A new study by Stanford Medicine investigators found that biological age of organs can predict disease risk and longevity. The researchers used a blood-based indicator to assess the age of 11 organ systems, including brain, heart, and lungs, and found strong associations between these ages and various diseases.
Injectable peptides marketed online for enhancement purposes are raising concern due to lack of regulation and limited research. The use of these substances is blurring the line between legitimate treatment and enhancement use, complicating enforcement and creating uncertainty for clinicians, regulators, and consumers alike.
Researchers have developed a direct one-step synthesis of cyclohexanone cyanohydrin using nitrogen, methane, and cyclohexanone under mild conditions. The new method achieves high selectivity, yield, and formation rate, offering a new strategy for efficient utilization of inert small molecules.
Researchers developed a new biomaterial that forms faster and is more durable than natural blood clots, with potential applications in traumatic injuries and emergency medicine. The engineered clots can support tissue healing and reduce inflammation, offering great potential for wound healing and trauma care.
Researchers have identified a protein called cathepsin B that can prevent CAR T-cells from tearing off fragments from cancer cells, allowing them to stay active longer and fight cancer more effectively. This breakthrough could lead to improved durability and outcomes for patients with recurrent or difficult-to-treat blood cancers.
Researchers identified four genomic regions associated with longevity genes and found 12 rare protein-altering genetic variants that might influence longevity. One of these variants mapped to the CGAS gene, which is involved in producing an inflammatory response when DNA detects damage.
A new study by researchers from the Institute of Atmospheric Physics at the Chinese Academy of Sciences reveals that reforestation has varying effects on water resources under different warming scenarios. Under low-warming conditions, reforestation slightly increases global water but widens the gap between wet and dry regions. In contr...
A new study reveals that honeybees can evaluate the reliability of their communication and adjust their dance vigor accordingly. Bees with verified, honest information increase their recruitment effort over time when advertising a new location, while unverified bees do not.
WSU researchers found that every 1% increase in tax burden leads to a 4.3% decrease in corruption convictions, suggesting citizens care more about government when they pay more taxes
A new meta-analysis from the University of Georgia found tirzepatide to be the most effective GLP-1 medication for weight loss in non-diabetic patients, achieving over 20% weight reduction. Semaglutide and liraglutide were less effective, with weight losses of 15% and 8%, respectively.
A recent study analyzing 5.8 billion medicines dispensed in England from 2019 to 2024 found significant health disparities, with nearly twice as many medicines prescribed to the most deprived groups as those in the least deprived groups by age 40.
Researchers found that CAR T cell therapy triggers a broad immune response in glioblastoma patients, with activated natural killer cells associated with better outcomes and longer overall survival. In contrast, high levels of immunosuppressive regulatory T cells and myeloid cells hinder the therapy's effectiveness.
Biomedical and veterinary laboratories in Benin were found to have severe deficiencies in staff training, standard experimental practices, and emergency preparation. The study's findings highlight the need for localized biosafety codes, regular tiered training, and improved lab infrastructure to enhance pathogen containment.
The technology clarifies its core advantages over traditional manufacturing methods and provides a roadmap for future development.
Dietary supplement use among US adults increased from 1999 to 2023, with diversification towards immune, anti-inflammatory, and joint health products. Older adults saw a substantial increase in supplement use, highlighting the need for ongoing monitoring of public health implications.
A new study suggests that students need to understand three threshold concepts: writing with AI is experimental, requires human expertise, and ultimately augments human agency. By learning to try, test, and tinker with AI tools, students can develop the skills needed to write effectively in an AI-driven world.
Researchers studied the South Pole-Aitken (SPA) basin on the Moon's far side, a massive impact structure that may have excavated material from deep inside the lunar mantle. Advanced models and simulations recreated the SPA-forming impact, identifying new evidence about the direction and composition of the object that struck the Moon.
Researchers at the University of Vienna have achieved a breakthrough in molecular editing, enabling the direct transformation of complex structures without rebuilding. This method opens up new possibilities for modern drug research, allowing for the simple testing of hundreds of variant molecules.
Half of parents track their adult kids' locations occasionally, with 1 in 4 saying it increases anxiety. While tracking provides reassurance, constant access to information can also fuel anxiety and blur the lines between safety and privacy.
Clinical trials suggest that GLP-1s can improve testosterone levels and sperm quality in men with obesity-related low testosterone. The research also found that GLP-1s address the underlying effects of obesity on fertility. The studies showed no negative impact on hormones, sexual function, or sperm quality.
