A new study found that reinforcing natural daily rhythms improves sleep and brain waste clearance after a stroke, leading to better outcomes. The researchers tested various interventions targeting the body's internal clock and found promising results in mouse models of stroke.
Researchers have developed a new chip that can analyze light on the spot, detecting subtle differences in materials and environments. This technology has the potential to support real-world applications without bulky external equipment.
A new study by Uppsala University researchers shows that internet-based CBT can significantly reduce symptoms of stress and anxiety in women with broken-heart syndrome, a condition often triggered by extreme stress. The treatment also helps patients better cope with emotions related to their illness.
A large-scale European study found that screening people with Li-Fraumeni syndrome can significantly reduce healthcare costs. The study showed that prevention costs per patient were roughly nine times lower than treatment costs, and patients who underwent regular screening had better clinical outcomes.
The International Society for Stem Cell Research announces the launch of a global consortium focused on integrating human stem cell-derived models into preclinical drug development. Bayer is a founding member, aiming to establish standardized frameworks and regulatory guidance for these models.
A University of Barcelona team has produced a biodegradable bioplastic, polyhydroxybutyrate (PHB), using a modified bacterium. PHB can be produced in a single 24-hour step from unprocessed potato starch, reducing dependence on oil and plastic waste.
Observing resilient coworkers can boost performance and well-being, but also lead to anxiety if employees feel they can't replicate the same level of resilience. To make stories of resilience motivational, it's essential to highlight how the individual is similar to other employees.
Researchers propose a thermochemical mantle plume formation process for the Ontong Java Plateau, contradicting previous hypotheses. The model explains spatial variations in crustal thickness and lava composition across the plateau.
A new review reveals that spinal cord injury can trigger a cascade of systemic complications throughout the entire body, affecting organs far from the original injury site. The authors propose a neuro-immune-metabolic network framework for understanding these complications and suggest a shift towards proactive, system-wide recovery.
Astronomers have detected the [O I] 145 µm emission line in four typical star-forming galaxies, which serves as a clear tracer of neutral gas. This detection provides unprecedented detail on the physical and chemical conditions of star-forming material in these distant galaxies.
Researchers discovered a sun-like star TOI-5882 with unusually high lithium concentrations, suggesting it has consumed a planet in the past. The team used spectroscopy to analyze light from the star and compared its results to control stars, finding that TOI-5882's lithium content is among the highest ever observed.
Scientists at Tohoku University have developed a new sample-preparation technique called gradient blotting, allowing for the observation of materials in their native liquid environments. This breakthrough extends cryo-electron microscopy beyond water-based systems, enabling the study of materials under realistic processing conditions.
A new study reveals that plants actively redirect sugars to damaged tissues, concentrating glucose around the injury site. This process fuels the regeneration process and helps plants recover from physical damage or environmental stress.
Adults with prediabetes who undergo lifestyle intervention show a lower burden of multimorbidity compared to those not receiving the intervention. Lifestyle programs can persistently reduce the development of chronic conditions in this population.
A team of researchers has developed a zinc oxide material that exhibits strong and highly sensitive mechanoluminescence without using rare-earth elements. The material combines high sensitivity with low cost, making it suitable for various applications such as biomedical sensors and infrastructure monitoring.
The report highlights the clinical, emotional, and societal impact of psychosis in individuals living with Alzheimer's disease. Nonpharmacologic strategies are recommended to identify triggers and tailor interventions, with pharmacologic options considered when behavioral strategies are insufficient.
A robotic pet rabbit named Mía has been developed to recognize users by their voice, allowing for personalized affective stimulation in elderly care. The system uses a unique 'voice signature' that adapts to each user's speech patterns, enabling the robot to respond differently to various individuals.
A new UMaine study identifies strategies to make outdoor education accessible to all schools, highlighting the importance of community support and collaboration among staff. The research builds on previous work by Lauren Jacobs, who examined successful models in rural Maine schools.
A study of 165,832 women found that later menarche is associated with an increased risk of tobacco use disorder and various conditions, including digestive issues, heart problems, and brain disorders. The researchers suggest a shift in perspective to recognize childhood influences as the primary cause of adult health problems.
A recent study found that bilingualism is driven by a common neural system that works across languages, contradicting the idea of separate grammar engines. This neural mechanism supports grammar in English and Spanish, indicating that human language may be built from universal computations.
Research at Ohio State University found that just 10 viral particles can cause H5N1 avian flu infection in cows. The study also suggests that the virus has an affinity for cow mammary glands rather than airways.
