Articles tagged with Gestational Age
A large Norwegian study found that people born preterm are less physically active as teenagers and adults. The study, which measured physical activity using wearable sensors, suggests that preterm birth may be associated with reduced physical activity in young adulthood.
Researchers have identified a potential new target for preventing preterm labour, targeting a specific group of proteins in the uterus muscle that can suppress human uterine contractions and delay preterm birth in a preclinical model. The study, published in Communications Medicine, highlights a promising avenue for developing new drug...
After the Dobbs v Jackson decision, out-of-state travel to North Carolina for abortion care increased, particularly from more restrictive Southeastern states. Patients also presented at later gestational durations and traveled farther for care, indicating increased logistical barriers after policy changes.
Researchers found that treating women with Lactobacillus gasseri supplements or postbiotics improved fertility among those over 35. The study showed higher endometrial abundance of Lactobacillus bacteria in pregnant women, suggesting a beneficial effect on uterine health.
A randomized clinical trial in South Delhi, India found that an integrated package of health, nutrition, and early stimulation support significantly improved the growth of term small-for-gestational-age infants. Infants who received this intervention had a higher weight at 12 months compared to those receiving usual government care.
A major new study suggests that age-related changes in the uterus may contribute to poorer pregnancy outcomes, with women aged 49 and over experiencing lower live birth rates and higher miscarriage risk despite donor-oocyte treatment. The study found that cumulative live birth rates declined substantially with age, from 80% among women...
The study found that gestational exposure to 10 classes of priority chemicals was associated with differences in gestational age at birth and lower birth weight-for-gestational age z scores. Reducing exposure to these chemicals could promote healthy deliveries and better child outcomes.
A WVU study found that pregnant women who spend more time sitting are at a greater risk of developing gestational diabetes and preeclampsia. Sitting for over 10 hours a day was associated with twice as many adverse pregnancy outcomes as shorter periods of sitting.
A study published in JAMA found that sitting less with greater light-intensity movement and steps was associated with significantly lower risks of adverse pregnancy outcomes. Adverse pregnancy outcomes include hypertensive disorders, gestational diabetes, preterm birth, and small for gestational age
A longitudinal study found that mothers with hypertensive disorders during pregnancy had children with suboptimal cardiovascular health and arterial injury in early adulthood. Optimizing pregnancy health may support offspring cardiovascular well-being.
Researchers suggest treatment could start during pregnancy to prevent brain damage and reduce neurological harm. A new RNA-based therapy reduces abnormal electrical currents in patient-derived excitatory neurons.
A study by King's College London found that babies exposed to high levels of air pollution in the womb show slower signs of development at 18 months compared to those exposed to lower levels. This is particularly true for premature babies, who experience poorer motor and language skills.
Researchers found a 21% increased risk of all stroke events for individuals with low birthweight compared to those above median weight. Low birthweight was also linked to increased risks of ischemic and intracerebral hemorrhage strokes, independent of gestational age and BMI.
The study found that women with pregnancy-associated spontaneous coronary artery dissection (P-SCAD) have a higher risk of cardiovascular events, including dissections and aneurysms. Women with P-SCAD also experienced less recovery in left ventricular ejection fraction compared to those without P-SCAD.
Eating ultra-processed foods is associated with slower embryo growth, smaller yolk sacs, and increased subfertility risk. Reducing UPF consumption around conception and pregnancy may improve fertility outcomes for both parents and embryos.
Cohort study finds prenatal depression and gestational diabetes independently increase childhood obesity risk, while children exposed to both face the greatest risk, highlighting need for universal screening and targeted interventions.
A study reveals that senescence plays a paradoxical role in postpartum breast cancer, promoting tumor formation while also aiding tissue repair. Targeting senescent cells during mammary gland involution could potentially reduce the risk of this form of cancer.
Research finds that SSRIs during pregnancy increase gestational diabetes risk in newborns but lower preterm birth and low birth weight risks. SSRIs also associated with breathing problems and neonatal care needs in newborns.
The study found increased requests for medication abortion among adolescents in states with gestational bans and parental consent requirements. Young adults also sought more medication abortion services post-Dobbs, with the highest demand in states with restrictive abortion laws.
A preclinical study shows that cannabidiol restores emotional behavior, reduces alcohol-related vulnerability, and reverses gut microbiota alterations caused by prenatal alcohol exposure. Female mice particularly benefited from CBD treatment, which normalized their emotional alterations and eliminated vulnerability to alcohol addiction.
