Researchers from UMass Amherst have created a tiny sensor that can simultaneously measure electrical and mechanical cellular responses in cardiac tissue. This breakthrough device has the potential to lead-edge applications in cardiac-disease experiments and improve health monitoring for cardiac disease studies.
SourceUniversity of Massachusetts Amherst·JournalScience Advances·TypeExperimental study·DateAug 24, 2022
SUTD researchers leverage nanosecond electroporation to deliver cancer-related molecules into living cells with excellent viability. The platform enables pores to remain open for up to 720 minutes, paving the way for efficient drug delivery and other applications.
SourceSingapore University of Technology and Design·JournalNanoscale·DateAug 18, 2022
Researchers developed a small molecule that effectively controls tumor growth by inhibiting PD-1/PD-L1 binding, overcoming accessibility and cost issues of existing antibody treatments. The new molecule has advantages in terms of affordability and oral administration, making immunotherapy more accessible to all cancer patients.
SourceTel-Aviv University·JournalJournal for ImmunoTherapy of Cancer·DateAug 8, 2022
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
Researchers developed size-tunable PEG-grafted copolymers to target muscle tissues by exploiting the blood-muscle barrier. The optimal size range for extravasation was found to be between 11-32 nm, with accumulation in skeletal muscles of Duchenne muscular dystrophy model mice being significantly higher than in normal mice.
SourceInnovation Center of NanoMedicine·JournalJournal of Controlled Release·TypeExperimental study·DateMay 31, 2022
Researchers found that targeting both tumor and lymph node microenvironments with nanomedicine improves treatment response for metastatic triple negative breast cancer. Long-term tumor remission was achieved in mice models using nanoparticles to deliver immune-modulating drugs.
SourceMichigan Medicine - University of Michigan·JournalScience Translational Medicine·TypeExperimental study·DateMay 12, 2022
Researchers developed nanoparticles with a changeable net charge that facilitates intratumor accumulation and penetration, achieving 32.1% of injected dose/g of tissue. This study suggests using the changeable net charge as a promising strategy for tumor-targeted delivery based on the EPR effect.
SourceInnovation Center of NanoMedicine·JournalJournal of Controlled Release·TypeExperimental study·DateMay 8, 2022
A multidisciplinary team at CSIC introduces silicon chips into living cells, allowing study of cell division processes and potential for interfering with the cell cycle. This research opens new lines of investigation in nanomedicine.
SourceSpanish National Research Council (CSIC)·JournalAdvanced Materials·TypeExperimental study·DateApr 27, 2022
Researchers at Aarhus University have developed improved DNA nanostructures that can assemble biomolecules with multiple functions, increasing the effectiveness of cancer treatment. The new structures are more stable, non-toxic, and immune system-friendly than previous versions.
SourceAarhus University·JournalAngewandte Chemie International Edition·TypeExperimental study·DateApr 20, 2022
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Recent progress in targeted nanomedicine for managing resistance and toxicity of cisplatin in cancer therapy is reviewed. The article highlights strategies to increase cisplatin sensitivity through improved intracellular concentration and combination therapy, as well as novel approaches targeting tumor microenvironment and immunotherapy.
SourceInnovation Center of NanoMedicine·JournalJournal of Controlled Release·TypeLiterature review·DateApr 9, 2022
Recent nanomedicines are being explored for brain cancer treatment due to their ability to improve bioavailability and evade the blood-brain barrier. These supramolecular nanomedicines show potential in promoting superior therapeutic effects by targeting brain tumors specifically.
SourceInnovation Center of NanoMedicine·JournalAdvanced Drug Delivery Reviews·TypeLiterature review·DateApr 7, 2022
Researchers at MUSC have developed a device to remove toxic chemotherapy drugs, such as doxorubicin, from the blood after cancer treatment. The device uses heat and an activated carbon filter to effectively remove the drug, potentially reducing harmful side effects.
