A new Swedish twin study found that genetics largely determine an infant's crying duration, with 50% of variation explained by genes at 2 months and 70% by 5 months. Environmental factors also play a role in infants' ability to settle during the first months of life.
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Researchers from the University of Southern Denmark found that tattooed individuals are more frequently diagnosed with skin and lymphoma cancers compared to those without tattoos. The study suggests that chronic inflammation in the lymph nodes triggered by tattoo ink may lead to abnormal cell growth and an increased risk of cancer.
Research found that mothers of twins are twice as likely to be hospitalised with cardiovascular disease compared to singleton births. Those with twins and high blood pressure during pregnancy are at highest risk. However, deaths from heart disease decrease in mothers of twins compared to singletons over time.
A recent analysis found that assisted reproductive technology cycles using a gestational carrier resulted in higher live birth rates and an increased risk of twins. Despite national recommendations, more than one-quarter of embryo transfers involved two or more embryos, highlighting the need for improved guidelines.
A 20-year study by Swansea University researchers found that mothers with a history of substance misuse, smoking, or mental health conditions are at higher risk of having low-birth-weight babies. The study analyzed data from over 693,000 children born in Wales between 1998 and 2018.
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A new WVU study found nearly one in eight West Virginia infants had in utero exposure to opioids, stimulants, and/or cannabis between 2020 and 2022. The study showed a 40% increased risk of preterm birth among infants exposed to stimulants alone and a 70% increase with concurrent stimulant and cannabis exposures.
A new study has found that mothers of twins are not more fertile than other women, but rather, their increased frequency of childbirth increases the likelihood of a twin birth. The researchers used pre-industrial data from Norway, Sweden, Finland, Germany, and Switzerland to reach this conclusion.
A new study found that siblings of children with disabilities score higher in self-reported cognitive empathy than typically developing peers. This may be due to the specific 'advantage' of cognitive empathy in understanding and supporting their sibling relationship.
A systematic review of 31 clinical trials found that vaginal progesterone and 17-OHPC reduced the risk of preterm birth before 34 weeks for high-risk single baby pregnancies, particularly for women with a previous preterm birth or short cervix.
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Scientists have developed novel, non-toxic organic emitters for the near-infrared range, achieving high external quantum efficiencies in OLEDs. The new materials surpass previous reports by demonstrating improved radiative rates and reduced aggregation quenching.
Using a new combination of emitter molecules, researchers achieved devices that produce pure-blue emission with high efficiency, maintain brightness for relatively long times, and lack expensive metal atoms. The approach uses a tandem structure to effectively double the emission, leading to nearly doubled lifetime at high brightness.
Researchers at Kyushu University have developed a new material system that can directly convert visible light into ultraviolet light with an efficiency of up to 20.5%, doubling previous records. The system is promising for harnessing ambient light to drive applications requiring high-energy ultraviolet light.
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Rice University scientists have discovered a novel phenomenon in carbon nanotubes, where a delayed secondary fluorescence is emitted when triggered by a multistep process involving dye molecules and dissolved oxygen. The delay, only microseconds long, can be detected with specialized instrumentation.
Researchers at Polytechnique Montréal have created a new fluorescent organic light-emitting diode (OLED) that is 300% more efficient than existing OLEDs in its category, reaching a quantum efficiency of 3.8%. The breakthrough could enable the use of infrared OLEDs in smartphones and other devices.
Researchers at the University of the Witwatersrand have made a groundbreaking discovery in diamond, uncovering triplet spin superconductivity. This phenomenon has significant implications for the development of new technologies, including radiation detectors and advanced electronics.
Researchers found that molecular dynamics simulations confirm interactions between triplet excitons and impurities in polymer layers significantly enhance PLED efficiency. This new understanding could lead to more widespread applications of the devices in the future.
Researchers have successfully overcome the phenomenon known as lasing death in quasi-2D perovskites by managing triplet excitons. By incorporating an organic layer to hold triplets in a low energy state, continuous lasing was achieved under constant optical excitation.
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A large population study found that the risk of cerebral palsy in IVF children has consistently declined over six time-periods, from 12.5 cases per 1000 live born in 1990-1993 to 2.8 per 1000 in 2011-2014. The prevalence dropped more significantly in singletons born from IVF compared to naturally conceived children.
Researchers used a genomics tool to analyze twins' gut microbial strains before and after separating. They found that certain strains remained stable over time, even after years of living apart. The study suggests the possibility of shared microbes between non-cohabitating twins for decades.
