Margherita R. Fontana, Julie Frantsve-Hawley, and Ariadne Letra were elected as Vice-president, Treasurer, and Representative to the IADR/AADOCR Publications Committee respectively. Their terms commence at the 54th Annual Meeting of AADOCR in March 2024.
Research finds that Streptococcus mutans's collagen-binding protein may induce hematuria and IgA deposition in kidney disease, suggesting a potential pathogenic role. The study suggests a link between oral pathogens and renal lesions.
The University of Kentucky survey found significantly higher dental decay rates for Kentucky children ages 2-5 compared to the national average. Demographic and geographic factors such as region, age, facility type, and rural location influenced tooth decay rates among the children screened.
A research group has identified CLEC1A as a specific receptor for antithrombin, a plasma protein with anti-inflammatory properties. Antithrombin stimulates CLEC1A on human neutrophils to inhibit cell death and ROS production, suggesting a new mechanism of action for this plasma protein group.
A team from the University of Michigan School of Dentistry has patented a new regenerative bone graft material that can regenerate about eight times more bone than existing scaffolds. The breakthrough could transform bone grafts for millions of people who require them, reducing costs and complications associated with traditional methods.
Researchers investigate synthetic oxytocin as a potential pain reducer and addiction curber for susceptible older adults. A two-year study with NIH funding aims to evaluate the effects of oxytocin on acute pain management and opioid use.
Researchers at UF are creating a data biorepository to explore pain pathways and create custom treatments. They're collecting and analyzing human tissue samples and using AI to map and understand the complex relationship between neurons and pain.
A study published in Science Signaling explains the mechanism behind persistent pain related to obstructive sleep apnea. The researchers created a chronic intermittent hypoxia environment in mice and observed an increase in cytokines, which cause sensitivity in nociceptors producing prolonged pain sensitivity.
A new species of fossil penguin discovered in New Zealand shows how penguins' wings evolved into their present form and function. The study highlights the unique combination of bones that allowed penguins to dive and swim, contributing to their ecological diversity.
Researchers at the University of Gothenburg have identified clear stress patterns among children undergoing dental treatment, particularly during anesthetic injections. The study used a sensor tool to monitor hand movements and sweating, revealing that invasive treatments were significantly more stressful for longer periods.
Researchers studied rodent incisors and discovered tiny pockets of iron-rich materials that form a protective shield for teeth, but don't contribute to the orange-brown hue. This finding could lead to improved human dentistry by incorporating small amounts of iron minerals into dental care products.
The International Association for Dental, Oral, and Craniofacial Research announced Enas Belal Abdellatif as the 2024 IADR Newell Johnson Travel Award winner. Abdellatif's research focuses on early childhood caries, oral epidemiology, and behavioral change interventions.
A new study by NYU College of Dentistry shows that silver diamine fluoride (SDF) is an effective alternative to dental sealants for preventing cavities, especially in schools. SDF can increase access to dental care while reducing costs, and its use could keep kids from needing fillings, saving families and the healthcare system money.
The American Dental Association has released updated recommendations to enhance radiography safety in dentistry, emphasizing the appropriate and justified use of dental X-rays. The guidelines also advise against using lead abdominal aprons or thyroid collars, citing evidence that modern digital X-ray equipment and beam restrictions can...
Research found that oral conditions influence subjective psychological well-being in older adults by affecting nutritional status and environmental factors. Maintaining good oral health can improve nutritional intake, leading to better overall health and well-being.
A new diagnostic kit allows dentists to screen for oral squamous cell carcinoma with a simple brush biopsy, detecting genetic signals of the disease with over 90% accuracy. The non-invasive test is less complicated than surgical biopsies and can be performed in under a minute without numbing required.
A University of Otago-led study found that early primates primarily consumed soft fruits, as indicated by dental chipping patterns and cavities. The research, published in the American Journal of Biological Anthropology, analyzed fossils from the Fayum Depression in Egypt and compared them to data from living primates.
A study of Viking Age teeth from Varnhem in Sweden found that 49% of the population had one or more caries lesions, with children's milk teeth being entirely caries-free. The Vikings also underwent dental treatment, including filing front teeth and relieving pressure through holes drilled into molars.
Researchers have identified a small molecule that reverses four types of chronic pain in animal studies without troublesome side effects. The compound, CBD3063, binds to the inner region of a calcium channel, indirectly regulating its activity and reducing neurotransmitter release.
A $4.7 million NIH grant will be used to train dental students and faculty, enhance mentoring, and conduct a clinical research study on Sjögren's disease. The grant aims to find an early biomarker for the chronic autoimmune disorder affecting four million Americans.
