This study evaluated the combined effects of epidural electrical stimulation (EES) and physical therapy (PT) on sensory, motor, and autonomic functions in SCI patients. EES+PT significantly enhanced long-term sensory function, muscle strength, spasticity, and urinary function compared to PT alone.
Researchers at NC State University have developed origami robots that can navigate the body using magnetic 'muscles.' These robots can deliver medicine to ulcers without reducing surface area, enabling a safe and non-invasive procedure. The technique allows for controlled and steady drug release over time.
A team of researchers has developed a tiny, spider-inspired robot that can navigate the digestive system with ease, delivering therapy precisely where it's needed. The soft robot overcomes challenges faced by traditional endoscopes, showcasing its adaptability in traversing complex environments.
Physician Organization of Michigan ACO (POM ACO) has achieved significant savings for Medicare by reducing unnecessary spending and focusing on preventive care. The organization's efforts saved Medicare nearly $35 million in 2024, with members sharing in the $17 million incentive.
A new study reveals an unusual microbial world in the Hatiba Mons hydrothermal vent fields, showcasing remarkable metabolic versatility. The microbes present demonstrate a unique ecosystem dominated by iron-driven metabolisms, which drive chemical transformations and sustain life under extreme conditions.
A randomized clinical trial found that colchicine did not improve functional capacity or inflammatory markers in adults with long COVID. Researchers highlight the need for new therapeutic strategies for this condition.
A new study demonstrates the safety and tolerability of enteral ventilation in a first-in-human trial, using rectal delivery of perfluorocarbon liquid. The researchers aim to improve oxygen levels in patients with blocked airways or severely limited lung function.
An international team has discovered 30 novel fungal lineages using eDNA long-read sequencing techniques, shedding light on the unknown diversity of eukaryotic organisms. The researchers developed innovative taxonomic approaches to describe and communicate these unseen microeukaryotes.
A new one-shot federated learning AI technique has been developed to combine privacy protection and efficiency in medical image analysis. The technique increases training data diversity, reduces overfitting, and eliminates unnecessary computation, achieving higher accuracy with fewer computations.
Researchers at University of California San Diego have developed an AI-based method to target cancer stem cells, which can spread and resist therapy. The approach leverages machine learning to identify treatment targets and restore function to genes, leading to the self-destruction of cancer cells.
A new quantum-secured data transmission architecture has been proposed to address the challenges of AI-driven data centers. The system achieves terabit-per-second capacity while defending against future quantum threats through self-homodyne coherent transmission and integrated quantum key distribution.
Researchers have confirmed that six North American bat species emit a greenish light when exposed to UV rays, suggesting it may be an inherited trait used for communication. The study's findings could provide valuable insights into how bats adapt in the past and to future environmental changes.
Sing Sing Way has made significant contributions to understanding the immune system's response to pregnancy, maternal-fetal dyad, and immunity in newborn babies. He is recognized for his outstanding professional achievement and commitment to service, bridging fundamental biology and translational medicine.
Researchers discovered manganese's unique ability to act as a catalyst when electrical voltage fluctuates, making it suitable for applications like wind and solar energy. Manganese's regeneration under the Guyard reaction enables its use over repeated cycles, crucial for sustainable reactions.
A new virtual reality training task has been developed to help stroke survivors living with visuospatial neglect, a disabling condition affecting attention and awareness of one side of space. The VR task incorporates interactive exercises and audiovisual cues to engage patients and support rehabilitation.
Researchers identified a set of biomarkers that can predict blood pressure outcomes five years after adolescents underwent metabolic bariatric surgery. The study found that blood-based biomarkers were more accurate than traditional risk factors, suggesting a potential new approach to predicting long-term blood pressure outcomes.
A new study led by NYU Langone Health researchers shows that almost 70% of focal epilepsy patients, considered treatment resistant, experience a reduction in their average monthly seizure frequency over three years. The study found that even those who respond poorly to initial therapies may eventually see improvement.
Researchers found that hydrothermal systems release iron that can be transported far beyond vent sites through environmental parameters and plume chemistry. This process has significant consequences for ocean productivity and the global carbon cycle.
Research challenges assumption that severe preeclampsia cases are more dangerous for mothers, finding instead that women with large preterm infants face increased cardiovascular disease risk despite smaller infant size.
The US needs a new strategy for insurance coverage and access to cell and gene therapies due to high up-front costs. In contrast, Europe has approved 19 CGTs with most being reimbursed within two years of approval based on demonstrated added therapeutic value.