Researchers developed a designable van der Waals crystal that mimics the functions of human neurons and synapses using light. The device demonstrates key synaptic functionalities and achieves high accuracy in edge detection and image recognition tasks.
Avi Goldfarb, a University of Toronto marketing professor, has received the INFORMS Society for Marketing Science Fellow Award for his long-term contributions to the field. He is recognized for his research on the economics of digital technology and artificial intelligence.
A local research study found that only a minority of tested DNA switches were active in living liver tissue, with many linked to genes involved in metabolism and immune responses. The activity of these switches shifted in response to changes in the gut microbiome.
Research reveals that gaming fans' passionate critiques are a sign of deep brand loyalty and can drive consumer advocacy. The study found six distinct dimensions of brand advocacy, including Brand Positivity and Brand Defence, which are key to building genuine fan communities.
A Danish study reveals that financial compensation alone is insufficient to persuade landowners to restore low-lying soils as wetlands. The decision-making process is influenced by factors such as responsibility, professional pride, and attachment to the land, highlighting a mismatch between policy design and farmers' actual thoughts.
Southwest Research Institute has patented EZ Flow technology, which reduces the viscosity of heavy crude oil by 40-60%, making it easier and less expensive to transport. The two-part process uses a proprietary chemical additive and controlled hydrodynamic cavitation to reduce viscosity without changing the oil's composition.
Research in mice and human heart cells suggests that synthetic cooling agents in e-cigarettes can disrupt heart rhythm, causing abnormal beats and increased cardiovascular risk. The study's findings have implications for policymakers reviewing current rules on coolants used in vapes.
A new review article argues that forensic anthropology has been hindered by outdated and harmful methods that perpetuate a male/female binary. The authors call for sex-expansive practices that reflect human biocultural variation and affirm LGBTQIA+ livelihoods.
A new model of conformity excels in real-world data, disregarding outliers to produce more accurate results. The researchers tested the model against various scenarios and found it superior to the French-Harary-DeGroot model in many cases.
PhD candidate Tommaso Zaccaria's research shows that microorganisms from Earth can survive in Martian hot springs and other celestial bodies. This has implications for astronaut health and the study of the human immune system on Earth.
Differences were observed in parent and child mealtime media use patterns among racial and ethnic groups. Black parental race was positively associated with paired use, while Asian parental race was associated with individual use.
The American College of Physicians recommends semaglutide and tirzepatide as first-line treatments for nonpregnant adults with obesity, while recommending lifestyle modifications including improved nutrition and physical activity. The guideline also emphasizes discussing benefits, harms, costs, and contraindications with patients.
Researchers studied plant responses to heat at the molecular level, finding PIF4 acts as a control switch for temperature-induced growth responses. The protein's ability to team up with other proteins could inform future efforts to develop heat-resistant crops.
A study reveals how tree crown structure affects competitive interactions in forests, with light-demanding species experiencing slowed growth near neighboring trees with different crowns. Shade-tolerant species show more flexible crown forms and are limited by nearby conspecifics, aligning with the Janzen Connell hypothesis.
A new study reveals that obesity is reshaping the global cardiovascular disease crisis, with heart disease now peaking in people aged 50-54 rather than the elderly. The study projects over 1.37 million premature cardiovascular deaths attributed to obesity by 2050, primarily in South Asia and low-income countries.
A new study published in KeAi journal Landscape Architecture and Sustainability demonstrates that virtual reality-based mindfulness meditation with EEG biofeedback can significantly enhance concentration, relaxation, and emotional well-being among university students. The VR audiovisual-EEG interactive meditation environment produced t...
The study uses smartwatch data to record how match events affect fans' heart rate and stress levels. Fans from Eastern and Southern Europe and Turkey are underrepresented, so the research team aims to include as many participants as possible.
Avishek Choudhury, a WVU researcher, has won the NSF CAREER award to study how healthcare providers' trust in artificial intelligence changes over time. His goal is to humanize algorithms behind AI and improve decision-making quality and patient safety.
A new clinical trial is investigating the efficacy of psilocybin-assisted therapy for persistent post-concussion symptoms. Researchers expect the drug to reduce neuroinflammation and enhance neural connections, with benefits lasting at least six months post-treatment.
Urban parks are found to have a significant impact on mitigating heat, air and noise pollution in cities, extending far beyond their boundaries. Parks with tree cover and grassland areas improve thermal comfort and reduce Physiologically Equivalent Temperature by up to 8.5°C.
