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Science News Archive July 2021 - Page 16


Page 16 of 41

Spinal fluid biomarkers detect neurodegeneration, Alzheimer's disease in living patients

Researchers at the University of Pennsylvania School of Medicine have developed a framework to detect Alzheimer's disease and other forms of neurodegeneration using cerebrospinal fluid biomarkers. The ATN framework, which includes three biomarkers, has been shown to provide accurate diagnoses for patients with frontotemporal degeneration.

COVID-19 shutdowns reveal racial disparities in exposure to air pollution

A new study by George Washington University researchers reveals that even during COVID-19 shutdowns, marginalized neighborhoods experienced higher levels of health-harming nitrogen dioxide compared to wealthier communities. Nitrogen dioxide emissions from traffic were found to persist in these areas despite reduced passenger vehicle tr...

SourceGeorge Washington University·JournalProceedings of the National Academy of Sciences·DateJul 20, 2021

Medical debt in US

A study analyzed credit reports to estimate national and regional medical debt burdens, revealing a significant increase. The analysis found that Medicaid expansion under the Affordable Care Act reduced medical debt burdens, particularly among low-income individuals.

SourceJAMA Network·JournalJAMA·DateJul 20, 2021

SARS-CoV-2: Achilles' heel of viral RNA

Scientists at Goethe University have identified 15 short segments of the SARS-CoV-2 genome that are highly conserved across various coronaviruses and perform essential regulatory functions. These segments were found to be resistant to mutations, making them promising targets for developing new drugs against SARS-CoV-2.

SourceGoethe University Frankfurt·JournalAngewandte Chemie International Edition·DateJul 20, 2021

COVID-19 news from Annals of Internal Medicine

Researchers found that COVID-19 vaccines are more than 95% effective in preventing confirmed infection. The study also revealed significant disparities among different age groups and comorbidities, with higher risks observed among older adults and those with underlying health conditions. Additionally, a separate cohort study showed tha...

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·DateJul 20, 2021

Using snakes to monitor Fukushima radiation

A University of Georgia study finds that rat snakes can effectively monitor residual radioactivity in the Fukushima Exclusion Zone. The snakes' limited movement and close contact with contaminated soil allow them to accumulate high levels of radionuclides, making them a useful bioindicator.

SourceUniversity of Georgia·JournalIchthyology & Herpetology·DateJul 20, 2021

Revealing the secrets of cell competition

Research found that cells with defective mitochondria and sequence changes in their genome are 'loser' cells in mouse embryos, suggesting that mitochondrial dysfunction is a common characteristic of competing cells. The study suggests that mitochondrial activity may be a key determinant of cellular fitness in various biological contexts.

Research shows employer-based weight management program with access to anti-obesity medications results in greater weight loss

A study by Cleveland Clinic found that combining a weight management program with FDA-approved anti-obesity medications leads to significant weight loss among adults with obesity. The research showed that participants who had access to the medications averaged -7.7% weight loss at 12 months, compared to -4.2% in those without medication.

SourceCleveland Clinic·JournalJAMA Network Open·DateJul 20, 2021

Strong signals

A team of scientists at the University of Tsukuba created a computer simulation that models the Delta-Notch signaling pathway in biliary cell differentiation. The study reveals the importance of fine-grained differentiation and proper development, dependent on the rates of production of Delta ligands and Notch receptors.

SourceUniversity of Tsukuba·JournalBMC Research Notes·DateJul 20, 2021

More than 1.5M children lost a primary or secondary caregiver due to the COVID-19 pandemic

A study published in The Lancet estimates that over 1.5 million children worldwide have lost a parent, custodial grandparent, or other older relative due to COVID-19-related deaths. This phenomenon, known as orphanhood, has severe and long-lasting consequences for children's mental health and wellbeing. To address this issue, evidence-...

Preparing for the next pandemic: Harmonize vaccinations in Canada

A proposed Canadian Immunization Services model could provide a coordinated approach to vaccination across the country, addressing fragmentation in data sharing, vaccine procurement, and supply chain management. The independent not-for-profit corporation would be funded by provinces, territories, and potentially the federal government.

SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·DateJul 19, 2021

Coffee and heart beats

A study by Gregory M. Marcus and colleagues found that daily coffee consumption may increase the risk of cardiac arrhythmias. The researchers analyzed data from a large population, suggesting that moderate coffee drinking may be associated with an increased risk of irregular heartbeats.

SourceJAMA Network·JournalJAMA Internal Medicine·DateJul 19, 2021

To die or not to die in response to stress, a decision regulated by MK2 protein levels

The study reveals that MK2 protein levels act as a molecular indicator for cell survival or death, with higher levels associated with cell death and lower levels linked to survival. Moderate stress triggers temporary activation of the p38-MK2 pathway, allowing cells to recover.

SourceInstitute for Research in Biomedicine (IRB Barcelona)·JournalProceedings of the National Academy of Sciences·DateJul 19, 2021

No stone unturned: An extensive search for cation substitution in lithium-ion batteries

Researchers at Japan Advanced Institute of Science and Technology developed a novel method to predict the optimal cation substitutions in lithium-ion batteries using first-principles calculations. The study reveals that nickel can be partially substituted with platinum and palladium to increase battery discharge capacity, while other e...

SourceJapan Advanced Institute of Science and Technology·JournalThe Journal of Physical Chemistry C·DateJul 19, 2021