Articles tagged with Gestational Age
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A preclinical study shows that cannabidiol restores emotional behavior, reduces alcohol-related vulnerability, and reverses gut microbiota alterations caused by prenatal alcohol exposure. Female mice particularly benefited from CBD treatment, which normalized their emotional alterations and eliminated vulnerability to alcohol addiction.
A cohort study found higher fine particulate matter (PM2.5) exposure associated with lower birth weight, particularly in early and mid-pregnancy. The study's findings suggest that understanding windows of susceptibility to environmental exposures can inform strategies for limiting exposure during critical periods.
A recent study published in JAMA found that initiating resuscitation of preterm infants with fraction of inspired oxygen levels of 0.6 versus 0.3 did not affect the risk of death or brain injury by 36 weeks' corrected gestational age.
A study found that women with obesity who stopped using GLP-1 receptor agonists experienced more gestational weight gain and a higher risk of preterm delivery, gestational diabetes, and hypertensive disorders. The research suggests that discontinuation of these medications may impact pregnancy outcomes.
Dr. Leanne Redman joins the Charles Perkins Centre to lead research on obesity, diet, and exercise, building on her extensive experience in women's health issues and translational research. With over 300 publications and numerous awards, she will expand the centre's impact on global health.
A new study from University of California Merced found that married fathers' optimism and confidence can lower maternal inflammation during pregnancy, leading to longer gestation periods. Higher paternal resilience also predicted healthier fetal development.
A new Harvard study found that US stillbirth rates are higher than previously reported, with many cases having no identified clinical risk factor. The study highlights the need for improved stillbirth risk prediction and prevention efforts.
A large national cohort study found associations between adverse pregnancy outcomes and increased risk of atrial fibrillation up to 46 years later. Women with these outcomes require early preventive actions and long-term clinical follow-up.
Full-term children exposed to antenatal corticosteroids are at higher risk of infections until age 21, a new study finds. Preterm children, however, show no association between ACS and infections.
Researchers at Stowers Institute for Medical Research have identified the precise location where human chromosomes break and recombine to form Robertsonian chromosomes. The study reveals that repetitive DNA sequences play a central role in genome organization and evolution, explaining how these rearrangements form and remain stable.
The global study found that women are having babies later in life, increasing health risks and widening inequalities in maternal care. The average age of first-time mothers has steadily increased, with many now starting their families aged 35 years or over.
A large-scale study found strong links between maternal infections and adverse outcomes in babies born in Australia's Northern Territory. Congenital syphilis tripled the risk of preterm birth, while gonorrhoea increased the risk of stillbirth. The study highlights the need for more changes in STI testing during pregnancy.
Children of older mothers are more likely to be born prematurely or with complications. The study found that babies born to mothers 45 years and older had the highest risks of stillbirth, premature birth, and low birth weight compared to younger mothers.
A recent USC study found associations between increased exposure to wildfire smoke and heat stress during preconception and the first trimester with the odds of having a small-for-gestational-age infant. Living in a climate-vulnerable neighborhood can increase these risks, particularly for women exposed to heat stress.
A recent study published in JAMA Pediatrics found that prenatal cannabis use is associated with an increased risk of preterm birth and low birth weight. The research also suggests a potential link between cannabis use during pregnancy and smaller-than-average newborns.
A systematic review found a moderate risk of preterm birth, low birth weight, and infant death associated with cannabis use during pregnancy. Researchers recommend reducing cannabis use as a harm-reduction approach to mitigate risks.
A cross-sectional study found that moderately preterm birth was associated with long-term cognitive problems. The study highlights the need for continued follow-up of all preterm children, particularly those born before 34 weeks' gestational age.
Researchers at West Virginia University found that babies born to teen mothers weigh less and are smaller for their gestational age. The study highlights the role of social, geographical, and educational factors in teen pregnancy prevention.
Researchers analyzed data from 8,843 women with preeclampsia to evaluate the performance of existing risk prediction models. The study found that these models are most accurate only in the days following diagnosis and deteriorate over time.
A cohort study found that individuals with higher radon exposure are at a greater risk of developing gestational diabetes during pregnancy. The study suggests a potential link between radon exposure and metabolic health in nulliparous pregnant women.
A new study finds that women with gestational hypertension and preeclampsia are at increased risk of developing new-onset migraine, headache, epilepsy, sleep disorder, or mental fatigue after giving birth. Follow-up care is recommended for these high-risk patients to monitor for neurological symptoms.
