascular age-related macular degeneration. Further research is needed to understand the underlying mechanisms and trade-offs between benefits and risks.
A cohort study of schools found that COVID-19-related decline in youth physical fitness persisted during the pandemic, but not associated with remote or hybrid environments. The reduction was observed in cardiorespiratory and musculoskeletal fitness healthy zone achievement.
A large cohort study found significant associations between incarceration and increased risk of death from overdoses, as well as a doubling of individual mortality risk at high county incarceration rates. The findings highlight the need for reforms in criminal justice and public health policies to address these risks.
A cohort study of 4 countries found that both maternal and paternal higher education levels were linked to reduced cognitive decline, with own education mediating these associations. The study highlights the long-term impact of parental education on offspring cognitive health across diverse cultural contexts.
A new GCAT study corrects selection biases in population-based cohorts, improving data reliability for public health research and precision medicine. The approach achieves a substantial reduction in bias, up to 70% in demographic variables and 26% in disease prevalence estimates.
A cohort study found that lower-than-recommended lead levels were associated with worse academic grades, suggesting the need to reconsider current blood lead reference values for further interventions. The findings support lowering these values to improve outcomes for children and adolescents.
Researchers identified unique symptom patterns and derived research indices for infants/toddlers and preschool-aged children, highlighting the need to characterize long COVID separately across age groups. The study provides new insights into the condition's progression in early childhood.
A large-scale genetic study identified the FOXP4 gene as a significant factor in Long COVID, linked to lung health and immune response. The study found a strong relationship between severe COVID-19 cases and Long COVID, highlighting potential biological factors contributing to the condition.
A cohort study found children on the path to obesity by age 3.5, highlighting modifiable risk factors that can be targeted in prevention programs. The Environmental influences on Child Health Outcomes (ECHO) cohort provided valuable insights into early-life factors and BMI trajectories.
A recent study published in PLOS ONE found that higher maternal selenium levels during pregnancy are associated with a lower risk of streptococcal infections in children. The research tracked over 74,000 mothers and their children to explore potential links between maternal metal exposure and infection risk.