Researchers at the Complexity Science Hub developed a mathematical method to analyze armed conflict data, identifying causal links between battles and predicting future conflicts. The approach, inspired by physics and biophysics, reveals how violence spreads like avalanches across Africa and can be applied to other armed conflicts.
SourceComplexity Science Hub·JournalPNAS Nexus·TypeComputational simulation/modeling·DateAug 1, 2023
Researchers have discovered that nuclear pore IDPs form a dynamic barrier that allows essential cellular factors to pass while blocking viruses and pathogens. The team used synthetic biology, multidimensional fluorescence microscopy, and computer-based simulations to study IDPs in living cells.
SourceMax-Planck-Gesellschaft·JournalNature·TypeComputational simulation/modeling·DateMay 2, 2023
Researchers from Penn State and Ohio State University used structural biology, biophysics, and cell biology to understand how pioneer factors interact with nucleosomes. They found that a specific region of the protein helps it access DNA, making it accessible for proteins involved in gene expression.
SourcePenn State·JournalMolecular Cell·TypeExperimental study·DateApr 20, 2023
Researchers from Karolinska Institutet and the Max Planck Institute have identified a new mechanism for DNA folding, revealing how the Smc5/6 complex regulates chromosomal organization. This discovery provides new insights into normal development and disease prevention.
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers found that cholesterol increases the toxicity of a peptide implicated in Alzheimer's progression, altering its secondary structure and forming small, toxic clusters called oligomers. A diet rich in cholesterol may contribute to Alzheimer's disease development by changing the lipid composition of neuronal membranes.
SourceTexas A&M AgriLife Communications·DateMar 1, 2023
Carlas S. Smith receives Biophysical Journal's Paper of the Year-Early Career Investigator Award for groundbreaking work on single-molecule localization microscopy precision. His research provides new opportunities to optimize methods for achieving optimal precision in localization microscopy.
Studies have shown that COVID-19 infection increases the risk of major adverse cardiovascular events, such as heart attacks and strokes. The virus causes changes in calcium channels, oxidative stress, and inflammation in the heart, leading to arrhythmias and myocarditis.
Researchers have developed a tool to predict females' heart response to medications using male data, aiming to prevent deaths from drug-induced complications. The tool uses regression-based models to analyze differences in heart physiology between males and females.
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Researchers at IRB Barcelona have developed a new tool to block protein-protein interactions, a potential therapeutic approach for diseases such as prostate cancer. The synthetic molecules mimic the binding surface of proteins, offering high versatility and stability.
SourceInstitute for Research in Biomedicine (IRB Barcelona)·JournalNature Communications·DateNov 30, 2022
Researchers at Weill Cornell Medicine have developed a new computational method to map the architecture of human tissues in unprecedented detail. This approach enables powerful new diagnostic strategies for a wide range of diseases, including cancer and chronic conditions.
SourceWeill Cornell Medicine·JournalNature Methods·DateOct 31, 2022
A study by OIST Graduate University's Marine Biophysics Unit found that mangroves in the Ryukyu Islands have limited connectivity, making it crucial to protect isolated forests. The research used genetics and oceanography to track propagule dispersal, revealing rare genetic exchanges between islands.
SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalFrontiers in Marine Science·TypeObservational study·DateAug 24, 2022
Jose Rizo-Rey, a professor of Biophysics at the University of Texas Southwestern Medical Center, has been exploring the process of synaptic vesicle fusion using the Frontera supercomputer. His research reveals that specialized proteins are
SourceUniversity of Texas at Austin, Texas Advanced Computing Center·JournaleLife·TypeComputational simulation/modeling·DateJun 20, 2022
The German Research Foundation has granted funding to Johannes Gutenberg University Mainz (JGU) and its strategic alliance partners for four years. Researchers in materials sciences, biophysics, and medicine are working on three collaborative projects with a total funding volume of EUR 35 million. The focus is on developing multiscale ...
SourceJohannes Gutenberg Universitaet Mainz·DateJun 9, 2022
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
Researchers at the Kosinski Group used a combination of cryo-electron tomography, single particle cryo-EM, and integrative modelling to create the most complete model of the human NPC to date, covering over 90% of its core. This breakthrough enables scientists to understand the NPC's structure and function in greater detail.
SourceEuropean Molecular Biology Laboratory·JournalScience·DateJun 9, 2022
Researchers developed a model inspired by vascular biophysics to examine the stability of coastal channel loops. They found that strong interplay between rivers and tides is essential for loop stability, and that flows must constantly rearrange themselves to keep them open.
