Researchers have successfully generated large numbers of virus-resistant immune cells from monkeys using CRISPR/Cas9 gene editing. This breakthrough could lead to the development of a new treatment for HIV/AIDS by providing an alternative to current therapies that require lifelong medication and can cause side effects.
A new wireless implant has the potential to treat neuropathic pain resistant to medical therapy, offering a minimally invasive alternative to surgery. The device uses bioelectronic therapy to stimulate peripheral nerves from within blood vessels, providing precise placement and predictable outcomes.
Researchers at the University of South Australia have developed a novel approach to rubber recycling that repurposes end-of-life tyres into concrete for residential constructions. The study found that crumb rubber concrete is a safe, green alternative with higher impact resistance, toughness, and ductility compared to conventional conc...
A new study by researchers from the Annenberg Public Policy Center finds that exposure to alternative health media can affect beliefs about consequential health-care issues like vaccination. After Dr. Mehmet Oz endorsed the MMR (measles-mumps-rubella) vaccine on a March 2019 episode of “The Dr. Oz Show,” significantly more people in hi...
Researchers at Mayo Clinic have developed a new antibody test to diagnose multiple sclerosis (MS), a potentially disabling disease of the brain and spinal cord. The validated test measures kappa immunoglobulin free light chains in cerebrospinal fluid, offering a faster and more cost-effective alternative to existing tests.
A study found that 42% of TikTok videos on high blood pressure focused on alternative medicine, while only 5% mentioned exercise. Most creators were not healthcare professionals, highlighting the need for more emphasis on credible sources.
A University of Alberta study found that environmentally aware consumers are more inclined to buy insect- or algae-fed chicken if provided with information about its health and environmental benefits. Consumers who received nutrition facts on the packaging were more likely to purchase the alternative product, while those without this i...
A non-antibiotic alternative, methenamine hippurate, has been shown to be as effective as antibiotics in preventing recurrent urinary tract infections. The study found that women taking this drug experienced a lower rate of UTI episodes compared to those on daily antibiotics.
A recent study by SMU Associate Professors Mark Chong and Angela Leung found that the ultimate form and presentation of alternative protein products significantly impact their acceptance by consumers. Focusing on the end product and framing alternative proteins as a positive highlight of an exciting food future may foster greater accep...
Researchers analyzed 60 billion tweets to understand vaccine hesitancy on social media. They found that anti-vaxxer profiles often share links to YouTube videos and commercial sites selling alternative health products, highlighting the spread of misinformation in echo chambers.
A new model estimates India's actual COVID-19 death toll could be as high as 3.2-3.7 million, surpassing other reported figures. This revised estimate aims to address the issue of underreporting and provides a more accurate representation of the pandemic's impact on India.
Researchers have created an environmentally friendly packaging material from apple waste, offering a potential alternative to plastic. The new material is made from apple pomace and has improved water resistance thanks to the incorporation of polymers and compounds.
A Rutgers study found that hospital patients with repeated negative RT-PCR tests but exhibiting COVID-19 signs and/or symptoms were half as likely to receive treatment as those who tested positive. The study suggests that clinicians should not solely rely on RT-PCR tests for COVID-19 diagnosis.
Magnesium-based batteries offer a promising alternative to lithium-ion batteries, with several significant advantages. However, developing cost-effective and high-performance batteries requires further research on electrolyte development, anode design, and cathode structure.
A novel molecular mechanism underlying the orange-fruited phenotype of tomato has been discovered through a new study. The gene SlIDI1 is found to produce both long and short transcripts simultaneously, which are involved in carotenoid biosynthesis.
Researchers from Korea Maritime & Ocean University found that using LPG as a marine fuel can reduce annual fuel consumption by 7.5-10.4%, fuel cost by 8.8-25.9%, and carbon dioxide emissions by 10-14%. The study also highlights the potential for promoting LPG as an eco-friendly alternative to traditional fuels.
Researchers have shed light on the role of RUVBL1 and RUVBL2 proteins in the assembly and maturation of the spliceosome, a complex involved in cell splicing and alternative splicing. The study provides insights into the mechanisms responsible for the maturation of the splicing machinery.
Researchers have developed a new statistical toolkit using the fragility index to determine if clinical trial results are strong and reliable. The new method has been shown to be more flexible than previous versions, allowing researchers to test assumptions and consider implications of a wider range of outcomes.
Alternative data can improve market performance by encouraging firms to bring in more skilled people to extract unique insights. As funds acquire these skills, they can process more alternative data at a lower cost, leading to stronger performance for both the fund and the market.
