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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Neuronal basis of duet singing in plain-tailed wrens

Researchers found that HVC neurons increase activity during solo syllable production and decrease when the partner sings, suggesting inhibition of motor circuits. This neural mechanism enables rapid turn-taking in duet singing, where males and females rapidly take turns singing at a rate of 2 to 5 Hz.

Same nerve cell -- Different influence on food intake

Researchers have identified two subtypes of POMC neurons with distinct hormone sensing and appetite suppression profiles. The findings suggest that the diversity of these neurons is crucial for their function in regulating metabolism.

Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

Reaching your life goals as a single-celled organism

Researchers at TU Wien simulate single-celled organism movement using artificial intelligence and a physical model, revealing how it achieves chemotaxis despite lacking a nervous system. The virtual organism learns to direct its movement through a simple control network, similar to biological evolution.

Researchers trace spinal neuron family tree

Salk researchers have traced the development of spinal cord neurons using genetic signatures, revealing new ways of classifying and tagging subsets of cells. The findings offer a precise way to study the function of spinal cord neurons and their role in regulating body movements.

A neuromagnetic view through the skull

A team of researchers has successfully developed a highly sensitive magnetoencephalography (MEG) technology that can detect even fast brain oscillations produced in response to single sensory stimuli. This breakthrough enables noninvasive observation of nerve cells transmitting information, shedding light on factors such as alertness a...

Decoding smell

Scientists have discovered that the brain perceives odor mixtures as a new identity, rather than a combination of individual odors. This finding supports the pattern theory of sensory encoding, which suggests that multiple neurons are activated simultaneously to create a population code for each smell.

Sony Alpha a7 IV (Body Only)

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Scientists solve long-standing mystery by a whisker

Researchers at UC Riverside identified a cortical region in mice that transforms sensory input into movement, opening new directions for studying sensory-motor transformations. The discovery could lead to targeted therapy for patients with sensory- and motor-related brain deficits.

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Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

New technique to fast-track pain research

Researchers at Flinders University have developed a new technique to replicate sensory neurons involved in pain sensation, providing ample resources for testing potential drugs. The technique allows for the easy generation of large numbers of cells, enabling the simultaneous testing of thousands of samples or potential drug libraries.

Balancing brain cell activity

Brain cells produce brief electrical impulses triggered from highly specialized regions that adapt to sensory experiences. The study found that these trigger sites shrink with increased experiences and grow larger with reduced input.

GridTape: An automated electron microscopy platform

The new technique allows researchers to study whole neural circuits in high detail and at scale. They used it to create a comprehensive map of neuronal circuits that control motor function in fruit flies, discovering new sensory neurons.

Researchers identify neurons that control nausea-like responses in mice

A new study has identified and characterized neurons that regulate nausea-like responses in mice, shedding light on the sensation of nausea. The findings reveal a division of labor between area postrema neurons, with different neuron types responsible for detecting and raising the alarm for various substances.

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When it comes to feeling pain, touch or an itch, location matters

Researchers at the Salk Institute have mapped the physical organization of cells in the spinal cord that help mediate critical sensorimotor reflexes. The study found that different neurons in the same space had the same function, while more similar neurons located in different areas were responsible for different reflexes.

New fundamental knowledge of the 'abdominal brain'

The study describes how the different neurons form during fetal development, a process that follows different principles to brain neurons. The researchers identified twelve different kinds of ENS neuron, including subgroups of sensory neurons activated by substances in the intestines and affecting the immune system.

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Printable ink guides cell growth, offers nerve injury hope

A team of researchers from Australia, India, and Bangladesh have developed a neuron-growing ink that uses the body's own electrical signals to guide the growth of nerve cells. The bioconductive ink can be printed in lines to direct where neurons grow, cracking a major challenge in nerve engineering.

The line of succession

A specific region of messenger RNAs plays a crucial role in brain cell function. The study reveals an unusual EXAR (EXon-Activated Rescue) mechanism that secures this process, using ELAV and FNE proteins to determine neuronal transcript signatures.

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Scientists identify sensor protein that underlies bladder control

Researchers at Scripps Research have identified the PIEZO2 protein as a crucial part of how our body detects bladder fullness. The discovery sheds light on the mechanism underlying normal bladder function and may lead to new treatments for bladder control and urination issues, particularly among the elderly.

Scientists discover mosquitoes' unique blood-taste detectors

Researchers found a group of neurons in female mosquitoes' stylets that activate only when sugar, salt, and other components of blood are present together. This discovery opens the door to further examination of novel forms of taste detection and unique feeding strategies.

UMD biologist awarded $ 1.5 million to develop brain mapping techniques

A University of Maryland biologist has been awarded $1.5 million to develop new tools for studying brain mapping techniques. The project aims to create a comprehensive molecular map of synapses during development, aging, and disease, which could lead to potential treatments for neuropsychiatric disorders and other cognitive functions.

Apple Watch Series 11 (GPS, 46mm)

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Study finds odor-sensing neuron regeneration process is adaptive

Researchers found that reduced odor stimulation reduces newly-generated neurons with specific receptors, suggesting a selective alteration in neurogenesis. This discovery challenges the random subtype identity model and suggests a potential adaptive function for lifelong olfactory sensory neurogenesis.

Nose's response to odors more than just a simple sum of parts

Research from Kyushu University shows that odors can activate or suppress the response of olfactory sensory neurons in mice, leading to complex interactions and synergy when mixing odors. This study provides new insights into how our perception of odors is tuned from the moment they are detected in the nose.

Reprogramming brain cells enables flexible decision-making

Researchers at the University of Zurich have discovered that the orbitofrontal cortex can reprogram neurons in sensory areas to enable flexible decision-making. This process involves a direct connection between the two regions, allowing for rapid adaptation to new situations.

