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Stem cells shed new light on how the human embryo forms

A new study using stem cell-based models has revealed how early embryo cells decide between contributing to the foetus or to the supporting yolk sac. Understanding this decision is crucial for infertility treatment using in vitro fertilized (IVF) embryos, as producing the right number of yolk sac forming cells may be critical.

SourceUniversity of Exeter·JournalCell Stem Cell·TypeExperimental study·DateMay 31, 2024

First national study of Dobbs ruling’s effect on permanent contraception among young adults

A new study published in JAMA Health Forum found that following the Dobbs v. Jackson Women's Health Organization ruling, permanent sterilization procedures among young adults increased nationwide, with tubal sterilizations rising twice as high as vasectomies. The study also highlighted the disproportionate impact on young women, who ar...

SourceUniversity of Pittsburgh·JournalJAMA Health Forum·TypeData/statistical analysis·DateApr 12, 2024

Rheumatic diseases associated with childbearing problems

Women with selected rheumatic diseases experience a higher prevalence of childlessness, while risks for pre-eclampsia, low birth weight, and preterm delivery are increased for many conditions. Men with rheumatic conditions also face a higher risk of childlessness, although the impact on fertility varies among different diseases.

SourceOxford University Press USA·JournalRheumatology·TypeObservational study·DateMar 20, 2024

Research exposes security, privacy and safety issues in female technology apps used to track fertility, menopause and monthly cycle

Research highlights significant security, privacy and safety issues in female-oriented technologies, including period-tracker apps and fertility smart devices. The study found inadequate regulations and industry practices in data collection and sharing, posing a potential threat to users' sensitive information.

SourceNewcastle University·JournalFrontiers in the Internet of Things·TypeData/statistical analysis·DateMar 6, 2024

Teenagers need better reproductive health education to tackle parenthood fears

Two new studies by UCL researchers found that nearly half of teenagers are worried about having children due to fear, self-doubt, and lack of education on reproductive health. The studies also highlighted gaps in sex education, with many students expressing concerns about endometriosis, infertility, and the impact of lifestyle on ferti...

SourceUniversity College London·JournalHuman Fertility·TypeSurvey·DateFeb 12, 2024

Study finds preconception stress may affect health of women undergoing fertility treatment

A new study from Mass General Brigham researchers found that women who experienced more preconception stress had higher blood sugar levels during pregnancy, a predictor of current and long-term cardiovascular health. The study also discovered that socioeconomic status was associated with preconception stress and blood glucose levels.

SourceMass General Brigham·JournalJournal of the Endocrine Society·TypeObservational study·DateJan 4, 2024

Is age linked to the picture of the perfect partner?

A large international sample of single women aged 18-67 years was surveyed on their ideal partner characteristics, revealing links between age and preferences. Most attributes were consistently important across ages, but higher age correlated with a preference for confident partners and greater acceptance of younger partners.

SourceUniversity of Göttingen·JournalHuman Nature·TypeSurvey·DateDec 12, 2023

Editorial: Epigenetic aging in oocytes

The editorial discusses epigenetic mechanisms leading to oocyte quality loss, a significant factor in age-related fertility decline. Researchers highlight the importance of understanding this process to address the growing issue of advanced maternal age and its impact on reproduction.

SourceImpact Journals LLC·JournalAging-US·TypeCommentary/editorial·DateAug 30, 2023

Bacterial protein found in the urogenital tract may contribute to reduced fertility, birth defects

Researchers discovered a bacterial protein that contributes to genomic instability and birth defects. The study found that mice exposed to the protein experienced reduced fertility and increased birth defects, shedding light on potential cancer connections.

SourceUniversity of Maryland School of Medicine·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateJul 17, 2023

Endometriosis linked to reduction in live births before diagnosis of the disease

A new study published in Human Reproduction found that women with endometriosis are more likely to experience a reduction in live births before receiving a definitive diagnosis. The research, which included over 18,000 women with surgically-confirmed endometriosis, showed that the number of first live births among these women was half ...

SourceEuropean Society of Human Reproduction and Embryology·JournalHuman Reproduction·TypeObservational study·DateJul 4, 2023

A novel hydrogel may be a beacon of hope for infertility and fertility challenges

A novel hydrogel has been developed to induce endometrial regeneration and elucidate its mechanism, offering new hope for patients struggling with infertility. The gel, made from uterus-derived decellularized extracellular matrix, successfully regenerated the endometrium in mice, creating a favorable environment for embryo implantation.

SourcePohang University of Science & Technology (POSTECH)·JournalAdvanced Functional Materials·DateJul 3, 2023

Happy worms have healthy eggs

A new study found that selective serotonin reuptake inhibitors (SSRIs) improved the quality of aging females' egg cells in roundworms by reducing embryonic death and chromosomal abnormalities. Replication in fruit flies confirmed the findings, suggesting a shared signaling system between species.

SourceNorthwestern University·JournalDevelopmental Biology·DateMay 4, 2023

Time-restricted fasting could cause fertility problems

A new study published in Proceedings of the Royal Society B found that time-restricted fasting affects reproduction differently in male and female zebrafish. After returning to normal food consumption levels, females increased offspring production at the cost of reduced egg quality, while male sperm quality also decreased.

SourceUniversity of East Anglia·JournalProceedings of the Royal Society B Biological Sciences·TypeExperimental study·DateApr 11, 2023

Keeping babies alive will lower population growth – new research

Research led by Professor Corey Bradshaw found that higher baby death rates and larger household sizes contribute to higher fertility rates, supporting the need for greater access to family planning and contraception. The study suggests that increasing access to quality contraception can help reduce infant mortality and curb population...

SourceFlinders University·JournalPLOS ONE·TypeData/statistical analysis·DateFeb 22, 2023

Low birth weight among IVF children not linked to infertility treatments

Research involving nearly 250,000 US families found that medically assisted reproduction techniques, including IVF, do not significantly affect birth weight and pregnancy term. Once family circumstances are considered, the differences between MAR-conceived babies and naturally conceived children become insignificant.

SourceUniversity of Utah Health·JournalObstetrics and Gynecology·TypeData/statistical analysis·DateJan 6, 2022

Sterilizing skeeters

Researchers at UC Santa Barbara have created sterile male mosquitoes using CRISPER/Cas9, a technique that could suppress Aedes aegypti populations. The study found that the mutant males produced no sperm but still suppressed female fertility, making them effective in controlling mosquito populations.

SourceUniversity of California - Santa Barbara·JournalProceedings of the National Academy of Sciences·DateMay 24, 2021

Male chimpanzees prefer mating with old females

Male chimpanzees show a preference for mating with older females, a stark contrast to human behavior where younger females are often preferred. This finding suggests that long-term pair bonding and menopause may have evolved in the human lineage after diverging from chimpanzees.

SourceCell Press·JournalCurrent Biology·DateNov 20, 2006