Researchers found that young breast cancer patients who received a low-dose radiotherapy boost had a lower risk of local recurrence after 10 years, with only 4.4% experiencing recurrence. In contrast, high-dose boosts resulted in fewer recurrences but also more severe fibrosis and cosmetic issues.
SourceEuropean Organisation for Research and Treatment of Cancer·TypeRandomized controlled/clinical trial·DateMar 20, 2024
A new review by UMass Amherst researchers highlights the need for more research on breast cancer cell dormancy, which is a contributing factor to metastatic breast cancer. The study aims to identify gaps in research and develop better models to understand and treat this phenomenon.
SourceUniversity of Massachusetts Amherst·JournalScience Advances·TypeLiterature review·DateMar 19, 2024
Researchers at the University of Adelaide have discovered a new approach to defeating breast cancer by stimulating the androgen receptor. The study found that enobosarm was effective against estrogen receptor-positive breast cancer, which is the most common form of the disease.
SourceUniversity of Adelaide·JournalThe Lancet Oncology·TypeRandomized controlled/clinical trial·DateFeb 11, 2024
A recent study published in The BMJ found that women diagnosed with ductal carcinoma in situ (DCIS) outside the NHS breast screening programme are four times more likely to develop invasive breast cancer and die from breast cancer. The increased risk lasts for at least 25 years after diagnosis, suggesting longer-term monitoring is needed.
SourceBMJ Group·JournalThe BMJ·TypeObservational study·DateJan 24, 2024
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A groundbreaking study identifies FAM3C as a key regulator of breast cancer progression within the tumor microenvironment. The overexpression of FAM3C promotes breast cancer cell survival and metastasis, while its depletion inhibits tumor growth in genetically engineered mouse models.
SourceUlsan National Institute of Science and Technology(UNIST)·JournalCancer Research·DateJan 19, 2024
Researchers found that p53-mutated breast cancer cells reprogram fat cells to create an inflammatory microenvironment, impairing the immune response against the tumor. This interaction drives cancer growth and is a key driver of tumor-promoting reprogramming of fat cells.
SourceGerman Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)·JournalProceedings of the National Academy of Sciences·DateJan 3, 2024
Cancer-associated fibroblasts in the brain secrete fucosylated poliovirus receptor that stimulates breast cancer migration and invasion. The researchers hope these findings will help develop better diagnostic and therapeutic approaches for breast cancer brain metastasis patients.
SourceH. Lee Moffitt Cancer Center & Research Institute·TypeExperimental study·DateDec 14, 2023
A study published in JAMA Oncology found that regular screening is not enough to prevent advanced breast cancer diagnoses, particularly among women of color who are overweight or obese. The researchers recommend primary prevention strategies to reduce the number of advanced cancer diagnoses.
SourceUniversity of California San Francisco Medical Center·JournalJAMA Oncology·TypeData/statistical analysis·DateDec 7, 2023
The Susan G. Komen organization presents awards to four dedicated physician scientists and a pioneering research advocate for their contributions to advancing breast cancer research and transforming patient care. Dr. Olufunmilayo Olopade and Dr. Daniel Hayes are recognized for their work in basic science and clinical research, respecti...
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A new study found that frequency and content of clinician-patient breast density discussions varied by women's race, ethnicity, and literacy levels. Women from different racial and ethnic groups reported varying experiences in discussing their breast density with clinicians.
SourceBoston University School of Medicine·JournalJAMA Network Open·TypeSurvey·DateNov 27, 2023
A new ASTRO clinical guideline recommends partial breast irradiation as a viable alternative to whole breast radiation for patients with early-stage invasive breast cancer or DCIS, based on evidence from large randomized trials. The guideline provides guidance on patient selection and best practices for delivering effective partial bre...
SourceAmerican Society for Radiation Oncology·JournalPractical Radiation Oncology·DateNov 15, 2023
Researchers have discovered that genetic ancestry influences the biology of normal breast tissue and how it factors into the development of aggressive breast cancers. PZP cells, naturally higher in Black women, can influence cancer cell behavior and growth.
