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Dual-energy CT iodine concentration differentiates lung cancer from pulmonary metastases

Ringlike peripheral high iodine concentration maps from dual-energy CT can help guide management in patients with known lung cancer and an indeterminate solitary nodule. This finding showed excellent interobserver agreement, high specificity, and independently predicted pulmonary metastasis.

SourceAmerican Roentgen Ray Society·JournalAmerican Journal of Roentgenology·TypeObservational study·DateJan 11, 2023

Kidney disease measures are associated with structural brain damage across different domains of etiology

Reduced kidney function and increased urine albumin excretion are associated with brain volume reduction in regions typically affected by Alzheimer's disease and other dementia etiologies. Cognitive decline is common in patients with kidney disease, and this study provides new insights into the etiology and localization of brain damage.

SourceNational Kidney Foundation·JournalAmerican Journal of Kidney Diseases·DateSep 27, 2022

UMass Amherst researcher uses graphene for same-time, same-position biomolecule isolation and sensing

New research by UMass Amherst professor Jinglei Ping demonstrates the use of graphene for electrokinetic biosample processing and analysis, allowing for faster and more efficient detection of biomolecules. This breakthrough enables the creation of smaller lab-on-a-chip devices with improved time and size efficiencies.

SourceUniversity of Massachusetts Amherst·JournalACS Nano·TypeExperimental study·DateJul 18, 2022

Virtual CT scans cut patient radiation exposure in half during PET/CT studies

Researchers developed an artificial intelligence method to generate high-quality 'PET/CT' images, reducing radiation exposure and allowing for more frequent imaging. This innovation has the potential to provide more accurate assessment of disease progression and treatment efficacy, ultimately improving patient care.

SourceSociety of Nuclear Medicine and Molecular Imaging·JournalJournal of Nuclear Medicine·DateJun 12, 2022

Penn Medicine study reveals imaging approach with potential to detect lung cancer earlier, at the cellular level

Researchers at Penn Medicine have developed an imaging agent that detects cancer cells in real-time during biopsies, offering promise for earlier and more accurate diagnoses. The technology, known as NIR-nCLE, uses a combination of near-infrared tracers and confocal laser endomicroscopy to identify microscopic cancer cells.

SourceUniversity of Pennsylvania School of Medicine·JournalNature Communications·TypeExperimental study·DateMay 18, 2022

Half of all women experience false positive mammograms after 10 years of annual screening

A study published in JAMA Network Open found that half of all women will experience at least one false positive mammogram over a decade of annual breast cancer screening with 3D mammography. The risk of false positives is lower for women screened every other year, and non-dense breasts also show a lower false positive risk.

SourceUniversity of California - Davis Health·JournalJAMA Network Open·TypeData/statistical analysis·DateMar 25, 2022

Eye imaging technology breaks through skin by crossing beams

Duke researchers developed a method to increase the depth of view of optical coherence tomography (OCT), allowing for clear images from beyond a millimeter beneath the skin's surface. The new technique, known as dual-axis OCT, tilts the light source and detector to collect more scattered light from deep tissues.

SourceDuke University·JournalBiomedical Optics Express·TypeExperimental study·DateDec 1, 2021

High-speed holography of cells spots physical beacons of disease

Researchers at Duke University developed a holographic system that can image and analyze tens of thousands of cells per minute to spot signs of disease. The technique distinguished between healthy samples and cancerous or pre-cancerous cells with nearly 100% accuracy, using just four basic cellular physical parameters.

SourceDuke University·JournalFrontiers in Physics·TypeExperimental study·DateNov 30, 2021

The Lancet: Half of the global population lack access to basic diagnostics for many common diseases, new estimates suggest

New estimates suggest nearly half (47%) of the global population has limited or no access to key tests and services for diagnosing common diseases. The Lancet Commission on Diagnostics calls for urgent investment and training to improve access to testing in primary care, especially point-of-care testing.

SourceThe Lancet·JournalThe Lancet·TypeSystematic review·DateOct 6, 2021

New 10-year patient safety analysis highlights areas for improvement in acute medical units

A new study analyzes 377 severe harm and death incidents in acute medical units across England and Wales between 2005-2015. The most common incident types were diagnostic errors, medication-related errors, and failures in monitoring patients. Implementing electronic prescribing systems and checklists can reduce diagnostic errors, while...

SourceSAGE·JournalJournal of the Royal Society of Medicine·TypeData/statistical analysis·DateAug 4, 2021

Are diagnostic imaging studies with positive conclusions or titles published faster?

A study found that diagnostic imaging studies with positive conclusions were associated with a shorter time from study completion to publication, contributing to an overrepresentation of positive results in the test accuracy literature. Studies with positive titles showed no significant association with faster publication times.

SourceAmerican Roentgen Ray Society·JournalAmerican Journal of Roentgenology·DateNov 13, 2020

Combination of imaging methods improves diagnostics

Researchers at Helmholtz Zentrum München developed an approach to quantify gadolinium-based contrast agents in tissue using MALDI-MS imaging, correlating it with MRI images. This combination improves diagnostic value by detecting tissue-related kinetics of contrast agents used in myocardial infarction models.

Few to no work efficiencies when different providers read different scans on same patient

A new study by the American College of Radiology found that any potential work efficiencies gained when different providers interpret different medical imaging scans on the same patient are minimal and vary by procedure. The study suggests that Medicare's estimates of potential work savings were greatly exaggerated, with a maximum redu...

SourceAmerican College of Radiology·JournalJournal of the American College of Radiology·DateApr 9, 2013

Canadian C-spine rule more accurate in diagnosing important cervical spine injuries than other rules

A study published in Canadian Medical Association Journal found that the Canadian C-spine rule is more accurate than NEXUS in diagnosing important cervical spine injuries. The rule's better diagnostic accuracy and lower rate of false negatives make it a preferable choice for assessing cervical spine imaging needs.

SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·DateOct 9, 2012

Medical School implements successful radiation protection program for undergraduate medical students

A medical school in Ireland has successfully implemented a radiation protection program for undergraduate medical students, improving their knowledge of radiation protection. The program was designed as an e-learning module and resulted in significant improvements in students' post-module radiation protection knowledge.

SourceAmerican College of Radiology·JournalJournal of the American College of Radiology·DateMar 1, 2012

New clinical guideline for low-back pain

The new guideline recommends clinicians rely on evidence-based therapies, limit X-rays, and consider non-pharmacologic options like exercise therapy, chiropractic care, and massage. The guidelines aim to reduce unnecessary radiation exposure and improve patient outcomes for low-back pain treatment.

SourceOregon Health & Science University·JournalAnnals of Internal Medicine·DateOct 2, 2007