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MIT neuroscientists build case for new theory of memory formation

Researchers suggest existing models of memory formation should be revised due to existence of 'silent engrams' which store memories even when they cannot be retrieved through natural cues. Memories are stored in a specific pattern of connections that form between cells during the first few minutes after an event occurs.

SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateOct 23, 2017

How we recall the past

Researchers have identified a distinct 'detour' circuit in the hippocampus that is necessary for memory recall, but not for memory formation. This circuit branches off from the original memory circuit and connects to the entorhinal cortex, enabling easier editing or updating of memories.

No direct flights for memory retrieval

Research finds that a neural stopover in the subiculum is necessary for retrieving episodic memories, but not forming them. Activating or inhibiting this pathway affects memory recall and stress hormone levels related to fear responses.

SourceRIKEN·JournalCell·DateAug 17, 2017

Superconducting nanowire memory cell, miniaturized technology

Researchers at the University of Illinois have developed a new nanoscale memory cell that holds promise for successful integration with superconducting processors. The device provides stable memory at a smaller size than other proposed memory devices, eliminating magnetic-field cross-talk and enabling faster and more powerful computing.

Understanding T cell activation could lead to new vaccines

Researchers have identified a key to generating effective tissue-resident memory T cells that can fight off infections in organs. By adjusting the strength of T cell receptor stimulation, scientists can promote the generation of these cells, which could lead to more efficient protection against viruses like Zika and HIV.

SourcePenn State·JournalPLOS Pathogens·DateMay 30, 2017

Estrogen alters memory circuit function in women with gene variant

Research reveals that fluctuations in estrogen can trigger atypical functioning in a key brain memory circuit in women with a common version of the gene, NIMH scientists have discovered. This finding may help explain individual differences in menstrual cycle and reproductive-related mental disorders linked to fluctuations in the hormone.

SourceNIH/National Institute of Mental Health·JournalMolecular Psychiatry·DateApr 25, 2017

Improving memory with magnets

Scientists at McGill University used magnetoencephalography and electroencephalography to study the relationship between theta waves and auditory memory. They found that applying transcranial magnetic stimulation (TMS) at the same frequency as natural theta waves improved memory performance, while arrhythmic TMS had no effect.

SourceMcGill University·JournalNeuron·DateMar 27, 2017

Super-sized memory is trainable and long lasting

After 40 days of daily training using a strategic memory improvement technique, individuals with typical memory skills more than doubled their memory capacity. Brain scans showed altered brain functions and similar connectivity patterns as those of world champion memory athletes. Four months later, recall performance remained high.

SourceCell Press·JournalNeuron·DateMar 8, 2017

Sound waves boost older adult' memory, deep sleep

A new study from Northwestern University finds that sound wave stimulation synchronized to brain waves triples memory scores in older adults and enhances deep sleep. The technique, which uses real-time brain wave analysis, shows promise as a non-meditation approach to improving brain health.

SourceNorthwestern University·JournalFrontiers in Human Neuroscience·DateMar 8, 2017

New system for forming memories

A study published in Science found that the entorhinal cortex replays memories of movement independently of the hippocampus, challenging the long-held view of the hippocampus as the primary memory region. The medial entorhinal cortex acts like a navigational system, providing cues for location and movement to the hippocampus.

Random access memory on a low energy diet

Researchers from Dresden and Basel have developed a novel memory chip concept that can store data magnetically without continuous refreshing, reducing energy consumption and heat generation. The breakthrough uses an electrical voltage instead of current to activate the magnetic material, enabling more efficient data storage.

SourceHelmholtz-Zentrum Dresden-Rossendorf·JournalNature Communications·DateJan 3, 2017

Deep brain stimulation may not boost memory

A recent study published in Neuron found that deep brain stimulation did not improve memory performance, with a range of impairment from 5% to 20%. However, the researchers suggest that a different stimulation protocol may be necessary to boost memory.

SourceCell Press·JournalNeuron·DateDec 7, 2016

How sleep deprivation harms memory

Researchers discover that five hours of sleep deprivation leads to a loss of connectivity between neurons in the hippocampus, a region associated with learning and memory. However, blocking the protein cofilin and allowing recovery sleep restores neuronal connections and improves memory processes.

SourceeLife·DateAug 23, 2016

New clues about the aging brain's memory functions

A European study led by Umea University Professor Lars Nyberg found a positive link between the dopamine D2 receptor and long-term episodic memory, which often declines with age. The research suggests that impairment of the dopamine system may play a crucial role in understanding age-related cognitive decline.

SourceUmea University·JournalProceedings of the National Academy of Sciences·DateJun 29, 2016

Need to remember something? Exercise 4 hours later!

A new study suggests that physical exercise after learning improves memory consolidation, particularly when done in a specific time window. The researchers found that exercising four hours after learning retained the information better two days later than those who exercised immediately or not at all.

SourceCell Press·JournalCurrent Biology·DateJun 16, 2016