A cohort study found higher fine particulate matter (PM2.5) exposure associated with lower birth weight, particularly in early and mid-pregnancy. The study's findings suggest that understanding windows of susceptibility to environmental exposures can inform strategies for limiting exposure during critical periods.
A recent study published in JAMA found that initiating resuscitation of preterm infants with fraction of inspired oxygen levels of 0.6 versus 0.3 did not affect the risk of death or brain injury by 36 weeks' corrected gestational age.
A study found that women with obesity who stopped using GLP-1 receptor agonists experienced more gestational weight gain and a higher risk of preterm delivery, gestational diabetes, and hypertensive disorders. The research suggests that discontinuation of these medications may impact pregnancy outcomes.
Dr. Leanne Redman joins the Charles Perkins Centre to lead research on obesity, diet, and exercise, building on her extensive experience in women's health issues and translational research. With over 300 publications and numerous awards, she will expand the centre's impact on global health.
A new study from University of California Merced found that married fathers' optimism and confidence can lower maternal inflammation during pregnancy, leading to longer gestation periods. Higher paternal resilience also predicted healthier fetal development.
A new Harvard study found that US stillbirth rates are higher than previously reported, with many cases having no identified clinical risk factor. The study highlights the need for improved stillbirth risk prediction and prevention efforts.
A large national cohort study found associations between adverse pregnancy outcomes and increased risk of atrial fibrillation up to 46 years later. Women with these outcomes require early preventive actions and long-term clinical follow-up.
Full-term children exposed to antenatal corticosteroids are at higher risk of infections until age 21, a new study finds. Preterm children, however, show no association between ACS and infections.
Researchers at Stowers Institute for Medical Research have identified the precise location where human chromosomes break and recombine to form Robertsonian chromosomes. The study reveals that repetitive DNA sequences play a central role in genome organization and evolution, explaining how these rearrangements form and remain stable.
The global study found that women are having babies later in life, increasing health risks and widening inequalities in maternal care. The average age of first-time mothers has steadily increased, with many now starting their families aged 35 years or over.
A large-scale study found strong links between maternal infections and adverse outcomes in babies born in Australia's Northern Territory. Congenital syphilis tripled the risk of preterm birth, while gonorrhoea increased the risk of stillbirth. The study highlights the need for more changes in STI testing during pregnancy.
Children of older mothers are more likely to be born prematurely or with complications. The study found that babies born to mothers 45 years and older had the highest risks of stillbirth, premature birth, and low birth weight compared to younger mothers.
A recent USC study found associations between increased exposure to wildfire smoke and heat stress during preconception and the first trimester with the odds of having a small-for-gestational-age infant. Living in a climate-vulnerable neighborhood can increase these risks, particularly for women exposed to heat stress.
A systematic review found a moderate risk of preterm birth, low birth weight, and infant death associated with cannabis use during pregnancy. Researchers recommend reducing cannabis use as a harm-reduction approach to mitigate risks.
A recent study published in JAMA Pediatrics found that prenatal cannabis use is associated with an increased risk of preterm birth and low birth weight. The research also suggests a potential link between cannabis use during pregnancy and smaller-than-average newborns.
A cross-sectional study found that moderately preterm birth was associated with long-term cognitive problems. The study highlights the need for continued follow-up of all preterm children, particularly those born before 34 weeks' gestational age.
Researchers at West Virginia University found that babies born to teen mothers weigh less and are smaller for their gestational age. The study highlights the role of social, geographical, and educational factors in teen pregnancy prevention.
Researchers analyzed data from 8,843 women with preeclampsia to evaluate the performance of existing risk prediction models. The study found that these models are most accurate only in the days following diagnosis and deteriorate over time.
A cohort study found that individuals with higher radon exposure are at a greater risk of developing gestational diabetes during pregnancy. The study suggests a potential link between radon exposure and metabolic health in nulliparous pregnant women.
A new study finds that women with gestational hypertension and preeclampsia are at increased risk of developing new-onset migraine, headache, epilepsy, sleep disorder, or mental fatigue after giving birth. Follow-up care is recommended for these high-risk patients to monitor for neurological symptoms.
