Articles tagged with Glucose
A new study from Kaiser Permanente found that pregnant women with gestational diabetes who achieve rapid glucose control have better birth outcomes. The research analyzed data from over 26,000 patients and identified four trajectories of glucose control, with those starting out with optimal levels and maintaining it having the best res...
A research team has identified the transporters responsible for sugar uptake in Clostridium thermocellum, a key industrial microorganism. The study found that transporter B is used to take up cellodextrins derived from cellulose, while transporter A is used for glucose uptake.
Researchers developed a novel 3D microfluidic device to study complicated processes within the placenta, including placental malaria. The model demonstrates that CSA-binding infected erythrocytes add resistance to the simulated placental barrier for glucose perfusion and decrease glucose transfer across this barrier.
Repeated cold-induced shivering improves glucose tolerance, decreases fasting blood sugar, and reduces blood fat levels in overweight adults. It also markedly lowers blood pressure and has a beneficial effect on triglycerides and free-fatty acids.
Researchers found that nerve damage in the cornea increases with glucose metabolism impairment and blood sugar levels, suggesting early detection may delay or prevent complications. The study suggests high blood sugar levels can begin to damage corneal nerves long before type 2 diabetes develops.
Research at Karolinska Institutet shows that people with diabetes have lower levels of psoriasin, a key peptide that weakens the bladder's protective barrier function. This increases the risk of urinary tract infections. Oestrogen therapy may help regulate the immune response to UTIs in patients with diabetes.
Researchers at Nagoya University have discovered a new treatment for type 1 diabetes that uses leptin to improve insulin-alternative effects in mice. The combination of leptin and a PTP1B inhibitor normalizes blood glucose levels without the need for insulin, reducing hypoglycemia risk.
Researchers found that bird neurons consume three times less glucose than mammalian neurons, allowing for high cognitive abilities and complex brain structures. This discovery sheds light on the evolutionary advantages of birds' brains.
Researchers have combined tesaglitazar and GLP-1 in a new hormone combination for type 2 diabetes treatment, improving glucose metabolism with minimal doses. The new drug has shown promise in animal studies, reducing kidney damage and increasing insulin sensitivity.
A controlled trial found that non-nutritive sweeteners alter human gut microbiomes and glucose tolerance in a personalized manner. The effects of the sweeteners on the microbiome were closely correlated with alterations in glucose tolerance.
Researchers found that non-nutritive sweeteners can change the composition and function of gut microbes in humans, leading to altered glucose tolerance. The study suggests a personalized effect on glycemic responses due to individual variations in microbiome composition.
A new study suggests that the true figure of undiagnosed diabetes in the US is significantly lower than current government estimates, with a prevalence rate of around 9.5% of the total diabetes burden. Disparities in access to healthcare and screening contribute to higher rates in older adults, racial/ethnic minorities, and those witho...
Researchers at Washington University in St. Louis found that cancer cells metabolize glucose in their mitochondria, following conventional biochemical patterns. The study suggests that limiting glucose uptake may not be an effective strategy to target cancer cells, and glucose metabolism may need to be reevaluated as a therapeutic target.
A new study led by Marc Veldhoen found that tissue resident white blood cells use glucose as an energy source and have a faster metabolism than circulating lymphocytes. This discovery highlights the importance of having a balanced diet for a healthy immune response.
A team of researchers at Mount Sinai discovered a molecular mechanism involving carbohydrate response-element binding protein (ChREBP) that plays a key role in glucose toxicity and beta-cell death. Increasing expression of an alternate form of ChREBP or activating nuclear factor-erythroid factor 2 can preserve beta-cell mass.
A study found that cold temperatures activate brown adipose tissue that competes with tumors for glucose, inhibiting tumor growth and prolonging survival. Researchers suggest that cold therapy could be a promising approach to cancer therapy.
A new light-based sensor harnesses the light-guiding properties of spider silk to detect and measure small changes in the refractive index of a biological solution, including glucose and other types of sugar solutions. The sensor is practical, compact, biocompatible, cost-effective, and highly sensitive.
A new study from Edith Cowan University found that acupuncture therapy significantly improved fasting plasma glucose, two-hour plasma glucose, and glycated haemoglobin levels in people with prediabetes. The therapy also showed a greater decline in the incidence of prediabetes without adverse reactions.
Researchers have developed a battery-free biosensor that can track glucose levels in sweat using radio frequency signals. The device, resembling a smart necklace, showed promising results in monitoring glucose levels during exercise and has potential applications for detecting other biomarkers in bodily fluids.
Researchers found that factory-calibrated continuous glucose monitors are sufficiently accurate for estimating blood-sugar levels in patients with end-stage renal disease on hemodialysis. The devices showed 'clinical reliability', with almost 99% of readings accurate enough to be used without confirmatory fingerstick blood sugar readings.
