Articles tagged with Lung Cancer
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A new study published in the Journal of the National Comprehensive Cancer Network (JNCCN) found that incorporating the Electronic Health Record-Enabled Evidence-Based Smoking Cessation Treatment (ELEVATE) program into electronic health records can significantly improve smoking cessation rates among cancer patients. The research demonst...
A new study from McGill University finds that people living near regions prone to wildfires may have a higher incidence of lung cancer and brain tumors. Exposure to carcinogenic wildfire pollutants on a chronic basis increases the risk of certain cancers, according to researchers.
A systematic review and meta-analysis of 81 studies found that COVID-19 patients with cancer had a higher risk of death compared to those without cancer. Younger age, lung, and hematologic cancers were identified as risk factors for poor outcomes from COVID-19
A team of researchers used a CRISPR-based approach to study the evolution of lung cancer cells, tracking their history from the first activation of cancer-causing mutations. The study revealed significant diversity between subpopulations of cells within the same tumor, with certain groups becoming more fit and aggressive over time.
Canada's cancer rates are declining overall, but new cases and deaths are on the rise due to an aging population and growing numbers. Despite this, efforts in cancer prevention, screening, early detection, and treatment have led to improved survival rates for those diagnosed with cancer.
A recent study presented at the 2022 ARRS Annual Meeting found that COVID-19 infection significantly impacted lung cancer screening in diverse inner-city populations. The research revealed that approximately 9% of participants developed COVID-19 during the pandemic, with mortality rates reaching 6.9%.
Researchers developed a model using radiomic features from screening images to identify high-risk lung cancer patients. The model divided patients into groups according to their risk of having poor outcomes, with low-risk patients having an 83.3% five-year overall survival and high-risk patients having a 25% five-year overall survival.
Michelle Williams, Assistant Professor at George Mason University, received $9,999 to host a lung cancer screening webinar series targeting healthcare providers in Mississippi. The goal is to decrease lung cancer incidence and mortality rates through increased screenings and smoking cessation.
A new study by Vanderbilt University researchers has cast doubt on the impact of a proposed ban on menthol-flavored tobacco cigarettes. The study found no statistically significant difference in quit rates between menthol and non-menthol smokers, despite earlier reports that menthols were harder to quit. The study's authors suggest cau...
A study in eLife found that fine air pollution particles can increase the risk of lung cancer by altering lung tissue structure and reducing immune cell infiltration. The researchers identified peroxidasin as a key enzyme responsible for this effect, which could lead to new approaches for preventing or treating lung disease.
A retrospective study found that higher coronary artery calcium score, higher pulmonary artery-to-aorta ratio, and lower thoracic skeletal muscle index independently predicted worse overall survival. The PA-to-aorta ratio was the most important predictor of overall survival.
Researchers at Purdue University discovered that some lung cancer patients become resistant to common therapeutics due to epigenetic regulation of the KMT5C gene. This understanding lays the groundwork for future therapeutics and provides insight into the biology and progression of cancers.
A study published in the Ochsner Journal found that 28.2% of current smokers reported increased tobacco use during the pandemic, while former smokers experienced no relapse. Researchers identified correlates of increased tobacco use, including mental health concerns and coping strategies.
Researchers identified rural Georgia counties with high mortality rates from breast, prostate, colorectal, and lung cancer. These hotspots were concentrated in the eastern Piedmont to southern Coastal Plain regions, as well as southwestern and northern rural areas.
A recent study led by scientists at Albert Einstein College of Medicine suggests that some smokers have robust mechanisms to limit mutations, protecting them from lung cancer. The findings could help identify those with an increased risk for the disease and warrant close monitoring.
Adding immunotherapy to chemotherapy before surgery reduced the risk of recurrence and death in lung cancer patients by 37%, according to a phase III trial. The treatment also led to a nearly twelvefold increase in pathological complete response, with 24% of patients achieving no active cancer remaining when the tumor was removed.
A phase two randomised placebo controlled trial showed giving patients nintedanib, as well as chemotherapy before surgery or radiotherapy, significantly increased overall survival rates at one, two and five years. Nintedanib blocks different proteins from sending signals to cancer cells to grow, causing the cancer cells to die.
The CodeBreaK 100 trial demonstrated prolonged tumor responses and favorable safety profiles in patients treated with sotorasib. Long-term treatment was well-tolerated, with a two-year overall survival rate of 32.5%.
Researchers identified a genetic variant associated with increased response to anti-PD-1 therapy and higher immune-related side effects in lung cancer patients. The variant, found in 15.7% of exceptional responders, may be used to identify patients who would benefit from treatment.