Researchers found that two identical triplets who shared the same DNA developed Alzheimer's at different ages, suggesting other factors contribute to its development. The study also discovered that environmental and lifestyle factors can affect an individual's biological age and potentially delay or accelerate dementia onset.
A new international study has discovered epigenetic marks in Finnish twin pairs discordant for Alzheimer's disease, which were also found in brain samples of patients. These marks are influenced by environmental factors, age, gender, and APOE genotype, and have potential diagnostic applications.
The BEACON CRC Phase III clinical trial found that the three-drug combination of encorafenib, binimetinib, and cetuximab significantly improved overall survival in patients with BRAF-mutated metastatic colorectal cancer. Median OS for the triplet-targeted therapy was 9 months compared to 5.4 months for standard therapy.
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A phase III study showed that the combination of encorafenib, binimetinib, and cetuximab significantly improved overall survival (9.0 months) and objective response rates compared to standard care. The treatment was well-tolerated, suggesting a potential paradigm shift in treating BRAF-mutant metastatic colorectal cancer.
A new study found that multiple-birth infants are at a higher risk of wrong-patient order errors in the NICU, with errors between siblings accounting for most excess risk. The risk grows with increasing number of siblings, and using given names or pseudonyms can help reduce the risk
Researchers create computational models of individual patient diseases to identify diagnostic and therapeutic targets, and use T cells as a fingerprint to diagnose various diseases. The study demonstrates the potential of digital twins to improve healthcare outcomes in complex diseases.
A new combination of targeted therapies improved overall survival and objective response in patients with BRAF-mutant colorectal tumours. The BEACON CRC Phase III trial showed that triplet therapy significantly outperformed standard care, suggesting a potential replacement for chemotherapy for eligible patients.
Scientists have found a way to lower the energy required by organic light emitting diodes (OLEDs) by manipulating excitons, pairs of electrons and holes. By developing a new mechanism, researchers were able to create devices with low operating voltage.
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Researchers found highly efficient triplet pair state separation in polycrystalline films of dibenzopentalene derivatives, exceeding 100% yield. This breakthrough suggests feasibility of converting correlated singlet excited states to two free triplets efficiently for organic solar cells.
Researchers at Tohoku University and Université Grenoble Alpes have demonstrated triplet superconductivity in the uranium-based material UBe13 using high pressure and magnetic fields. This phenomenon involves electrons forming parallel spin pairs, unlike conventional superconductors where opposite spins pair together.
Research finds that female twins exposed to prenatal testosterone from a male twin are less likely to graduate from high school or college, have lower fertility rates, and earn less by their early 30s. The study supports the 'twin testosterone-transfer hypothesis' and suggests long-term biological effects on behavior and outcomes.
Researchers developed a deep-learning model that detects fake news by analyzing language patterns, finding favoritism towards exaggerations in false stories. The model achieved high accuracy in distinguishing fact from fiction, particularly when tested on novel topics.
The CRISPR Journal publishes outstanding research on all aspects of CRISPR and gene editing. Two new articles explore the ethics of germline editing and the use of alternative PAM sequences for mouse genome editing.
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Researchers at HZB integrated a thin layer of singlet fission-capable tetracene crystals into a silicon solar cell, successfully generating two pairs of charge carriers simultaneously. This breakthrough increases the quantum efficiency to 200 percent and brings the theoretical efficiency limit closer to 40 percent.
Researchers at Kyushu University have demonstrated a way to split energy in OLEDs, surpassing the 100% limit for exciton production. This new technology uses singlet fission to convert electrical charges into light with high-intensity near-infrared emission.
Researchers developed a novel electron-transport material by appending triphenyltriazine to 1,10-phenanthroline. The compound showed improved electron mobility and stability in green phosphorescent OLEDs, with high efficiency and minimal decay over time.
Researchers from Medical Research Council crack how first life on Earth replicated itself using a new type of genetic replication system. The system uses a triplet code to copy folded RNA, enabling the replication of ribozymes and supporting simple living systems.
Researchers at Kobe University have discovered a Möbius aromatic molecule that exhibits strong antiaromatic properties when exposed to light. The twist in the molecule's structure allows for high energy levels and magnetism, which could be utilized in eco-friendly organic devices such as solar cells and electroluminescent elements.
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A study found a significant link between low birth weight and left-handedness in two large sets of Japanese and Dutch newborn children. Left-handers averaged lower birth weights, with differences observed even within families.
