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Columbia researchers find link between serotonin and heart valve disease

A new study led by Columbia researchers discovered a link between serotonin and heart valve disease, specifically degenerative mitral regurgitation. The study found that patients taking selective serotonin reuptake inhibitors (SSRIs) were more likely to develop severe mitral regurgitation and require surgery at a younger age.

SourceColumbia University Irving Medical Center·JournalScience Translational Medicine·TypeExperimental study·DateJan 27, 2023
Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Association of rurality with risk of heart failure

A study published in JAMA Cardiology found that rurality is associated with a higher risk of heart failure among predominantly low-income individuals in the southeastern United States. The inequity highlights the need for targeted primary prevention efforts for rural populations.

SourceJAMA Network·JournalJAMA Cardiology·DateJan 25, 2023

500,000 missed out on blood pressure lowering drugs during pandemic

Researchers found that nearly half a million people missed starting medication to lower their blood pressure during the Covid-19 pandemic, leading to thousands of avoidable cardiovascular events. Identifying individuals who missed out on treatment could reduce these events by just over 2,700.

SourceHealth Data Research UK·JournalNature Medicine·TypeObservational study·DateJan 19, 2023

A dietary supplement leads to remarkable regression in atherosclerotic lesions

Researchers from Osaka University found that tricaprin supplementation leads to remarkable regression of coronary artery plaque and resolution of symptoms in patients with triglyceride deposit cardiomyovasculopathy. The study's findings provide a novel treatment concept for coronary atherosclerosis.

SourceOsaka University·JournalEuropean Heart Journal·TypeCase study·DateJan 4, 2023
SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

New pediatric investigation article reviews the potential of transcatheter pulmonary valve replacement for congenital heart disorders

The procedure requires thorough pre-procedural evaluation and assessment of anatomical and hemodynamic data. Long-term results indicate that TPVR can effectively restore RVOT function, while improving survival rates and reducing the need for reintervention across age groups. Vigilant testing is recommended to avoid rare but serious com...

SourceCactus Communications·JournalPediatric Investigation·TypeCommentary/editorial·DateJan 3, 2023

Association of time to surgery after COVID-19 infection with risk of postoperative cardiovascular morbidity

A study of nearly 4,000 patients found that the longer the time between COVID-19 diagnosis and surgery, the greater the risk of major cardiovascular events during or following surgery. This association could inform discussions on optimal surgical timing and perioperative outcomes for patients with a history of COVID-19 infection.

SourceJAMA Network·JournalJAMA Network Open·DateDec 14, 2022

No advantage to Medicare Advantage seen in heart attack survival

A new study published in JAMA found that choosing a Medicare Advantage plan does not significantly improve heart attack survival rates compared to traditional Medicare. Despite this, Medicare Advantage participants still had higher rates of certain care procedures and lower hospital readmission rates.

SourceMichigan Medicine - University of Michigan·JournalJAMA·TypeData/statistical analysis·DateDec 7, 2022

Tropic cyclones on the rise in low- and middle- income countries yet remain least studied of climate-related events

Research highlights the need for high-quality studies on tropical cyclones in low- and middle-income countries to understand long-term consequences. The public health impact extends beyond injuries and cardiovascular diseases, affecting neuropsychiatric conditions and infectious diseases.

SourceColumbia University's Mailman School of Public Health·JournalEnvironmental Health Perspectives·DateNov 30, 2022
Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

Obesity drug helps teens lose weight, study finds

A new study published in the New England Journal of Medicine found that semaglutide, an approved obesity drug for adults, also helps adolescents with obesity lose weight and have healthier hearts. After 68 weeks, 72.5% of participants who received semaglutide had achieved at least 5% weight loss compared to just 17% on placebo.

SourceUniversity of Pittsburgh·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateNov 2, 2022

UCSF study sheds light on the reasons behind sex differences in myocarditis

A UCSF-led study sheds light on the mechanisms behind sex differences in ICI-induced myocarditis, a potentially fatal side effect of cancer immunotherapy. The research suggests that immune checkpoint inhibitors may interact with sex hormones to cause cardiac toxicity in female patients.

