Articles tagged with Preventive Medicine
Researchers developed antibody–drug conjugates that combine CD4 mimic and neutralizing antibodies to target HIV entry, showing seven times better efficacy than existing approaches. The strategy aims to block HIV before it enters the host cell, offering a more targeted therapeutic profile and potentially reducing adverse effects.
A new commentary raises concerns about editorial bias in scientific publishing, particularly in relation to COVID-19 vaccine safety and efficacy. The authors highlight the rejection of a case report and literature review that raised potential links between mRNA vaccines and rare blood cancers.
A new wearable textile sensor, TAESS, integrates electrocardiography and impedance plethysmography to measure core cardiovascular parameters continuously. It enables real-time tracking of blood pressure, stroke volume, cardiac output, heart rate, and systemic vascular resistance during daily activities.
A study in Lesotho shows that trained laypeople can achieve better blood pressure control in their community compared to normal treatment in healthcare facilities. The layperson-assisted model was found to be safe and effective, reducing hospital admissions and improving access to healthcare for underserved rural communities.
A one- and three-month antibiotic treatment regimens both had few adverse reactions and high rates of completion in preventing active tuberculosis, says a new study published in PLOS Medicine. The regimens were deemed successful and neither proved superior to the other.
Research highlights increased mortality risks among individuals with autism spectrum disorder, intellectual disability, or cerebral palsy compared to the general population. The study's findings can inform public health strategies to address health disparities and excess mortality associated with developmental disabilities.
A recent poll found that 42% of people over 50 haven't gotten either flu or COVID-19 vaccines in the past six months. The leading reason for not getting vaccinated was a lack of perceived need, despite clear evidence showing vaccination reduces the risk of serious illness and death in older adults.
A study published in JAMA found that salpingectomy significantly lowers the risk of developing tubo-ovarian carcinoma. The procedure, typically performed during unrelated pelvic or abdominal surgery, is now recommended as a preventive measure for eligible women.
A new study confirms that opportunistic salpingectomy (OS), which involves removing fallopian tubes during hysterectomy or tubal ligation, reduces the risk of serous ovarian cancer by nearly 80%. The procedure leaves ovaries intact, preserving hormone production and minimizing side effects.
Adverse experiences throughout life increase dementia and stroke risks, with depression as a mediating factor. Implementing life-course interventions addressing psychological trauma and mental health can reduce neurovascular disease burden.
The new platform developed by UVA Health scientists can produce vaccines much faster, cheaper, and more easily than traditional approaches. The platform's proof-of-concept demonstrates its ability to produce highly immunogenic vaccines that can be manufactured at extremely low cost.
According to a new study, Massachusetts is close to eliminating cervical cancer due to its low incidence rate of 4.3 cases per 100,000 in recent years. In contrast, the Southeast and Southwest regions have higher rates of 11.2 and 9.9 cases per 100,000, respectively, making it challenging for these states to reach elimination goals.
A UCLA-led team has discovered a novel mechanism of kidney stone formation involving bacteria, challenging the long-held assumption that stones develop solely through chemical and physical processes.
Researchers have found a nonlinear dose-response relationship between exercise and hepatic steatosis, indicating that a combination of aerobic and resistance exercises can produce clinically meaningful improvements. The study suggests that exercising above 130 MET-min/week can lead to significant reductions in hepatic steatosis.
Researchers have identified a new method to predict asthma exacerbations with a high degree of accuracy, analyzing data from three large asthma cohorts. The study found that the ratio between sphingolipids and steroids was the most powerful predictor of future health.
Researchers at the University of Virginia Health System have discovered how the keto diet protects against epilepsy seizures by regulating brain cell activity. The team found that a specific cellular receptor, HCAR2, plays a crucial role in reducing seizures, and may be targeted for new treatments.
Researchers have developed a blood test that can predict Crohn's disease years before symptoms appear. The test measures immune response to flagellin, a protein found on gut bacteria, which is elevated in individuals long before they develop the disease.
A study found that vaccinating pregnant women increases protection for infants against whooping cough, a highly contagious disease. The research team also showed that whole-cell pertussis vaccines provide longer-lasting protection than acellular vaccines, and recommends vaccination during pregnancy as a double-layered defense.
A study of 198 male rugby players found that injuries caused by indirect contact had a high incidence and burden, while tackle direction was associated with injury severity. The insights gained can guide targeted prevention programs for knee injuries in rugby.
The study found a significant increase in alcohol-related hospitalizations between 2016 and 2022, with rising mortality rates and extended lengths of stay. Preventive efforts are needed to reduce population-level alcohol consumption and improve treatment outcomes for individuals with alcohol use disorder.