New research reveals racial differences in mortality rates, with Black newborns facing higher risks of necrotizing enterocolitis and late-onset sepsis. Addressing social determinants of health is critical for promoting health equity in hospital outcomes.
Women with gestational diabetes who engaged in moderate-to-vigorous intensity physical activity during pregnancy had a lower risk of preterm birth compared to those who were less active. Concentrated periods of physical activity also offered similar benefits in reducing preterm birth risk.
A population-based matched cohort study found that preterm birth is associated with higher mortality risks until the third and fourth decades of life. These findings suggest that preterm birth should be recognized as a risk factor for mortality, informing preventive strategies.
A large cohort study found that early exposure to air pollutants like PM2.5 and nitrogen oxides can alter the development of white matter in the brain, with some effects persisting throughout adolescence.
A recent Cochrane review confirms that giving women at risk of premature birth a simple magnesium sulphate infusion can prevent their babies from developing cerebral palsy. The drug costs approximately £5 (~$6.50) per dose and has been recommended by the World Health Organization since 2015.
A Northwestern University study reveals that states with severe post-Dobbs abortion restrictions also lack policies to support families, particularly those of low socioeconomic status and marginalized individuals. The authors argue that advocates should leverage child protection arguments to advocate for improved family welfare policies.
A novel AI tool has been shown to accurately estimate gestational age from blind ultrasound sweeps, comparable to expert sonographers. The technology has the potential to democratize prenatal care in resource-limited settings by expanding access to quality diagnostic tools without the need for expensive equipment or specialized training.
A study of 1,106 newborns from five countries found that prenatal exposure to ethylene oxide is associated with lower birth weight and smaller head circumference. The results suggest that reducing exposure to ethylene oxide could protect fetal health and improve birth outcomes.
Researchers at Dartmouth College found that fruit fly oocytes can renew chromosome-linking proteins, potentially helping older women reduce pregnancy complications. The discovery could lead to new therapeutic strategies for enhancing protein rejuvenation in human eggs.
After the Dobbs ruling, more people traveled from out of state for abortion care. In-state patients waited a week longer to receive care. These findings can inform access-improving interventions and policies.
A Swedish study published in JAMA Network Open found that over one million newborns were given unnecessary antibiotics for suspected sepsis despite a reduction in sepsis cases. The researchers argue that the treatment burden is too high, suggesting potential to reduce antibiotic use.
A national cohort study of over 2 million Swedish women found that those experiencing five major adverse pregnancy outcomes had significantly higher mortality rates. The study highlights the importance of early preventive evaluation and long-term follow-up for detection and treatment of chronic disorders associated with premature morta...
A recent NIH study found that living in low-income neighborhoods with limited food access during pregnancy is associated with lower birthweight and higher odds of babies born small for gestational age. However, individual food insecurity was not linked to birth outcomes.
Researchers found associations between prenatal vitamin and metal exposures and epigenetic aging biomarkers in early life. A one standard deviation increase in essential metals was associated with lower Horvath EAA at birth, while arsenic was linked to greater EAA at birth and in childhood.
A study published in Lancet eClinical Health found pregnancy outcomes for pregnant individuals with autoimmune disease vary greatly depending on the specific condition and individual factors. Research highlights the importance of considering comorbidities when discussing autoimmune disease and pregnancy.
A new study by Northwestern University found that lab-trained AI models are easily misled by tissue contaminants, resulting in errors in diagnoses and vessel damage detection. The researchers suggest improving the problem of quantifying and addressing biological impurities in AI models to enhance accuracy.
A large-scale study found exposure to low and high biothermal stress during pregnancy linked to a higher risk of babies being born too small or large for their gestational ages. The study also identified specific subpopulations at higher risk, including non-Caucasian people and those aged 35 and above.
A recent study published in JAMA Network Open analyzed data from 10,000 US adolescents and found a significant increase in e-cigarette use during late pregnancy. However, the study revealed no statistically significant association between e-cigarette use and an increased risk of small-for-gestational-age birth among adolescents.
A study published in PLOS Medicine found that 90% of pregnant women in high-income countries lack key vitamins necessary for healthy pregnancies and fetal development. The situation is expected to worsen as more people adopt plant-based diets, leading to increased risk of nutrient deficiencies.
