The new guideline offers evidence-based recommendations for diagnosing and treating community-acquired pneumonia in adults, with a focus on outpatient settings. It suggests using amoxicillin as first-line empiric therapy, while also recommending more microscopic studies of respiratory tract samples to avoid unnecessary antibiotic use.
SourceAmerican Thoracic Society·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateOct 1, 2019
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SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Researchers discovered a novel weapon in bacteria arsenal that mimics common antibiotics, potentially filling gap left by antibiotic resistance. The 'toxic arrowhead' VgrG2b targets cell envelope and prevents division, causing cells to bulge and explode.
SourceImperial College London·JournalCell Reports·DateOct 1, 2019
Researchers at Imperial College London developed microneedle biosensors that accurately detect changing antibiotic concentrations in patients' bodies. The technology enables real-time monitoring with similar results to blood tests.
SourceImperial College London·JournalThe Lancet Digital Health·DateSep 30, 2019
Researchers at RUDN University have created non-toxic derivatives of chitosan with enhanced antibacterial activity, comparable to modern antibiotics. These novel materials can be used as preservatives in food coatings, providing a safer and more sustainable solution.
SourceRUDN University·JournalFood Chemistry·DateSep 30, 2019
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Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
The Global Antibiotic Research and Development Partnership (GARDP) and Entasis Therapeutics have partnered to develop a new oral antibiotic, zoliflodacin, for treating uncomplicated gonorrhea. The phase 3 trial will assess the treatment's efficacy in preventing persistent infections.
SourceGlobal Antibiotic Research & Development Partnership·DateSep 30, 2019
Researchers at Newcastle University have confirmed that bacteria can lose their cell wall to avoid detection by antibiotics, leading to recurring urinary tract infections. The study found that L-form switching allows bacteria to survive and re-form their cell wall, making it harder for the immune system to target them.
SourceNewcastle University·JournalNature Communications·DateSep 26, 2019
Researchers at MIPT have identified a promising class of antibiotics, 2-pyrazol-1-yl-thiazole derivatives, which exhibit antibacterial properties and inhibit protein synthesis. The discovery was made possible by a semi-automatic analysis method that enabled the screening of over 125,000 molecules.
SourceMoscow Institute of Physics and Technology·JournalThe Journal of Antibiotics·DateSep 26, 2019
A new compound derived from eushearilide has shown significant antibacterial properties against various disease-causing bacteria, including MRSA. This finding offers relief for immunocompromised people who are susceptible to life-threatening fungal and bacterial infections.
SourceTokyo University of Science·JournalMolecules·DateSep 25, 2019
Only half of patients with sinus, throat, ear infections received recommended first-line antibiotics, a rate below industry standard. Retail clinics and emergency departments had higher rates, while urgent care centers lagged.
SourceAmerican Society for Microbiology·JournalAntimicrobial Agents and Chemotherapy·DateSep 25, 2019
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Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
Researchers at University of Warwick have made a breakthrough in understanding the functions and structures of key enzymes in assembling an antibiotic with activity against Acinetobacter baumannii, a highly resistant pathogen. Understanding these enzymes could enable more effective versions of the antibiotic to be created.
SourceUniversity of Warwick·JournalNature Chemistry·DateSep 24, 2019
Scientists at the University of Surrey discovered that green tea's EGCG can restore antibiotic activity against antibiotic-resistant bacteria Pseudomonas aeruginosa. The study found that combining EGCG with aztreonam significantly reduced bacterial numbers and improved survival rates in infected larvae.
SourceUniversity of Surrey·JournalJournal of Medical Microbiology·DateSep 23, 2019
Researchers identified six genes responsible for producing plant antibiotics that control fungal disease resistance in maize. This breakthrough could lead to improved disease resistance in rice and other crops using the same genetic pathways.
SourceUniversity of California - San Diego·JournalNature Plants·DateSep 19, 2019
Researchers mapped global trends in antimicrobial resistance rates among food animals in low- and middle-income countries between 2000 and 2018. The study found that antibiotic-resistant bacteria are on the rise, with high rates of resistance identified in antibiotics commonly used in food production.
SourceCenter for Disease Dynamics, Economics & Policy·JournalScience·DateSep 19, 2019
A new study has found that initiating antibiotics immediately before obtaining blood cultures significantly affects their sensitivity and ability to diagnose bacterial and fungal infections. This change in guidelines may reduce mortality rates from sepsis, a life-threatening condition with a 20% mortality rate.
SourceUniversity of Arizona Health Sciences·JournalAnnals of Internal Medicine·DateSep 17, 2019
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Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Scientists engineer a plasmid that removes antibiotic resistance genes from Enterococcus faecalis, reducing its abundance by threefold in mouse models. The technology uses CRISPR-Cas9 and aims to combat antimicrobial resistance in hospitals.