A new study found that playing classic video games such as Super Mario Bros. and Yoshi can evoke childlike wonder, boosting overall happiness and reducing burnout risk in young adults. The research used mixed methods, including interviews and surveys, to understand how these games resonate with students.
A meta-analysis found nirsevimab to be associated with reduced hospitalizations and emergency department visits for lower respiratory tract infections in young children. This suggests the potential of nirsevimab to decrease respiratory-related morbidity in this population.
A new study found that quadrivalent human papillomavirus (HPV) vaccination is associated with a reduced risk of high-grade vulvovaginal lesions. Expanding HPV vaccination, especially at younger ages, may help prevent these lesions.
BGI Genomics convened its 2025 European Partnership & Networking Summit in Budapest, fostering innovation, collaboration, and growth. The event introduced its comprehensive NGS solution, Gensiro, integrating AI and automation to streamline laboratory workflows.
A new white paper by biostatistician Professor Jeffrey S. Morris analyzes the multicomponent US vaccine safety monitoring system, including VAERS and other components. The study suggests improvements to enhance the system's effectiveness and sustain a robust safety monitoring infrastructure.
A case-crossover study found that air conditioning in nursing homes reduces mortality among older adults during extreme heat. The study suggests that AC provision may be crucial for preventing mortality in congregate care settings.
A study found that only 6% of FDA-approved drugs reflect the US racial and ethnic makeup, with a decline in Black and Hispanic enrollment between 2021 and 2023. The researchers recommend setting diversity goals at preclinical stages and collecting biological samples to understand how people's bodies react to medications.
The Fuster Prevention Forum will teach clinicians effective ways to educate children, parents, and educators in their communities on nutrition, physical activity, and emotional well-being. The program aims to create a culture of prevention and promote sustainable, community-based initiatives.
A new study estimates that substance use disorders result in nearly $93 billion in lost productivity in the US, including $3,703 per adult. The analysis highlights the need for prevention and treatment strategies to reduce harm and costs beyond healthcare expenses.
The program provides financial aid and unique clinical experiences to medical students, encouraging them to become community physicians. UCF College of Medicine hopes the program can be used as a national model to address the nation's primary care physician shortage.
A survey study found that US voters generally support government role in ensuring safe vaccines, with high partisan divide among Trump and Harris supporters. Vaccine requirements for schools show similar support across parties.
Researchers at CU Anschutz have discovered a novel therapy combination to offer new hope to ovarian cancer patients who do not respond to existing treatments. The combination of a PARP inhibitor and SM08502 boosts the effectiveness of treatment, even for patients resistant to PARP inhibitors.
The UCF Health Mobile Health Clinic provides free high-quality healthcare services to underserved communities, serving as a real-world classroom for medical and nursing students. The clinic aims to reduce preventable conditions and improve long-term health through comprehensive screenings, chronic disease monitoring, and education.
A large clinical trial published in JAMA Surgery shows that prehabilitation can reduce disability after surgery in older adults with frailty, provided they fully participate in the program. Participants who completed at least 75% of exercises had significantly lower levels of disability after surgery.
A randomized clinical trial shows that semaglutide improves glycemic control and weight outcomes in individuals with schizophrenia. The study suggests using glucagon-like peptide-1 receptor agonists as an early intervention strategy to reduce cardiometabolic risk in this population.
A new study suggests that sweat can reveal information about a person's health, including hormone levels, medication doses, and early detection of diseases like diabetes and cancer. Wearable sensors using artificial intelligence can detect specific metabolites in sweat, providing personalized health insights.
A new study by ESMT Berlin finds that fractional-dose vaccines can significantly reduce infections during epidemics, especially in low-resource settings. The researchers identify vaccination policies that minimize infections while accounting for limited stockpiles and administration capacity.
A cross-sectional study found that US population faces significant challenges with nervous system disorders, impacting 180.3 million people, mainly due to stroke, Alzheimer's disease, diabetic neuropathy, and migraine conditions.
A new genetic study found that people without prior suicidal thoughts or behaviors have fewer psychiatric diagnoses and genetic risk factors for psychiatric conditions compared to those with known suicidality. This suggests that conventional wisdom on how to reduce suicide may need to be rethought.
Current USPSTF guidelines exclude two-thirds of patients from age-based screening, disproportionately affecting women and never-smokers. Age-based screening has been shown to improve detection and demonstrated superior cost-effectiveness compared to existing programs.
