Researchers report a novel intersection among quantum optics, atomic physics, and precision metrology with the achievement of sub-shot-noise optical readout in a Rydberg atomic medium. The study utilizes velocity-selective Rydberg EIT to enable low-loss optical interface and coherent propagation of squeezed light.
Researchers create ultra-coherent and efficient photonic integrated circuits by extending optical fiber's ultralow loss performance to silicon wafers. This breakthrough paves the way for precision measurements, AI data-center communications, and quantum computing applications.
Researchers introduce a new strategy using natural wood as a structural scaffold for conductive eutectogels, enabling mechanically robust and environmentally stable materials. The resulting eutectogel achieves high tensile strength, toughness, and ionic conductivity, making it suitable for wearable electronics and smart sensing systems.
Researchers have developed a hybrid-phase cooperative dispersion-engineering strategy to unlock independent, dual-spin achromatic wavefront control in a single-layer metasurface. This breakthrough enables truly independent dual-spin control of phase and group delay within a compact platform.
A compact sensor achieves multispecies gas detection with high selectivity and sensitivity, utilizing nanomaterial-functionalized fibers and Kerr soliton dual-microcombs. The system successfully identified 12 distinct components in complex gas mixtures, achieving record-low detection limits.
Researchers used CRISPR/Cas9 to introduce a popcorn-like fragrance to tomatoes by disrupting the BADH2 gene. The resulting aroma enhances sensory appeal and flavor quality without affecting plant growth or agronomic traits.
Researchers developed a highly accurate computer model to simulate the entire tunnel excavation process, comparing ground anchors and pre-support pipes. The study found that a combined lining and anchor system is sufficient to control rock stress and deformation in deep mountain tunnels.
Physicists have developed a new terahertz microscope that allows them to observe quantum vibrations in superconducting materials for the first time. The microscope enables researchers to study properties that could lead to room-temperature superconductors and identify materials that emit and receive terahertz radiation.
Researchers from CAMH and RWTH Aachen deciphered the molecular signature of sleeping nociceptors, a type of pain-sensing nerve cell that drives chronic pain. The findings reveal specific molecular hallmarks, including OSMR and Nav1.9, which could lead to the development of targeted therapies.
New research suggests that parts of ancient Earth formed continents and recycled crust through subduction over 4 billion years ago. The study of zircons found in Western Australia challenges models that considered early Earth as a stagnant, unmoving 'lid' with no continental crust.
A new AI-powered analysis tool called PROVIZ is being tested in Norwegian hospitals to diagnose prostate cancer. The tool helps doctors determine which patients need a biopsy, reducing the number of unnecessary procedures.
A high-radiation-tolerance GaN detector was fabricated to enable real-time two-dimensional position detection of individual alpha particles and xenon heavy ions. The detector exhibited stable operation at radiation levels significantly higher than those tolerated by conventional Si-based detectors.
Programs promoting equity, diversity, and inclusion initiatives in healthcare institutions are associated with an increased workforce. These programs support a more inclusive and equitable health care culture, according to the systematic review and meta-analysis.
A new synthesis challenges the dominant handicap principle theory, arguing that honesty evolves when it's beneficial and deception is costly. The Signalling Trade-Off Theory suggests that trade-offs between investments and benefits define whether deception or honesty emerges.
OpenScholar, an open-source AI model, was designed to synthesize current scientific research and cite sources accurately. The model outperformed other state-of-the-art models in accuracy, writing quality, and relevance.
A team of researchers has discovered an oral compound that selectively induces the mammalian clock gene Per1, promoting a dual E-box DNA element's activation. This results in the advancement of both central and peripheral clocks, advancing jet lag and shift work-related sleep disorders.
Engineered yeast cells can mimic real cancer cells and be used to test new cancer immunotherapies much faster and cheaper than before. This new technology enables researchers to assess which CAR T variants are most promising much more quickly, leading to safer and more targeted cancer treatments.
Researchers at the Netherlands Cancer Institute developed a deep learning model PARM that predicts gene regulation with unprecedented accuracy. The model enables the prediction of functional impact of regulatory mutations in specific cell types, opening new paths for cancer diagnostics and patient stratification.
A new study found semaglutide to be an effective treatment for preventing secondary cardiovascular disease in US adults. The medication meets conventional thresholds when used alone, but its cost-effectiveness is improved with combination therapy.
Chronic cellular stress drives liver cell cancer growth, suppressing immune response. Activated ATF6α makes tumors responsive to immunotherapy, opening up new therapeutic approaches.