Researchers track expansion of disease-carrying mosquitoes and their hybrids in North America, particularly in Utah. Climate change and land use changes enable mosquitoes to thrive in new areas, spreading West Nile Virus and other mosquito-borne illnesses.
Electron behavior in solid materials has been puzzling scientists, but a new study reveals that energy alone is not enough for them to escape. The discovery of doorway states explains why different materials exhibit unique behaviors despite similar electron energy levels.
Engineers at the University of Pittsburgh have created a soft material with a nerve net that mimics how simple living systems coordinate motion. The material responds to chemical reactions, producing mechanical movement without electronics or motors.
Researchers revive dark matter as a serious contender for explaining the Milky Way's central glow, proposing a more complex and nonspherical dark matter structure. Advanced simulations reveal that dark matter may still be the best explanation for the excess of high-energy radiation observed by NASA's Fermi Gamma-ray Space Telescope.
Researchers at Columbia University Irving Medical Center have discovered new vulnerabilities in the malaria parasite's PfATP4 sodium pump, which could lead to more effective treatments. The study also identified a previously unknown binding partner essential for parasite survival.
A study published in the Lancet Child and Adolescent Health journal found that high-risk neuroblastoma survivors experience a high prevalence of hearing loss, growth failure, underweight, and lung disease due to modern therapies. Longer follow-up periods were associated with a higher risk of late effects.
A new study suggests the traditional United Nations index for judging countries' manufacturing power can produce misleading results. A revised model uses advanced data analysis to benchmark countries against realistic standards, providing a clearer picture of global industrial competitiveness.
A new study found that storytelling strategies with conceptual or perceptual details activate distinct brain networks, predicting how well participants recall core elements of the story. This suggests that people's preferred memory systems may vary across age groups, and tailored information could improve memory for older adults.
DGIST researchers develop innovative manufacturing process for high-performance permanent magnets, overcoming conventional limitations. The new technology creates uniform magnetic performance throughout the magnet, enabling miniaturization and weight reduction in electric vehicle motors.
Recent advances in perovskite thin-film patterning techniques are crucial for high-performance optoelectronic devices. The research team introduces dimensional engineering, correlating material performance and structural dimensionality across different scales.
Scientists at Tel Aviv University have identified a protein called Tfii-i that inhibits myelin production, and found that reducing its activity increases myelin output. This discovery may lead to innovative treatments for conditions such as multiple sclerosis, Alzheimer's disease, and autism spectrum disorders.
Researchers found that combining zanzalintinib, a targeted therapy drug, with atezolizumab, an immune checkpoint inhibitor, improved survival rates by 20% compared to standard treatment regorafenib. The new combination also delayed cancer progression and showed promising results in patients with metastatic colorectal cancer.
A new study from Karolinska Institutet and UCL found that living in a safe neighborhood with high personal trust reduces psychosis risk among Swedish or European origin residents, but increases it for North African or Middle Eastern origin individuals. The researchers emphasize the need for inclusive environments to promote mental heal...
Researchers discover that gray hair may be a result of a natural defense mechanism against cancer, where damaged stem cells undergo senescence-coupled differentiation, leading to graying. In contrast, bypassed stem cells can expand clonally and lead to tumor development.
A research team at the University of Münster has developed a new measurement method that combines fluorescence microscopy with MALDI mass spectrometry imaging, revealing metabolic differences in tumors. This allows for faster and more precise diagnoses and targeted therapies.
Researchers have developed a novel therapeutic approach that combines difluoromethylornithine with a targeted diet to enhance the effectiveness of treatment in high-risk neuroblastoma patients. The diet blocks the formation of polyamine precursors, amplifying the drug's effects and driving cancer cells to mature.
Christopher Chen, a renowned biomedical engineer, has been elected to the National Academy of Medicine for his groundbreaking contributions to cell and tissue engineering. His research may lead to lifesaving new treatments for disease, including heart attack cures and organ repairs.
A new study finds that adverse and positive childhood experiences reported by parents of US teenagers have remained relatively stable over the past eight years. Positive childhood experiences were significantly more common than negative ones, affecting 40-90% of parents, whereas only 35% of adolescents experienced all negative experien...
Researchers propose using the Agent Deed Consequence (ADC) model to program ethical values into smart city technologies. The model captures human moral judgments by considering agent intent, deed, and consequence, enabling AI systems to distinguish between legitimate and illegitimate orders.
Scientists at the University of Surrey have discovered a simple way to boost sodium-ion battery performance by leaving water in key component. The new material, nanostructured sodium vanadate hydrate, showed significant improvements in charge storage, charging speed, and stability, even in saltwater.