SourceUniversity of California - San Francisco·JournalScience Translational Medicine·DateNov 2, 2022

Best blood thinner for minimising bleeding risk identified

A large-scale comparison of direct oral anticoagulants has identified apixaban as the drug with the lowest risk of bleeding. The study, published in Annals of Internal Medicine, found that apixaban had a 19-28% lower risk of gastrointestinal bleeding compared to other DOACs.

SourceUniversity College London·JournalAnnals of Internal Medicine·TypeObservational study·DateOct 31, 2022

Favine protein found to potentially protect against vascular disease

Researchers at Osaka University have developed a mouse model that shows Favine protein can protect against atherosclerosis and thrombosis. The study also found that reduced levels of Favine are associated with calcification and thrombus formation, revealing a new potential therapeutic target for treating atherosclerosis.

SourceOsaka University·JournaliScience·TypeExperimental study·DateOct 17, 2022
CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

Cleveland Clinic researchers identify diabetes drug metformin as potential atrial fibrillation treatment in collaborative research

Researchers found that metformin targeted 30 genes associated with atrial fibrillation, showing direct effects on gene expression for eight. The study suggests metformin may be a promising candidate for treating atrial fibrillation due to its potential to reduce the risk of complications such as stroke and heart failure.

SourceCleveland Clinic·JournalCell Reports Medicine·DateOct 11, 2022

Care gap: Hospital readmission rate for younger women is higher than for younger men after a heart attack

A new study found that younger women hospitalized with heart attacks had a significantly higher prevalence of cardiac risk factors and comorbidities compared to younger men. This led to higher rehospitalization rates and all-cause readmission rates, emphasizing the need for ongoing efforts to improve prevention strategies.

SourceElsevier·JournalCanadian Journal of Cardiology·TypeData/statistical analysis·DateOct 5, 2022

Assessing functional outcomes in survivors of first-time stroke

A cohort study of 4,443 patients with first-time strokes found that early recovery curves and long-term decline patterns varied across functional domains. Clinical factors such as age, sex, and stroke type significantly impacted activities of daily living performance at 60 months.

SourceJAMA Network·JournalJAMA Network Open·DateSep 23, 2022
Apple AirPods Pro (2nd Generation, USB-C)

Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.

Heart medication shows potential as treatment for alcohol use disorder

A new study suggests that spironolactone, a medication for heart problems and high blood pressure, may also be effective in reducing alcohol drinking. The research found that increasing doses of spironolactone decreased alcohol consumption in mice and rats, as well as in humans with excessive alcohol drinking.

SourceNIH/National Institute on Drug Abuse·JournalMolecular Psychiatry·TypeExperimental study·DateSep 19, 2022

The blood pressure monitor of your dreams

Researchers are developing wearable tonometric sensors that can collect blood pressure data without disrupting patients' sleep. The new cuffless monitoring system uses gecko-inspired adhesion technology to provide accurate readings.

SourceUniversity of Pittsburgh·DateSep 15, 2022

Study suggests walnuts are bridge to better health as we age

Researchers found that eating walnuts early in life is associated with a lower risk of heart disease, obesity, and diabetes. The study suggests that walnuts may act as a 'bridge food' to promote healthy nutrition and lifestyle habits throughout life.

SourceKetchum New York·JournalNutrition Metabolism and Cardiovascular Diseases·TypeObservational study·DateSep 14, 2022

TAVR is an affordable and effective strategy for treating aortic stenosis patients

A budget impact analysis found that catheter-based TAVR is an affordable and effective strategy for treating aortic stenosis patients, with lower total costs compared to surgical SAVR. The study showed that the upfront cost of TAVR is partially offset by reduced healthcare resources, making it a more efficient option.

SourceElsevier·JournalCanadian Journal of Cardiology·TypeComputational simulation/modeling·DateSep 12, 2022

Dedicated women’s heart centers can improve accurate diagnoses and outcomes

A prospective study in the Canadian Journal of Cardiology found that dedicated women's heart centers can significantly improve clinical and psychological outcomes for women with myocardial ischemia. The study, which followed 154 patients, showed a significant decrease in chest pain frequency and improved quality of life after attending...

SourceElsevier·JournalCanadian Journal of Cardiology·TypeObservational study·DateSep 7, 2022
Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

Transplanted gut bacteria causes cardiovascular changes in mice

Researchers found that transplanted gut bacteria from mice with obstructive sleep apnea caused increased blood pressure and impaired coronary function in recipient mice. Probiotics improved symptoms for the recipients but not the donor mice, highlighting a potential therapeutic strategy to mitigate cardiovascular disease.