SourceAmerican Society for Microbiology·JournalAntimicrobial Agents and Chemotherapy·DateSep 16, 2019
Researchers found that 2.5% of women and 12.1% of men without established CVD could derive net benefit from aspirin treatment for 5 years. The study used data from a well-characterized web-based decision support program in New Zealand, identifying persons likely to benefit from aspirin treatment based on personalized benefit-harm analy...
SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·DateSep 16, 2019
Scientists have identified thousands of novel messenger proteins in human microbiomes, which could lead to new medicines. A new TB drug has been approved, offering hope for treatment-resistant forms of the disease.
SourceDOE/Lawrence Berkeley National Laboratory·JournalCell·DateSep 12, 2019
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GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
A study by the University of Cologne found that expert feedback significantly reduces the length of antibiotic therapies and improves treatment decisions among pediatricians. The experiment showed that providing feedback can be a useful means to address excessive antibiotic use.
SourceUniversity of Cologne·JournalMedical Decision Making·DateSep 12, 2019
Researchers at Brown University discovered that diet can mitigate or exacerbate changes in the gut microbiome caused by antibiotics. In a mouse study, diet high in fiber and low in simple sugars protected certain beneficial bacteria from antibiotic harm.
SourceBrown University·JournalCell Metabolism·DateSep 12, 2019
A new antibiotic-coated shunt has been shown to significantly reduce infection rates in patients with hydrocephalus. The BASICS trial found that the innovative treatment saved the NHS approximately £130K per infection averted, resulting in estimated annual savings of £7 million.
SourceUniversity of Liverpool·JournalThe Lancet·DateSep 12, 2019
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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers found that fluoroquinolone antibiotics, such as Ciprofloxacin, are associated with an increased risk of heart problems, including aortic and mitral regurgitation. Current users face a 2.4 times greater risk compared to patients taking amoxicillin.
SourceUniversity of British Columbia·JournalJournal of the American College of Cardiology·DateSep 10, 2019
A study found that premature babies' gut microbiomes remain disrupted after antibiotic treatment, leading to an increased risk of disease and health problems later in life. The research suggests that minimizing antibiotic use in preemies may help prevent these issues.
SourceWashU Medicine·JournalNature Microbiology·DateSep 9, 2019
Treating preterm infants with antibiotics for more than 20 months can lead to less diverse bacterial populations in their gut, containing more antibiotic resistance genes. The study suggests that early-life antibiotic use may promote allergies and other health issues later in life by reducing the diversity of microbial communities.
SourceNIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development·JournalNature Microbiology·DateSep 9, 2019
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Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Researchers create new way to detect resistant bacteria, enabling clinicians to reserve stronger antibiotics for most patients. The modified antibiotic can be attached to a sensor surface to detect resistance enzymes, paving the way for rapid diagnostic tests.
SourceUniversity of York·JournalACS Applied Materials & Interfaces·DateSep 9, 2019
Researchers found a new mechanism for resistance gene transmission in intestinal bacteria that's independent of antibiotics. Persistent bacteria can survive and share genes with other bacteria, spreading resistance, according to ETH Zurich scientists.
Researchers discovered powerful genes in duckweed that protect against a wide range of harmful microbes and pests, paving the way for use in bioreactors, drug production, and biofuel development. The study's DNA sequencing approach could lead to numerous societal benefits and further unlock the potential of duckweed.
SourceRutgers University·JournalProceedings of the National Academy of Sciences·DateSep 5, 2019
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DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
A new study modelled the effects of antibiotic prescriptions on developing antibiotic-resistant bacteria in the River Thames. Reducing antibiotic use by 80% is necessary to avoid a surge in superbugs, which could pose a more immediate risk to humanity than climate change.
SourceUK Centre for Ecology & Hydrology·JournalPLOS ONE·DateSep 4, 2019
Bacteria behind hospital infections have been found to close tiny doors in their cell walls, blocking antibiotics. This mechanism allows researchers to design new drugs that can 'pick the locks' and allow antibiotics into bacterial cells.
SourceImperial College London·JournalNature Communications·DateSep 2, 2019
Fuzhong Zhang receives nearly $2 million NIH grant to investigate metabolic diversity and its relation to antibiotic persistence in bacteria. He aims to understand what causes cells with different metabolic activity and develop strategies to control these differences.
New antibiotics are prescribed in only about a quarter of CRE infections due to high costs, despite being classified as the best choice by pharmacists. The slow adoption is attributed to concerns about accelerating antibiotic resistance and limited data on their effectiveness.