SourceIndiana University School of Medicine·JournalNature Communications·DateOct 25, 2023
Breast milk from breast cancer patients contains tumour DNA that can be detected through liquid biopsy, offering a potential new tool for early diagnosis. The study found that ctDNA was detectable in 13 of 15 breast milk samples collected from breast cancer patients, outperforming detection in blood samples.
SourceVall d'Hebron Institute of Oncology·JournalCancer Discovery·DateSep 14, 2023
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
A study published in Radiology found that combining short- and long-term breast cancer risk models using artificial intelligence can improve cancer risk assessment. The combined model showed an overall improved risk assessment for both interval and long-term cancer detection, identifying women at high risk for breast cancer.
SourceRadiological Society of North America·JournalRadiology·DateAug 29, 2023
Women with low-risk breast cancer aged 55 or older can be effectively treated without radiation after surgery, according to new research published in The New England Journal of Medicine. A total of 2.3% of patients experienced recurrence of cancer in the breast five years post-surgery.
SourceMcMaster University·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateAug 16, 2023
A Kaiser Permanente study found that drinking alcohol after a breast cancer diagnosis does not impact a patient's prognosis. The research used data from over 4,500 women diagnosed with invasive breast cancer and tracked their lifestyle changes and outcomes over 11 years.
A machine learning model found that background parenchymal enhancement (BPE) on breast MRI is an indicator of breast cancer risk in women with extremely dense breasts. Women with dense breasts are at a higher risk of developing breast cancer compared to those with fatty breasts.
SourceRadiological Society of North America·JournalRadiology·DateAug 8, 2023
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
Researchers found that breast cancer survivors experience a faster rate of biological aging, with higher rates of age-related diseases and physical cognitive decline. Radiation therapy was found to be particularly impactful on aging rates, contributing to the conversation on how to best treat and care for breast cancer survivors.
SourceH. Lee Moffitt Cancer Center & Research Institute·TypeSurvey·DateJul 19, 2023
Researchers found that healthy breast adipocytes secrete IGFBP2, which acts as a barrier against invasive breast cancer progression. Lower IGFBP2 levels with age may contribute to increased breast cancer risk.
SourceUniversity of Turku·JournalScience Advances·DateJul 13, 2023
Inflammatory breast cancer is a rare and aggressive form of breast cancer with poor outcomes. Research highlights the role of ERβ as a mediator of estrogen signaling, demonstrating its tumor suppressive effects in preclinical models. ERβ's antimetastatic activity may hold promise for improving treatment options for IBC.
SourceImpact Journals LLC·JournalOncotarget·TypeCommentary/editorial·DateJul 3, 2023
Research suggests that aromatase inhibitors can limit the effectiveness of weight loss medications in breast cancer survivors. Studies have shown that these medications are less effective in women taking aromatase inhibitors, leading to reduced weight loss and increased risk of health complications.
A study published in The BMJ found that women diagnosed with early stage breast cancer today can expect to become long term cancer survivors. The average risk of dying from breast cancer in the five years after a diagnosis has fallen from 14% to 5% since the 1990s.
SourceBMJ Group·JournalThe BMJ·TypeObservational study·DateJun 13, 2023
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
A recent study published in the journal CANCER found that supplemental ultrasound screening can detect breast cancers missed by mammography, but it requires careful targeting of high-risk groups. Women with dense breasts are at higher risk of interval invasive breast cancer, and clinicians should consider other breast cancer risk facto...
Researchers developed a method to predict DCIS progression to invasive breast cancer using mice with human DCIS cells. The study found molecular similarities between humans and mice, including the presence of HER2 protein increasing breast cancer risk.
SourceNetherlands Cancer Institute·JournalCancer Cell·TypeExperimental study·DateMay 3, 2023
A study published in Radiology found that AI can analyze breast mass images from low-cost portable ultrasound machines and accurately identify cancer. The technology showed great promise for improving breast health care in low-resource settings, reducing delays in diagnosis and potentially saving lives.
