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The Journal of Nuclear Medicine Ahead-of-Print Tip Sheet: September 19, 2025

Faster PET scans show promise for detecting liver inflammation and metabolic dysfunction-associated steatohepatitis. An AI tool combines multiple PET scans to integrate data from different tracers, improving disease insights. New imaging techniques enhance breast cancer surgery and predict recovery after heart attack.

SourceSociety of Nuclear Medicine and Molecular Imaging·JournalJournal of Nuclear Medicine·DateSep 19, 2025

An algorithm that predicts whether pancreatic cancer has spread to other organs could help avoid unnecessary surgeries

A new algorithm developed by Núria Malats and her team can accurately predict the presence of metastasis in pancreatic cancer using medical images. The PMPD algorithm has shown promising results, classifying 56% of metastases with high accuracy and potentially avoiding unnecessary surgeries.

Study assesses cancers in children exposed to medical imaging

A study published in The New England Journal of Medicine found that nearly 4 million children and adolescents were at higher risk of developing blood cancers due to radiation exposure from medical imaging. The researchers estimated that up to 10% of pediatric blood and bone marrow cancers may be attributable to radiation exposure.

SourceUniversity of California - San Francisco·JournalNew England Journal of Medicine·DateSep 17, 2025

Precision targeting of the centromedian nucleus in drug-resistant epilepsy highlighted in brain network disorders

Researchers developed new methods to accurately target the centromedian nucleus for deep brain stimulation in patients with drug-resistant epilepsy. Advanced imaging techniques, such as high-resolution MRI and DTI tractography, improve targeting accuracy by identifying specific brain pathways and neural firing patterns.

SourceBrain Network Disorders Editorial Office·JournalBrain Network Disorders·TypeLiterature review·DateSep 16, 2025

The Journal of Nuclear Medicine Ahead-of-Print Tip Sheet: September 12, 2025

New PET imaging agents show promise for detecting thyroid and neuroendocrine tumors, as well as reversing fibrosis in the heart. Researchers also explored tau PET scans for Alzheimer's detection and SSTR PET/CT for meningioma diagnosis. These advancements hold potential for improving cancer treatment and patient outcomes.

SourceSociety of Nuclear Medicine and Molecular Imaging·JournalJournal of Nuclear Medicine·DateSep 12, 2025

Novel PET tracer detects synaptic changes in spinal cord and brain after spinal cord injury

Researchers developed a new PET tracer that effectively identifies synapse loss in the spinal cord and brain after spinal cord injury. The study found reduced uptake of the tracer at the injury site and in the amygdala and cerebellum, suggesting potential for diagnosing and monitoring spinal cord injuries.

SourceSociety of Nuclear Medicine and Molecular Imaging·JournalJournal of Nuclear Medicine·DateSep 12, 2025

Pre-conception radiation exposure from CT scans increases risk for miscarriage and birth defects

A population-based study found that CT radiation exposure before conception may increase the risk of spontaneous pregnancy loss and congenital anomalies. Women with prior CT scans were more likely to experience miscarriages, ectopic pregnancies, or stillbirths, as well as birth defects in their offspring.

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeNews article·DateSep 8, 2025

Novel accurate approach improves understanding of brain structure in children with ADHD

Researchers developed a new method to correct for variations in brain imaging measurements, reducing bias and increasing the accuracy of studies on ADHD. The traveling-subject method demonstrated reduced measurement bias while maintaining sampling bias, revealing decreased brain volume in critical regions for cognitive functions.

SourceUniversity of Fukui·JournalMolecular Psychiatry·TypeImaging analysis·DateSep 5, 2025

Optical imaging technique could help spot colorectal cancer sooner

A new study introduces an optical imaging technique that uses autofluorescence to detect colorectal cancer in real time, offering a promising tool for improving cancer detection during endoscopic procedures. The technique achieved high accuracy rates and the potential to guide doctors during colonoscopy or surgery.

SourceSPIE--International Society for Optics and Photonics·JournalBiophotonics Discovery·TypeObservational study·DateAug 27, 2025

AI can find cancer pathologists miss

Researchers at Uppsala University have developed an AI system that can detect subtle tissue changes indicative of prostate cancer, missing it from human pathologists. The study found the AI detected cancers in over 80% of cases where pathologists missed them.

