A new study from Karolinska Institutet identified seven blood biomarkers that predict the risk and progression of multimorbidity in older adults. These biomarkers reflect biological processes such as metabolism, inflammation, and neurodegeneration.
A recent study found that rice viruses actively manipulate plant defense pathways to protect their insect carriers, creating a self-reinforcing cycle. By disrupting the plant's alarm signal, these viruses gain protection from parasitoid wasps, while also facilitating viral transmission.
A new spray-applied polyurea-based nanocomposite sensing coating integrates covalently functionalized graphene nanoplatelets into a two-component polyurea matrix. This enhances processability, weatherability, and establishes a robust conductive network for reliable resistive sensing.
Researchers identified over 200 distinct mutations associated with congenital deafness, including new and family-specific variants. The study provides guidance on communication methods and supports regular ophthalmological follow-up.
Researchers found evidence that dark matter and neutrinos interact, offering a rare glimpse into the universe's darkest regions. The study casts doubt on the long-standing cosmological model, suggesting interactions between dark matter and neutrinos could explain a discrepancy in cosmic structure formation.
A study of over 300 stool samples found that gut-microbe-derived bile acids may play a role in shaping the immune system during early childhood. The findings suggest an imbalance in how gut microbes co-produce these compounds, which could link to signs of type 1 diabetes.
Researchers found that pain-sensing neurons activate tuft cells, which release parasite-fighting immune molecules, initiating an immune response. Silencing or removing these neurons reduces tuft cell numbers, indicating their crucial role in fighting parasites and potentially driving allergic diseases.
A new community asthma program on the Navajo Nation increased asthma-related care and awareness among families, particularly among Diné (Navajo) children. The program, led by National Jewish Health, trained healthcare and school staff to provide culturally respectful asthma care.
A new study reveals significant global growth in digital education research from 2018 to 2023, with the Chinese mainland's academic influence growing rapidly. The study attributes this momentum to strategic policy support, robust infrastructure, and international collaboration.
Researchers identified specific microbial patterns associated with tumor location, genetic features, and patient outcomes. A new Microbial Risk Score (MRS) offers a practical way to translate complex microbiome data into prognostic insight.
Researchers used clumped-isotope palaeothermometry to reconstruct large temperature fluctuations at depths of up to 4,000 meters in the Southern Ocean. These fluctuations occurred simultaneously with changes in oxygen isotopes and Earth's orbital eccentricity, suggesting a climatic forcing.
Researchers have found a rare snapshot of worlds in the process of transforming into super-Earths and sub-Neptunes, the galaxy's most common planetary types. The discovery provides an unprecedented glimpse into the turbulent lives of young worlds, shedding light on their formation.
A recent study using Drosophila as a model organism reveals the involvement of linear ubiquitination in T-tubule biogenesis. The findings highlight LUBEL's role in triggering Amph-mediated T-tubule formation, which promotes membrane tubulation and curvature through self-ubiquitination and positive feedback loops.
The new ECMWF Director-General, Florian Pappenberger, emphasizes the importance of collaboration, innovation, and people-centric approaches. He plans to leverage high-performance computing, AI, and data assimilation to advance weather and climate prediction.
A new smartphone-based system can accurately diagnose sleep apnea in stroke patients, identifying 67% of those with moderate to severe apnea. The portable tool uses sensors and digital biomarkers to monitor breathing, oxygenation, and body position during the night.
A new study from Tel Aviv University reveals that participants consistently preferred options with more positive facial expression mimicry during conversations. Facial mimicry is found to predict choices even when personal taste is not explicitly stated.
The discovery reveals early advanced hunting techniques and demonstrates that humans used arrow poison to increase hunting efficiency. Researchers found chemical residues of poison from the plant gifbol on 60,000-year-old quartz arrowheads in southern Africa.
PeerJ expands its scope to encompass research in Chemistry, Materials Science, and some fields of Engineering. The expanded scope allows for greater collaboration across disciplines, with new opportunities for authors.
New research demonstrates neuromorphic computing's ability to solve complex mathematical problems, including partial differential equations. This technology has the potential to revolutionize energy-efficient computing and tackle real-world challenges.
The Global Workshop on Green Transformation brings together international experts from MIT, EPRI, and DLR to discuss decarbonization and renewable energy systems. The event focuses on the development and implementation of green transformation technologies for a sustainable future.
A team of international scientists led by Dr M. Eleonora Rossi from the University of Bristol reconstructed sponge skeleton evolution, finding that spicules evolved independently in different groups. This discovery challenges previous estimates of sponge origin and sheds light on early animal diversification.