SourceRadiological Society of North America·JournalRadiology·DateMay 2, 2023
Researchers at Indiana University School of Medicine have identified a new target for breast cancer treatment, the gene TONSL, which can make breast cells proliferate indefinitely. The study found that TONSL is amplified in about 20% of breast cancers and more than 30% of metastatic breast cancers.
SourceIndiana University School of Medicine·JournalCancer Research·DateApr 20, 2023
A new deep learning-based model estimates breast density with high precision, correlating it to cancer risk. The model's performance is comparable to that of human experts, but it can be trained faster and on smaller datasets.
SourceSPIE--International Society for Optics and Photonics·JournalJournal of Medical Imaging·TypeExperimental study·DateApr 7, 2023
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
A study published in Radiology found that ultrasound is an effective standalone diagnostic method for patients with focal breast complaints. The analysis showed that ultrasound alone led to accurate diagnosis in 90% of patients, with over 80% of complaints being benign findings.
SourceRadiological Society of North America·JournalRadiology·DateApr 4, 2023
A large study of over 1 million women found DBT had a higher breast cancer detection rate and lower false positive rates compared to 2D digital mammography. The results suggest that DBT may be the more effective screening method for early breast cancer detection.
SourceRadiological Society of North America·JournalRadiology·DateMar 14, 2023
Researchers at the Institute of Cancer Research discovered that molecular changes in lung tissue can trigger breast cancer cells to 'reawaken' and form secondary tumors. They found that blocking PDGF-C activity with an existing cancer growth blocker could help prevent this, offering a potential strategy to defuse these 'time bombs'. Th...
SourceInstitute of Cancer Research·JournalNature Cancer·TypeExperimental study·DateMar 13, 2023
A new study suggests that radiotherapy does not improve survival rates in older breast cancer patients with early-stage breast cancer. The 10-year study found that adding radiotherapy to breast-conserving surgery and hormone therapy did not increase death rates among patients aged 65 or older.
SourceUniversity of Edinburgh·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateFeb 15, 2023
Awareness of breast density increases perceived risk and uncertainties about screening choices in Spanish-speaking women. However, these effects are short-term and do not persist over time, suggesting that educational outreach may help clarify implications for personal risk and screening decisions.
SourceColumbia University's Mailman School of Public Health·JournalBreast Cancer Research·DateFeb 2, 2023
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
Researchers from HKUMed discovered that somatic deletion of AKTIP promotes luminal breast cancer development and resistance to endocrine therapy. Blocking the alternative escape pathway with a JAK2/STAT3 inhibitor can overcome this resistance, offering new therapeutic possibilities for patients with AKTIP gene deletion.
SourceThe University of Hong Kong·JournalCell Reports·TypeExperimental study·DateFeb 2, 2023
A meta-analysis of 22 studies found that breast MRI was superior to other supplemental screening methods in detecting breast cancer in women with dense breasts. This is because breast MRI can detect even the smallest of cancers, making it a valuable tool for identifying high-risk patients.
SourceRadiological Society of North America·JournalRadiology·TypeMeta-analysis·DateJan 31, 2023
Medical College of Wisconsin scientists have identified PD-L2 as a therapy-relevant marker for predicting early recurrence of breast cancer. High levels of PD-L2 protein in cancer cells are associated with an elevated risk of progression and may indicate patients who can benefit from immunotherapies such as PD-1 inhibitors.
SourceMedical College of Wisconsin·JournalJournal of Clinical Oncology·DateJan 25, 2023
Patients with two or three sites of breast cancer in the same breast who underwent lumpectomy and radiation therapy had local recurrence rates comparable to those with a single tumor. Breast MRI was found to improve detection of additional disease sites, potentially allowing for more thorough resection.
SourceAmerican Association for Cancer Research·DateDec 9, 2022
Younger breast cancer patients who paused endocrine therapy to pursue pregnancy experienced similar short-term rates of breast cancer recurrence as those who continued therapy. The study found that many women were able to conceive and deliver healthy babies, with conception and childbirth rates comparable to the general public.
