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Study sheds light on the origin of the genetic code

A recent study revises our understanding of the universal genetic code's evolution, suggesting that early life preferred smaller amino acids over larger ones. The researchers found that amino acids with aromatic ring structures were incorporated into the code later than previously thought, offering clues about other extinct genetic codes.

SourceUniversity of Arizona·JournalProceedings of the National Academy of Sciences·TypeData/statistical analysis·DateDec 12, 2024

The first mouse strain that is susceptible to severe COVID-19 without genetic modification has been identified

Scientists at The Jackson Laboratory have identified the CAST/EiJ mouse as a highly susceptible model for studying severe COVID-19. This genetically pure background allows researchers to investigate the virus's impact without artificial receptor modifications, mirroring human responses. Initial trials using antiviral treatments show pr...

SourceJackson Laboratory·JournalScientific Reports·TypeExperimental study·DateDec 6, 2024

New study reveals genetic drivers of early onset type 2 diabetes in South Asians

A new study from Queen Mary University of London has identified the genetic drivers of early onset type 2 diabetes in South Asians, revealing a strong link to lower insulin production and unfavorable body fat distribution. The research also sheds light on treatment responses, highlighting the need for precision medicine approaches.

SourceQueen Mary University of London·JournalNature Medicine·TypeObservational study·DateNov 26, 2024

Bringing genomics into public policy requires greater awareness, professional training, and investment

The WHO's Technical Advisory Group on Genomics published an article outlining challenges and actions to promote the use of genomics in public health. The group aims to increase awareness and provide technical guidance to accelerate access to genetic technologies, enabling preventive measures and targeted treatment for various diseases.

Viking colonizers of Iceland and nearby Faroe Islands had very different origins, study finds

A recent study found that Viking colonizers of the Faroe Islands and Iceland came from different Scandinavian populations. The researchers analyzed genetic samples from 139 men and compared them to samples from Norway, Sweden, Denmark, Iceland, and Ireland, revealing a 'founder effect' that persists in today's male populations.

SourceFrontiers·JournalFrontiers in Genetics·TypeExperimental study·DateNov 25, 2024

Genomic databases need more diversity

Researchers at the University of Maryland School of Medicine have created a large genomic database of Latin Americans to tackle health disparities. The Genetics of Latin American Diversity Database (GLADdb) includes genome-wide information from almost 54,000 individuals and allows other scientists to easily add population data to their...

SourceUniversity of Maryland School of Medicine·JournalCell Genomics·TypeData/statistical analysis·DateOct 31, 2024

'Black box' of stem cell transplants opened in world-first blood study

Researchers tracked the long-term dynamics of transplanted stem cells in patients' bodies up to three decades post-transplant. They found that younger donors produce more vital stem cells, while older donors experience reduced immunity and higher relapse risk. The study provides new insights into donor selection and transplant success.

SourceWellcome Trust Sanger Institute·JournalNature·TypeObservational study·DateOct 30, 2024

A visit from the stork brings genomic hope for this endangered species

A new genomic study reveals high genetic diversity and low inbreeding in the endangered Oriental Stork population, a common finding in many critically endangered species. The study provides hope for the species' long-term survival and suggests that protecting its habitats could rapidly rescue this species from extinction.

SourceGigaScience·JournalGigaScience·TypeExperimental study·DateOct 21, 2024

Unlocking the genetic mysteries of modern roses

Researchers have decoded the genetic makeup of 'Samantha' rose variety to create a powerful resource for future comparative genomic studies. The study found that human selection has significantly influenced the genetic diversity of modern roses, but preserving genetic traits is essential for their health and adaptability.

SourceBoyce Thompson Institute·JournalNature Plants·TypeExperimental study·DateOct 14, 2024

Study probes how eating less can extend lifespan

A recent study by The Jackson Laboratory reveals that reducing calorie intake can significantly extend the lifespan of mice, with the most robust animals living the longest. However, the researchers found that losing weight on these diets had a negative impact on lifespan in humans.

SourceJackson Laboratory·JournalNature·TypeExperimental study·DateOct 9, 2024

Return of the elephants seals: From a few to thousands

Northern elephant seals nearly went extinct due to overhunting but have since recovered to around 225,000 individuals. The recent study found the species' genetic diversity was reduced during this period, which may impair their ability to cope with future environmental changes.

SourceBielefeld University·JournalNature Ecology & Evolution·TypeData/statistical analysis·DateSep 27, 2024

How a butterfly invasion minimizes genetic diversity

A Europe-wide invasion of the southern small white butterfly has led to a significant loss of genetic diversity within the species. The insect's expansion into new areas is facilitated by urbanization and its preference for human-designed habitats, but this comes at the cost of reduced genetic variation.

SourceUniversity of Basel·JournalCurrent Biology·DateSep 24, 2024

Most new recessive developmental disorder diagnoses lie within known genes

A recent study by the Wellcome Sanger Institute and GeneDx analyzed nearly 30,000 families with developmental disorders, revealing that known genes explain over 80% of cases caused by recessive genetic variants. The team identified several new genes associated with these conditions, providing answers for previously undiagnosed families...

SourceWellcome Trust Sanger Institute·JournalNature Genetics·TypeObservational study·DateSep 23, 2024

Can captive tigers be part of the effort to save wild populations?

A new study from Stanford University provides a tool for conservationists and law enforcement to protect captive tigers and prosecute wildlife crimes. The researchers analyzed the genetic diversity of privately held tigers in the US, finding that many are a mix of wild tiger ancestry, but also reflect characteristics of the illegal trade.

SourceStanford University·JournalProceedings of the National Academy of Sciences·DateSep 19, 2024

Sweet success: genomic insights into the wax apple's flavor and fertility

A recent study has successfully decoded the autotetraploid genome of the wax apple, uncovering its genetic evolution and key factors driving fruit diversity. The research highlights the fruit's rich antioxidant profile, with implications for human health, and identifies genes regulating fruit size, sugar content, and male sterility.

Ancient DNA from Rapa Nui (Easter Island) refutes best-selling population collapse theory

A new study challenges the long-held 'ecocide' theory of Rapanui population collapse by analyzing ancient DNA from 15 individuals. The research found no evidence of a dramatic population collapse in the 1600s, instead revealing a stable and growing population until European contact in the 18th century.

SourceUniversity of Copenhagen - The Faculty of Health and Medical Sciences·JournalNature·TypeComputational simulation/modeling·DateSep 11, 2024