The University of Houston research team has successfully developed a method for 3D printing organic semiconductor devices using multiphoton lithography, enabling the creation of highly conductive microstructures. The technology has potential applications in emerging fields such as nanoelectronics and bioelectronics.
Researchers have developed a novel fusion protein that enables the detection of SARS-CoV-2 antibodies using widely available glucose meters. The test was validated on various patient samples and found to be as accurate as four different ELISAs.
A new processing technique could make potatoes healthier by slowing starch digestion and reducing blood sugar spikes. The approach blocks certain digestive enzymes from reaching potato starch as quickly, leading to a more controlled release of dietary glucose.
A University of Jyväskylä study found that menopausal women's ability to use fat as an energy source is not impaired by estrogen levels or menopause. Women who burned more fat during exercise had higher fitness and physical activity levels, while those with better glucose tolerance did not necessarily burn more fat.
A high-fat diet can lead to increased fructose metabolism in the small intestine, resulting in the release of glycerate into circulation. This can cause damage to insulin-producing pancreatic beta cells, increasing the risk of glucose tolerance disorders and Type 2 diabetes mellitus.
A new study from UT Southwestern Medical Center found that telemedicine and continuous glucose monitoring helped reduce the negative impacts of COVID-19 on children with Type 1 diabetes. Despite a decrease in office visits, disease management remained unchanged, but disparities persisted among minority and low-income patients.
Research describes how breast cancer cells impair pancreatic islet function to suppress insulin production, leading to diabetes and increased tumor growth. The study identifies microRNA-122 as a key player in this process.
A small protein supplement taken before meals can help people with type 2 diabetes control their blood sugars for two extra hours a day. The study found daily glucose levels were also 0.6 mmol/L lower when taking the supplement.
Researchers at North Carolina State University discovered that female German cockroaches averse to glucose reject male offers of body secretions containing sugars and fats. The study shows that glucose-averse females sense a bitter taste when mixing their saliva with the male secretions, ending the courtship ritual.
A novel connection between genes involved in mitosis and glucose metabolism was found by researchers at Nagoya University. They demonstrated a gene bypass process using evolutionary repair experiments, suggesting that suppressing both Plk1 and CK1 could be more effective in cancer treatment.
Researchers developed a strong, water-resistant wood glue using glucose and citric acid for plywood. The adhesive meets China's standard requirement and is more energy-efficient than traditional adhesives.
A new wearable device can simultaneously monitor glucose, alcohol, and lactate levels, providing users with a comprehensive picture of their health. This technology has the potential to improve disease management for individuals with diabetes and other conditions, as well as enhance overall wellness through real-time tracking.
A new study published in Scientific Reports reveals that regular high-intensity interval training exercise can significantly decrease fasting glucose levels and waist circumference, while improving oxygen consumption rates in patients with non-alcoholic fatty liver disease. Exercise also modifies amino acid metabolism in adipose tissue...
Researchers found that grandmaternal exercise improved glucose tolerance and decreased fat mass in adult male and female grand offspring. The study suggests that exercise during pregnancy may have long-lasting effects on metabolic health, potentially reducing the worldwide incidence of obesity and type 2 diabetes.
A recent study published in PLOS Medicine found that having a parent with type 1 diabetes may be linked to lower school performance in children. The research involved over 622,000 Danish children and suggested a negative association between parental type 1 diabetes and cognitive development.
A recent study analyzed data from 421 adults with type 2 diabetes and found that achieving optimal blood pressure, glucose, cholesterol, and body weight levels can significantly improve life expectancy. By targeting these key health metrics, individuals with type 2 diabetes may be able to extend their lifespan.
Researchers have developed RNA molecules that selectively target human pancreatic beta cells, allowing for the delivery of therapies directly to these cells. This breakthrough enables the study of diabetes progression and provides new opportunities for precision treatments.
A study suggests that the powerhouse-pruning protein Drp1 plays a crucial role in generating energy for new blood vessel growth, particularly under low oxygen conditions. When oxygen levels are low, Drp1 gets modified to produce reactive oxygen species (ROS), which enables glycolysis and subsequent cell signaling.
Researchers developed a compound consisting of insulin bound to an antioxidant group, improving glucose consumption and brain function in mice with type 1 diabetes. The combination therapy showed better cognitive performance than individual treatments alone.
Mayo Clinic researchers propose a novel computational model that links Alzheimer's disease symptoms to brain anatomy, revealing a complex relationship between mental processing and brain function. The model uses machine learning to analyze patient brain imaging data and compresses complex brain anatomy into a conceptual framework.