Researchers found that delivering at 39 weeks reduced perinatal risk in term singleton pregnancies conceived through infertility treatment. This study suggests a specific gestational age for optimal birth outcomes in these cases.
A study of over 500,000 children found no significant difference in math and reading scores between those born between 39-40 weeks' gestation and 41 weeks' gestation. The results inform decisions on delivery timing at term birth and long-term cognitive development.
A new analysis of Swedish birth records found that fathers' psychiatric diagnoses increase the risk of preterm birth, with risks higher for infants whose parents have both diagnoses. The study suggests that additional social support and prenatal care may help mitigate this risk.
A recent study of 106,000 births in New York City found that neighborhoods with healthier food options had lower rates of small for gestational age births. Higher densities of unhealthy food retail establishments were linked to increased risks of large or small-for-age birth weights.
Eight low-cost interventions can prevent an estimated 566,000 stillbirths and 5.2 million babies born preterm or small for gestational age each year. Implementing these interventions in 81 low- and middle-income countries could save the lives of millions of babies and improve long-term health outcomes.
A novel technique of three-dimensional (3D) slice-to-volume (SVR) MRI allows for precise delineation and measurement of the fetal optic pathway (FOP). The study found that FOP was visualized in 9 cases in unprocessed fetal MRIs, compared to 55 cases in 3D SVR images.
A new study by UC San Francisco found that taxes on sugary drinks lower the risk of gestational diabetes, unhealthy weight gain, and small-for-gestational-age babies. The study analyzed over 5 million pregnant women and found a significant reduction in these health risks.
A study found that gestational iron deficiency may contribute to cognitive impairments like autism, ADHD, and learning disabilities. Researchers identified a specific embryonic neuronal progenitor cell target for GID, which disrupts interneuron development.
A new study found that babies exposed to preeclampsia and gestational diabetes in the womb were biologically younger than their chronologic age. The researchers used DNA samples from over 1,800 newborns to evaluate each infant's epigenetic age and compared it to their chronological age at birth.
A new study found that pregnant individuals who give birth to large-for-gestational-age (LGA) babies are at a higher risk of developing prediabetes or Type 2 diabetes 10-14 years after childbirth. Researchers analyzed data from the Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study, which revealed a significant association bet...
A new WVU study found nearly one in eight West Virginia infants had in utero exposure to opioids, stimulants, and/or cannabis between 2020 and 2022. The study showed a 40% increased risk of preterm birth among infants exposed to stimulants alone and a 70% increase with concurrent stimulant and cannabis exposures.
Women who experience five major pregnancy complications face an increased risk of ischemic heart disease up to 46 years after delivery. The study found that all major adverse pregnancy outcomes should be recognized as lifelong risk factors for heart disease.
A new study reveals that US pregnancies are shorter than those in England and the Netherlands, with average lengths declining by over half a week between 1990 and 2020. This finding suggests that reducing medical interventions during the birthing process could improve maternity care outcomes in the US.
Researchers found that buprenorphine use was associated with better outcomes for the baby, including lower risk of preterm birth, small size for gestational age, and low birth weight. The study suggests increasing access to buprenorphine treatment among pregnant individuals with opioid-use disorder.
A Norwegian study of over 72,000 births found no increased risks of adverse outcomes for babies conceived within three months of a miscarriage or abortion. In fact, shorter intervals were associated with lower risks of small for gestational age and large for gestational age, as well as lower risk of gestational diabetes.
A large Nordic study found that children born to mothers with preeclampsia have higher risk of ischemic heart disease and stroke. The association holds even after accounting for other birth complications such as preterm birth and low birth weight.
A Rutgers study found that infants who died unexpectedly in the first week of life had different risk factors compared to those who died later. The study analyzed data from 2000 to 2015 and found that mothers of infants dying in the first week showed less evidence of common risk factors such as smoking during pregnancy.
A new study found that babies born below the 25th percentile for birthweight are at a higher risk of developmental concerns compared to those born in the middle range. The researchers suggest that better birthweight surveillance and support during childhood may help reduce these risks.
COVID-19 vaccination during pregnancy was found to lower the risk of severe outcomes including preterm birth and postpartum hemorrhage. Vaccination during pregnancy is now recommended to protect against COVID-19 infection.
A prospective multicenter case-control study found that third-trimester fetuses exposed to opioids in utero exhibited smaller brain biometric measurements and altered fetal physiology. The study suggests a possible link between prenatal opioid exposure and postnatal clinical outcomes.