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Fibroblasts: Hidden drivers of heart failure progression

Researchers discovered that cardiac fibroblasts use a signaling pathway to promote harmful changes in the heart, weakening its ability to pump blood efficiently. Blocking this pathway in mice models improved heart function, suggesting that fibroblasts could be a potential target for new therapeutic strategies.

SourceOkayama University·JournalNature Cardiovascular Research·TypeExperimental study·DateOct 29, 2025

NUH and NUS launch new Molecular Imaging and Theranostics Centre to strengthen patient care and research

The new Molecular Imaging and Theranostics Centre at NUH and NUS Medicine enables faster, safer and more precise diagnoses, while researchers can observe real-time tracer movement throughout the body. This opens possibilities for validating next-generation diagnostics and therapies, advancing theranostics.

First 3D genetic mapping of the heart uncovers genes implicated in sudden death

A new study has uncovered 42 genetic locations associated with hypertrophy of the left ventricle, a major risk factor for sudden death. The research, conducted using three-dimensional MRI images and genome-wide analysis, could lead to earlier identification of individuals at greater risk.

SourceMedical Research Council (MRC) Laboratory of Medical Sciences·JournalCirculation Genomic and Precision Medicine·TypeComputational simulation/modeling·DateOct 7, 2025

New international guideline provides expert guidance for PET imaging of patients with coronary artery disease

A new clinical guideline has been issued for 18F-flurpiridaz PET myocardial perfusion imaging, providing recommendations for patient selection, imaging protocols, and interpretation of results. The guideline aims to enhance diagnostic accuracy and optimize resource utilization for the evaluation of coronary artery disease.

SourceSociety of Nuclear Medicine and Molecular Imaging·JournalJournal of Nuclear Medicine·DateSep 18, 2025

Closing the care gap: IOF position paper identifies barriers and solutions to global undertreatment of osteoporosis

The International Osteoporosis Foundation identifies critical global barriers to osteoporosis care, including limited DXA scanning and outdated treatment criteria. The IOF advocates for a paradigm shift in bone health management worldwide, recognizing high fracture risk as a valid criterion for treatment and reimbursement.

SourceInternational Osteoporosis Foundation·JournalOsteoporosis International·TypeLiterature review·DateSep 9, 2025

A patient’s own cartilage cells may be the key to help healing after hip surgery

A recent study by researchers at the University of Missouri has made a groundbreaking discovery using patient's own cartilage cells to aid in healing after hip surgery. The research team successfully cultured and expanded cartilage cells, or chondrocytes, in the lab, paving the way for future clinical applications.

SourceUniversity of Missouri-Columbia·JournalArchives of Orthopaedic and Trauma Surgery·TypeExperimental study·DateAug 19, 2025

Noninvasive stent imaging powered by light and sound

Researchers have developed a noninvasive method for visualizing stents through skin using photoacoustic microscopy, potentially reducing the need for surgical access and X-ray exposure. The technique uses sound waves generated by light absorption to create high-resolution images of stents in various conditions.

SourceOptica·JournalOptics Letters·DateJul 25, 2025

Beyond the mammogram: Study finds differences between benign and cancerous breast calcifications

Researchers at the University of Illinois found that benign and cancerous breast calcifications have unique structures and formation processes. The study provides a new classification scheme and opens the possibility of treating benign calcifications using certain drugs.

SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalScientific Reports·TypeObservational study·DateJul 23, 2025

Temozolomide and radiation treatment lead to dramatic tumor shrinkage and improvement of hearing in an adult brainstem glioma patient with a rare IDH2 mutation

Researchers successfully treated a patient with a rare IDH2-mutant brainstem astrocytoma using temozolomide and radiation, resulting in significant tumor shrinkage and improved hearing. The patient's unique genetic profile was identified through magnetic resonance spectroscopy and surgical biopsy, allowing for targeted treatment.

SourceNiigata University·JournalFrontiers in Oncology·DateJul 16, 2025

Scientists pioneer 3D temperature mapping inside living tissue using light and AI

Researchers have developed a groundbreaking technique that maps temperature in three dimensions within biological tissue using invisible light and artificial intelligence. This new technology has the potential to improve early disease detection and treatment monitoring without the need for costly or invasive imaging technologies.

SourceUniversità Ca' Foscari Venezia·JournalNature Communications·DateJul 16, 2025

New MRI approach maps brain metabolism, revealing disease signatures

Researchers at the University of Illinois Urbana-Champaign have developed a new non-invasive MRI approach that visualizes brain metabolism and detects metabolic alterations associated with brain diseases. The technique uses magnetic resonance spectroscopic imaging to provide insights into brain function and disease processes.

SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalNature Biomedical Engineering·TypeExperimental study·DateJul 1, 2025

‘Closed loop’ learning barriers prevent doctors from using life-saving bedside ultrasound

A new study reveals six 'closed loop' barriers that prevent doctors from using point-of-care ultrasound, leading to missed opportunities for life-saving interventions. The researchers propose practical steps to address these cultural and practical challenges, aiming to increase POCUS uptake and benefit patients.