A new study identifies the somato-cognitive action network (SCAN) as responsible for Parkinson's disease symptoms, which can be treated with non-invasive transcranial magnetic stimulation. Targeting this network improves symptoms more than twice as much as treatments targeting nearby brain areas.
Researchers have created a new comparative model that accelerates muscle loss in zebrafish, allowing for the study of sarcopenia and potential therapies. The 'atrofish' model reveals early structural vulnerabilities in aging muscle and a surprising link between muscle loss and nerve degeneration.
A ketogenic diet was found to have a modest effect in reducing depressive symptoms in patients with treatment-resistant depression. The study's results suggest that this dietary approach may be worth exploring as an adjunct therapy option.
Researchers discovered a single protein, Rip1, that recognizes bacteriophages and causes infected bacteria to die prematurely. This protein works by forming a ring that inserts into the bacterial inner membrane, killing the cell before the infecting phage can replicate.
Dr. Stephen Fuselier, a renowned heliophysicist and member of the National Academy of Sciences, has been appointed vice president of SwRI's Space Science Division. He brings over four decades of experience in space science to lead the division.
A new study led by Dr. Jeffrey Green found that nostalgia and feelings of social connection boost gratitude levels. Engaging in nostalgic experiences can strengthen social ties, promoting a sense of gratitude for life and experience.
Researchers discovered a previously unknown stage, nicknamed the 'Crown' stage, crucial for malaria parasite reproduction. This stage helps ensure proper internal structure passage to daughter cells.
A new simulation tool, silverlinings.bio, analyzes the economic gains and social returns of advancing geroscience. The tool explores the potential of slowing age-related diseases to reduce medical costs and increase workforce longevity.
A team of researchers at Washington State University discovered that rete ridges, a microscopic skin structure shared by humans, pigs, and grizzly bears, develop shortly after birth. This finding holds potential for new therapies to reverse or slow skin aging and improve wound and scar repair.
Researchers at the University of Virginia Health System have identified a molecule that blocks the gene responsible for glioblastoma, a fast-growing and deadly brain cancer. The compound shows promise in preventing the invasive cancer from spreading through the brain without causing harm to healthy tissue.
Twenty-seven University of Michigan students and faculty scholars have been awarded Fulbright grants to conduct overseas research. Ava Kuiper, a recent graduate, teaches English and conducts research studies on chemistry education and basic science in Mexico.
The Beijing Institute of Technology Press Co., Ltd is recruiting young editorial board members who will contribute to the publication process and benefit from training and networking opportunities.
A new study reveals that CFC replacement chemicals and anaesthetics are behind a third of a million tonnes of trifluoroacetic acid (TFA) being deposited from the atmosphere across the Earth's surface between 2000 and 2022. TFA production is expected to continue growing, posing environmental concerns.
A new 'Take a Break KIDS' edition helps children manage stress through simple one- to three-minute activities, leveraging color-coded practices and QR codes for digital resources. This card deck supports the development of lifelong skills for stress management and emotional regulation.
Researchers found that hormone treatment reduces abnormal nerve invasion and improves chronic back pain by limiting nerve growth inside damaged spinal tissue. The study suggests that parathyroid hormone can reverse the process by activating natural signals.
Researchers have discovered that endophytic bacteria can coexist with plant cells without harming them, triggering the production of previously unattainable compounds. This method has the potential to expand the diversity of obtainable plant-derived compounds for various industries.
The National Comprehensive Cancer Network (NCCN) has committed to updating its robust information resources for cancer patients and caregivers annually, available in both English and Spanish. The updated resources will provide factual, trustworthy information to guide patients and caregivers towards their best possible outcome.
A global trend of uncommon names has been observed in various nations, including Germany, the US, UK, France, Japan, China, and Indonesia. This increase reflects broader sociocultural changes emphasizing individuality and distinction.
Researchers have quantified the role of obesity in common long-term conditions, showing that losing weight can prevent multiple diseases. Obesity was found to be the main shared cause between ten pairs of commonly occurring conditions, such as type 2 diabetes and osteoarthritis.
Researchers have designed antibodies that recognize a unique sugar found on bacterial cells, providing a potential new treatment for multidrug-resistant hospital-acquired infections. The target of the antibody is pseudaminic acid, a sugar molecule produced exclusively by bacteria and used to evade immune responses.
A new study found that the people of Deep Mani represent one of the most genetically distinctive populations in Europe, with many lineages tracing back to the Bronze Age, Iron Age, and Roman period. The research team discovered that present-day Deep Maniot men descend from a single male ancestor who lived in the 7th century CE.