Lung cancer screening has the potential to prevent 3 times more deaths and gain 3 times more life-years than current levels. Increasing awareness and accessibility of lung cancer screening could lead to wider adoption.
A study by NTU Singapore researchers found that enlarged perivascular spaces, or 'clogged drains', in the brain are a likely early-warning sign of Alzheimer's disease. The condition can be visually identified on routine MRI scans, complementing existing methods to detect Alzheimer's earlier.
A new approach developed by University of Waterloo researchers uses social media posts to identify early warning signs of increasing vaccine skepticism. This method can detect patterns in data much more effectively than traditional methods, providing a bigger lead time before an outbreak occurs.
A study published in Journal of Translational Medicine found that successful root canal treatment can reduce inflammation linked to heart disease and improve levels of blood sugar and cholesterol. The researchers discovered a link between monitoring blood metabolic markers after dental treatment, which could help assess recovery and risk.
The Phase 3 study demonstrated the safety and non-inferiority of EuTYPH-C Inj.® Multi-dose compared to a World Health Organization (WHO) prequalified comparator TCV, Typbar TCV®. The vaccine was shown to be well-tolerated across all age groups with no serious adverse events.
Exercise promotes angiogenesis and lymphangiogenesis through molecular signaling pathways, enhancing vascular function and immune response. This process offers potential interventions to combat age-related decline and disease, including cardiovascular diseases, muscle atrophy, and metabolic disorders.
The Blue Zones Certification Course recognizes clinicians with the knowledge to promote longevity, well-being, and health equity. Clinicians will gain expertise in applying evidence-based lifestyle habits to prevent chronic diseases.
A cross-sectional study found significant associations between state-level firearm ownership and all-cause and firearm-specific homicide among pregnant women. The results suggest that prevention efforts should focus on women during pregnancy, particularly in states with higher firearm ownership rates.
Researchers at UVA School of Medicine found that the breakdown of protective brain structures called perineuronal nets leads to social memory loss in Alzheimer's patients. Preventing the degradation of these nets may lead to new treatments to prevent or delay the disease.
This study confirms the role of negative reinforcement in chronic opioid use, contributing to addiction development. The findings suggest that this mechanism is present even after regular opioid use, highlighting potential for more effective prevention and treatment strategies.
The Leopoldina discussion paper recommends realigning German development cooperation to focus on both prevention and medical treatment for childhood blindness. The approach, called 'Global Clinical Care', aims to strengthen local care capacities and provide training for ophthalmic specialists through institutional partnerships.
A study of almost 10 million patients in Ontario found that those living over 30 km from their family physician were more likely to visit the emergency department for nonurgent reasons and had fewer visits with a family physician. The distance also negatively impacted preventive screening for certain cancers.
A nationwide Swedish study found that many young people who died from cardiac arrest had recently sought medical care and showed signs of heart problems. The study suggests that fainting, seizures, and abnormal ECG findings in young people should be taken more seriously to identify those at risk before a sudden arrhythmic death occurs.
Provincial partnerships with corporate-provided virtual care programs raise concerns about access, quality of care, and data privacy. Governments must ensure healthcare standards are met, protect patient data, and maintain transparency around contracts and profits. The authors advise caution before introducing corporate entities in the...
Research links low body weight in young Japanese women to reduced gut microbial diversity, with an increased presence of inflammatory species. The study suggests that improving eating habits could lead to improvements in gut microbiota and body weight.
The Annenberg Public Policy Center survey finds that most American adults are unclear about the dangers of measles and the value of vaccination. The survey also shows a decline in support for MMR vaccination among parents, from 90% in November 2024 to 82% in August 2025.
A new study reveals how prenatal alcohol exposure impairs key brain cells and circuits, leading to cognitive inflexibility and increased risk of compulsive alcohol use. Researchers identified a specific brain cell affected by early alcohol exposure, providing a clear target for developing more effective treatments of FASD.
The research aims to develop an intervention for incarcerated people to address the challenge of engaging with MOUD treatment after release. Massachusetts has received federal approval for a Section 1115 waiver to provide Medicaid benefits to incarcerated individuals, expanding access to healthcare and support services.
The Framingham offspring study found that approximately 10% of participants experienced significant hearing loss over a 25-year period, with the prevalence increasing with age. The study suggests that early detection and intervention may help prevent or slow the progression of hearing loss.
A cohort study found that night light exposure was a significant risk factor for developing cardiovascular diseases among adults over 40. Avoiding light at night may be a useful strategy for reducing the risks of cardiovascular diseases.