SourceUniversity of Cambridge·JournalAdvances in Health Sciences Education·DateJun 23, 2025

Researchers solve ultrasound imaging problem using seismology technique

A team of scientists from Colorado State University and the University of São Paulo have developed a seismological solution to improve the resolution of ultrasound images for lung monitoring. This breakthrough could lead to improved critical care for patients, including continuous lung monitoring at the bedside. The technique uses seis...

SourceColorado State University·JournalIEEE Transactions on Biomedical Engineering·DateJun 11, 2025

Drought-resilient plant holds promise for future food production, study finds

Researchers at Colorado State University have demonstrated the reversal of embolism in a type of wild grass, which can recover from extended drought within 24 hours. This finding has significant implications for improving agricultural productivity and food security, as it could potentially be bred into crops to make them more resilient...

SourceColorado State University·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateJun 5, 2025

New technology developed at the Lewis Katz School of Medicine at Temple University promises faster, earlier diagnosis of deadly form of heart failure

A novel screening approach called VEST uses virtual echocardiography to identify patients at high risk of pulmonary arterial hypertension, a life-threatening form of heart failure. The tool has been shown to generate accurate PAH risk scores without manual calculations and can guide timely referrals for expert care.

SourceTemple University Health System·JournalAmerican Heart Journal·DateJun 4, 2025

With CCTA poised to transform PCI planning, SCAI/SCCT publish expert opinion document

The SCAI/SCCT expert opinion document presents a comprehensive framework for using CCTA to guide PCI. It outlines current evidence and future opportunities, providing practical guidance on image acquisition, interpretation, and procedural strategy. The document aims to bridge the gap between imaging and intervention, emphasizing educat...

SourceSociety for Cardiovascular Angiography and Interventions·JournalJournal of the Society for Cardiovascular Angiography & Interventions·TypeCommentary/editorial·DateMay 1, 2025

Building trust in artificial intelligence for healthcare: Lessons from clinical oncology

A new review advocates for building confidence in AI applications by implementing robust data governance frameworks, enhancing transparency, and involving stakeholders. The authors emphasize the importance of addressing ethical implications and ensuring equitable access to AI-driven innovations in clinical oncology.

SourceMary Ann Liebert, Inc./Genetic Engineering News·JournalAI in Precision Oncology·TypeCommentary/editorial·DateApr 30, 2025

Retinal disorder diagnosis improved by new AI-powered medical imaging, study shows

Researchers have introduced DSFN to improve the speed and accuracy of diagnoses of retinal disorders. This AI-powered medical imaging technique combines retina images with vascular distribution information to accurately locate the fovea in complex clinical scenarios, enabling doctors to detect early signs of ocular diseases.

SourceXi'an Jiaotong-Liverpool University·JournalIEEE Journal of Biomedical and Health Informatics·TypeComputational simulation/modeling·DateSep 12, 2024

CNIC scientists discover a new cardiovascular risk factor and identify a drug able to reduce its effects

Researchers at CNIC discover clonal hematopoiesis as a new cause of atherosclerosis, while identifying the ancient medication colchicine as a potential treatment. Clonal hematopoiesis is linked to an increased risk of cardiovascular disease, with no influence on the progression of mutated blood cells.

SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalNature Medicine·TypeRandomized controlled/clinical trial·DateAug 30, 2024

UVA research cracks the autism code, making the neurodivergent brain visible

A multi-university research team led by University of Virginia engineering professor Gustavo K. Rohde has developed a system that can accurately spot genetic markers of autism in brain images. The system uses generative computer modeling technique called transport-based morphometry, which reveals brain structure patterns that predict v...

Gastroenterologists generally trust and accept use of AI medical tools in clinics and hospitals, finds NTU Singapore study

A study by Nanyang Technological University found that eight in 10 gastroenterologists in the Asia-Pacific region accept and trust AI-powered tools for diagnosing colorectal polyps. The study also highlights the need for more research into what influences doctors' acceptance of AI in their medical practice.

AI model may yield better outcomes for prostate cancer

A new AI model has been shown to significantly improve the accuracy of diagnosing prostate cancer by 45 times compared to doctors' measurements alone. The system assists in mapping out the boundaries of cancerous tissue, reducing the risk of underestimation and enabling more precise treatment planning and effective surgical procedures.

Would the highly sensitive transparent ultrasound transducer revolutionize biomedical imaging technology?

A novel transparent ultrasonic transducer (TUT) developed by POSTECH researchers offers exceptional optical transparency and maintains acoustic performance, surpassing conventional limitations. This breakthrough enables high-depth-to-resolution ratios for ultrasound imaging, with applications in various medical devices and fields.

SourcePohang University of Science & Technology (POSTECH)·JournalNature Communications·DateMar 10, 2024