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Fathers’ psychiatric diagnosis increases risk of preterm birth

A new analysis of Swedish birth records found that fathers' psychiatric diagnoses increase the risk of preterm birth, with risks higher for infants whose parents have both diagnoses. The study suggests that additional social support and prenatal care may help mitigate this risk.

SourcePLOS·JournalPLOS Medicine·TypeObservational study·DateJul 20, 2023

THE LANCET: An estimated one million stillbirths and newborn baby deaths could be prevented each year by implementing low-cost pregnancy interventions in low- and middle-income countries

Eight low-cost interventions can prevent an estimated 566,000 stillbirths and 5.2 million babies born preterm or small for gestational age each year. Implementing these interventions in 81 low- and middle-income countries could save the lives of millions of babies and improve long-term health outcomes.

SourceThe Lancet·JournalThe Lancet·DateMay 8, 2023

New study reveals pregnant people who deliver large babies are at increased risk of developing diabetes later in life

A new study found that pregnant individuals who give birth to large-for-gestational-age (LGA) babies are at a higher risk of developing prediabetes or Type 2 diabetes 10-14 years after childbirth. Researchers analyzed data from the Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study, which revealed a significant association bet...

WVU study shows number of West Virginia infants exposed to drugs in the womb is 10 times higher than national rate

A new WVU study found nearly one in eight West Virginia infants had in utero exposure to opioids, stimulants, and/or cannabis between 2020 and 2022. The study showed a 40% increased risk of preterm birth among infants exposed to stimulants alone and a 70% increase with concurrent stimulant and cannabis exposures.

SourceWest Virginia University·JournalThe Journal of Pediatrics·DateFeb 7, 2023

Buprenorphine, not methadone, may be safer treatment for opioid-use disorder during pregnancy

Researchers found that buprenorphine use was associated with better outcomes for the baby, including lower risk of preterm birth, small size for gestational age, and low birth weight. The study suggests increasing access to buprenorphine treatment among pregnant individuals with opioid-use disorder.

SourceRutgers University·JournalNew England Journal of Medicine·TypeData/statistical analysis·DateNov 30, 2022

Infants who die unexpectedly in the first week might have different risk factors than those who die in the first month

A Rutgers study found that infants who died unexpectedly in the first week of life had different risk factors compared to those who died later. The study analyzed data from 2000 to 2015 and found that mothers of infants dying in the first week showed less evidence of common risk factors such as smoking during pregnancy.

SourceRutgers University·JournalThe Journal of Maternal-Fetal & Neonatal Medicine·TypeData/statistical analysis·DateOct 20, 2022

COVID-19 vaccination during pregnancy

COVID-19 vaccination during pregnancy was found to lower the risk of severe outcomes including preterm birth and postpartum hemorrhage. Vaccination during pregnancy is now recommended to protect against COVID-19 infection.

SourceJAMA Network·JournalJAMA Pediatrics·DateOct 3, 2022

Colonoscopies in FIT-positive persons requires much higher ADR than primary colonoscopy

A cohort study found that endoscopists performing colonoscopies in FIT-based screening programs should aim for markedly higher ADRs compared to primary colonoscopy screening. The study suggests that high ADRs are associated with lower colorectal cancer incidence and mortality. Researchers recommend using ADR targets, including differen...

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeObservational study·DateSep 26, 2022

Nano-preterm infants may not benefit from noninvasive versus invasive ventilation at birth

Researchers at the University of Alabama at Birmingham found that noninvasive ventilation in nano-preterm infants did not show an advantage in reducing bronchopulmonary dysplasia or death. In contrast, infants who received invasive respiratory support had lower rates of severe intraventricular hemorrhage and death.

SourceUniversity of Alabama at Birmingham·JournalJAMA Network Open·TypeCase study·DateSep 6, 2022

New research shows no link between COVID-19 vaccination during pregnancy and higher risk of preterm birth or stillbirth

A population-based retrospective cohort study found that COVID-19 vaccination during pregnancy is not associated with an increased risk of preterm birth, small for gestational age at birth, or stillbirth. The study concluded that COVID-19 vaccination during pregnancy can inform evidence-based decision-making about its safety.

SourceUniversity of Ottawa·JournalThe BMJ·TypeData/statistical analysis·DateAug 29, 2022

Arsenic in private well water contributes to low birth weight even at low levels

Researchers found an association between estimated groundwater arsenic concentration and risk of low birth weight, suggesting efforts to reduce arsenic in private wells could help more babies be born at healthy weights. The study used machine learning algorithms to estimate arsenic levels in nearly all US counties.