The World Health Organization has published a practical guide to address the mental health impacts of neglected tropical diseases and stigma that prevents people from seeking care. The Essential Care Package provides clear guidance for governments and healthcare systems to integrate mental health support into existing programs.
A research team led by Dr. Yun-Jo Lee at KRICT successfully demonstrated an integrated process converting landfill gas into aviation fuel, producing 100 kg of sustainable aviation fuel per day with a liquid fuel selectivity exceeding 75 percent.
A study found that cultivating tobacco with its wild relative can erase genetic barriers, allowing normally fatal hybrids to survive. This process, called genome shock, neutralizes lethal gene combinations, potentially leading to the creation of new plant species.
Research suggests that consuming high amounts of ultraprocessed foods is linked to a significantly increased risk of death in cancer survivors. The study, published in Cancer Epidemiology, Biomarkers & Prevention, found that individuals who consumed more ultraprocessed foods had higher rates of all-cause and cancer-specific mortality.
A new study published in Gastroenterology has investigated the link between ulcerative proctitis and rectal cancer, revealing no increased risk in patients with isolated proctitis. The study followed nearly 16,000 people with ulcerative proctitis for over ten years, finding a low incidence of rectal cancer and precancerous lesions.
A team of researchers developed a programmable smart skin out of hydrogel that can be used to encrypt or decrypt information, enable adaptive camouflage and power soft robotics. The material's dynamic control over optical appearance, mechanical response and surface texture can be adjusted using external stimuli.
Soil microbes thrive under winter snowpacks, releasing nutrients critical for plant growth. New research reveals distinct groups orchestrate seasonal nitrogen cycling, transforming organic compounds into forms plants can use.
The BioMARatona Portugal citizen science initiative has achieved an unprecedented milestone with a notable increase in observations gathered and recorded species. Over 5,000 observations and 450 documented species have been accumulated since 2024, mapping diverse types of coastal species.
A deep learning model called DeepBlastoid has been developed to evaluate human blastoids with high accuracy and speed, reducing manual labor burden on researchers. The model achieves accuracy of up to 87% and processes 273.6 images per second, making it suitable for large-scale applications.
A team of researchers at VCU Massey Comprehensive Cancer Center has discovered an innovative way to use a drug already approved in treating irregular heartbeat to selectively target specific functions of enzymes in lymphoma, effectively killing cancer cells and reducing tumor growth with little to no toxicity. The study found that RBF4...
InstaDrive generates precise editing of vehicles and map elements, enabling efficient labeled data generation. It outperforms baselines in FID and mAP, preserving accurate map structures and maintaining multi-view consistency.
A new study from the University of Cincinnati College of Medicine emphasizes the need for updated treatment guidelines on reproductive health among patients with chronic kidney disease (CKD). The survey of 104 nephrologists found that sexual and menstrual health were rarely discussed, highlighting barriers to counseling.
Researchers have developed a new, efficient method for synthesizing benzoxoxetine ligands through a tandem nucleophilic addition/SNAR cycloning reaction. This approach yields oxoheterocyclic phosphine ligands with excellent diastereoselectivity and scalability.
Scientists have discovered a new strategy to prevent the formation of toxic tau tangles in brain cells, which are linked to neurodegenerative diseases. By targeting polyserine, an amino acid chain that drives tau misfolding, researchers have found a potential preventative treatment for tauopathies.
Researchers at Tohoku University developed DIVE, an AI multi-agent workflow that extracts information from images to propose new materials within minutes. The system outperforms commercial models, offering 10-15% better accuracy and coverage of data extraction.
Engineered EVs encapsulate gold nanoparticle-cisplatin conjugates for pH-responsive, targeted delivery to lung cancer cells. TT-Mfn-EVs show enhanced cellular uptake, increased apoptosis and DNA damage, with minimal toxicity towards normal cells.
The Japanese giant salamander's diet shifts from aquatic insects to large prey like fish and crabs as it grows, allowing it to reach the top of its ecosystem. This transition is accompanied by an increase in trophic position, enabling the species to become a superpredator.
Urbanization may be shaping the spotted lanternfly's spread into new environments by allowing them to adapt to heat, pollution, and pesticides. The insects' genetic diversity is lower in the US compared to China, but they are still adapting to local climate conditions.
A recent study by the University of York found that UK polling clerks made mistakes in 36% of cases when tested with real ID documents. The findings challenge the assumption that human checks are a reliable barrier against voter fraud, highlighting the need for improved training methods and alternative security measures.