Raising awareness about cardiac radiation exposure reduced the number of patients receiving high heart doses in lung cancer patients. The study found that standardized cardiac dose constraints improved patient care without minimizing tumor treatment or increasing dosage to other at-risk organs.
Researchers have identified a process to study circulating tumor cells responsible for cancer recurrence in patients with non-small cell lung cancer. The study models showed that these cells correlated with cancer recurrence, and blocking a protein called MYC made the tumor cells more vulnerable to chemotherapy.
The American Association for Cancer Research (AACR) has announced the recipients of its 2022 Scientific Achievement Awards and Lectureships, recognizing Tony Hunter, Christina Curtis, John E. Dick, Kevan M. Shokat, and Lee M. Ellis for their groundbreaking contributions to cancer research.
The study reveals a narrowing gap between cancer profiles in China and the USA, with converging trends in lung, breast, and colorectal cancers. China's cancer burden is expected to rise, while the US has seen reduced rates since the 1990s due to effective prevention strategies.
A new study finds that lung cancer screening is less common among those with poor health, with racial and ethnic disparities evident despite potential benefits. Non-Hispanic Black individuals are nearly half as likely to report lung cancer screening as non-Hispanic White individuals.
Lung cancer screening in the US has been associated with increased early detection of non-small cell lung cancer and improved survival rates. However, disparities in access to screening remain, with economically deprived areas and racial/ethnic minority groups showing reduced benefits.
Researchers developed a method to identify aggressive early-stage lung cancers and target drugs to tumors likely to respond. They used genomics network models and identified signature genes associated with tumor invasiveness.
A Spanish national registry study found that over half of diagnosed lung cancer patients undergo biomarker testing, with a significant increase over the last five years. Nearly half of patients with positive test results received targeted treatment.
A consensus reached by a lung clinical community highlighted international disparities in management and outcomes of patients with lung cancer. The roadmap provides key actions to homogenize practices, facilitate earlier diagnosis, and offer equitable access to care.
A team of researchers led by Tejas Patil is investigating how the EGFR and MET signaling pathways contribute to treatment resistance in RET-positive lung cancer. The study aims to determine whether combining a RET-targeted therapy with amivantamab, a bi-specific antibody blocking both pathways, can improve patient outcomes.
A new study reveals that the COVID-19 pandemic has led to significant declines in cancer screening rates across the US, particularly for colorectal, cervical, breast, and lung cancers. The American Cancer Society's National Consortium has announced nine recommendations to increase cancer screening rates and improve quality care.
Researchers have created a 'worm-on-a-chip' device that uses roundworms to detect lung cancer cells, showing 70% accuracy. The device could potentially help doctors diagnose cancer at an earlier stage non-invasively.
Researchers at Weill Cornell Medicine have found that an enzyme called ART1 can modify a receptor on tumor-fighting immune cells, triggering their death. Blocking ART1 increased the presence of these immune cells within tumors and slowed or stopped tumor growth in animal models.
The European Lung Cancer Congress 2022 focused on the latest advancements in lung cancer treatment, including personalized strategies for better patient care. The congress also explored emerging therapies and molecular sub-types to enhance precision medicine.
Two clinical trials will report groundbreaking data on adjuvant olaparib for germline BRCA1/2 associated breast cancer and pembrolizumab for early-stage non-small cell lung cancer. These treatments aim to improve survival rates and reduce recurrence.
The Southeastern Consortium for Lung Cancer Health Equity aims to address disparities in lung cancer screening among racially and ethnically diverse populations. Researchers will develop more precise methods for identifying those at highest risk of lung cancer diagnoses.
A new study found that dual-eligible patients for Medicare and Medicaid have poorer outcomes and higher costs after cancer surgery, even in high-quality hospitals. These patients are more likely to experience complications, longer hospital stays, and lower chances of going home instead of a nursing facility.
Researchers have discovered that cancer cells carrying a common mutation accumulate large amounts of ferrous iron, which can be exploited to deliver powerful anticancer drugs. The therapeutic strategy could treat various cancers driven by KRAS mutations.
A new fluorescent DNA label has been developed to visualize disrupted DNA architecture in cancer cells, with promising results for improved cancer diagnoses and risk stratification. The study showed that the label can distinguish normal tissue from precancerous and cancerous lesions.
A recent review of e-cigarette research highlights the significant health risks associated with vaping, including lung inflammation and injury. The study found that e-cigarettes can cause negative effects in multiple organs, from the brain to the bladder, and may even increase the risk of lung cancer.
The ATS 2022 International Conference will take place in San Francisco from May 15-18, featuring a gathering of scientists and clinicians in pulmonary, critical care, and sleep medicine. The conference will showcase accelerated research and clinical applications across lung diseases, including COVID-19.