SourceMedical University of South Carolina·JournalCancers·TypeExperimental study·DateApr 6, 2022
Scientists have created a new technology using colour pigments from the food industry to stimulate nerve cells with the help of implantable mini solar cells. This innovation could lead to accelerated healing and prevention of complications in severe brain injuries, as well as potential applications in pain therapy and retinal implants.
SourceGraz University of Technology·JournalAdvanced Materials Technologies·TypeComputational simulation/modeling·DateApr 6, 2022
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
Researchers have developed a novel nanocarrier system that synergizes poly(l-ornithine) for mRNA protection with charge-conversion polymer for endosomal escape. This innovation enhances protein expression efficiency by approximately 80-fold, outperforming traditional PLL-based systems.
SourceInnovation Center of NanoMedicine·JournalMacromolecular Rapid Communications·TypeExperimental study·DateApr 5, 2022
Researchers at Tel Aviv University developed a drug delivery system based on lipid nanoparticles that utilize RNA to boost personalized cancer care. The nanodrug enhances chemotherapy effectiveness and reinvigorates the immune system, increasing sensitivity to cancer cells.
SourceTel-Aviv University·JournalScience Advances·DateApr 4, 2022
The team used a microscale diffuser to distribute ultrasound waves uniformly, reducing the risk of over-exposure or under-exposure. The device successfully stimulated cells in human embryonic kidney cells and neuron cells, as well as mice, with improved targeting.
SourceUniversity of California - San Diego·JournalAdvanced NanoBiomed Research·TypeExperimental study·DateMar 23, 2022
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
A new fabric developed by MIT engineers can detect subtle heartbeat features and the direction of sudden sounds, enabling real-time monitoring of vital signs. The fabric works like a microphone, converting sound vibrations into electrical signals.
SourceMassachusetts Institute of Technology·JournalNature·DateMar 16, 2022
Researchers at Massachusetts General Hospital found that using nanomedicines at lower, more frequent doses can normalize the tumor microenvironment and improve cancer treatments. The study showed that this approach can help correct abnormalities that protect tumors and improve blood vessel function and immune activation within a tumor.
SourceMassachusetts General Hospital·JournalJournal of Controlled Release·TypeExperimental study·DateMar 11, 2022
Researchers examine ways to target specific neurons using nanomedicine, aiming to improve treatment options for neurodegenerative diseases like Alzheimer's and Parkinson's. The study highlights the challenges of delivering drugs to specific populations of neurons in the brain.
SourceInnovation Center of NanoMedicine·JournalNanomedicine·TypeLiterature review·DateMar 9, 2022
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
Researchers at the University of South Australia have developed a new way to deliver chemotherapy drugs, using liposomal formulations that target tumors more effectively. This breakthrough could improve treatment outcomes for thousands of cancer patients, reducing side effects and improving quality of life.
SourceUniversity of South Australia·JournalPharmaceutics·TypeExperimental study·DateMar 9, 2022
Researchers have identified the impact of protein corona formation on nanoparticles' physiochemical and biological properties. This knowledge can be used to optimize carriers for nanomedical applications, improving the efficiency and effectiveness of biopharmaceutical delivery.
SourceAmerican Institute of Physics·JournalBiophysics Reviews·DateFeb 1, 2022
Researchers at Penn Medicine have discovered a new method to prevent the body's proteins from attacking treatment-carrying nanoparticles, allowing for more effective delivery of therapies. By coating nanoparticles with natural suppressors of complement activation, such as Factor I, the team has shown improved protection against immune ...
SourceUniversity of Pennsylvania School of Medicine·JournalAdvanced Materials·TypeExperimental study·DateJan 11, 2022
A new targeted nanomedicine treatment developed at the University of Chicago has shown promise in reducing vascular lesions caused by atherosclerosis. The treatment delivers medicine directly to inflamed cells, targeting the site of inflammation and inhibiting stenosis, the remodeling of vascular tissue that causes it to close off.