The American Heart Association's Primary Care Perspectives platform provides practical education and tools to identify cardiovascular, kidney, and metabolic risk factors connected to heart failure. This initiative aims to improve long-term outcomes and reduce preventable disease progression by supporting earlier identification and mana...
A study found that tirzepatide significantly increases brown adipose tissue activity and volume in premenopausal women with obesity. The medication also shows potential signs of converting white subcutaneous fat into more metabolically active 'beige' fat.
The review systematically maps out the research landscape of wearable AI doctors, combining power-harvesting approaches with self-powered intelligence. Flexible electronics enable devices to withstand dynamic environments, while on-device AI inference processes data locally for real-time analysis.
A viscoplastic interlayer composed of PIB and MAPP effectively seals non-planar electrodes, preventing biofluid ingress. The interlayer's conformal contact and tight binding block water permeation, ensuring long-term stability.
A new method analyzes AI models' learned features to group materials by structural and spectral similarity, revealing key factors influencing material properties. This approach opens up new possibilities for designing materials with specific and useful properties.
Researchers successfully reconstructed the evolution of the virus-human interaction over the course of an entire pandemic. They identified that strong selection pressure leads to rapid emergence of highly contagious variants, similar to Omicron. This study offers hopes that scientists may predict how viruses evolve in the future.
A study found that the spring SAM underwent a marked structural shift around 1998, strengthening its delayed influence on Antarctic summer sea ice. This shift led to enhanced ice-loss processes, including increased air-sea heat exchange and ocean warming in the Weddell Sea.
Researchers have discovered that plant viruses can deliver CRISPR RNA guides to plants, enabling targeted genome edits. The study showcases the potential of potyvirus-based systems for expanding crop genome editing.
A new study found that a class of oral and intranasal medications known as gepants may be an effective treatment for vestibular migraine. Gepants work by blocking calcitonin gene-related peptide (CGRP), which drives migraine attacks, providing relief from dizziness and vertigo.
A study of 585 older adults found that different patterns of depressive symptoms are associated with disability-free survival, differing between men and women. Stronger feelings of 'worthlessness' were a significant risk factor for men, while 'anxiety' was a bigger risk factor for women.
Researchers have identified a deep Earth dynamic mechanism responsible for the formation of widely distributed seamounts. The study extends and refines the classical mantle plume model by pinpointing asthenospheric thermal anomalies as key factors in generating volcanic activity.
The phase 2 ImmunoPRISM trial shows teclistamab significantly improves outcomes for patients with high-risk smoldering multiple myeloma. The BCMA-targeted bispecific antibody outperformed lenalidomide plus dexamethasone, pointing to the potential value of using immune-based therapy earlier in the course of the disease.
Researchers at Okayama University of Science have successfully cultivated juvenile chum salmon in a land-based aquaculture system using third water. The project aims to establish fully closed-cycle aquaculture, which could fundamentally change the future of salmon production and contribute to long-term sustainability.
Citizen science data from iNaturalist has helped uncover the evolution of parental guarding behavior in harvestmen, doubling the number of documented cases. The study found that paternal care evolved independently, while maternal care followed a pattern seen in insects.
Researchers at KAIST have developed a new nano-printing technology that allows for the transfer of ultra-fine metal circuits onto plant leaves, fruits, curved automotive surfaces, and robot exteriors without causing damage. This technology has vast potential for applications in smart agriculture, wearable healthcare, and bioelectronics.
Researchers have developed a computational design technology that utilizes computer simulations to analyze and predict the scaling limits of transistors. The technology identifies the quantum tunneling limit, which varies depending on the type of metal and contact structure.
Researchers used AI agents to compile data on 31,028 licensed greyhounds, uncovering a 30% increase in on-track fatalities between 2022 and 2024. The study also revealed the high turnover of greyhounds has not changed, with around 40% stopping every year.
A team of researchers from the Weizmann Institute of Science has developed a new approach to detecting alien biology, leveraging statistical patterns in molecular diversity. By analyzing groups of molecules rather than individual ones, the method can identify biological signatures even in samples with limited information.
Researchers used snRNA-seq to study H2S signaling in Chinese cabbage, identifying 18 clusters of cell types and 9 major cell types. The study found that H2S induces globally coordinated transcriptional reprogramming and identifies two key genes enhancing drought tolerance.
A recent study identified CaBZR1.2 as a key player in regulating lateral branch growth in peppers, while CaSnRK1β2 acts as an opposing factor. This regulatory balance may help determine the fate of axillary buds and provide insights into crop architecture.