SourceUniversity of Illinois Chicago·JournalEnvironment International·TypeData/statistical analysis·DateJun 24, 2022

Obese pregnant women are more likely to experience stillbirth or neonatal death, and over 60 percent of this increased risk is associated with delivery occurring at an earlier gestational age

A recent study found that obese pregnant women are at a higher risk of experiencing stillbirth or neonatal death. The research revealed that over 60% of this increased risk is associated with deliveries occurring at an earlier gestational age, highlighting the importance of careful prenatal care and monitoring.

SourcePLOS·JournalPLOS ONE·DateMar 23, 2022

UK stillbirths among black and South Asian communities still double those of rest of population

Despite an overall decline in stillbirth rates across the UK, black and South Asian communities continue to experience higher rates of stillbirths compared to the rest of the population. Placental issues and birth defects are key causes of stillbirths in these groups, but the underlying cause remains unknown in more than half of cases.

SourceBMJ Group·JournalBMJ Open·TypeData/statistical analysis·DateMar 8, 2022

Smoking before and after conception is linked to delayed embryonic development

A study published in Human Reproduction found that smoking by mothers during the periconceptional period is associated with delayed embryonic development, smaller foetuses at the 20-week ultrasound scan, and lower birth weights. The delay in embryonic development was found to have a greater impact in the second trimester of pregnancy.

SourceEuropean Society of Human Reproduction and Embryology·JournalHuman Reproduction·TypeObservational study·DateFeb 22, 2022

An NICU quality-improvement program reduced death or severe brain bleeding in extremely premature infants

A comprehensive quality-improvement initiative in a NICU reduced death and severe brain bleeding in extremely preterm infants from 27.4% to 15%. The program introduced evidence-based practices, including electronic order sets, improved monitoring of blood carbon dioxide and pH levels, and standardized delivery room practices.

SourceUniversity of Alabama at Birmingham·JournalPEDIATRICS·TypeExperimental study·DateFeb 3, 2022

Smoking whilst pregnant linked to smaller babies in future pregnancies

A recent study published in PLOS ONE found that smoking during pregnancy can increase the risk of having a small for gestational age (SGA) baby in subsequent pregnancies. The research analyzed data from nearly 17,000 mothers who received antenatal care for their first two pregnancies and found that women who smoked at the start of eith...

SourceUniversity of Southampton·JournalPLOS ONE·TypeData/statistical analysis·DateNov 29, 2021

Antipsychotics during pregnancy

This observational study found no association between prenatal antipsychotic exposure and increased risk of preterm birth, attention-deficit/hyperactivity disorder (ADHD), and autism spectrum disorder in children. The study's findings suggest that antipsychotics during pregnancy do not pose a significant risk to fetal development.

SourceJAMA Network·JournalJAMA Internal Medicine·DateAug 16, 2021

Small increase in risk of autism seen for pre- and post-term births

A study of over 3.5 million Nordic children found a slight increase in autism risk for each week of gestation before or after 40 weeks, regardless of sex or birth weight. The relative risk was highest for children born at 22-31 weeks and lowest for those born post-term (after 42 weeks), with an overall low ASD incidence of 1.44%.

SourcePLOS·JournalPLOS Medicine·DateSep 22, 2020

A smartphone and new software could help save infants born preterm

A new machine learning algorithm combined with a handheld smartphone device can accurately estimate the gestational age of premature newborns. The technology has the potential to aid healthcare workers in remote and low-income countries, where preterm births are a leading cause of child mortality.

SourceOptica·JournalBiomedical Optics Express·DateNov 20, 2018

True burden of stillbirths in Europe vastly underestimated

A study of 2.5 million babies in 19 European countries found that around one-third of stillbirths occur before 28 weeks of pregnancy but are not officially recognized, with significant gaps in knowledge of the burden of stillbirth. Improvements in reporting and policy can help acknowledge the loss of these parents' children.

SourceThe Lancet·JournalThe Lancet·DateSep 27, 2018

Gestational age measured via DNA methylation

Researchers developed a method estimating developmental maturity via DNA methylation patterns, which can help assess preterm newborns' care and estimate conception time. The study found gestational age accurately estimated between 24-44 weeks, with correlations to birthweight and developmental maturity.

SourceEmory Health Sciences·JournalGenome Biology·DateOct 10, 2016