SourceUniversity of Chicago·JournalProceedings of the National Academy of Sciences·DateDec 6, 2021
Researchers have developed a ferritin-based nanomedicine that targets diverse leukemia types, improving therapeutic efficacy and reducing toxicity. The nanomedicine delivers arsenic to leukemia cells, enhancing killing effects while minimizing harm to normal tissues.
SourceChinese Academy of Sciences Headquarters·JournalNature Nanotechnology·DateOct 25, 2021
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Researchers created polymersomes that target highly invasive cancer cells, delivering anticancer drugs and preventing metastasis. The nanomachines showed strong antitumor effects in breast cancer models, inhibiting lung metastasis and prolonging survival.
SourceInnovation Center of NanoMedicine·JournalAdvanced Materials·DateOct 12, 2021
A new antibody delivery technology enhances anti-PD-L1 antibody accumulation in glioblastoma by 33-fold, achieving a 60% complete response rate with long-term immune memory. The technology also suppresses immune-related adverse events.
SourceInnovation Center of NanoMedicine·JournalNature Biomedical Engineering·DateOct 11, 2021
Researchers developed an AI tool that can quickly and accurately identify suspicious proteins in the body by analyzing their movements. The method, known as diffusional fingerprinting, uses machine learning algorithms to predict protein behavior with over 90% accuracy.
SourceUniversity of Copenhagen - Faculty of Science·JournalProceedings of the National Academy of Sciences·DateAug 31, 2021
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Researchers have discovered that dendrimer tentacles can avoid detection by the complement system, part of our immune system. This could lead to developing a new system for delivering drugs into the body without triggering an immune response.
SourceNewcastle University·JournalNature Communications·TypeExperimental study·DateAug 11, 2021
A new microneedle patch containing cerium nanoparticles has been designed to combat both primary causes of baldness: oxidative stress and insufficient circulation. The patch showed faster hair regrowth in a mouse model compared to a leading treatment.
SourceAmerican Chemical Society·JournalACS Nano·DateAug 11, 2021
Researchers have developed poly-ion complex (PIC) nanomicelles loaded with CPT1A inhibitors to deliver drugs into brain cells, reducing fatty acid oxidation and improving treatment for glioblastoma. The delivery system successfully increased cellular concentration of the cargo and biological activity.
SourceInnovation Center of NanoMedicine·JournalBiomaterials Science·TypeExperimental study·DateAug 3, 2021
Researchers explore integrating reactive oxygen species generation and prodrug activation to enhance cancer therapy. Stimuli-responsive nanomedicines can target tumors, generating ROS that activate drug release, offering promising synergetic therapy strategies.
SourceCompuscript Ltd·JournalBIO Integration·DateJul 6, 2021
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Researchers explore connections between preclinical and clinical modeling to develop unique animal-based disease models. Integration of active-targeting ligands and smart materials enhances nanomedicine functionalities, paving the way for new-concept nanoparticle-based drugs.
SourceCompuscript Ltd·JournalBIO Integration·DateJun 28, 2021
Research by MSU's Morteza Mahmoudi suggests that Covid-19 vaccines developed with nanomedicine may have different efficacies for men and women due to sex-based differences. The study highlights the importance of considering sex in vaccine development and research, particularly in using nanomedicines.
SourceMichigan State University·JournalNature Communications·DateMay 20, 2021
Researchers developed polymeric nano-micelles that target specific levels of c-Myc expression, a key factor in cancer cell proliferation. The study showed varying efficacy depending on tumor c-Myc expression levels, with higher expression associated with better antitumor activity.
SourceInnovation Center of NanoMedicine·JournalACS Nano·DateFeb 25, 2021
Researchers have developed a unique combination of microscopy techniques to study the biological effects of nanoparticles and their interaction with human plasma. This approach allows for an unprecedented view of the nanoparticle's 'corona', also known as its biological 'crown', which contains clues about how nanoparticles interact wit...