Immune cells sculpt circuits in the brain

Researchers found that microglia direct neurons to modify their connectivity in response to visual stimuli, shaping the brain's neural circuits. This discovery sheds light on how sensory experience influences brain maturation and may have implications for neurodevelopmental disorders such as autism.

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Rubbing skin activates itch-relief neural pathway

A recent study published in JNeurosci found that stroking skin triggers an anti-itch neural pathway in the spinal cord, reducing itchiness. The researchers discovered that sensory neurons under the skin activate anti-itch interneurons, leading to reduced neural activity and relief from itching.

Paying attention to the neurons behind our alertness

Researchers used two-photon imaging to study the activity of layer 6 neurons in mice, finding three distinct populations that reacted differently to visual stimulation. These neurons complement each other to regulate information flow from sensory organs to the cortex, influencing our ability to focus or lose attention.

Two distinct circuits drive inhibition in the sensory thalamus of the brain

Research identifies two functionally distinct sub-circuits in the sensory thalamus that process distinct classes of information. These circuits enable powerful new optogenetic and chemogenetic strategies to probe behavioral and perceptual functions, potentially shedding light on conscious awareness and epilepsy.

Revealing how flies make decisions on the fly to survive

Researchers studied how hoverflies process visual information to control their flight movements, finding that descending neurons adapt like sensory neurons but also persistently fire like motor neurons. This unique integration of responses offers insights into the brain-behavior link in flies and potentially all vertebrates.

AmScope B120C-5M Compound Microscope

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Neural circuits mapped: Now we understand vision better

A study by Aarhus University researchers has discovered the function of nerve cells in the eye that sense visual movement. This knowledge is crucial for developing targeted treatments for diseases like dementia and schizophrenia.

Common protein in skin can 'turn on' allergic itch

A study from North Carolina State University found that the protein periostin can directly activate itch-associated neurons in the skin, leading to increased itching in atopic dermatitis. Blocking periostin receptors reduced itch response in a mouse model of eczema.

Gut communicates with the entire brain through cross-talking neurons

A recent study published in Autonomic Neuroscience: Basic and Clinical reveals the extent of connections between the small intestine and the entire brain. Half of the neurons transmitting signals from the gut to the brain also send motor signals, enabling cross-talk within the same neuron.

The neural basis of sensory hypersensitivity

A new study reveals a neural circuit that underlies sensory hypersensitivity in mice with autism-like traits. The research suggests that reestablishing normal levels of neuron activity could reverse this kind of hypersensitivity, providing a potential target for developing treatments.

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New knowledge on how different brain cell types contribute to our movements

Researchers at Karolinska Institutet have discovered how different brain cell types in the striatum respond to sensory inputs and motor commands, shedding new light on how we align our movements with sensory feedback. The study reveals distinct receptor compositions and response patterns among five striatal neuron populations.

Decoding hidden brain chatter to advance neuroprostheses

Researchers have discovered a way to reconstruct stable neural activity patterns from tens of neurons, potentially allowing for consistent control of neuroprostheses over long periods. This breakthrough has immediate implications for advancing neuroprosthetic devices that bypass neurological injuries.

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

A surprising new source of attention in the brain

Research at Rockefeller University discovered a new brain area, PITd, that steers attention and challenges the long-held concept of attention control. The finding suggests a rethinking of old concepts about attentional control and highlights the complexity of the brain's attention mechanisms.

Scientists unpack how taste neurons control food intake

A UC Riverside-led research team found that fruit fly taste neurons can detect different categories of aversive chemicals and convey this information to the brain, where it controls food intake. The study's findings have implications for understanding feeding behavior in insects and could lead to strategies for controlling insect pests...

Startled fish escape using several distinct neuronal circuits

Researchers identified a cluster of 38 neurons in the hindbrain that mediate delayed escape responses in zebrafish, characterized by flexible trajectories. This circuit may represent an evolutionarily ancient pathway for defensive responses to threats sensed via acoustic or vibrational cues.

GQ GMC-500Plus Geiger Counter

GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

Atopic dermatitis: How allergens get on our nerves

Researchers have identified a key mechanism underlying atopic dermatitis, a chronic inflammatory skin disease affecting 20% of children and 5% of adults. The study reveals that mast cells and sensory neurons interact in 'sensory neuroimmune units' to detect allergens, triggering inflammation.

Autism-related behaviors are shaped by neurons outside of the brain

Research shows that neurons outside the brain play a crucial role in autism spectrum disorders, particularly in touch perception and social behavior. Peripheral somatosensory neurons are key players in this process, suggesting a potential new approach to treating ASD-related symptoms.

Is this brain cell your 'mind's eye'?

Researchers suggest a structural connection between 'content circuits' in the cortex and 'switchboard circuits' that allocate awareness, mediated by L5p neurons. Studies demonstrate interaction between state and contents of consciousness in these cells.

CalDigit TS4 Thunderbolt 4 Dock

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Body representation in monkeys' brains

Researchers investigate the neuropsychological basis of body representation in monkeys using a combination of illusions and behavioral tasks. The study reveals how the brain establishes a sense of body ownership, with activity in the premotor cortex correlating with perceived arm position.

Garmin GPSMAP 67i with inReach

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Defective potassium channels cause headache, not body pain

Research in mice suggests that defective potassium channels involved in pain detection can cause headaches and may be a target for future migraine treatments. The study found that the channels, specifically TRESK, regulate pain in facial sensory neurons, making them a promising area of focus for headache research.

Neurons that fire alike are connected in the olfactory map

Scientists report that specific patterns of neural activity guide the formation of nerve clusters in the olfactory bulb, enabling variation in response to sensory cues. By changing neural activity patterns using optogenetics, researchers found altered expression of molecules in nerve endings targeting specific nerve clusters.