A study found that children with autism spectrum disorders (ASD) and attention deficit hyperactivity disorder (ADHD) exhibit more gender variance, a wish to be the other gender, than their typically developing peers. The study also revealed higher rates of anxiety and depressive symptoms among these children.
The American Academy of Child and Adolescent Psychiatry has revised key parameters for evaluating and treating autism, emphasizing early diagnosis and a team approach to care. Researchers led by Fred Volkmar recommend a coordinated medical, psychological, and communication evaluation to differentiate between autism and other disorders.
Researchers detected atypical development in nearly half of the younger siblings of children with autism by 12 months. The study found that many of these children showed delays in social, communication, cognitive, or motor development, particularly in social-communication domains.
The Gordon & Llura Gund foundations have donated $3 million to Autism Speaks to support the Autism Ten Thousand Genomes program, sequencing over 3,000 genomes. This gift will enhance the organization's research and technology networks, leading to real-life medical impacts on individuals and families.
A new study from Autism Speaks found that a multipronged approach is needed to assess children for autism, increasing early detection rates. However, challenges remain, including limited follow-up care and shortages of specialists and therapy programs.
A new study found that combining autism with social communication disorder (SCD) would decrease estimated prevalence under DSM-5 criteria. The researchers discovered that 83% of children diagnosed with autism under the DSM-IV would also receive the diagnosis under DSM-5, while 14% were diagnosed with SCD.
A new report from the National Professional Development Center on Autism Spectrum Disorders identifies 29 evidence-based practices for children and youth with autism, including technology-aided instruction and exercise. These practices can help reduce costs and improve outcomes for individuals with autism.
The grants will focus on reducing the average age of diagnosis, increasing access to high-quality early intervention and understanding environmental risk factors for autism. Researchers will also develop effective treatments and assess the benefits of early interventions in urban settings.
A Kaiser Permanente study found that hospital-diagnosed maternal bacterial infections during pregnancy were associated with an increased risk of autism spectrum disorders in children. The study included 407 children with autism and 2,075 matched children who did not have autism.
A new study published in Cell journal strengthens the understanding that gut microbes can affect brain function and behavior, particularly in individuals with autism spectrum disorder. Feeding mice a beneficial type of bacteria has been shown to reduce autism-like behaviors.
Researchers at Caltech found that altering gut bacteria can improve autism-like behaviors in mice, reducing GI problems and improving communication and social interactions. The probiotic treatment corrected a 'leaky' gut characteristic associated with autism.
A study by USC scientists found that air pollution exposure amplifies the risk of developing autism spectrum disorder in children who carry a genetic variant associated with the disorder. The research, published in Epidemiology, suggests that gene-environment interactions play a significant role in autism risk.
A single dose of oxytocin has been shown to temporarily normalize brain regions responsible for social deficits in children with autism. The hormone facilitates social attunement, allowing brain regions involved in social behavior and cognition to activate more for social stimuli.
A novel approach to treating autism spectrum disorder teaches affected children to control their autonomic nervous system using computerized biofeedback and clinical hypnosis. The method recognizes symptoms as an effort to self-regulate inner turmoil, allowing children to feel better and be more socially engaging.
A large Danish study of over 600,000 children found no significant link between antidepressant medication during pregnancy and the risk of autism. After adjusting for parental psychiatric diagnoses, the researchers determined that taking antidepressants during pregnancy does not further increase the risk of autism.
A Yale-led team identified common neural circuits affected by autism-risk genes and when they exert their effects on the developing human brain. The findings suggest new targeted treatments for autism may be possible, focusing on specific neural circuits at specific times.
Researchers recorded individual nerve cells in the amygdala of patients with high-functioning autism and found a specific type of neuron responding abnormally to the mouth region. The study provides new insights into mechanisms underlying autism symptoms and opens the door for further studies.
Researchers found that boys with autism who had access to screens in their bedrooms spent less time sleeping. Video-game exposure was also linked to reduced sleep among the boys with ASD. The study highlights the need for parents to monitor and limit screen use before bedtime for children with autism.
A study found that synaesthesia occurs in 18.9% of people with autism, compared to 7.2% of typical individuals. The researchers suggest that both conditions involve neural over-connectivity, leading to atypical connections between brain areas.
A new study by the UC Davis MIND Institute found that children with autism are six-to-eight times more likely to have gastrointestinal problems, including constipation, diarrhea, and sensitivity to foods. These symptoms are related to behavioral issues such as social withdrawal, irritability, and repetitive behaviors.