A new study from the University of Eastern Finland explores how regenerative farmers partner with nature in their decision-making processes. The study reveals that farmers prioritize ecosystem resilience and holistic well-being, acknowledging nature's agency and including it in deliberation and decision-making.
Researchers identified dozens of genes that regulate DNA repeat expansion, which accelerates as people age. The study found common genetic variants can speed up or slow this process by up to fourfold, linking it to serious diseases like kidney failure and liver disease.
Children with adverse prenatal exposures showed higher rates of behavior problems, faster cortical thinning, and more depressive symptoms than children with fewer APEs. Researchers found a persistent association between multiple APEs and increased odds of mental health problems as kids grew older.
Researchers identified genes controlling the switch between unicellular and multicellular life forms in marine yeast, revealing a molecular mechanism for clonal multicellularity. The study provides insights into how multicellular life may have evolved from single-celled ancestors.
New research on non-surgical aesthetics reveals these procedures can challenge the skin's ability to stay balanced, defend itself, and heal. The study outlines targeted post-care strategies to help skin recover safely and effectively.
The study of new hominin fossils from Thomas Quarry I in Morocco reveals an African population near the base of the Homo sapiens lineage. The 773,000-year-old fossils provide insights into the shared ancestry of H. sapiens, Neandertals, and Denisovans.
The Global Centre for Asian Women’s Health has partnered with NUS Medicine to host the Women’s Health Impact Tracking (WHIT) platform, which measures progress on closing the women’s health gap across a set of conditions and countries. The platform provides clear, comparative insights to support decision-making and inform policies.
Environmental Health Perspectives has joined the ACS Publications portfolio, ensuring continued publication of high-quality research articles connecting environmental factors to human health. The journal will remain open access with waived article publishing charges until the end of 2026.
An international team of astrophysicists observed four baby planets in the V1298 Tau system forming into super-Earths and sub-Neptunes. The planets' low densities, comparable to Styrofoam, were measured for the first time, providing observational proof.
Researchers identified a novel natural decoy receptor, IL-17REL, that plays a protective role in inflammatory bowel disease. The decoy receptor suppresses downstream inflammatory genes and improves colitis in mice, suggesting its therapeutic potential.
Researchers developed a lightweight, self-powered eye-tracking system that runs off the energy generated through blinking. The system detects eye movements with high precision and can be used to enable people with mobility impairments such as ALS to control wheelchairs or communicate by moving only their eyes.
Researchers discovered that GBS interacts with C. albicans, increasing the risk of severe and fatal infections in newborns and making standard treatments less effective. The co-infection can also reduce the effectiveness of existing GBS treatments.
Duke researchers successfully restored mitochondria in nerve cells, significantly reducing pain tied to diabetic neuropathy and chemotherapy-induced nerve damage. The approach could fix what the team sees as the root problem – restoring energy flow that keeps nerve cells healthy and resilient.
A cohort study found that very high lipoprotein(a) levels increased the 30-year risk of cardiovascular disease among healthy women. Screening for elevated lipoprotein(a) may be warranted in the general population.
A study of chimpanzees reveals that infants take the greatest risks, followed by juveniles and then adolescents. This contradicts human behavior where risky behavior peaks during adolescence. The researchers suggest that human parents' ability to monitor their children may be a key factor in mitigating risk-taking behavior.
Clinicians can effectively counsel patients about firearm injury by discussing risk and safety, building trust, and tailoring interventions. The 3As Framework provides a structured approach to identify patients at risk of harm.
This randomized clinical trial found yoga to significantly accelerate opioid withdrawal recovery and improve autonomic regulation, anxiety, sleep, and pain. The study supports the integration of yoga into withdrawal protocols as a neurobiologically informed intervention addressing core regulatory processes.
Researchers at Utah State University have discovered a new CRISPR system that can precisely target transfer RNA in invading pathogens, which could lead to the development of a single diagnostic test for COVID, influenza, and RSV. This discovery enables the detection and targeting of specific pathogens without damaging host cells.
The study developed subgroup-specific mortality prediction models for high and low ventilatory ratio (VR) subgroups, achieving improved accuracy in short-term mortality prediction. Minute ventilation is a key predictor for the high VR subgroup, while respiratory rate, hypocapnia, and acidemia are unique predictors for the low VR subgroup.
Researchers used ultrahigh-resolution monitoring to track subsurface plumes that rise from lake sediments and fuel surface blooms. The study provides new insights into algal bloom initiation and suggests that sediment-derived precursors can be detected using fine-scale, three-dimensional monitoring systems.