A doctoral student at Texas A&M University has discovered blood outgrowth endothelial cells (BOECs) as an alternative to induced pluripotent stem cells (IPSCs) for organs-on-chips, offering a cheaper and more accessible option for patient-specific research. The new cells can be isolated from just 50-100 milliliters of blood and have sh...
Researchers investigated how providing information about alternative feedstuffs impacts consumer preferences. They found that consumers are more likely to prefer insect-based feed due to sustainability claims. The study emphasizes the importance of labelling and transparency for the acceptance of these alternatives.
Researchers have identified thousands of novel brain-expressed gene isoforms, revealing a complex web of protein production in the brain. The study suggests that genes expressed in the brain may produce far more proteins than previously thought, with potential implications for diseases such as Alzheimer's and schizophrenia.
A new study suggests that UK plant-based alternative food consumption has nearly doubled over the past decade, with younger generations and women being more likely to adopt this diet. The research found that plant-based milks were the most popular among the UK population, followed by vegan sausages and vegetable burgers.
A new computer program called Codetta can analyze the genome sequences of over 250,000 bacteria and archaea to identify alternative genetic codes. This could help scientists understand how genetic codes evolve and change.
Scientists from the University of Nottingham have discovered a new approach for structurally modifying bioactive molecules using visible light, providing a possible sustainable alternative to traditional methods. This method has the potential for extensive application in the design and production of new drugs.
A team led by David Kaplan at Tufts University aims to produce an alternative food source using cell-grown meat, driving efforts to enhance food sustainability and nutrition. The five-year project will combine interdisciplinary teams to evaluate consumer acceptance, environmental impact, and economic viability.
Researchers at MD Anderson Cancer Center reported that serial stereotactic body radiation therapy (SBRT) is a safe and effective treatment for oligometastatic renal cell carcinoma. The study showed promising results, with a median progression-free survival of 22.7 months and minimal toxicity.
A multidisciplinary team at Wayne State University has been awarded a grant to develop alternative sources of rare earth elements critical to advanced military and consumer technologies. The project aims to create a sustainable US rare earth element supply chain and mitigate potential supply disruptions.
Researchers have been exploring tribocatalysis as an alternative clean energy technology. The process converts mechanical energy into electrical energy through the triboelectric effect, with potential applications in material synthesis and energy conversion. Further research is needed to fully develop this promising field.
Researchers discovered that nickel can catalyze the cross-coupling of aryl ethers through a nickelate anion. This reaction pathway relies on the formation and stability of the catalyst, providing an alternative to traditional palladium-catalyzed cross-couplings.
A team of researchers at the University of Warwick has demonstrated a novel glycan-recognition technology for detecting SARS-COV-2 using sugars. The prototype devices showed promise in identifying COVID-19 positive swabs across various viral loads, including variants of concern.
A small study found that a wireless kit, comprising headphones and an app, may be a cheap alternative to traditional treatment of 'glue ear' in kids. The kit enables remote monitoring of hearing at home, reducing clinic visits and potentially avoiding surgery in many cases.
A new study suggests that extending the life of current cars can reduce CO2 emissions significantly more than replacing them with new, green vehicles. By keeping and using cars longer, the decrease in manufacturing emissions offsets additional emissions produced by existing cars.
A study conducted by RCSI has demonstrated that a saliva PCR test is almost as accurate as the standard nose and throat swab, enabling greater capacity for frequent testing. The saliva screening represents a less invasive alternative with the potential to increase compliance with screening.
A new precision medicine test has been developed using blood proteins to identify patients with idiopathic multicentric Castleman disease (iMCD) most likely to respond to siltuximab. The study also reveals Janus kinase (JAK) inhibitors as a promising alternative treatment option for those who do not respond to siltuximab.
A recent study by Chinese Academy of Sciences researchers found that circular RNA circURI1 inhibits the spread of gastric cancer cells. It achieves this by sequestering hnRNPM, modulating alternative splicing in gastric cancer cells. This breakthrough provides a new perspective on the molecular basis of cancer metastasis.
Researchers identified a novel mechanism by which circURI1 suppresses gastric cancer metastasis through hnRNPM decoy and alternative splicing modulation. This study provides new insights into the molecular basis of cancer metastasis and suggests circURI1 as a potential therapeutic target for diagnosis and treatment.
Researchers at MLU and Brazilian University of Pará create climate-friendly cement alternative by replacing limestone with Belterra clay, a previously unused overburden from bauxite mining. The new cement is just as stable as traditional Portland cement and reduces CO2 emissions during production.
Flipon genetics proposes that evolution happens on a faster time scale than Darwin imagined, with rapid adaptations occurring in real-time within individuals. This is achieved through the simple sequence repeats of DNA, which can adopt alternative shapes and transmit adaptations to offspring.