A University of Michigan study finds that North America has sufficient rare earth element deposits to support a domestic supply chain, but most are of lower quality than those in China and Australia. The US could prioritize light rare earth elements and cooperate with Canada on heavy ones.
The Critical Path Institute's Type 1 Diabetes Consortium is strengthening regulatory science and evidence frameworks for disease-modifying therapies. The expanded C-peptide evidence base supports ongoing evaluation of the biomarker as a drug development tool.
Researchers at Indiana University are using artificial intelligence and machine learning to discover new treatments for Alzheimer's disease. The team hopes to create AI-driven tools that can efficiently screen billions of compounds and prioritize those most likely to interact with disease-related targets.
A study found that 18% of college students used AI for mental health, with those having more severe symptoms and Asian students being more likely to do so. The use of AI may pose risks, such as undermining emotional regulation or perspective-taking.
The proposed National Lunar Research Center (NLRC) will simulate the Moon's surface and test lunar base infrastructure on SwRI grounds. The initiative aims to accelerate research and development for NASA's Artemis Moon Base and prepare a specialized workforce.
A new immunotherapy combination has shown promise in delaying cancer progression and improving survival for patients with multiple myeloma. The study found that nearly nine in 10 patients receiving the treatment experienced a shrinkage of their cancer, compared to about eight in 10 on standard treatment.
Researchers developed a two-pronged approach to encourage important conversations between patients with cancer and their oncologists about goals and preferences for care. The study found that combining reminders for both patients and providers at the right moment significantly increased serious illness conversations.
Researchers suggest that the evolution of toxin accumulation in poison dart frogs occurred gradually, with at least four phenotypes representing stages in this process. These phenotypes include species that sequester alkaloids or modify them, while others metabolize toxins without accumulating them.
A new study suggests that migratory predators can act as evolutionary messengers, carrying avoidance behaviors across continents and linking the fates of species separated by thousands of kilometers. This challenges a longstanding assumption in mimicry theory, opening up a hidden world of long-distance evolutionary relationships.
The report documents Singapore's journey and approach toward urban heat resilience, examining a sustained, multi-stakeholder response. It identifies six key dimensions of a coordinated response, including high-level political commitment, science partnerships, and community empowerment.
Klick Labs is launching a series of clinical studies with Mayo Clinic exploring the use of novel vocal biomarkers in connection with Type 2 diabetes, hypertension, ovulation, and blood glucose. The research collaboration aims to leverage the voice's hidden properties to flag critical health issues and enhance patient care.
A study analyzing 21 pairs of wild red-crowned cranes found three specific behavioral elements: bill-stab, bow, and arch. The sequence and timing of these elements play a crucial role in pair communication, with males dancing longer than females and females taking the lead in determining dance content.
Machine learning models trained on brief clinical conversations identified cognitive impairment with high accuracy, supporting passive speech-based screening during routine primary care. The study's findings suggest a feasible and non-invasive method for early detection of cognitive decline.
Researchers develop Ru@Bi/N-C catalyst for electrocatalytic hydrogenation of lignin, achieving 93.64% conversion and selective cleavage of lignin linkages. The catalyst-electrolyte synergistic strategy enables efficient biomass valorization.
A new fluorescence imaging-based technique allows researchers to measure individual scramblase protein activity rates, revealing new findings and broad applicability. This enables precise study of key scramblases and their potential role in various biological processes and diseases.
Dr. Jennifer Guida, a renowned researcher and program director, has been appointed as the first director of HonorHealth Research Institute's Division of Institutional Research. She will oversee the institute's clinical trials efforts, providing patients with pioneering treatments based on internal research discoveries.
Scientists have developed a framework combining multiscale reservoir ecological operations, ecological flow reconstruction, and innovative irrigation techniques to balance ecological sustainability with socioeconomic demands. The approach has successfully revitalized ecosystems in China's Tarim and Irtysh River Basins, offering lessons...
Scientists at the University of Osaka developed a theoretical framework to explain the anomalously large magnetic susceptibility of organic radical fluids. They found that dynamic magnetic interactions during molecular collisions enhance the magnetic susceptibility, explaining the phenomenon beyond conventional theories.
New studies reveal potential for 30-day forecast accuracy boosts using machine learning and explore the impact of vegetation on ocean currents during the Little Ice Age. Researchers also find that La Niña events can slow global warming by amplifying each other's cooling effects.
A new study suggests that moderate sitting may be beneficial for highly active adults, contradicting previous guidelines. The research found a J-shaped association between daily sitting time and health outcomes, with the lowest risk at approximately 4 hours of sitting per day.