Researchers from Shinshu University used ribosome engineering to modify probiotic Lacticaseibacillus rhamnosus GG, resulting in increased colonization and enhanced immune stimulation. The engineered bacteria exhibit altered surface protein expression and induce higher activation of immune cells.
A new gene therapy has been discovered that targets only pain signals while leaving the rest of the brain untouched, providing hope for people with chronic pain. The therapy eliminates the risk of addiction from narcotics treatments, a breakthrough that could alleviate suffering for over 50 million Americans.
New research reveals that the immune system has a potent weapon against the brain parasite Toxoplasma gondii: an enzyme called caspase-8. This discovery offers new insights into how our bodies control the parasite and may lead to better treatments for patients with compromised immune systems.
The CUNY Graduate Center has received a $1 million grant from Google.org to support the work of Empire AI, a statewide consortium of 11 public and private academic institutions focused on advancing AI integration in higher education. The award will further the reach of a comprehensive assessment of how best to prepare students for an A...
Researchers developed an AI–DFT integrated framework to accelerate materials discovery and design, enabling the efficient exploration of vast chemical and structural spaces. The framework combines the accuracy of first-principles calculations with the speed of AI models, overcoming data scarcity and computational cost challenges.
The Mount Sinai Hospital has received an $8.5 million NIH grant renewal to continue groundbreaking research on long-term outcomes for children with congenital heart disease. The project will unite clinical leaders and registry data from all 25 congenital heart surgical centers across four states to study how differences in health care ...
The meeting report highlights the emerging importance of infection-driven senescence in understanding chronic diseases, including respiratory viruses like influenza and SARS-CoV-2. Researchers found that senescent cells contribute to persistent inflammation and reduced healing, particularly in older adults during chronic infections.
A reconfigurable optical computing platform based on a double-layer liquid crystal structure has been developed to enable multifunctional all-optical image processing. The platform integrates eight types of image processing functions in one go, including bright-field imaging, vortex filtering and edge enhancement, promising substantial...
A study by Norwegian researchers found that adrenaline is highly effective in restarting hearts after hospital cardiac arrests. Administered intravenously, adrenaline works within one minute to increase the patient's chance of regaining their pulse.
Researchers at Case Western Reserve University have developed a new treatment for advanced prostate cancer that targets the PSMA protein. The treatment, called PSMA-1-DOTA, has been shown to effectively reduce salivary gland damage and eliminate severe side effects associated with current therapies.
Nature-based solutions can significantly reduce flood impacts by slowing and absorbing runoff, offering added benefits such as improved air quality and biodiversity. Public awareness and education are key to expanding support for these approaches, with communities needing clear communication about flood risks and benefits.
The collaboration aims to integrate AI-powered analytics with clinical expertise to accelerate data-driven cancer care. MD Anderson researchers will leverage SOPHIAs AI technologies to develop bioinformatics pipelines for rapid RNA-sequencing data interpretation.
Keck Medicine of USC names Christian Pass as its new chief financial officer, bringing extensive leadership and finance expertise to the role. As CFO, Pass will oversee strategic financial planning and collaborations across the health system.
A low-cost, simple robotic apple picker arm developed by Washington State University researchers can pick an apple in about 25 seconds. The inflatable arm is made of a soft fabric filled with air and weighs less than 50 pounds, making it safe to use in orchards.
Researchers discovered a 'one-two punch' of orbital forcing and climate variability driving ice sheet melting in ancient Antarctica. The findings provide new insights into the complex processes shaping our planet's climate history.
Researchers found that pitavastatin directly inhibits the anti-apoptotic protein Mcl-1, a key driver of survival and resistance in TNBC cells. The study showed pitavastatin effectively eliminates cancer stem-like cell populations and reduces tumor growth, angiogenesis, and lung metastasis.
Researchers discover giant virus that infects amoeba, providing further support for nuclear virus origin hypothesis. The new virus, ushikuvirus, has distinct features and unique caps on its surface, which may hold clues to the evolution of complex cells.
Researchers linked oily material to a 2019 oil slick in Brazil, using ocean current models and chemical analysis. The study reveals an additive contaminant effect where plastic pollution can transport oil pollution far beyond its origin.
A new study found that light intensity activities, such as walking or household chores, were associated with a lower risk of death for people with CKM syndrome. The researchers used data from the National Health and Nutrition Examination Survey to compare activity level duration for each CKM syndrome stage.