A new study finds that targeting the ORAI1 calcium channel may provide a promising approach to treating oral cancer. The study reveals that activating this channel causes an influx of calcium into cancer cells, leading to increased pain sensitivity.
Researchers at Regenstrief Institute and Indiana University School of Dentistry linked electronic dental and health records to provide better care for individuals with Sjögren's disease. This can lead to earlier diagnosis and treatment, reducing the impact of tooth decay and improving overall health.
Researchers successfully created stem-cell derived organoids from human stem cells that secrete three essential enamel proteins. These proteins form a matrix that undergoes mineralization to create a hardened enamel structure. The breakthrough offers hope for developing novel treatments to repair and regenerate teeth.
Researchers at NYU College of Dentistry developed a gene therapy that regulates sodium ion channel activity to alleviate chronic pain. By targeting the specific region where CRMP2 binds to NaV1.7, they were able to reduce sodium influx and quiet down neurons, providing relief from pain in cell and animal studies.
A clinical trial found that hydroxyapatite toothpaste is equally effective in preventing cavities as fluoride toothpaste. The study involved 189 adults who used either hydroxyapatite or fluoride toothpaste for 18 months, with no significant difference in efficacy between the two groups.
A study published in the International Dental Journal demonstrates the use of artificial intelligence to detect signs of gum inflammation, such as redness, swelling, and bleeding, from intraoral photographs with high accuracy. The technology enables population-wide monitoring of gum health and personalized dental care.
Domenick Zero, an Indiana University professor, received the William H. Bowen Research in Dental Caries Award for his groundbreaking research on caries prevention and early detection. His work has improved oral health through innovative methods and tools, shifting focus from invasive treatment to tooth preservation.
Richard Niederman has dedicated his career to generating evidence for oral disease prevention and promotion. He pioneered large-scale school- and community-based oral health programs focusing on fluoride applications.
Researchers from Penn Dental Medicine and UNC identify a key role for Selenomonas sputigena in causing tooth decay, particularly when partnered with Streptococcus mutans. The bacteria form protective biofilms that lead to acid production and cavity formation.
A global analysis of national action plans to tackle antimicrobial resistance reveals a significant gap in preparedness. The study found that many countries lack adequate funding and monitoring mechanisms, hindering effective implementation of policies.
Researchers develop microrobotic system using magnetic nanoparticles to target and eliminate fungal pathogens, achieving rapid eradication within 10 minutes. The nanozyme-based approach offers a potent and concentrated antifungal effect without affecting uninfected areas.
A team of researchers at NYU College of Dentistry has successfully modified an existing anti-nausea drug to target the endosomes within cells, thereby providing a more prolonged analgesic effect. The modified netupitant showed improved pain-relieving properties compared to its original form and other drugs targeting similar receptors.
Researchers at HKU developed a novel smart manufacturing method for dental crowns using generative AI, producing personalised crowns with high accuracy that mimic natural teeth. The 3D-DCGAN algorithm improves the quality of design through internal competition between a generator and a discriminator.
A Tohoku University study found that soft gingiva is more likely to cause inflammation, hindering the development of collagen fibers. This discovery has implications for the development of advanced biomaterials and microdevices to control local inflammation.
A research team developed a new dentine analogue material that can substitute extracted human teeth in laboratory-based mechanical and fatigue tests. The materials were tested for their mechanical strength, elastic modulus, indentation hardness, and fatigue behaviour, showing comparable results to those based on extracted human teeth.
Researchers at NYU College of Dentistry have developed a single score to describe the level of cytokines in saliva, which correlates with the severity of clinical gum inflammation. The study found that higher levels of cytokines in saliva match greater gum inflammation.
Angelo J. Mariotti, the new Dean of LSU Health New Orleans School of Dentistry, has a track record of success in transforming dental education, increasing fundraising, and improving facilities. He aims to enhance faculty development and expand clinics to serve Louisiana's citizens for better oral health.
A study by researchers from Okayama University found that Japanese university students' willingness to undergo regular dental check-ups is associated with their thoughts regarding the health-belief model and oral health behaviors. The study suggests that the perceived benefit of undergoing regular check-ups drives young students toward...
A new jaw surgery technique, segmental mandibular advancement (SMA), has been shown to effectively treat moderate-to-severe Obstructive Sleep Apnea (OSA) in a pilot study. The procedure resulted in a 50% or more reduction in breathing disturbances at night for 58% of patients, with no signs of sleep apnea.