A research team found that limiting energy in neurons increases hyperexcitability and severity of seizures in mice. The ketogenic diet restored mitochondrial function and reduced seizure intensity.
Researchers have identified two glucose transporters that disrupt the energy supply to invading worm cells and stop them in their tracks. By deactivating these genes, glucose and ATP levels dropped, and worm cells stalled their spread. This discovery could lead to new ways to cut off cancer cells' fuel lines and prevent metastasis.
Researchers identified peripheral tissues as source of blood amyloid beta, which regulates blood glucose levels and suppresses insulin secretion. The study suggests a possible mechanism linking type 2 diabetes to Alzheimer's disease development.
Researchers found that chronic lactate exposure can lead to cellular disruptions, decreased fatty acid transport, and alterations of mitochondrial membranes, which may contribute to the development of heart failure and type 2 diabetes. The study suggests that lactate accumulation could be a major player in disease progression.
Scientists have created a 'greener' way to clean wastewater treatment filters by using glucose-based nanoparticles, which effectively remove contaminants without destroying the membrane. The new system is more cost-effective and environmentally friendly than traditional methods.
Researchers found that bilobalide, an active ingredient in Ginkgo biloba extract, protects the heart from ischemic injuries by preserving ATP generation and enhancing metabolic flux. The study suggests that bilobalide may provide a new herbal therapy for treating myocardial ischemia.
Researchers at TUM have successfully produced succinic acid using the marine bacterium Vibrio natriegens, which has rapid growth and substrate uptake rates. The team is now working to optimize the process for industrial-scale production using renewable raw materials.
A retrospective cohort study of patients with atrial fibrillation and diabetes found that non-vitamin K antagonist oral anticoagulants (NOAC) were associated with a lower risk of diabetes complications and mortality than warfarin. The study suggests that NOAC may be a better therapeutic choice for this patient population.
Researchers at Lancaster University have identified a genetic change that impacts insulin signaling and glucose metabolism in the brain, which may lead to effective drug treatments for autism. The study found that individuals with a specific DNA deletion are more likely to develop neurodevelopmental disorders, including autism.
Researchers at the University of Bath have developed a novel chemical glucose sensing method based on boronic acids and graphene foam. The new technique can accurately detect lower glucose concentrations than current systems, making it ideal for chronic conditions like diabetes.
Researchers at MIT have developed an all-in-one approach to diabetes treatment, streamlining the process of blood glucose measurement and insulin injection. The new device can automate procedures such as pricking skin, collecting blood, calculating glucose levels, and dispensing insulin, reducing the need for multiple devices and makin...
A new artificial pancreas system has been shown to be safe and effective in managing blood sugar levels in very young children with type 1 diabetes. The hybrid closed-loop system, CamAPS FX, reduced average blood sugar levels and improved glucose control without increasing the risk of hypoglycemia.
A new wearable sensor has been developed using MXene nanomaterials that can detect changes in pH levels in sweat, which correlate with muscle fatigue. The device measures electrical resistance patterns in response to mechanical stress and pH changes.
A cross-sectional study found that mild autonomous cortisol secretion (MACS) predominantly affects women, increasing the frequency and severity of hypertension and type 2 diabetes compared to nonfunctioning adrenal tumors. Patients with MACS carried an increased cardiometabolic burden similar to Cushing Syndrome, even without typical f...
Researchers at RIKEN have developed a healthier form of tapioca starch by suppressing multiple genes that increase its resistance to digestion. The resulting starch is composed of longer chains with fewer branches, making it harder to digest and potentially improving intestinal function and blood sugar control.
A study in mice suggests that transplanted brown fat can reduce type 2 diabetes risk factors after a heart attack by dampening gene activation linked to negative effects. The transplantation method could help researchers understand the mechanisms behind this protective effect and potentially lead to therapeutic applications.
Researchers developed an AI-powered system to model disease progression in patients as they age. The model assesses metabolic and cardiovascular biomarkers to calculate health status and disease risks across a patient's lifespan.
A University of Gothenburg study found that bariatric surgery lowers cancer risk by 60% in obese patients with type 2 diabetes, particularly those achieving and maintaining normal glucose control. The research highlights the importance of glucose control in preventing cancer in this high-risk population.
A team of researchers at UC Davis Health has developed a novel PET imaging-based tool to detect liver inflammation in non-alcoholic fatty liver disease. The tool uses dynamic PET imaging and mathematical modeling to measure glucose transport from blood to liver tissue, allowing clinicians to quantify liver inflammation.
Researchers genetically engineer E. coli microbes to convert glucose into olefins, a type of hydrocarbon found in gasoline, using a two-step process with a catalyst. This method has potential to advance green energy technology and create sustainable biofuels.