Researchers at Nagoya University developed an AI tool, DiSPAH, to estimate ALS disease progression speed and identify muscle decline patterns. The study found six distinct patterns of disease progression among patients, with some experiencing rapid deterioration while others declined slowly.
Nucleosome assembly protein Nap1 safeguards genome integrity by regulating chromatin dynamics and guiding nuclear division. Its deletion disrupts cellular processes, leading to structural aberrations and genomic instability.
A new study identifies a feed-forward loop involving PpnGATA8, PpnGRF5, and PagXTH9 that helps convert polyploid gene dosage into enlarged leaf cells. This regulatory module explains how polyploid gene dosage may be translated into larger leaf cells, stronger photosynthesis, and more vigorous vegetative growth in poplar.
Scientists successfully demonstrated reversible topological phase transitions in β-Ag2Te using out-of-plane gate voltages. This breakthrough enables the creation of functional electronic components with high current on-off ratios, overcoming previous hurdles in practical application.
A two-year fixed-duration triplet therapy of pirtobrutinib, venetoclax, and rituximab improves progression free survival for patients with relapsed/refractory CLL compared to standard therapy. Peripheral blood undetectable minimal residual disease rates are higher in patients receiving the triplet therapy.
A study published in Psychological Medicine found that a laxative drug, Prucalopride, improved executive function and memory in patients with depression. The research suggests that targeting serotonin receptors may help alleviate cognitive problems associated with depression.
A global study confirms mosquito nets reduce malaria cases by up to 68%, but highlights regional variations and the need for locally adapted control strategies. The researchers warn that relying on ITNs alone may not be enough, especially in areas with established insecticide resistance.
Researchers have found a potential new treatment for DHDDS-related disease by creating mini-brains from patients' cells and testing vitamin B3. The study showed significant improvements in patients' symptoms, including reduced tremors and increased energy levels.
A large-scale study found dozens of genetic mutations linked to cancer type and ancestry, improving survival predictions in breast and glioma cancers. Combining ancestry data with tumour analyses enhances prediction accuracy, particularly for pancreatic cancer patients.
Researchers found a copper-based compound significantly reduces toxic Alzheimer's proteins and improves long-term spatial memory in laboratory experiments. The treatment repairs the brain's waste-clearing pump, allowing it to clear out trapped toxic proteins and reduce amyloid buildup by 42%.
A retrospective cohort study found that menopausal hormone therapy significantly reduces the risk of low bone mineral density by 69% compared to non-users. This suggests that hormone therapy could be an effective way to prevent bone loss and lower fracture risks in women after menopause.
A study presented at ENDO 2026 found semaglutide was associated with a 15% reduction in bone fractures and greater weight loss compared to other anti-obesity medications. The results suggest that semaglutide may have beneficial effects on bone health in people with type 2 diabetes.
A study found that nearly 4 in 10 patients stopped GLP-1 medication within the first year and nearly two-thirds restarted therapy within two years. The researchers also identified sociodemographic, clinical, and provider-level predictors of discontinuation, including Medicaid or Medicare status, Black patients, and side effects.
The first real-world study of fezolinetant found the treatment improved hot flashes, depression, and anxiety in women with menopausal vasomotor symptoms. In a study of 656 women, fezolinetant significantly reduced hot flash symptoms and showed benefits similar to those seen in clinical trials.
Researchers found that certain genetic variants increase the risk of steroid side effects, particularly osteoporosis and stroke. Integrating polygenic risk scores into steroid prescribing can improve risk assessment and identify patients at high risk, allowing for closer monitoring or alternative treatments.
A study presented at the Endocrine Society's annual meeting found that exposure to the plasticizer DEHP in early development can lead to increased anxiety-like behavior in adult male rats. The research suggests that humans exposed to endocrine disruptors before and shortly after birth may experience long-lasting behavioral changes.
A study of 336 mother-infant pairs found that breast milk and infant urine contained over 50 different chemicals, including BPA and phthalates, which can interfere with hormones during baby's development. These chemicals were detected in breast milk and urine up to 6 months after birth.
A nationwide study of over 5.7 million women aged 40 found a link between longer reproductive spans and an increased risk of thyroid cancer. The research also showed that hormone replacement therapy, especially for five years or more, was associated with a higher risk of developing the disease.
The study found a significant increase in type 1 diabetes cases among Hispanic/Latino adolescents in Puerto Rico, from 10.1 per 100,000 in 2009 to 24.1 in 2021, with an average annual increase of 4.1%. This trend has important implications for patient care and public health.