SourceUniversity of Missouri-Columbia·JournalEuropean Respiratory Journal·TypeExperimental study·DateSep 7, 2022

Fewer hospitalizations for home-based cardiac rehab patients

A Kaiser Permanente study found that patients in home-based cardiac rehabilitation had fewer hospitalizations than those in center-based rehab, with benefits seen across diverse patient populations. The home-based program improved accessibility and outcomes for high-risk patients.

SourceKaiser Permanente·JournalJAMA Network Open·DateAug 25, 2022

The prevalence of hypertension in low- and middle-income countries increases more sharply in rural areas

A meta-analysis of nearly 300 studies reveals a higher hypertension prevalence in urban areas but with a narrowing gap over time and socio-economic development, indicating rapid increase in rural areas. The study highlights the need for increased awareness and control measures in rural areas to address the growing burden of hypertension.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalPLOS Medicine·TypeMeta-analysis·DateAug 22, 2022
Fluke 87V Industrial Digital Multimeter

Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

Wrist-worn devices are shown by mass general researchers to be cost-effective for screening of atrial fibrillation

Researchers from Massachusetts General Hospital found that wrist-worn devices are more cost-effective than traditional electrocardiograms and pulse palpation for screening individuals with atrial fibrillation. The use of these devices was also associated with a reduction in stroke incidence.

SourceMassachusetts General Hospital·JournalJAMA Health Forum·TypeComputational simulation/modeling·DateAug 5, 2022

New heart model to help treat patients with heart failure

Researchers at RCSI University have created a new lab-based model to test devices for heart failure with preserved ejection fraction. The model enables testing of the left atrium and ventricle, two independently controlled chambers that simulate blood flow during the resting phase.

SourceRCSI·JournalFrontiers in Cardiovascular Medicine·DateJul 26, 2022
GoPro HERO13 Black

GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.

Major expansion of open-source neuroimaging data set to boost stroke recovery research

A newly expanded data set of brain scans from stroke patients called ATLAS now includes 1,271 MRI images with manually segmented lesions, facilitating large-scale stroke recovery research. Researchers hope to develop algorithms to automate lesion segmentation, enabling clinicians to predict patient responses to therapies.

SourceKeck School of Medicine of USC·JournalScientific Data·TypeImaging analysis·DateJun 27, 2022
Davis Instruments Vantage Pro2 Weather Station

Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

Chinese Medical Journal review explores the role of macrophages in the progression of acute kidney injury to chronic kidney disease

A recent review article highlights the crucial role of macrophages in the progression from acute kidney injury (AKI) to chronic kidney disease (CKD). The study suggests that targeting specific signaling pathways and altering macrophage activation can prevent renal fibrosis and CKD. Therapeutic strategies such as clodronate liposomes an...

SourceCactus Communications·JournalChinese Medical Journal·TypeLiterature review·DateJun 20, 2022

New screening test for those at risk of sudden cardiac arrest

Researchers have created a new electrical test to screen hundreds of gene mutations, pinpointing harmful mutations that cause inherited heart disorders and sudden death. The breakthrough can identify genetic variants associated with neurological conditions, muscle and kidney diseases.

SourceVictor Chang Cardiac Research Institute·JournalAmerican Journal of Human Genetics·TypeExperimental study·DateJun 9, 2022
Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

Timing of heart surgery crucial, research shows

A new study published in Open Heart found that patients with asymptomatic severe aortic stenosis benefit from early valve replacement surgery to prevent irreversible heart muscle damage. The research showed that timing of surgery is crucial in reducing mortality and hospitalization rates.

SourceUniversity of East Anglia·JournalOpen Heart·TypeMeta-analysis·DateMay 17, 2022

Cardiac progenitor cells generate healthy tissue after a heart attack

A team of researchers has successfully treated damaged pig hearts with cardiac progenitor cells, demonstrating the formation of new cardiac tissue and improved cardiac function. The treatment could potentially be used to treat patients with serious heart failure, particularly older patients with coexisting conditions.

