A University of Auckland scientist has uncovered the fates of chimpanzees who starred in seminal psychological studies. The apes were transported to Europe after the research centre closed down, where they faced harsh conditions, inadequate diet and social upheaval, leading to their premature deaths.
A multidisciplinary consensus updates treatment guidance for prolactinomas, emphasizing early recognition, individualized management strategies, and advanced imaging. The recommendations cover screening, assessment, diagnosis, treatment, and long-term monitoring to improve patient outcomes and quality of life.
Microrobots are designed for highly localized biomedical tasks, including targeted drug delivery, minimally invasive diagnosis, and cell- or tissue-level therapeutic intervention. Magnetic actuation is identified as a promising approach due to its ability to penetrate biological tissues and integrate with medical imaging technologies.
A pilot clinical trial assessed ibuprofen's safety and efficacy as an adjunct to standard TB treatment in patients with pre-XDR-TB and XDR-TB. Participants showed a reduced inflammatory response, indicating potential benefits for host-directed therapies.
A study found that small coral reef fishes form previously undocumented associations with Christmas tree worms and other tube-dwelling worms on Caribbean coral reefs. This behavior is unclear, with potential benefits to both parties, and warrants further investigation into whether it's mutualistic, commensal, or parasitic.
A new study from the Hebrew University of Jerusalem found that low body esteem, problematic social media use, and other factors are linked to addictive-like behavior in women who undergo repeated cosmetic treatments. Nearly 20% of surveyed women met the threshold for moderate-to-severe risk of addictive cosmetic procedure use.
Researchers developed a novel twisted cloverleaf U-tube to improve heat transfer uniformity and efficiency in thermal energy storage systems. The design enhances turbulence kinetic energy, promoting convective heat transfer.
A new study from MUSC suggests that combining flexible testing options and community partnerships can bring populationwide genomic screening to rural and socially vulnerable communities. Over 50,000 adults have completed screening through In Our DNA SC, a program that has reached participants in all 46 South Carolina counties.
A new approach to spinal surgery is gaining traction, with more than 200 surgeries performed under light sedation using local and spinal anaesthesia. This shift aims to reduce risks and speed up recovery for patients, especially the elderly and those with multiple health conditions.
A cohort study in Sweden found that infants without vitamin K prophylaxis at birth have a significantly higher risk of bleeding episodes, including intracranial hemorrhages. The study highlights the importance of intramuscular vitamin K administration to prevent such episodes and the need for continued education on its significance.
Researchers have identified erythrulose, a four-carbon ketose sugar, in the interstellar medium near the Milky Way Galaxy. This detection provides an alternative source of sugars that may have contributed to the emergence of life on Earth.
A new study introduces a flue gas-driven molten-salt heat storage system that enhances operating flexibility in coal-fired power plants, supporting grid stability amid growing renewable energy integration. The system achieved stable transitions between operating states within seconds and showed no significant degradation over one year.
Researchers will address the unstable interface between lithium metal anode and solid electrolyte by engineering ultra-thin films to reduce degradation and resistance. The goal is to improve reliability and stability of solid-state batteries for electric vehicles, enabling faster charging and greater energy storage potential.
Scientists have developed a non-invasive method to predict gene changes causing lung cancer using fluorescence lifetime imaging microscopy (FLIM). This approach can identify specific genetic mutations, such as EGFR, with high accuracy and speed, preserving limited biopsy material for further analysis.
A team of researchers at the University of California San Diego developed a genome-scale reference map detailing how individual genes control human stem cells' functions and identities. This open-access resource enables scientists to build virtual cell models for complex diseases and design patient-specific treatments.
Researchers developed a rapid biosensor for detecting polystyrene nanoparticles, enabling direct detection without labeling or extensive sample preparation. The device can detect particles as small as 50 nm in fresh water and has a low detection limit of 1.3 μg/mL.
Researchers discovered a new epigenetic therapy that remained effective in treatment-resistant acute myeloid leukemia (AML) through activating the Hippo pathway, a tumor-suppressing pathway linked to cancer growth and drug resistance. The therapy, NTX-301, consistently reduced leukemia cell survival more effectively than existing hypom...
Dr. V. Narry Kim's groundbreaking research reveals how RNA tail composition controls stability and translation, opening new paths for durable mRNA therapeutics and vaccines. Her discovery establishes novel regulatory mechanisms of gene expression, enabling antiviral intervention.
Researchers discovered a new framework explaining how cells regulate genes, which operates out of thermodynamic equilibrium and costs energy. The 'optimal switching principle' balances random on/off switching with precise average expression patterns, optimizing information flow.