SourceUniversity of Arkansas·JournalGeophysical Research Letters·TypeComputational simulation/modeling·DateJun 8, 2022
A Texas A&M AgriLife team has described several protein structures of the C1 domain of protein kinase C, providing a reliable guide for designing drug candidates. The research sheds light on how C1 domains bind ligands and could lead to new treatments for diseases such as Alzheimer's, AIDS, and cancer.
SourceTexas A&M AgriLife Communications·JournalNature Communications·DateMay 17, 2022
Researchers at UT Southwestern Medical Center have discovered a new binding site on the STING protein, which plays a critical role in launching immune attacks. This finding could lead to new ways of manipulating STING to prompt stronger immune responses or stem its action in autoimmune diseases.
SourceUT Southwestern Medical Center·JournalNature·DateApr 6, 2022
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
Researchers at Duke University have developed a device that manipulates particles and cells using complex sound waves, enabling selective pairing of individual cells to measure adhesion forces. This technology could lead to personalized medicine by allowing doctors to determine treatment for individual cancer patients.
SourceDuke University·JournalNature Materials·TypeExperimental study·DateMar 24, 2022
Researchers used optical tweezers to study protein folding, revealing entropy and enthalpy levels for the first time. The team discovered that during transition states, the protein skeletal structure is built, but most van der Waals interactions remain unstable.
SourceUniversity of Barcelona·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateMar 23, 2022
A study by Arizona State University shows that certain proteins can act as efficient electrical conductors, outperforming DNA-based nanowires in conductance. The protein nanowires display better performance over long distances, enabling potential applications for medical sensing and diagnostics.
SourceArizona State University·JournalACS Nano·TypeExperimental study·DateFeb 24, 2022
Researchers at RIT have created a biophysical model that can predict changes in cartilage mechanics and function during disease pathways. The model, informed by experimental data, enables noninvasive predictions using MRI scans, potentially reducing the need for invasive procedures.
SourceRochester Institute of Technology·JournalScience Advances·DateFeb 14, 2022
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Researchers developed a fully autonomous biohybrid fish from human stem-cell derived cardiac muscle cells that recreates the muscle contractions of a pumping heart. The device has two layers of muscle cells that work together to propel the fish for over 100 days.
SourceHarvard John A. Paulson School of Engineering and Applied Sciences·JournalScience·DateFeb 10, 2022
A pilot study at UT Southwestern Medical Center found that left ventricular assist devices (LVADs) spurred regeneration in dormant parts of failing hearts. The study's results showed evidence of regeneration in areas considered dead, suggesting a promising avenue for developing regenerative heart therapies.
SourceUT Southwestern Medical Center·JournalCirculation·DateFeb 7, 2022
Scientists at Baylor College of Medicine identified two rare inherited vitamin B12 conditions that share the same gene but exhibit distinct clinical features. The study found that additional genes, including RONIN and HCFC1, are affected, leading to a more complex syndrome.
SourceBaylor College of Medicine·JournalNature Communications·TypeExperimental study·DateJan 10, 2022
Researchers developed a neural network model called STANN that provides new insights into the brain's cellular architecture and functionality. The model predicts precise locations of different cell types and their communication patterns within morphological layers.
SourceBaylor College of Medicine·JournalCell Systems·TypeComputational simulation/modeling·DateDec 22, 2021
Researchers at Goethe University and the Max Planck Institute of Biophysics have gained new insights into how mitochondrial complex I facilitates proton transfer through water molecules. The study's high-resolution structure data enabled computer simulations that shed light on the protein's dynamics during its catalytic cycle.
SourceGoethe University Frankfurt·JournalScience Advances·TypeExperimental study·DateDec 16, 2021
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
This special collection highlights the use of biophysical methods in identifying and characterizing molecules in early drug discovery, including graphene bioelectronic sensing technology and mass spectrometry. It also showcases a fully automated acoustic ejection mass spectrometry technology for high-throughput screening.
SourceSLAS (Society for Laboratory Automation and Screening)·JournalSLAS DISCOVERY·DateAug 31, 2021
Researchers at Karolinska Institutet investigated the protein eIF4A3, which helps cancer cells grow. By blocking this protein, they found that cancer cells stop growing and eventually die. The study suggests a new approach for targeted treatment of colon and sarcoma cancers.
SourceKarolinska Institutet·JournalScience Advances·TypeExperimental study·DateAug 5, 2021
Researchers discovered Piezo1 selectively restrains Treg cells, limiting their potential to mitigate autoimmune neuroinflammation. Inhibiting Piezo1 could lead to new treatments for neuroinflammatory disorders like MS.