Astronomers detected complex organic molecules in ices outside the Milky Way for the first time, finding five different carbon-based compounds, including methanol and acetic acid. This discovery sheds light on how chemical ingredients for life spread throughout the cosmos.
A recent study found that fish oil supplements can lower cardiovascular disease risk even in healthy individuals, with effects varying greatly between people. The study showed that EPA supplementation improved blood lipid profiles and reduced lipoprotein attachment to arterial walls.
Researchers found that 1% penciclovir cream is safe and well-tolerated when used to treat feline herpesvirus type 1-related eye infections. The cream maintained antiviral levels for over eight hours, suggesting twice-daily use could effectively manage the condition.
A research team at the Medical University of Vienna has discovered a previously unknown mechanism that plays a decisive role in the development of pre-eclampsia. The study found that an amino acid transporter and transcription factor work together to control angiogenesis and protect cells from oxidative stress.
Researchers found that brain mechanisms for spatial attention differ when processing mental images from memory versus visuals on a screen. When recalling imagery, frontal areas are more active, suggesting distinct mechanisms for spatial attention in mental imaging.
Researchers are building an AI-powered database of MRI and CT images to track disease progression and measure patient response to treatments. The database will provide a standardized toolkit for extracting precise imaging biomarkers, enhancing the accuracy of organ measurements and improving treatment choices.
Researchers from Xi'an Jiao Tong University develop on-skin epidermal electronics for next-generation wearable devices that overcome traditional wearables' limitations. This technology enables long-term, high-fidelity health monitoring with innovative design features.
UT Dallas researchers are developing a material to protect spacecraft from atmospheric drag and erosion, which can damage vehicles in space. The new coating has shown promising results, withstanding atomic oxygen conditions better than those in space.
A wireless retinal implant has been shown to restore central vision in patients with advanced age-related macular degeneration (AMD), with 81% of participants achieving clinically meaningful improvements in visual acuity. The device converted light into electrical signals, stimulating remaining retinal cells and restoring visual inform...
A new study published in JNeurosci used fMRI to investigate how the brain acquires semantic information. The results suggest that the quality of activity in distinct brain regions can predict whether people successfully acquire knowledge about places and characters in fictional civilizations.
A new MIT study found that a theta-frequency brain wave scans the mental image and a region of the cortex maps visual information. The researchers observed that performance depends on the phase of this wave when the changed square appears, and the vertical location on the screen of that target square.
Christina Economos, dean of the Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University, has been elected a member of the National Academy of Medicine for her pioneering research on childhood obesity prevention and her commitment to evidence-based innovations in pursuit of better health outcomes.
A clinical trial found that a subretinal implant partially restored sight in over 80% of participants with age-related macular degeneration (AMD), enabling them to read letters, numbers, and words. The device demonstrated significant benefits, including improved visual acuity and letter recognition.
Scientists at the German Primate Center discovered that the brain reorganizes itself to control motor prostheses in a virtual environment. The findings suggest that different regions of the brain jointly reflect corrected movement commands, rather than separate components for expected results and error signals.
Lehigh University researchers used machine learning to compare bone marrow extracted from the hip and shoulder, finding six proteins that distinguish between the two extraction sites. This study may lead to standardized BMAC extraction protocols and personalized treatments based on protein concentrations.
Researchers found that ATG9A helps prevent inflammation by promoting autophagy-mediated cleanup of inflammatory proteins in skin cells. This mechanism limits TNF-driven STING activation and ZBP1-dependent cell death, preventing severe skin disease.
Researchers found that AI-generated content is a triple threat to Reddit moderators, posing concerns over decreasing content quality, disrupting social dynamics, and being difficult to govern. To address these issues, moderators are enacting rules and trying to preserve the community's humanity.
A new study from the University of Kansas found that football practices can be up to 40% more physically demanding than games, with defensive backs running farther distances. The research used GPS technology to measure training loads and provide insights for coaches and trainers to design optimal practice schedules.
A new study published in The Lancet Healthy Longevity found that current NHS policies to improve care for people taking multiple medicines may not be effective. Researchers tested a new process involving rigorous medication reviews by pharmacists and GPs, but found no improvement in safe prescribing compared to usual care.
Researchers found a targeted immunotherapy regimen yielded promising survival outcomes for patients with B-cell ALL, outperforming historical results. The treatment was well-tolerated, with more than half completing the full course of therapy, and responded similarly in patients with complex medical histories.