SourceUniversity of Pittsburgh·JournalOpen Forum Infectious Diseases·DateAug 26, 2019
Researchers study how gonorrhea develops resistance to antibiotics, identifying key mutations and structural changes. Understanding these mechanisms can lead to the development of new treatments and diagnostic tests.
SourceMedical University of South Carolina·JournalJournal of Biological Chemistry·DateAug 23, 2019
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Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
A large-scale survey in rural Thailand and Laos found that people's attitudes towards antibiotics were often consistent with public health recommendations, but linked to disproportionately high rates of prescribed antibiotics. Wealthier and more educated individuals were also associated with receiving antibiotics from informal sources.
Researchers at Johns Hopkins Kimmel Cancer Center found that taking a single course of antibiotics may boost the risk of developing colon cancer a decade later. The study, published in the journal Gut, highlights the need for judicious use of antibiotics and careful stewardship.
Research published in Gut journal suggests a link between antibiotic use and increased risk of bowel cancer, particularly for cancers of the proximal colon. Conversely, rectal cancer risk was found to be lower among those prescribed antibiotics, possibly due to differences in gut microbiome activity.
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Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Two antimicrobial stewardship interventions were found to be feasible in community hospitals, increasing antibiotic appropriateness and reducing unnecessary use. The interventions, which included pharmacist approval after the first dose and engagement with prescribers, showed promise in improving stewardship practices.
SourceJAMA Network·JournalJAMA Network Open·DateAug 16, 2019
Researchers analyzed data from 27,000 Canadian nursing home residents with advanced dementia and found significant differences in end-of-life care between men and women. Men were less likely to receive invasive procedures, physical restraints, and antibiotic therapy in the last 30 days of life compared to women.
SourceJAMA Network·JournalJAMA Network Open·DateAug 16, 2019
Researchers at UNC School of Medicine find that adding rhamnolipids enhances the potency of aminoglycoside antibiotics against Staph infections, including MRSA. The study suggests a new strategy to overcome antibiotic resistance and has implications for treating various bacterial species.
SourceUniversity of North Carolina Health Care·JournalCell Chemical Biology·DateAug 14, 2019
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
Researchers followed a long-term UTI sufferer and found that recurring infections came from a single bacterial reservoir in the body. This discovery could lead to more effective treatments by targeting the intestinal reservoir rather than just treating the bladder.
SourceUniversity of Queensland·JournalNature Communications·DateAug 13, 2019
Researchers extracted genetic programs for glycopeptide antibiotic production from Actinobacteria, revealing precursors date back over 1 billion years. The study shows that resistance co-evolved with production as a means of self-protection for producing bacteria.
SourceMcMaster University·JournalNature Microbiology·DateAug 12, 2019
Researchers at Rice University and UTHealth have discovered that vancomycin-resistant Enterococci (VRE) can develop resistance to daptomycin in more than one way. The study's findings provide new insights into the mechanisms of antibiotic resistance, which could lead to the development of new treatment strategies or 'co-drugs' targetin...
SourceRice University·JournalAntimicrobial Agents and Chemotherapy·DateAug 12, 2019
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
A new study found that nearly half of patients with UTIs were not tested for the infection, leading to unnecessary antibiotic prescriptions and increased risk of antibiotic resistance. The researchers argue that doctors need access to rapid diagnostics tests to accurately diagnose and treat UTIs.
SourceUniversity of Leeds·JournalEClinicalMedicine·DateAug 12, 2019
Researchers at Monash University have discovered an antibiotic that can prevent the life-threatening diarrhea caused by C. difficile. The treatment strategy could also counter diseases caused by other similar bacteria, including anthrax. Studies show that cephamycins can reduce spore production of C. difficile and Bacillus cereus.
SourceMonash University·JournalNature Microbiology·DateAug 12, 2019
A Finnish study has found that bowel preparation before colon surgery does not reduce surgical site infections or complications. The study of 400 patients showed no benefits to the procedure, suggesting it may be unnecessary.
SourceUniversity of Helsinki·JournalThe Lancet·DateAug 9, 2019
A team of scientists has discovered previously unknown binding sites on a bacterial enzyme that could guide novel approaches to antibiotic design. The researchers identified key sections of the MraY enzyme that can be targeted with new drugs to inhibit the spread of certain bacterial infections.
SourceHokkaido University·JournalNature Communications·DateJul 31, 2019
Researchers discovered antibiotic properties of a natural product that selectively inhibits pathogen growth while leaving beneficial microbes intact. Synthetic derivatives of this substance have shown enormous antibiotic efficiency against Moraxella catarrhalis and malaria parasites.