New research reveals racial differences in mortality rates, with Black newborns facing higher risks of necrotizing enterocolitis and late-onset sepsis. Addressing social determinants of health is critical for promoting health equity in hospital outcomes.
Women with gestational diabetes who engaged in moderate-to-vigorous intensity physical activity during pregnancy had a lower risk of preterm birth compared to those who were less active. Concentrated periods of physical activity also offered similar benefits in reducing preterm birth risk.
A population-based matched cohort study found that preterm birth is associated with higher mortality risks until the third and fourth decades of life. These findings suggest that preterm birth should be recognized as a risk factor for mortality, informing preventive strategies.
A large cohort study found that early exposure to air pollutants like PM2.5 and nitrogen oxides can alter the development of white matter in the brain, with some effects persisting throughout adolescence.
A recent Cochrane review confirms that giving women at risk of premature birth a simple magnesium sulphate infusion can prevent their babies from developing cerebral palsy. The drug costs approximately £5 (~$6.50) per dose and has been recommended by the World Health Organization since 2015.
A Northwestern University study reveals that states with severe post-Dobbs abortion restrictions also lack policies to support families, particularly those of low socioeconomic status and marginalized individuals. The authors argue that advocates should leverage child protection arguments to advocate for improved family welfare policies.
A novel AI tool has been shown to accurately estimate gestational age from blind ultrasound sweeps, comparable to expert sonographers. The technology has the potential to democratize prenatal care in resource-limited settings by expanding access to quality diagnostic tools without the need for expensive equipment or specialized training.
A study of 1,106 newborns from five countries found that prenatal exposure to ethylene oxide is associated with lower birth weight and smaller head circumference. The results suggest that reducing exposure to ethylene oxide could protect fetal health and improve birth outcomes.
Researchers at Dartmouth College found that fruit fly oocytes can renew chromosome-linking proteins, potentially helping older women reduce pregnancy complications. The discovery could lead to new therapeutic strategies for enhancing protein rejuvenation in human eggs.
After the Dobbs ruling, more people traveled from out of state for abortion care. In-state patients waited a week longer to receive care. These findings can inform access-improving interventions and policies.
A Swedish study published in JAMA Network Open found that over one million newborns were given unnecessary antibiotics for suspected sepsis despite a reduction in sepsis cases. The researchers argue that the treatment burden is too high, suggesting potential to reduce antibiotic use.
A national cohort study of over 2 million Swedish women found that those experiencing five major adverse pregnancy outcomes had significantly higher mortality rates. The study highlights the importance of early preventive evaluation and long-term follow-up for detection and treatment of chronic disorders associated with premature morta...
A recent NIH study found that living in low-income neighborhoods with limited food access during pregnancy is associated with lower birthweight and higher odds of babies born small for gestational age. However, individual food insecurity was not linked to birth outcomes.
Researchers found associations between prenatal vitamin and metal exposures and epigenetic aging biomarkers in early life. A one standard deviation increase in essential metals was associated with lower Horvath EAA at birth, while arsenic was linked to greater EAA at birth and in childhood.
A study published in Lancet eClinical Health found pregnancy outcomes for pregnant individuals with autoimmune disease vary greatly depending on the specific condition and individual factors. Research highlights the importance of considering comorbidities when discussing autoimmune disease and pregnancy.
A new study by Northwestern University found that lab-trained AI models are easily misled by tissue contaminants, resulting in errors in diagnoses and vessel damage detection. The researchers suggest improving the problem of quantifying and addressing biological impurities in AI models to enhance accuracy.
A large-scale study found exposure to low and high biothermal stress during pregnancy linked to a higher risk of babies being born too small or large for their gestational ages. The study also identified specific subpopulations at higher risk, including non-Caucasian people and those aged 35 and above.
A recent study published in JAMA Network Open analyzed data from 10,000 US adolescents and found a significant increase in e-cigarette use during late pregnancy. However, the study revealed no statistically significant association between e-cigarette use and an increased risk of small-for-gestational-age birth among adolescents.
A study published in PLOS Medicine found that 90% of pregnant women in high-income countries lack key vitamins necessary for healthy pregnancies and fetal development. The situation is expected to worsen as more people adopt plant-based diets, leading to increased risk of nutrient deficiencies.
Researchers found that delivering at 39 weeks reduced perinatal risk in term singleton pregnancies conceived through infertility treatment. This study suggests a specific gestational age for optimal birth outcomes in these cases.