SourceAmerican Association for Cancer Research·DateDec 8, 2022
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Researchers have identified a protein that can predict how well breast cancer patients will respond to chemotherapy. Increasing levels of this variant p53 makes breast cancer cells unresponsive to existing therapies, highlighting its potential as a target for enhanced treatments.
SourceHunter Medical Research Institute·JournalCell Death and Disease·TypeExperimental study·DateNov 22, 2022
A large observational study found that women diagnosed with benign breast disease through screening are at a higher risk of developing breast cancer in the long term. The risk persisted for at least two decades and was found to be significantly higher among women with benign breast disease compared to those without.
SourceEuropean Organisation for Research and Treatment of Cancer·JournalInternational Journal of Environmental Research and Public Health·TypeObservational study·DateNov 17, 2022
A 30-year follow-up study of patients with early breast cancer found that radiotherapy does not improve overall survival rates after 10 years but reduces the risk of recurrence in the same breast. The study's findings challenge traditional concepts of long-term anti-cancer benefits of radiotherapy.
SourceEuropean Organisation for Research and Treatment of Cancer·TypeRandomized controlled/clinical trial·DateNov 17, 2022
A study by Leiden University Medical Center found six proteins in blood samples that were altered one to two years before a breast cancer diagnosis. The researchers believe these proteins could be used to develop a blood test for early detection of breast cancer in high-risk women.
SourceEuropean Organisation for Research and Treatment of Cancer·TypeObservational study·DateNov 16, 2022
A new model predicts individual breast cancer risk based on ten known risk factors, allowing for tailored screening strategies. The study found that the risk of developing breast cancer ranges from 0.22% to 7.43%, with some factors, such as exercise, having a greater impact than previously thought.
SourceEuropean Organisation for Research and Treatment of Cancer·TypeObservational study·DateNov 15, 2022
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
A study published in the Journal of the National Comprehensive Cancer Network found that breast cancer survivorship has doubled among Canadian women, with 2.1% of adult females diagnosed with breast cancer and 86% surviving by 2022. The prevalence varies by age group, with senior women having a higher rate of survival.
SourceUniversity of Toronto·JournalJournal of the National Comprehensive Cancer Network·TypeData/statistical analysis·DateNov 3, 2022
A USC-led team has found indications for an early breast cancer detection method using high-definition liquid biopsies. The test detected multiple cancer biomarkers, including 'oncosomes,' in the blood samples of most early-stage breast cancer patients.
SourceUniversity of Southern California·Journalnpj Breast Cancer·TypeRandomized controlled/clinical trial·DateSep 28, 2022
Research from UVA Cancer Center finds that an unhealthy gut microbiome can trigger changes in normal breast tissue, facilitating cancer's spread to other parts of the body. The study suggests that targeting the gut-mast cell relationship could help prevent breast cancer recurrence and metastasis.
The Montefiore Einstein Cancer Center has received a $10 million grant from the National Cancer Institute to study lung metastasis in breast cancer. The research aims to understand the mechanisms of tumor cells seeding tumors in the lungs, a key site for triple-negative breast cancer metastasis.
A recent study found that background parenchymal enhancement (BPE) at surveillance breast MRI is independently associated with an increased risk of future second breast cancer. Women with dense breasts and minimal BPE may no longer need to undergo contrast-enhanced breast MRI every year if other risk factors are absent.
SourceRadiological Society of North America·JournalRadiology·DateAug 30, 2022
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
Researchers at Queen's University Belfast have secured a £228,900 grant to develop an mRNA vaccine targeting protein p53 in triple negative breast cancer. The project aims to improve treatment options for patients with this aggressive form of the disease.
A new study found an inverse association between breast cancer risk and n-3 PUFA consumption, especially in premenopausal women who are obese. Higher intake of marine n-3 PUFAs and total n-3 PUFAs was associated with a lower risk of breast cancer.