SourceUniversity of California - Irvine·JournalScience Advances·DateJul 20, 2021
Scientists from Würzburg, Germany, have identified a protein in the plant Arabidopsis thaliana that detects and translates acidic conditions into an electrical signal. This discovery could lead to more tolerant crops for waterlogging conditions.
SourceUniversity of Würzburg·JournalCurrent Biology·DateJul 6, 2021
Researchers at Boston University School of Medicine discovered that charged biopolymers like heparan sulfate and heparin accelerate amyloid aggregation in various organs. This understanding will guide targeted drug design for deadly diseases such as Alzheimer's, Parkinson's, and type-2 diabetes.
SourceBoston University School of Medicine·JournalTrends in Biochemical Sciences·DateJun 28, 2021
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Researchers used advanced imaging technology to film Zebrafish brains while they were alive, revealing that the activation of stem cells responsible for generating neurons is not random, but rather coordinated. This finding has important implications for understanding brain development and may lead to new treatments for neurodegenerati...
SourceTel-Aviv University·JournalCell Stem Cell·DateMay 11, 2021
Researchers Lynne Maquat and Joan Steitz recognized for elucidating key functions of RNA, a workhorse molecule in cell function. Their discoveries inform RNA-based therapies for diseases like COVID-19 and muscular dystrophy.
Researchers at Einstein College of Medicine developed a topical drug that regenerates and restores function of erectile nerves damaged by radical prostatectomy. The siRNA gel enhanced nerve regeneration and restored nerve function in rat models, restoring erectile function.
SourceAlbert Einstein College of Medicine·JournalJCI Insight·DateApr 19, 2021
Computational biophysics research uncovers mechanism for HIV-1 virus importing nucleotides into its core for DNA synthesis. The study challenges the prevailing view of the viral capsid and reveals an active role in regulating a key step in the virus's life cycle.
SourceUniversity of Texas at Austin, Texas Advanced Computing Center·JournalPLOS Biology·DateMar 31, 2021
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Researchers at UNC-Chapel Hill develop collaborative strategy to test hypothesis on how tiny chemicals formed basic biochemistry four billion years ago. They aim to enhance understanding of cellular processes to detect new disease treatment strategies and inspire life outside Earth.
SourceUniversity of North Carolina Health Care·DateMar 2, 2021
The new journal features short contributions and rapid turnarounds, covering all disciplines of biophysics with an emphasis on methods and techniques. The inaugural Editor-in-Chief, Jörg Enderlein, expects significant potential for the journal to offer transparent and rapid editorial decisions.
Researchers studied cell interactions in a microscopic 'cell collider' and found that normal cells repel each other's protrusions, while cancer cells try to squeeze past each other. The study suggests new approaches for understanding cancer cell behavior and identifying molecular bases for these differences.
SourceLudwig-Maximilians-Universität München·JournalProceedings of the National Academy of Sciences·DateFeb 16, 2021
Researchers from the University of Münster and Düsseldorf provide an in-depth summary of the dynamical density functional theory, a method used to describe interacting particles. The article covers various branches of physics and applications in chemistry, solid state physics, and biophysics.
SourceUniversity of Münster·JournalAdvances In Physics·DateDec 29, 2020
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
Rutgers scientists expand Darwin's theory of evolution to consider DNA stability as an energy code, enabling analysis of the human genome and explaining long-term survival of species characteristics. The study's findings provide new ways to analyze genomes and potentially improve selection of DNA targets for therapeutics.
SourceRutgers University·JournalQuarterly Reviews of Biophysics·DateNov 16, 2020
Researchers have identified a new and evolutionarily conserved pathway responsible for silencing genes in mammalian cells. BAHCC1 protein is involved in the Polycomb pathway, which generates a chemical tag to silence genes, and its high expression is linked to leukemia, challenging current understanding of gene silencing.
SourceUNC Lineberger Comprehensive Cancer Center·JournalNature Genetics·DateNov 2, 2020
A team of biophysics developed a computer model that shows antiseptics cause changes in bacterial membrane structure, making them weaker and more susceptible to external factors. The study's results can help combat bacterial resistance by optimizing antiseptic use and developing new agents.
SourceRUDN University·JournalThe Journal of Physical Chemistry B·DateOct 28, 2020
Carnegie Mellon University has received a $500,000 planning grant to develop AI research and interdisciplinary collaborations in astrophysics, subatomic physics, and biophysics. The university aims to promote cross-disciplinary interactions and encourage new collaborations to advance fundamental fields.