Felix Castellano and Cédric Mongin discovered a thermally activated delayed photoluminescence mechanism in CdSe quantum dots, which can be controlled by adjusting the size of the nanoparticle and temperature. This process enables unique photoluminescent properties and could be useful for optoelectronic applications.
The separation of conjoined twins presented a complex medical challenge, requiring coordination of multiple specialists and consideration of the ethical implications. The case highlighted the importance of collaboration and compassion in providing care to vulnerable populations.
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Researchers have gained insight into how the double helix unwinds in the earliest stages of DNA replication. The new cryo-EM images show that the twin helicase enzymes load head to head, forming a complex that positions one strand for extrusion and another as the leading strand.
Researchers found higher levels of lead and lower levels of zinc and manganese in children with autism compared to those without. The study used lasers to map growth rings in baby teeth to track metal uptake during development.
The study found substantial benefits from fetal reduction, including lower rates of preterm birth and serious illness. However, the benefits were more pronounced among fertility-treated pregnancies.
Researchers at the Australian National University have identified two rare plant species, Daviesia schwarzenegger and Daviesia devito, named after the iconic movie duo. The plants are found in South Eastern Australia and are ecologically important nitrogen fixers, but are at risk of extinction due to habitat loss.
Biologists found that sets of three triplets, rather than individual codons, may be crucial for correct protein synthesis in ribosomes. This discovery could reframe cancer genetics and human genetic diseases research.
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A University of Virginia study found that married individuals tend to drink less frequently and in fewer drinks than single or divorced people. In contrast, singles are more likely to drink more often and in larger quantities. The researchers suggest that intimate relationships may provide a protective effect against excessive drinking.
A new thermally activated delayed fluorescence (TADF) material has been developed, displaying emission of light in colors from green to deep-red through intersystem crossing. This breakthrough contributes to the development of inexpensive and highly efficient OLEDs.
The US twin birth rate has surged over the last 30 years, partly due to reproductive technologies like IVF. Implementing single embryo transfer IVF could reduce unintended twin births by minimizing serious medical complications. This approach is recommended for insurance coverage and curtails the national twin birth rate.
Researchers demonstrated triplet exciton energy transfer from semiconductor nanocrystals to surface-bound molecular acceptors, extending the original excited state lifetime. This finding has implications for fields like solar energy conversion and optoelectronics.
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Researchers from KIT and CYNORA directly measured the speed of intersystem crossing in a copper complex, improving the understanding of TADF mechanisms. This leads to enhanced energy efficiency in organic light-emitting diodes (OLEDs), with potential applications in display technology.
Researchers observed entangled states in organic molecules, allowing for the control of singlet fission and potentially doubling electrical current in solar cells. The team developed a model showing that quantum dynamics play a crucial role in optimizing fission.
Children born after IVF have fewer preterm births, low birth weight issues, and stillbirths. The study found that transferring only one embryo per cycle improves single baby health.
Researchers discovered that certain peptides undergo a triplet state when exposed to UV light, leading to greater damage than fragmentation. This finding may help develop better UV protection mechanisms.
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Researchers at NIST and the University of Waterloo directly entangled three photons, a breakthrough in quantum information systems. The use of superfast single-photon detectors enabled stable and high-quality results, paving the way for applications in quantum computing and quantum communications.
Researchers at Jackson Laboratory pinpoint a new mechanism behind neurodegeneration in mice, linked to a mutation in the tRNA gene n-Tr20. The study reveals that individual tRNA genes can be tissue-specifically expressed, leading to disease or modifying phenotypes.
A new study found a possible genetic link between cerebral palsy and family ties, with increased risks seen in twins, first cousins, and closer relatives. The study identified a stronger recurrence rate among co-twins of affected children and families with an affected single child.
Researchers have discovered that naturally occurring gatekeeper sequences on either side of a key protein mutation in Huntington's disease can prevent the formation of toxic structures. This breakthrough offers new hope for understanding and treating the devastating neurodegenerative disorder.
New research estimates that over a third of twin births and three-quarters of triplets in the US are caused by fertility treatments. Non-IVF fertility treatments have increased to become the leading cause of medically assisted multiple births, while IVF is now often producing twins.
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Research from Bispebjerg University Hospital in Denmark found that women with asthma took longer to conceive compared to those without. The study revealed a higher proportion of prolonged time to pregnancy among asthmatic women, particularly those with untreated asthma.
Pregnancies with twins or higher-order multiple births cost significantly more due to increased maternal morbidities, cesarean sections, and neonatal intensive care. Strategies to minimize multiple embryo transfer are recommended to reduce the burden associated with multiple pregnancies.