SourceMichigan State University·JournalNature Communications·DateJan 25, 2021
Researchers have developed ultra-small nanomedicines that stably deliver oligonucleotides to refractory cancers, such as brain tumors and pancreatic cancer. These nanomedicines use Y-shaped block copolymers and nucleic acid drugs, achieving high permeability in cancer tissues and stability in the bloodstream.
SourceInnovation Center of NanoMedicine·JournalJournal of Controlled Release·DateJan 19, 2021
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
The authors review future directions of nanomedicine development focusing on the mechanism of nanoparticle entry into tumors. Designing better nanoparticles to achieve efficient clinical transformation can be informed by a deep understanding of the mechanism of nanoparticle entry or the mode of action.
SourceCompuscript Ltd·JournalBIO Integration·DateDec 23, 2020
The Kawasaki Institute of Industrial Promotion has opened a new website for Project COINS, which aims to establish an in-body hospital network by 2045. The initiative is part of the Center of Innovation Program (COI) and will focus on creating innovative healthcare and medical technologies.
Researchers at Eindhoven University of Technology prove the Velcro method enhances selectivity in drug particle binding based on receptor number and strength. This allows precise targeting of diseased cells while distinguishing them from healthy ones.
SourceEindhoven University of Technology·JournalProceedings of the National Academy of Sciences·DateAug 24, 2020
Sky & Telescope Pocket Sky Atlas, 2nd Edition
Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.
The BIO Integration Virtual Conference Series July 2020 examines the intersection of nanomedicine, biology, and technology. Key topics include the integration of naturally occurring bioactive compounds into nanomedicine and nanoparticles meditated LncRNA silencing for effective cancer radiotherapy.
Scientists propose advanced engineering strategies for gas-releasing nanomedicines to enhance bioavailability and safety of therapeutic gases. These nanomedicines aim to maximize profits in gas therapy by providing controlled release and targeting cancer cells.
SourceScience China Press·JournalNational Science Review·DateMay 6, 2020
A nanomedicine expert proposes a cancer care model for managing COVID-19, focusing on early detection, regular monitoring, and targeted treatment. This approach could improve patient outcomes by providing systematic management of the pandemic.
SourceUniversity of Manchester·JournalNature Nanotechnology·DateApr 27, 2020
Researchers at Stockholm University discovered engineered silica particles can reduce food efficiency, leading to lower weight gain and improved metabolic profiles in mice. The study suggests these particles could be used to treat obesity and diabetes in humans.
SourceStockholm University·JournalNanomedicine·DateJan 14, 2020
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Researchers developed an exosome-based nanomedicine that increases tumor accumulation and penetration after intravenous administration. The biocompatible nanomedicines combine natural biomaterials with synthetic nanoparticles, demonstrating potential for improved anticancer drug efficacy.
SourceUniversity of Helsinki·JournalNature Communications·DateSep 17, 2019
Researchers have developed a nanotherapeutic called S-HDL that reduces inflammation in blood vessels, halting plaque accumulation and vessel wall inflammation in animal models. The new production method boosts therapeutic yields by up to 80-fold, paving the way for human application.
SourceAmerican Association for the Advancement of Science (AAAS)·JournalScience Translational Medicine·DateAug 21, 2019
Lauren Sciences LLC has received an AU$1 million grant from FightMND to advance its development of LAUR-301, a novel V-Smart Nanomedicine for ALS. The therapy aims to protect motor neurons and induce neuro-restoration, slowing or reversing the disease.
Researchers from NUS discovered that certain nanoparticles can widen the gap between blood vessel cells, making it easier for cancer cells to spread. This phenomenon, named NanoEL, accelerates tumor growth and causes circulating cancer cells to escape from blood circulation.
SourceNational University of Singapore·JournalNature Nanotechnology·DateJan 31, 2019
Recent review highlights latest advances in precise nanomedicine for intelligent cancer therapy, exploring metallofullerenol nanoparticles, supramolecular chemo-therapy, and DNA nanorobots. These strategies aim to improve cancer imaging and therapeutic applications while understanding nanotoxicity.