The study sheds light on the SARS-CoV-2 spike protein's flexibility and its impact on viral infection. The research reveals that the stalk is extremely flexible, allowing it to move and search for receptors on host cells.
SourceEuropean Molecular Biology Laboratory·JournalScience·DateAug 18, 2020
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
A non-invasive low-cost ventilator has been designed and tested by UB researchers, providing efficient respiratory support to patients. The prototype adapted to spontaneous breathing rhythm and provided a feeling of breathing relief similar to commercial devices.
SourceUniversity of Barcelona·JournalEuropean Respiratory Journal·DateApr 21, 2020
Recent advances in bioengineering and computational modeling have enabled researchers to study complex biological processes with molecular-level detail. Multidisciplinary work on proteins and modeling highlights challenges as the field develops high-resolution, high-throughput organs on a chip.
SourceAmerican Institute of Physics·JournalAPL Bioengineering·DateMar 3, 2020
Researchers at the University of Ottawa offer a unique tool to accelerate nanopore research development, making it more accessible and affordable. The innovative approach enables fast, low-cost, and automated fabrication of solid-state nanopores, which hold promise for various applications in medicine, IT, and life sciences.
SourceUniversity of Ottawa·JournalNature Protocols·DateJan 14, 2020
Researchers at Columbia University Irving Medical Center have developed a new gene editing tool called INTEGRATE, which uses cryo-electron microscopy to capture high-resolution images of the complex in action. The tool appears to work by targeting DNA for accurate insertion of genetic payloads without introducing DNA breaks.
SourceColumbia University Irving Medical Center·JournalNature·DateDec 18, 2019
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
The German Research Foundation has approved €12 million for the Collaborative Research Centre on selective autophagy. The research alliance aims to better understand autophagy at molecular and cellular levels to counteract imbalances in the system.
Researchers at Weill Cornell Medicine have illuminated the basic mechanism of Piezo proteins, which function as sensors in the body for mechanical stimuli. The discovery provides insights into the roles of Piezo proteins in human diseases and potential new therapeutic strategies.
A study found that chaperone protein Hsp70 inhibits toxic protein aggregates in the androgen receptor, which causes Kennedy's disease and prostate cancer. Hsp70 may be useful as a therapeutic target to treat these conditions.
SourceInstitute for Research in Biomedicine (IRB Barcelona)·JournalNature Communications·DateAug 8, 2019
Researchers from Boston University School of Medicine have discovered a previously unknown role of Serum Amyloid A (SAA) in rapidly removing lipid debris from damaged cells. This process is crucial for tissue healing and survival during acute events such as injury, infection, or inflammation.
A team of scientists has identified 104 high-risk genes for schizophrenia, which may lead to the development of targeted treatments. The study's framework could also help track down genetic suspects in other complex diseases.
SourceVanderbilt University Medical Center·JournalNature Neuroscience·DateApr 22, 2019
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Llinás' research on membrane biophysics and the active neuron concept has significantly advanced our knowledge of neuronal function and behavior. He was recognized for his work on dendritic calcium spikes, electrotonic coupling, and subthreshold oscillations in mammalian neurons.
Dr. Michael Rosen, a leading biophysicist, has been recognized as UT Southwestern's first Allen Distinguished Investigator. His research focuses on protein phase transitions and biomolecular condensates in the cell nucleus.
Researchers developed a gene-suppressing drug that, when combined with an over-the-counter gel, accelerated wound healing in mice. The treatment, tested on mice with skin excisions or burns, showed significant improvements in healing outcomes, including regeneration of hair follicles and collagen networks.
SourceAlbert Einstein College of Medicine·JournalAdvances in Wound Care·DateOct 25, 2018
The Cluster of Excellence PoL aims to understand the organization of living matter and its mechanisms. The researchers hope to shed light on tissue formation and structure, which will provide solutions to pressing bioengineering and health issues.
A standardized protocol for FRET has been established, enabling precise measurement of distances within biomolecules. This breakthrough methodology can overcome size and stability limitations of other structural biology methods, leading to targeted drug development and new research opportunities.
SourceClemson University·JournalNature Methods·DateSep 11, 2018
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
The Biophysical Society has honored 10 distinguished members as 2019 Society Fellows for their groundbreaking work on cytoskeleton filaments, protein folding, single-molecule methods, and cellular dynamics. These individuals have made significant contributions to the field of biophysics.
Elizabeth Rhoades, Associate Professor at the University of Pennsylvania, has been awarded the 2019 Michael and Kate Bárány Award for her outstanding work on structure-function relations in disordered systems. The award recognizes her innovative use of single-molecule tools to gain insights into conformational landscapes.