Researchers developed a sustainable source of corneal endothelial cells from pluripotent stem cells, reversing corneal transparency loss and promoting regrowth in rabbits and monkeys. The study suggests that stem cell-derived CECs may be a viable treatment option for patients with corneal endothelial dysfunction.
A Baylor University study assesses the relationship between large-scale renewable energy and biodiversity conservation. The research suggests that while some renewable energy sources, like hydropower, have been well-studied, others, such as solar, have unknown impacts on local ecosystems.
A study found that over half of university students in the Midwest have tried plant-based meat alternatives, with key motivators including trying new foods and environmental concern. Students who were more environmentally conscious and had a positive attitude towards plant-based options were more likely to try them.
Researchers at WashU Medicine discovered a single mutation in SARS-CoV-2 that allows the virus to enter human lung cells through an alternative route, which may evade COVID-19 antibodies or vaccines. The study suggests the virus can change and adapt in unexpected ways to cause infection.
A study found that plant-based protein shakes made from potato and rice proteins can effectively manage appetite and blood glucose levels, making them suitable for individuals with diabetes or obesity. The research showed that these plant-based shakes may be a sustainable alternative to milk-based whey protein shakes.
The NTU and GFI APAC partnership aims to equip students with expertise on alternative proteins and cultivated meat. The course will develop local talent for the alternative meats sector in Singapore and aligns with the country's '30 by 30' goal.
A new study by researchers at UC and Michigan State University found that electronic monitoring tethers failed to reduce reoffending among girls involved in the juvenile justice system. The study suggests that tethering may be harmful because it limits girls' access to treatment programs, leading to higher recidivism rates.
Key findings suggest PHA's rapid biodegradability is overstated in real-world conditions, but it remains a better alternative to non-biodegradable plastics. Several companies are planning to switch their packaging to PHA-based materials soon.
Researchers will examine regulation and disease relevance of alternative splicing in different types of heart cells. The project aims to map the path from splicing factor discovery to drug development.
Researchers have identified the alternative complement pathway as a key driver of IgA nephropathy, a chronic kidney disease. Iptacopan, an oral inhibitor of Factor B, has been shown to significantly reduce proteinuria and stabilize renal function in patients with IgAN, offering a new therapeutic approach.
A UCI-led study has identified key molecular mechanisms underlying complex traits and diseases, providing new insights into the role of genetic variation and environmental factors. The research reveals that specific molecular features associated with phenotypic variations contribute substantially to disease risk.
The Terasaki Institute has been awarded a grant by the Good Food Institute to develop an innovative method for producing cultivated meat. The project aims to address scalability and cost challenges in alternative protein production, using unique microcarriers to differentiate cell cultures.
The Skoltech team created a genome-wide atlas of developmental alternative splicing changes in seven organs across six mammal species and chicken. Alternative splicing plays a crucial role in forming organs like the brain, heart, and testes, but is less significant for others like the liver and kidneys.
A new study challenges claims of declining global sperm count, citing a 'biovariability framework' that suggests natural variation is the norm. The research aims to contribute to discussions on reproductive health and challenge racist assumptions in sperm count studies.
A new case report details the treatment of a patient with VITT (vaccine-induced thrombotic thrombocytopenia) using bivalirudin, an alternative to heparin. Early outcomes suggest that this approach may be safe and effective in treating these rare but serious clot reactions.
New research by Richard York found that adding alternative meat sources like poultry and fish increases overall meat consumption, rather than suppressing traditional grazing animal sources.
A novel radiant cooling system combines special panels with natural ventilation to minimize disease transmission and save energy in cities worldwide. By increasing outdoor air flow rates, this alternative solution ensures building occupants remain comfortable and rooms are adequately refreshed.
The ASN and NKF publish an interim report assessing alternative methods to diagnosing kidney diseases, highlighting the need for a standardized approach. The task force recommends replacing existing equations with a new method that is accurate, representative, and unbiased.
Scientists have developed a novel naturally derived cyan blue colorant from red cabbage anthocyanin pigments, which shows high stability over time. The new compound, Peak 2, can produce both blue and green colors in food products, offering an alternative to synthetic blue dye.
Researchers found that alternative seafood networks (ASNs) experienced unprecedented growth during the COVID-19 pandemic, as consumers temporarily relocalize their seafood purchases. This growth underscores the importance of functional diversity in supply chains and regional food systems for resilience, with policy changes and data col...
Researchers found that ibuprofen inhibits the alternative splicing event generating RAC1B, overexpressed in BRAF-mutated colorectal tumors. Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein kinase complex, promoting nuclear exclusion of SRPK1 and SRSF1.