SourceUppsala University·JournalScientific Reports·TypeImaging analysis·DateAug 22, 2025

New tracer could enable surgeons to see and hear prostate cancer

A new 'dual-mode' tracer agent shows promise in helping surgeons image and plan prostate cancer procedures while also providing guided surgery with real-time radiation detection. The tracer targets PSMA, a protein highly expressed on prostate cancer cells, offering high-resolution visual guidance and targeted radiation density detection.

SourceUniversity of British Columbia·JournalJournal of Medicinal Chemistry·TypeExperimental study·DateAug 21, 2025

PSMA PET/CT prior to salvage radiotherapy improves overall survival for prostate cancer patients: Real-world data from an entire country

A new study from Denmark shows that men with biochemically recurrent prostate cancer who undergo PSMA PET/CT before salvage radiotherapy have improved survival rates compared to those who do not. This research confirms that PSMA PET/CT is a valuable tool for identifying patients likely to benefit from salvage radiotherapy, potentially ...

SourceSociety of Nuclear Medicine and Molecular Imaging·JournalJournal of Nuclear Medicine·DateAug 13, 2025

World's first MPI-trackable alginate-based microrobot: breakthrough platform enables targeted stimulation, position tracking, and cell delivery without cameras or radiation

Researchers developed an alginate-based microrobot that can be tracked using Magnetic Particle Imaging (MPI) and performs real-time localization, selective thermal therapy, and cell delivery. The robot is powered by a single magnetic actuation system independent of conventional medical imaging devices.

SourceInternational Journal of Extreme Manufacturing·JournalInternational Journal of Extreme Manufacturing·DateAug 12, 2025

Chinese Medical Journal study highlights the role of artificial intelligence in prostate cancer management

Recent AI-based models, such as Asian Prostate Cancer Artificial Intelligence and Galen Prostate, optimize screening and reduce unnecessary biopsies. These models use multimodal clinical parameters and convolutional neural networks to detect prostate cancer and identify aggressiveness of cancer cells.

SourceChinese Medical Journals Publishing House Co., Ltd.·JournalChinese Medical Journal·TypeLiterature review·DateJul 30, 2025

Noninvasive stent imaging powered by light and sound

Researchers have developed a noninvasive method for visualizing stents through skin using photoacoustic microscopy, potentially reducing the need for surgical access and X-ray exposure. The technique uses sound waves generated by light absorption to create high-resolution images of stents in various conditions.

SourceOptica·JournalOptics Letters·DateJul 25, 2025

Beyond the mammogram: Study finds differences between benign and cancerous breast calcifications

Researchers at the University of Illinois found that benign and cancerous breast calcifications have unique structures and formation processes. The study provides a new classification scheme and opens the possibility of treating benign calcifications using certain drugs.

SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalScientific Reports·TypeObservational study·DateJul 23, 2025

Abnormal long COVID PET/MR findings linked to future cardiac and pulmonary diseases

A new study found that long COVID patients with abnormal cardiopulmonary PET/MR findings are at a higher risk of developing heart and lung diseases. The study included 98 patients with persistent cardiopulmonary symptoms after initial COVID infection and showed significant abnormalities in both PET/MRI and dual-energy CT scans.

SourceSociety of Nuclear Medicine and Molecular Imaging·JournalJournal of Nuclear Medicine·DateJul 21, 2025

Pusan National University researchers develop breakthrough deep learning model that enhances handheld 3D medical imaging

A new deep learning model enhances handheld 3D medical imaging by automatically tracking transducer motion without external sensors. The model produces more realistic 3D US images and can reconstruct blood vessel structures using ultrasound and photoacoustic data.

SourcePusan National University·JournalIEEE Transactions on Medical Imaging·TypeImaging analysis·DateJul 15, 2025

Record-breaking human imaging project crosses the finish line: 100,000 volunteers provide science with most detailed look inside the body

The UK Biobank has completed a groundbreaking imaging project, scanning the brains, hearts, abdomens, blood vessels, bones and joints of 100,000 volunteers to understand how diseases develop. The project is already improving patient care in the NHS and beyond, with over 1,300 peer-reviewed scientific papers published based on the data.