Researchers from the University of Barcelona discovered that embryonic development signals can also control cancer cell growth, inhibiting proliferation and inducing differentiation in lung cancer cells. The study's findings have implications for developing new therapeutic strategies to fight lung cancer.
A multi-faceted intervention resulted in timelier lung cancer surgery for Black patients, with median times of 23 days compared to 43 days for historical groups. The ACCURE trial improved treatment rates and reduced treatment delays, demonstrating the effectiveness of addressing racial inequities in care.
New studies from Michigan Medicine researchers aim to remove financial barriers for patients who receive abnormal test results, enabling them to complete the diagnostic process. The findings suggest that removing cost barriers could save lives by increasing screening uptake, particularly among women and underserved populations.
Paczesny will explore biomarkers and a new type of immune cell to identify and regulate acute lung injury after BMT. She aims to improve understanding of signaling mechanisms in lung injury after BMT, particularly as they relate to idiopathic pneumonia syndrome.
Researchers have developed a new therapeutic approach to block mutated RAS proteins, which are frequently found in cancers. The method, using small molecules, has the potential to work with multiple mutant forms of RAS in various types of cancers, including pancreatic, lung, and colorectal cancers.
A study found that lung cancer patients coped better with the pandemic, showing lower levels of anxiety and depression compared to healthy individuals. The strength needed to face their disease helped them cope more effectively with COVID-19 fears.
A recent study published in Developmental Cell reveals that Kras mutation causes chromatin rearrangement, leading to stem-like cell regeneration and tumor onset. The team discovered a protein complex called AP-1 as the mediator of this process, which can be targeted with small-molecule drugs.
A new study found that Hong Kong's remote sensing enforcement program significantly reduced harmful chemicals at the roadside and in the atmosphere. The program led to a 22-39% reduction in total hydrocarbons, carbon monoxide, and nitric oxide emissions from high-emitting vehicles.
The ACC cardiooncology course is designed to educate clinicians on improving awareness, identification, monitoring, and management of cardiovascular diseases in cancer patients. The course aims to help clinicians minimize cardiotoxicity from cancer therapies, leading to improved overall survival and quality of life for oncology patients.
Dr. John Pierce Wise leads a team to investigate chromosome instability in lungs caused by metal exposure, with hopes of preventing and reversing lung cancer in people. The research aims to understand why humans are more susceptible to metals-induced lung cancer than whales.
Ovarian cancer death rates are predicted to decrease by 17% in the UK and 7% in EU countries in 2022. The main contributor is the long-term use of oral contraceptives, reducing the risk by 40%. Other factors include improved diagnosis, treatment, and advancements in treatments for other cancers.
A study found that lung cancer screening among non-smoking women in Taiwan has led to a 6-fold increase in early-stage diagnoses, while late-stage cancer and death rates remain stable. The researchers estimate that between 7,000 and 12,000 Taiwanese women have been overdiagnosed with lung cancer.
Four MUSC Hollings Cancer Center researchers received American Cancer Society Institutional Research Grants worth $35,000 each. The grants support promising projects that aim to push cancer care forward. Researchers are working on various innovative projects, including a digital literacy training program for community health workers an...
A recent study by Wayne State University School of Medicine found that updated guidelines improve eligibility for lung cancer screenings across various racial groups. The research reveals a significant reduction in racial disparities in accessing screening services.
Dr. Mark S. Parker, MD, FACR, has been recognized as the 2022 ARRS Distinguished Educator for his outstanding contributions to radiological education. He will be formally recognized at the ARRS Annual Meeting in New Orleans, LA on May 1, 2022.
A blood test combining a four-marker protein panel with an independent model improves lung cancer risk assessment, identifying 9.2% more cases for screening and reducing referrals by 13.7%. The study shows the potential to determine who may benefit from lung cancer screening with improved accuracy.
Researchers at Massachusetts General Hospital found that inhibiting the OR5B21 gene significantly decreased breast cancer metastasis to the brain, bones and lung. This discovery may lead to new therapeutic targets to prevent or delay breast cancer's spread.
A recent study found that a substantial decline in lung cancer deaths is associated with earlier diagnosis of lung cancer through increased screening via computed tomography (CT) and follow-up scans. This approach can lead to surgical interventions, which can often be curative for precancerous nodules.
Researchers are part of a five-year global study examining the behavioral and long-term health impacts of different regulatory approaches to e-cigarettes and other new nicotine products among youth and adults in seven countries. The study aims to inform US public policy based on evidence, maximizing population health.
A predictive model based on magnetic resonance spectroscopy can detect lung cancer from alterations in blood metabolites, allowing for early-stage screening and potentially improving survival rates. The study screened tens of thousands of blood specimens and found accurate predictions using values from prior-to-diagnosis blood samples.