SourceThe Menopause Society·JournalMenopause·TypeMeta-analysis·DateJul 27, 2022
A large cohort study found that hormone replacement therapy for breast cancer survivors is not associated with an increased risk of recurrence. The study included over 8,400 Danish postmenopausal women and found no link between vaginal estrogen or menopausal hormone therapy and breast cancer reoccurrence.
SourceOxford University Press USA·JournalJNCI Journal of the National Cancer Institute·TypeData/statistical analysis·DateJul 20, 2022
The NHS Breast Screening Programme is associated with modest overdiagnosis of breast cancer, estimated at 3.7% of screen detected cancers. However, the benefits of screening in preventing deaths from breast cancer outweigh this risk, according to a recent study.
SourceQueen Mary University of London·JournalCancer Medicine·TypeObservational study·DateJul 18, 2022
Research from RCSI University of Medicine and Health Sciences found a link between high von Willebrand Factor levels and poorer breast cancer outcomes. High levels in the bloodstream can increase the risk of life-threatening blood clots and cancer spread in patients.
SourceRCSI·JournalJournal of Thrombosis and Haemostasis·DateJun 30, 2022
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Researchers at Baylor College of Medicine have identified a potential more effective treatment for HER2 mutant metastatic breast cancer, poziotinib. The drug reduced tumor growth and multi-organ metastasis in laboratory tests and animal models.
SourceBaylor College of Medicine·JournalCancer Research·TypeExperimental study·DateJun 23, 2022
A new study suggests that probiotic bacteria, particularly Lactobacillus, may enhance the effectiveness of tamoxifen and other endocrine-targeted therapies in reducing ER+ breast cancer risk. The researchers found elevated levels of Lactobacillus in breast tissue of mice treated with tamoxifen, leading to decreased breast tumor formation.
SourceThe Endocrine Society·JournalJournal of the Endocrine Society·DateJun 11, 2022
A recent study by McMaster University researcher Timothy Whelan and his team has identified a specific group of patients with early stage breast cancer who can effectively treat their disease with just surgery and endocrine therapy. The study found that the recurrence of cancer in these patients was just 2.3% without radiotherapy.
SourceMcMaster University·TypeRandomized controlled/clinical trial·DateJun 7, 2022
Research describes how breast cancer cells impair pancreatic islet function to suppress insulin production, leading to diabetes and increased tumor growth. The study identifies microRNA-122 as a key player in this process.
SourceUniversity of California - San Diego·JournalNature Cell Biology·DateMay 30, 2022
Sky & Telescope Pocket Sky Atlas, 2nd Edition
Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.
A landmark trial found that a widely used diabetes drug, metformin, is not effective against the most common forms of early-stage breast cancer. However, researchers discovered a potential benefit for individuals with HER2-positive breast cancer, which accounts for about 20% of all breast cancers.
SourceLunenfeld-Tanenbaum Research Institute·JournalJAMA·TypeRandomized controlled/clinical trial·DateMay 24, 2022
A large study published in Radiology found that women with dense breast tissue and benign breast disease are at increased risk of developing breast cancer. The study, which included over 3.9 million Korean women, suggests that these women may benefit from supplemental screening with MRI or ultrasound.
SourceRadiological Society of North America·JournalRadiology·DateMay 17, 2022
A recent study published in Breast Cancer Research suggests that self-reported male infertility may be associated with an increased risk of invasive breast cancer. The researchers conducted a case-control study among 1,998 males diagnosed with breast cancer, comparing them to 1,597 control males without blood relatives. The study found...
SourceBMC (BioMed Central)·JournalBreast Cancer Research·DateMay 16, 2022
A new study suggests that while breast density knowledge may be increasing due to existing state laws, there is still room for improvement. The study found that most women with non-dense breasts did not correctly know their own density, and that lower education was associated with a lower chance of accurately knowing one's own density.
SourceDartmouth Health·JournalJournal of the American College of Radiology·TypeSurvey·DateApr 25, 2022