SourceUniversity of Konstanz·JournalChemical Science·DateJul 30, 2019
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Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Researchers found that cigarette smoke can change the DNA and characteristics of pathogenic microbes like MRSA, making them more resistant to antibiotics. This stress response sparks an emergency mutation, resulting in hardy variants that are better equipped to resist drugs.
SourceUniversity of Bath·JournalScientific Reports·DateJul 30, 2019
Antibiotic-resistant genes were found in London's freshwater sources, with the River Thames having the highest levels. The genes come from human and animal waste, which contaminates water bodies through wastewater discharge. Researchers are now experimenting with slow sand filtration to remove these genes.
SourceUniversity College London·JournalJournal of Microbiological Methods·DateJul 25, 2019
Researchers discovered that giving antibiotics to mice and humans before a liver transplant led to improved liver function after surgery. The treatment inhibited bacteria causing inflammation, reducing organ rejection and accelerating cell removal, resulting in better outcomes for patients.
SourceUniversity of California - Los Angeles Health Sciences·JournalJournal of Clinical Investigation·DateJul 22, 2019
Nonprescription antibiotic use is a significant public health concern, with varying prevalence rates across different socioeconomic groups. The study highlights the need for increased awareness and education to prevent unnecessary antibiotic use and its associated adverse events.
SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·DateJul 22, 2019
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Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
A recent study found that kissing is a significant route of transmission for gonorrhoea, with rates of infection higher among men who kiss their partners compared to those who do not. The researchers argue that increased awareness and control measures are needed to address the rising global incidence of gonorrhoea.
Active surveillance for carbapenem-resistant Enterobacteriaceae (CRE) is now performed in half of centers, a significant increase from the previous study. Financial support for physician stewardship medical directors has also increased to 78% since 2013.
SourceSociety for Healthcare Epidemiology of America·JournalInfection Control and Hospital Epidemiology·DateJul 17, 2019
A new study found that using a CRP finger-prick blood test reduced antibiotic use by 20% in people with COPD flare-ups without affecting recovery or well-being. This approach may help tackle antibiotic resistance.
SourceCardiff University·JournalNew England Journal of Medicine·DateJul 11, 2019
Researchers found that the rate at which a patient's immune system clears slow-growing variants of methicillin-resistant Staphylococcus aureus (MRSA) is crucial in determining whether antibiotics can cure the infection. A new mathematical model suggests that a drug targeting slow-growing MRSA variants may be the most effective treatmen...
SourcePLOS·JournalPLOS Computational Biology·DateJul 11, 2019
A multicenter study found that antibiotic stewardship interventions can significantly reduce overuse of antibiotics for viral acute respiratory infections. By implementing a bundle of evidence-based strategies, institutions can cut antibiotic overuse by one-third, even among high-performing systems.
SourceSociety for Academic Emergency Medicine·JournalAcademic Emergency Medicine·DateJul 10, 2019
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Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
Researchers at Inserm and Université de Rennes 1 have created new antibiotics effective against Gram-positive and negative multi-resistant bacteria. The compounds, known as peptidomimetics, also appear to prevent the development of resistance when used in mice models.
SourceINSERM (Institut national de la santé et de la recherche médicale)·JournalPLOS Biology·DateJul 9, 2019
Researchers successfully combined ceftazidime-avibactam and fosfomycin to fight P. aeruginosa in mouse models, outperforming individual antibiotics. The combination reduced the presence of the bacterium significantly, offering a potential therapeutic strategy against superbugs.
SourceCase Western Reserve University·JournalThe Journal of Infectious Diseases·DateJul 8, 2019
A new study found that nearly two-thirds of pneumonia patients in Michigan hospitals received excessive antibiotic prescriptions, with most written during the discharge process. This over-treatment can lead to physical side effects and does not improve patient outcomes.
SourceMichigan Medicine - University of Michigan·JournalAnnals of Internal Medicine·DateJul 8, 2019
A new evidence review suggests that few nutritional supplements or dietary interventions offer any protection against cardiovascular disease or death. Some may even cause harm, according to a meta-analysis published in Annals of Internal Medicine.
SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·DateJul 8, 2019
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
The study identifies nine master regulators controlling key pathogenic pathways in Pseudomonas aeruginosa, offering potential targets for new antibiotics. An online platform and R package have also been developed to facilitate the analysis of the regulatory network.
SourceCity University of Hong Kong·JournalNature Communications·DateJul 3, 2019
A recent study by the University of Birmingham has identified a key pathway involved in protecting bacteria against antibiotics. The researchers discovered that phospholipids are transported towards the outer membrane through a series of proteins, which could lead to the development of new antibiotic treatments.
SourceUniversity of Birmingham·JournalNature Microbiology·DateJul 3, 2019