New LED-based imaging system could transform cancer detection in endoscopy

A new prototype imaging system combines light-emitting diodes (LEDs) with hyperspectral imaging technology to create detailed maps of tissue properties invisible to conventional cameras. The system shows promise for cancer detection during endoscopy, achieving real-time speeds and high-quality data comparable to reference systems.

SourceSPIE--International Society for Optics and Photonics·JournalJournal of Medical Imaging·DateJul 8, 2025

New MRI approach maps brain metabolism, revealing disease signatures

Researchers at the University of Illinois Urbana-Champaign have developed a new non-invasive MRI approach that visualizes brain metabolism and detects metabolic alterations associated with brain diseases. The technique uses magnetic resonance spectroscopic imaging to provide insights into brain function and disease processes.

SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalNature Biomedical Engineering·TypeExperimental study·DateJul 1, 2025

Optimizing surgical strategies through a nationwide trial: insights from a Chinese Neurosurgical Journal study

A landmark national study in China identifies the most effective treatment strategies for unruptured brain aneurysms, analyzing over 874,000 clinical entries and 42,000 radiological scans. The trial aims to guide patient-specific treatment strategies and inform healthcare planning in China's aging population.

SourceChinese Neurosurgical Journal·JournalChinese Neurosurgical Journal·TypeRandomized controlled/clinical trial·DateJun 30, 2025

Exploring and verifying key thin-section computed tomography features for accurately differentiating granulomas and peripheral lung cancers

Researchers developed a classification system to accurately distinguish granulomas from peripheral lung cancers based on thin-section computed tomography (TSCT) features. Satellite lesions, halo sign, and calcification are indicative of granulomas, while well-defined solid nodules with lobulation raise suspicion for PLCs.

SourceNational Center for Respiratory Medicine·JournalJournal of Thoracic Disease·TypeObservational study·DateJun 28, 2025

Olympians' hearts in focus: groundbreaking study reveals elite rowers' surprising AFib risk

A new study involving 121 former elite rowers from Australia found that one in five develops atrial fibrillation, a condition that can lead to stroke and heart failure. The researchers identified genetic and clinical tools that enable early preventive strategies, highlighting the paradox that AFib is more common among fit athletes.

SourceVictor Chang Cardiac Research Institute·JournalEuropean Heart Journal·TypeObservational study·DateJun 25, 2025

AI-assisted model enhances MRI heart scans

A cardiac magnetic resonance imaging (MRI) scan usually takes anywhere from 30 to 90 minutes. The AI-assisted model developed by Mizzou researchers can turn low-quality MRI heart scans into high-quality images in less time, while improving patient experience and reducing costs.

SourceUniversity of Missouri-Columbia·JournalMagnetic Resonance in Medicine·TypeComputational simulation/modeling·DateJun 25, 2025

Heather Jacene, MD, named president-elect of the Society of Nuclear Medicine and Molecular Imaging

Heather Jacene, MD, has been elected as the new president-elect of SNMMI, with a focus on strengthening the organization and promoting nuclear medicine. She aims to create opportunities for member participation and multidisciplinary collaborations, while raising awareness of nuclear medicine's value to clinical colleagues and patients.

Gary Ulaner, MD, Ph.D., elected vice president-elect of the Society of Nuclear Medicine and Molecular Imaging

Dr. Gary Ulaner has been elected vice president-elect of the Society of Nuclear Medicine and Molecular Imaging (SNMMI), committed to advancing nuclear medicine research and expanding educational activities for professionals. As part of his role, he aims to drive growth and funding for training new radiochemistry and physics professionals.

New PET tracer delivers high-quality images of brain inflammation activity

Researchers developed a novel PET tracer targeting phosphodiesterase 4B to visualize real-time brain inflammation. The tracer showed superior image quality and greater brain distribution compared to existing tracers, highlighting its potential for early diagnosis and personalized therapy in neurodegenerative diseases.

SourceSociety of Nuclear Medicine and Molecular Imaging·JournalJournal of Nuclear Medicine·DateJun 23, 2025