Researchers identified declining attention to others' eyes in infants later diagnosed with autism, starting from 2 months old. This finding has profound implications for early intervention strategies and suggests that interventions could build on existing levels of eye contact.
Researchers have identified a steady decline in attention to others' eyes in 2-6 month old infants later diagnosed with autism. This finding suggests that social engagement skills are intact shortly after birth in children with autism, and could lead to early diagnosis and treatment.
Research suggests that depressed levels of insulin-like growth factor (IGF) may be a biomarker for autism occurrence. Breastfeeding could serve as a natural source of IGF, potentially lowering the risk of autism development.
The Weatherstone Fellowship program supports the development of rising talent in autism research, providing critical resources for building early careers. The five 2013 recipients will work directly with mentors and collaborate with others to share knowledge and experiences.
Researchers found an association between autism spectrum disorder risk and prenatal weight gain, after accounting for important related factors. The study suggests that weight gain during pregnancy may serve as an important marker for autism's underlying gestational etiology.
A study led by researchers at Mount Sinai found that individuals with autism were more likely to have gene deletions than those without the disorder, which may contribute to miswiring of brain neurons. The study suggests that these deletions could impact genetic testing and have clinical significance.
A team of scientists has developed a process to connect an autism-linked gene to its function. They found that mutations in the NHE9 gene cause communication problems among brain cells, contributing to autism. The study used a step-wise strategy to screen variants and identified changes that affect endosomal pH, altering cell traffic.
A study by UC Davis MIND Institute found that none of the children with 22q11.2 deletion syndrome met strict diagnostic criteria for autism. Evaluations should be performed to assess autism and guide therapy selection based on symptoms such as language delay.
A study by Oregon State University researchers found that autistic toddlers and preschoolers with better motor skills were more adept at socializing and communicating. Motor skills development is crucial for social skills, and the study highlights the importance of addressing this deficit in early interventions.
Two studies found that young adults on the autism spectrum have worse employment outcomes, including lower pay rates, and are less likely to live independently after high school. Despite this, half of young adults with ASDs did become employed, suggesting potential for improvement with effective preparation and support.
Researchers at the Seaver Autism Center will test Insulin-Like Growth Factor-1 (IGF-1) in children with Phelan-McDermid Syndrome, a severe type of autism. IGF-1 has shown preclinical promise in reversing nerve cell communication deficits and restoring learning and memory abilities.
The Rhode Island Consortium for Autism Research and Treatment (RI-CART) has received a $1.2 million grant to create a confidential registry of individuals diagnosed with autism in the state. The registry aims to improve diagnoses and treatments by connecting families with clinical experts and researchers.
A new study published in the Journal of the American Academy of Child and Adolescent Psychiatry demonstrates support for the DSM-5 symptom structure for toddlers with autism spectrum disorder. The researchers found that the DSM-5 model was a better fit to the data than other models used during toddler assessment.
The estate of Charles Meixner has donated $3 million to Autism Speaks, supporting translational postdoctoral fellowships and research into autism spectrum disorder. The gift will contribute to the development of new treatments and improve the lives of individuals and families affected by ASD.
A new study reveals that autism affects the brain of females and males differently, with females showing 'masculinization' in atypical brain areas. This finding suggests a need to re-evaluate research methods and understanding of autism's neurobiology.
Researchers found that moving attention fluidly and orienting to social information are not key components of autism. Children with high-functioning autism and those without autism showed similar signatures in shifting attention and responding to social stimuli.
The Rhode Island Consortium for Autism Research and Treatment (RI-CART) brings together researchers, physicians, scientists, service providers, educators, and parents to collaborate on research, education, and advocacy projects. The consortium aims to improve the lives of Rhode Islanders with autism spectrum disorders by promoting coll...
A collaborative effort by Autism Speaks has found full genome sequencing examining the entire DNA code of individuals with autism spectrum disorder (ASD) and their family members. The study identified genetic variations associated with risk for ASD, including de novo, X-linked, and inherited DNA lesions in four new genes.
A new study using whole genome sequencing identifies 19% of deleterious de novo mutations and 31% X-linked or autosomal inherited alterations in autism spectrum disorder. The findings also reveal genetic variants in several risk genes, including CAPRIN1, AFF2, VIP, SCN2A, KCNQ2, NRXN1, and CHD7.
A Vanderbilt research program trains community pediatricians to diagnose autism, leading to a significant increase in diagnoses within their practices. The training improved diagnostic accuracy and shifted the comfort level of discussing ASD diagnoses with caregivers.