A new study proposes a switching-based pervasive augmented reality framework that integrates location-based AR, deep learning, and context-awareness to improve landmark recognition. The framework significantly enhanced detection accuracy compared with conventional LBAR systems, while demonstrating high user satisfaction.
A research team led by Iowa State University professors is using machine learning and synthetic techniques to discover new magnetic materials with unprecedented properties. The project aims to create ultra-powerful magnets that can improve energy productivity, reduce electricity costs, and enhance American industrial competitiveness.
Researchers have discovered a soft material that overcomes the trade-off between toughness and fatigue-resistance, making it stronger and more durable. The material's unique architecture enables repetitive energy dissipation mechanisms, allowing it to absorb energy without breaking.
A new University of Michigan poll reveals that 31% of people aged 50 and over have never heard of any mental health crisis line, while 69% are unfamiliar with 988. Despite this, most participants expressed willingness to use these services in a mental health emergency, highlighting the need for increased awareness-raising efforts.
Professor Yaghi has made several global research appointments in the US, South Korea, UK, Italy, Saudi Arabia, UAE, and China to establish an interconnected scientific network for discovery science and planetary sustainability. The Yaghi Science Initiative aims to connect fundamental molecular discovery with real-world solutions for cl...
Researchers identified ZFP384 as a key factor in diminishing microglial reparative functions after stroke. By blocking ZFP384, the study found that microglia retained their reparative properties, leading to enhanced remyelination and synaptic plasticity, and improved long-term neurological function.
Researchers developed a photospike-based TRNG that harnesses unpredictable light-induced electrical charges to generate true random numbers. The device passed all 15 randomness tests and remained stable over millions of cycles, making it suitable for image authentication and deepfake detection.
Mouse study uncovers how oxygen-sensing transcription factors regulate muscle physiology, improving glucose tolerance and producing erythropoietin. The findings suggest that selectively targeting each isoform can lead to different physiological outcomes.
A multidecade study found dementia prevalence significantly increased in Mexico, Peru and Puerto Rico from 9.6% to 14.5%, 7.6% to 11.7% and 10.7% to 15.7%, respectively over two decades. Dementia rates remained stable in Cuba and Dominican Republic.
The study reveals a growing dementia burden in Latin America and the Caribbean, contrasting with declining trends in high-income countries. Strengthened surveillance and investment in dementia care infrastructure are needed to address this uneven distribution of disease.
A new study found that simple weekly electronic symptom check-ins with care teams significantly improves the quality of life for individuals undergoing treatment for advanced cancer. The benefits were notable among patient groups that historically faced barriers to care, including Black patients and those with less formal education.
Researchers at Aalto University have demonstrated the first cyclic quantum heat engine inside a superconducting circuit, enabling technologies needed for high-qubit quantum computers. The study provides a solid proof of concept for superconducting heat engines and could reduce the cost and complexity of large-scale quantum computing.
Scientists engineered an enzyme that selectively recognizes and repairs broken RNA, suggesting that molecular tools needed to preserve the RNA-based genetic code could be furnished by RNA alone. This discovery has implications for understanding the origins of life and developing new biotechnology applications.
A new study by researchers at UCL and GOSH found that the infant airway itself ramps up the immune response, causing damage to lungs. The team tested antiviral drugs, finding that RSV604 calmed the overactive immune response, reducing inflammation levels.
Researchers found that anaerobic decolorization of RB5 dye by Clostridium sp. strain T4 increased acute toxicity, despite efficient color removal. The study highlights the importance of integrating subsequent aerobic or oxidative treatment to achieve further detoxification in azo dye-containing wastewater management systems.
A new study reveals that many influential companies make biodiversity pledges but lack transparency and specificity, hindering accountability. Researchers identified keystone corporations across multiple sectors making commitments, but only 13% met the criteria for robustness.
A global consortium has developed three open-source AI tools to synthesize Alzheimer's literature, surface hidden data insights, and provide peer review feedback. The tools are designed for researchers to harness vast amounts of information toward a shared goal.
A secondary imaging analysis found free water was the most responsive cerebrovascular MRI marker to lifestyle intervention, showing attenuated small-vessel disease-related injury. Intensive lifestyle intervention implemented earlier in late life provided greater microvascular benefits.
Peter J. Denning suggests that Turing's stance on artificial general intelligence and the imitation game has led to the AI mess, with a fundamental flaw in understanding tacit knowledge and its representation problem. He argues that machines cannot grasp human emotions, intuitions, or cultural context, making it impossible to achieve h...
A new global report highlights opportunities to strengthen diagnosis, treatment, and education for women and girls with hematological conditions. The report calls for earlier diagnosis, more consistent treatment, and stronger research and education to improve outcomes globally.