SourceTechnical University of Munich (TUM)·JournalNature Cell Biology·TypeExperimental study·DateMay 12, 2022

From cavefish to humans: Evolution of metabolism in cavefish may provide insight into treatments for a host of diseases such as diabetes, heart disease, and stroke

Researchers studied cavefish genome-wide map of liver tissue to understand metabolism evolution and its potential applications for humans. The study found striking similarities in metabolic adaptations among cavefish populations, raising questions about universal adaptation mechanisms that could be triggered in other species like humans.

SourceStowers Institute for Medical Research·JournalNature Genetics·TypeExperimental study·DateMay 12, 2022
Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

Atherosclerotic plaques “talk” with the brain

Researchers discovered a connection between atherosclerotic plaques and the central nervous system, involving immune cells, nerves, and cardiovascular tissues. This 'ABC' circuit can be modulated or disconnected, potentially leading to innovative therapies for treating atherosclerosis.

SourceIstituto Neurologico Mediterraneo Neuromed I.R.C.C.S.·JournalNature·TypeExperimental study·DateApr 27, 2022

Doctors diagnosing fetal heart disease benefit from explanatory AI

Researchers found that AI-enhanced diagnosis helps doctors accurately detect fetal congenital heart disease, with fellows making the most accurate diagnoses. The new system uses graphical charts to represent the AI's analysis of ultrasound videos, improving accuracy and trust among medical professionals.

SourceRIKEN·JournalBiomedicines·DateApr 4, 2022

Cleveland Clinic-led trial finds that experimental ‘gene silencing’ therapy reduces lipoprotein(a), an important risk factor of heart disease, by up to 98%

A Cleveland Clinic-led trial found that an experimental 'gene silencing' therapy significantly reduced blood levels of lipoprotein(a), a key driver of heart disease risk, by up to 96%-98%. The therapy targets the gene responsible for Lp(a) production and has shown strong efficacy with no major safety concerns reported.

SourceCleveland Clinic·JournalJournal of the American Medical Association·DateApr 3, 2022

Smokers less likely to survive a heart attack

Researchers found smokers have significantly lower A1AT levels, which may reduce cardiac tissue protection during a heart attack. No difference was detected in hypertensive and non-hypertensive individuals.

SourceExperimental Biology·DateApr 2, 2022
Garmin GPSMAP 67i with inReach

Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.

Experimental Biology 2022 press materials available now

This year's Experimental Biology 2022 meeting features groundbreaking studies on COVID-19 vaccine-associated symptoms in non-menstruating people, a plant compound showing promise for alleviating food allergies, and the potential of omega-3s to boost immunotherapy's cancer-fighting power. Researchers also explore the safety of using CBD...

SourceExperimental Biology·DateMar 25, 2022

People with diabetes who eat less processed food at night may live longer

A study published by The Endocrine Society found that eating potatoes in the morning, whole grains in the afternoon, and less processed meat in the evening may improve long-term survival in people with diabetes. This eating pattern is associated with better heart health outcomes.

SourceThe Endocrine Society·JournalThe Journal of Clinical Endocrinology & Metabolism·DateMar 15, 2022
Sky & Telescope Pocket Sky Atlas, 2nd Edition

Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.

Urine trouble now! When your kidneys tell on your heart

Researchers found that impaired kidney function is preferentially associated with cardioembolic stroke in a large cohort of patients. Low filtration rates and high urine protein levels predicted increased risk of cardioembolic stroke, disability, and mortality.

SourceNational Cerebral and Cardiovascular Center·JournalNeurology·DateMar 14, 2022

New discovery could phase out medications from pig inteestines

Researchers at the University of Copenhagen have made a groundbreaking discovery that could phase out medications derived from pig intestines. The team has successfully created a synthetic alternative to heparin in a laboratory setting, using cell factories, similar to insulin production.

SourceUniversity of Copenhagen - The Faculty of Health and Medical Sciences·JournalScience Advances·TypeExperimental study·DateFeb 23, 2022

Daily activities like washing dishes reduced heart disease risk in senior women

Researchers found that daily life movement, including housework and self-care activities, significantly benefits cardiovascular health. Women with at least four hours of daily life movement had a 43% lower risk of cardiovascular disease, 62% lower risk of cardiovascular disease death.

SourceUniversity of California - San Diego·JournalJournal of the American Heart Association·TypeObservational study·DateFeb 22, 2022
Sony Alpha a7 IV (Body Only)

Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.