SourceScience China Press·JournalScience China Chemistry·DateJan 16, 2019
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
The ALS Association granted Lauren Sciences LLC its third award for developing LAUR-301, a V-Smart Nanomedicine for ALS. LAUR-301 aims to deliver GDNF across the blood-brain barrier and induce neuro-restoration in all ALS patients.
Research by Prof. Dr. Prasad Shastri at the University of Freiburg found that cancer cell membrane stiffness affects nanoparticle internalization; increasing stiffness enhances polymer nanoparticle entry through pathways rich in cholesterol.
Researchers created a nanomedicine platform that uses near-infrared imaging to detect tumors and kill residual cancer cells using phototherapy. The platform has shown great precision and thoroughness in cancer treatment, with promising results in mouse models.
SourceOregon State University·JournalTheranostics·DateDec 20, 2017
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
A $3 million collaboration between the University of Liverpool and Johns Hopkins University aims to develop novel, long-acting HIV medicines. The project seeks to create implantable technologies that can deliver drugs for weeks or months, potentially improving patient adherence.
Lauren Sciences LLC has received the second grant from Voices Against Brain Cancer to continue developing LAUR-401, its innovative V-Smart Nanomedicine for Glioblastoma Multiforme. The award confirms the successful development of LAUR-401 and anticipates its potential as a transformative therapeutic for brain cancer patients.
Lauren Sciences will use the grant to customize LAUR-301 with neurotrophic factor and deliver it to disease sites in central nervous system ALS mice. The company aims for LAUR-301 to enter human clinical trials and become a transformative V-Smart TM Nanomedicine for treating ALS.
The special focus issue brings together experts from various fields to discuss the past, present, and future of nanomedicine. It addresses current debates and future perspectives on nanomedical research, including social, ethical, and safety aspects.
SourceFuture Science Group·JournalNanomedicine·DateNov 20, 2015
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
The European Nanomedicine Characterization Laboratory (EU-NCL) aims to bring safe and efficient nanotherapeutics faster to patients. EU-NCL partners with international reference facilities to harmonize analytical protocols, providing a trans-disciplinary testing infrastructure for preclinical characterization.
SourceSwiss Federal Laboratories for Materials Science and Technology (EMPA)·DateJul 2, 2015
V-Smart Nanomedicine for glioblastoma multiforme (GBM) will target and deliver a known chemotherapeutic across the blood brain barrier, providing an effective new treatment option. The grant supports the development of this transformative therapeutic for brain cancer patients.
A special focus issue in Nanomedicine examines the intersection of nanomedicine and regenerative medicine, showcasing advancements in nanotopography, nanofunctionalization, and stem cell research. The field of nanoregeneration has grown exponentially over the last 15 years, with potential applications in drug discovery and cell targeting.
SourceFuture Science Group·JournalNanomedicine·DateMar 31, 2015
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
Researchers developed targeted biodegradable nano-drones that deliver an anti-inflammatory drug to fat deposits in arteries, successfully restructuring atherosclerotic plaques to make them more stable. The treatment reduced reactive oxygen species, increased collagen, and decreased plaque necrotic core.
SourceBrigham and Women's Hospital·JournalScience Translational Medicine·DateFeb 18, 2015
The FDA has approved dozens of nanodrugs without a formal definition, leading to case-by-case examination and nonbinding guidance. This complexity hinders the development of generic nanodrugs, potentially delaying price savings for patients.
SourceAmerican Chemical Society·JournalChemical & Engineering News·DateNov 12, 2014
Researchers found that a particle size of 50 nm is optimal for anti-cancer nanomedicines, with enhanced performance in vivo and improved tumor inhibition.
SourceUniversity of Illinois Grainger College of Engineering·JournalProceedings of the National Academy of Sciences·DateOct 15, 2014