The team created a method to form dome-shaped bumps on nanofilms in water using a computer-guided electron beam, which can be flattened, reshaped, or repositioned as needed. The technology has potential applications in cell movement and nanorobot power systems.
A case study in eastern Ontario highlights the importance of considering tick-borne diseases as part of the infectious workup. Anaplasmosis, a growing public health concern in Canada, can cause symptoms such as fever, weakness, headache, and gastrointestinal distress.
Researchers found a projected increase in temperature-associated suicide mortality worldwide by the 2050s under various climate change scenarios. The study analyzed data from 751 locations across 26 countries and considered regional differences in adaptation to high temperatures.
Researchers from Shanghai Jiao Tong University review advancements in porous transport layer design for proton-exchange-membrane water electrolyzers. Optimizing these layers is critical for unlocking ultra-efficient and durable green hydrogen production technologies.
Researchers developed a self-compliant and adhesive hydrogel interface to form a soft, stable bridge between wearable electrodes and skin. The design enables high-quality ECG, EMG, and EEG recording, maintaining stability during exercise and oily skin conditions.
A study reviews China's development in seismic risk management, tracing the field's progress from disaster response policies to catastrophe risk management and emergency management. The authors suggest strengthening engineering foundations while prioritizing system recovery and adaptation after earthquakes.
Experts call for a transdisciplinary approach to fix aging societies' health and aged care issues. Governance, workforce management, and organizational design must be interconnected to create a shared language and structures needed to bring disciplines together.
A new research project using targeted gene technology aims to interrupt disease-causing signals at the genetic messaging stage. The therapy has shown promising results in early laboratory studies and is being tested in advanced human skin models to improve treatment precision and reduce side effects.
The study examines electrolysis technologies, cost variations, market development rules, and policy mechanisms for green hydrogen production. It highlights the importance of infrastructure, regulatory standards, and investment incentives for widespread adoption.
Researchers at Flinders University discovered that phage virus 'bioaugmentation' can enhance microbial function in polluted soils, allowing for faster degradation of pollutants. The method has potential for restoring polluted environments and promoting microbial resilience.
Researchers have established a strategic framework for triboelectric nanogenerators in military applications, overcoming limitations of traditional sensing systems. TENGs efficiently convert mechanical energy into electrical energy through contact electrification and electrostatic induction, enabling self-sustaining microsystems with h...
Researchers at Okayama University of Science successfully recorded shrimp feeding behavior under simulated microgravity conditions. They found genetic analysis results appeared to be caused by exposure to a microgravity environment.
Recent studies have challenged the classical view of immune checkpoints as local suppressive molecules only active in tumor immunity. Instead, ICs participate in systemic immune homeostasis and are embedded in broader inflammatory and metabolic networks.
A genomic study of the Asian house shrew has uncovered a previously undocumented Indo-Pacific network linking Iran, Yemen, East Africa, and West and Southeast Asia. The research reveals multiple waves of dispersal over a long period, suggesting a far more extensive and complex network of human interaction across the region.
Researchers at DGIST developed an artificial olfactory system that uses metal-organic frameworks to detect and analyze various odors. The system leverages machine learning and deep learning techniques to classify and interpret complex odor signals, enabling accurate disease diagnosis, environmental monitoring, and more.
A research team has developed a highly efficient segmented thermoelectric module that converts waste heat into electricity with remarkable effectiveness, achieving an outstanding peak energy conversion efficiency of 12.7%. This advancement enables the recovery of industrial waste heat and powers deep-space devices.
Researchers have developed a sustainable catalyst platform using biochar from date palm trunk as a support for Ni-based CO₂ methanation catalysts. The catalysts achieved high CO₂ conversion and CH₄ selectivity, even with low metal loading.
Researchers developed a multifunctional flame retardant system that simultaneously improves fire safety, mechanical strength, and wear resistance in epoxy composites. The system, composed of nickel phyllosilicate and polyphosphazene, achieved a V-0 rating and reduced combustion time, smoke production, and CO2 emissions.
Researchers developed a bifunctional catalyst system using silanol nest-enriched silicalite-1 and ZnZrOx, reducing side reactions and increasing para-xylene selectivity. The optimized catalyst achieved high toluene conversion and PX selectivity under various conditions.
Scientists develop laser-assisted method to create precise 2D-TMD diffractive elements with high resolution. The technique enables scalable production of gratings and lenses on various photonic substrates.
A composite sponge material, ZnCuCCS, was developed to remove levofloxacin through adsorption and photocatalytic degradation. The material achieved high efficiency with a total removal efficiency of 90.12%, confirming its practical applicability for wastewater treatment.