Researchers found that vaping can increase surface tension in lung surfactant, reducing its ability to support proper lung functioning. The study suggests a link between vaping and increased susceptibility to lung injuries, including those caused by respiratory viruses like COVID-19.
Researchers found that activating the non-mutated form of P53 can change the fundamental makeup of cancer stem cells in mouse models of mucoepidermoid carcinoma. This new therapy approach shows promise for treating this lethal form of salivary gland cancer.
A study published in the Journal of Dentistry found that patients with unexplained brain abscesses were three times more likely to have oral bacteria present. The researchers also discovered significantly higher counts of Streptococcus anginosus, a bacterium linked to dental abscesses and infections in internal organs.
Long-term use of systemic antibiotics can alter the gut microbiome, leading to reduced bone mass accrual and impaired skeletal maturation. Researchers found that minocycline therapy causes changes to the gut microbiome, disrupting normal communication between the liver and small intestine.
Researchers found lower calcium and phosphorus concentrations in female primates' bones after giving birth and breastfeeding. The study, which analyzed bone composition over time, shows that reproduction permanently alters the skeleton's dynamic nature.
A new study led by NYU researchers has developed a topical gel that targets the succinate receptor to suppress inflammation, reduce bacterial imbalance, and prevent bone loss. The treatment has shown promise in reducing gum disease symptoms, including inflammation and tooth loss.
A study by HKU Dentistry found that 'positive stress' can induce good changes in tooth stem cells, making them more resistant to injury and disease. The research team developed a preconditioning protocol that modified the cells genetically to mimic low oxygen conditions, which activated protective mechanisms.
A Texas A&M study sheds light on a major health concern for people with Down syndrome, who may not heal from bone fractures. The researchers found that the glue-like cartilage that helps bones heal doesn't form properly in individuals with DS, leading to devastating health impacts.
Researchers at Penn Dental Medicine have developed a microrobotics system to access the root canal with controlled precision, treating and disrupting biofilms. The technology enables diagnostic and therapeutic applications, allowing for personalized treatment plans.
The University of Hong Kong's Faculty of Dentistry has developed an AI-powered approach to automate denture design, allowing for high accuracy and reducing treatment time. The new method uses a 3D Generative Adversarial Network (3D-GAN) algorithm to reconstruct the shape of natural teeth and generate prosthetic teeth.
A new $2.4 million NIH award supports efforts to improve data sharing between dental and medical records, reducing delays in treatment decisions and improving patient health outcomes.
A new US study analyzed tooth survival rates after root canals in a general population, revealing median survival time of 11.1 years. The research found disparities in longevity among geographic regions and the impact of insurance status on treatment outcomes.
The NIH-funded study will enroll 1,050 patients with periodontitis to collect data on the efficacy of antibiotics in treating the condition. The goal is to develop evidence-based clinical guidelines and advance oral health, particularly given the critical need to reduce antibiotic misuse and combat superbugs.
Researchers found a significant decline in certain nutrition markers among denture wearers compared to non-denture wearers. The study suggests that dentists should be aware of this potential impact and provide advice or referrals for nutrition counseling.
Patients with a reported penicillin allergy have higher rates of dental implant failure. Alternative antibiotics prescribed during surgery also linked to increased failure rates. The study suggests that testing for actual allergies may improve outcomes.
A recent study found that sleep bruxism can lead to temporomandibular joint disorders due to increased mechanical loading. The research discovered that specific combinations of tooth shape and location during grinding significantly impact the risk of TMJ problems.
A series of studies by NYU researchers found that e-cigarette users have a distinct oral microbiome less healthy than nonsmokers but potentially healthier than cigarette smokers. The study also reveals altered immune responses, including increased inflammation and suppression of immune reactions.
A Swedish registry study found no increase in endocarditis cases among high-risk individuals since the removal of prophylactic antibiotics in dentistry. The study monitored over 76,000 high-risk individuals and 396,000 low-risk individuals from 2008 to 2018.
A major study has found that spinal anesthesia is not safer or more effective than general anesthesia in patients undergoing surgery for hip fractures. The study, involving 1,600 patients, showed similar outcomes and risks between the two types of anesthesia, contradicting accepted wisdom.
A study by the University of Leeds found that changing drills from air-powered to electric drills can significantly reduce aerosol spray and create a safer environment for patients and dental teams. The research resulted in a 99.98% reduction in virus spread, potentially allowing millions more treatments to be carried out.
The University of West Virginia leads a global initiative to integrate behavioral and social sciences into oral health promotion, aiming to reduce dental disparities and inequities. The effort involves innovative technologies like apps and smartphones to increase access to dental care.