Researchers have identified a specific risk factor for autism, known as MAR autism, linked to maternal antibodies attacking fetal brain proteins. The study found that mothers of children with autism were more than 21 times likely to have these antibodies, offering a potential biomarker for drug development and early diagnosis.
Researchers found that infants with later-diagnosed autism had excessive cerebrospinal fluid and enlarged brains, raising the possibility of using these as potential biomarkers. These anomalies were detectable by MRI at 6-9 months and remained elevated between 18-24 months.
A new study published in Adapted Physical Activity Quarterly found that children with autism who struggled with motor skills such as catching and throwing had more severe social and communication skills. Developing motor skills can be crucial for children, enabling them to participate in physical activities and socialize with peers.
Autism Speaks has committed nearly $199 million to research projects aiming to advance understanding of autism causes, prevention, treatment, and cure. The organization supports six translational postdoctoral fellowships focusing on brain studies, sleep patterns, and social cues in individuals with autism.
A new study from SDSU found that autism affects a broad range of sensory and motor systems, not just social abilities. The research suggests that the diagnostic criteria for autism may fail to consider the full spectrum of problems children with autism experience.
The collaboration aims to lower the average age of diagnosis from four to five years to six to 12 months in the African American community. Autism Speaks will provide materials and guidance to churches and parents on recognizing signs of autism and accessing services.
A study published in PLOS ONE found that children with autism have higher levels of gluten antibodies than those without autism. The researchers also discovered an association between the elevated antibodies and gastrointestinal symptoms in affected children. However, no connection was found to celiac disease.
A new study from Harvard School of Public Health found that women exposed to high levels of air pollution while pregnant were up to twice as likely to have a child with autism. The study examined data from over 116,000 nurses and found associations between air pollution and autism risk in children.
A Northwestern University study found that male offspring of rat mothers who were given alcohol during pregnancy exhibit social impairment and altered levels of autism-related genes. Low doses of thyroid hormone thyroxin reversed social impairments and expression of these genes, suggesting a potential treatment target for both disorders.
A new rodent study found that Fetal Alcohol Spectrum Disorders and Autism Spectrum Disorder share common molecular vulnerabilities. Low-dose thyroxin treatment appears to alleviate some effects of alcohol exposure on offspring. The study suggests a potential biochemical marker for identifying children at risk for ASD.
Researchers from the Seaver Autism Center at Mount Sinai identified common clinical symptoms of Phelan-McDermid Syndrome, including severe to profound intellectual disability, seizures, and low muscle tone. The study provides important guidance for developing a standardized assessment methodology for this disorder.
Researchers found individuals with autism spectrum disorders have significantly decreased metabolism of amino acid L-tryptophan, leading to potential early blood screening tests. The study also identified genes involved in L-tryptophan metabolism, paving the way for therapeutic options.
BIDMC's Dennis P. Wall has developed a new method to diagnose autism in young children quickly and accurately, enabling rapid online assessments. This approach has shown promise in clinical environments, with the potential to improve early diagnosis and treatment outcomes.
A new study found that children with autism perceive motion twice as quickly as their peers, suggesting a fundamental cause for the developmental disorder. This heightened sensitivity to motion may contribute to painful sensory experiences and complex social and behavioral deficits.
The Autism BrainNet network will acquire, process, store, and distribute brain tissue resources to accelerate understanding of the biological basis of autism. The network aims to broaden the reach of existing brain donation programs, expanding access to research for scientists and families affected by autism.
Researchers from the University of Manchester have found that babies born with abnormal fetal growth are at a higher risk of developing Autism Spectrum Disorder. The study analyzed data from over 40,000 child health records in Sweden and found that larger or smaller babies were more susceptible to autism.
Researchers at Yale University have discovered a key marker to identify newborns at risk for autism: abnormal placental folds and cell growths called trophoblast inclusions. This breakthrough allows for earlier diagnosis and treatment, potentially improving outcomes.
A study published in JAMA found that maternal use of valproate during pregnancy significantly increases the risk of autism spectrum disorder and childhood autism in offspring. The absolute risk is estimated at 4.42% for autism spectrum disorder and 2.50% for childhood autism.
Researchers at the University of Missouri found that propranolol improves working memory performance in people with Autism Spectrum Disorder. The study showed significant improvements in working memory abilities, particularly in those who already take the medication for anxiety.
Research found that mutations in neuroligin-3 protein block endocannabinoid signals, affecting brain excitability and communication between neurons. The study suggests targeting the endocannabinoid system may help reverse autism symptoms.