Articles tagged with Genetic Diversity
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
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Researchers at York University found more pathogens and parasites in urban bee populations, leading to inbreeding and reduced genetic diversity. Conservation efforts focused on green spaces and habitat connectors can help mitigate these effects.
The human pangenome reference combines genetic material from 47 individuals, enabling a deeper and more accurate understanding of worldwide genomic diversity. This improves the detection of variants in the human genome, particularly structural variants that can have important health implications.
The Human Pangenome Reference Consortium expands and updates the human genome project with nearly full genomic data from 47 people of diverse ancestry. Researchers at UW Medicine made significant contributions to drafting the pangenome reference and studying variation within repetitive DNA, which could improve equity in human genome re...
The study reveals that mammals diversified before the K-Pg extinction, driven by continental drifting and stability following the mass extinction. This led to the rich diversity of mammal lineages, including carnivores, primates, and hoofed animals.
A Cornell University-led project has reconstructed Balto's phenotype using ancient DNA extraction and analysis. The research reveals that Balto had a genetically healthier and less inbred lineage than modern breeds, with characteristics adapted to the extreme environment of 1920s Alaska.
Researchers have analyzed DNA samples from over 50 institutions, including Balto at the Cleveland Museum of Natural History, to shed light on extraordinary feats in mammals. The study has identified unchanged DNA across millions of years of evolution and pinpointed genetic variants associated with rare human diseases.
The study highlights 10% of human genome highly conserved across species, linked to embryonic development and environmental adaptation. It also pinpointed genetic variants associated with exceptional traits like brain size and hibernation, and at-risk species for extinction.
A new study finds that modern-day Scottish, Welsh and Northern Irish people share a common genetic heritage with ancient Pictish populations, contradicting long-held assumptions of exotic origins. The research also reveals surprising genetic similarities between Picts and present-day groups in the UK.
Researchers found that individuals within two Xiongnu elite cemeteries exhibited extremely high genetic diversity, confirming the empire as a multiethnic entity. High status individuals showed lower genetic diversity, while those of lower status had higher heterogeneity, suggesting a diverse origin pool.
The American College of Medical Genetics and Genomics (ACMG) has published a statement addressing factors that contribute to bias in clinical genetic testing. The statement highlights three main areas: environmental, clinical, and technical biases, which affect health equity for individuals from historically marginalized populations.
Researchers teamed with Ethiopian farmers to develop new wheat varieties using genomic analysis. Farmers' knowledge played a crucial role in predicting crop yields and selecting optimal traits. The project aims to preserve agrobiodiversity and promote cultural heritage.
A new study led by UCL researchers found evidence of ancient empires' impact on migration in Africa, revealing genetic traces from across the continent. The study used DNA data from over 1,300 individuals from 150 ethnic groups, identifying migrations linked to empires like Kanem-Bornu and Aksum.
Researchers found that a large genetic region responsible for immune responses showed rapid evolution and more Mesolithic hunter-gatherer ancestry, suggesting that genetic variants already present in Europe were passed down preferentially. This suggests that diversity in immune genes may be just as important as adaptation to lifestyle.
Researchers found that the Alba morph in female Colias butterflies evolved once near the last common ancestor over 1.2 million generations ago. The genetic basis of Alba was identified as a regulatory region in DNA, maintained through gene flow and balancing selection.
Research found that inbreeding is a major factor contributing to the decline of the endangered Southern Resident killer whale population. The study, published in Nature Ecology and Evolution, indicates that inbred individuals have lower survival rates and birth rates compared to those with lower levels of inbreeding.
A recent genomic study identifies two genetically distinct Ashaninka subgroups, suggesting a complex history of interactions with neighboring populations. The research also hints at a possible migration from southeastern South America or the Southern Cone, shedding new light on the genetic origins of this Indigenous group.
A new study shows that reversing evolutionary changes in fish stocks like cod can be profitable and help conserve natural genetic diversity. With century-long planning horizons, evolutionary decline can be reversed without significantly reducing profits.
A new study published in Genes, Brain and Behavior found that genetic variants in LINGO2, OAS1, and HECTD1 are associated with different mathematical abilities in Chinese children. The study refined genome-wide association studies of math skills and added population diversity to the literature.
The ENIGMA Initiative aims to bridge knowledge gaps on brain aging factors in developing countries, particularly in India. The study will collect comprehensive data on risk and protective factors through clinical interviews, bloodwork, and brain MRI to identify universal and population-specific predictors of dementia.
Researchers have created detailed genetic maps of green and leatherback sea turtle genomes, providing insights into their unique adaptations and evolutionary history. The study reveals that genetic differences between the two species are mainly found on microchromosomes, which may hold the key to each species' survival.
A genetic study reveals that the Eurasian lynx population in France is critically endangered, with a mere 38 healthy breeding individuals. The low genetic diversity poses a significant threat to the species' survival, and urgent action is needed to introduce new genetic material and protect the remaining population.
A recent NTU Singapore study reconstructed the history of The Sundaland using paleogeography and population genetics to show that rapid sea-level rise drove early settlers to migrate, increasing genetic diversity. This finding provides insight into how climate change can profoundly impact human populations.
A study published in Evolution found that polygamous birds have higher efficiency of natural selection, leading to fewer harmful mutations and increased genetic diversity in small subsets of species with polygamous females.
A study by the University of Tsukuba found that Siebold's beech populations on Okushiri Island have high genetic diversity, suggesting they may have persisted there since before the last glacial maximum. This challenges the assumption that island populations are less genetically diverse due to geographical isolation.
A recent study found that DNA from domesticated chickens has been introgressing into the genomes of wild red junglefowl, leading to a loss of genetic diversity. The researchers estimate that wild birds have inherited 20-50% of their genomes from domestic chickens, which could make them less resilient to environmental changes.
A study led by Northwestern University has connected Caribbean breadfruit to its history, tracing five major lineages to Capt. Bligh's introduction in the Caribbean Sea. The research also found that original breadfruit tree cultivars have survived for centuries and are thriving.
A new study published in Current Biology elucidates 230 years of Caribbean history, identifying eight major genetic lineages of breadfruit and their connections to Oceania. The research highlights the crop's potential as a sustainable and climate-resilient option for food security and sovereignty.
A recent study discovered a legume locus that stimulates promiscuous interaction with soil bacteria, forming nitrogen-fixing nodules with up to 30 different rhizobial strains. This finding opens the door for crop improvement by naturally promoting plant growth through symbiotic associations.
Researchers sequenced the genomes of two endangered sharks, finding low genetic diversity and signs of inbreeding in great hammerheads. In contrast, shortfin makos showed higher genetic diversity and limited inbreeding, offering a glimmer of hope for conservation efforts.
A new study by the University of Bath suggests that diving birds like penguins and puffins are more prone to extinction than non-diving birds. The research found that diving evolved independently 14 times and led to a loss of evolutionary diversity in these species.
Researchers found that genetic diversity is key to successful coral transplantation, and using clones of just 10 staghorn individuals led to better results. The team's findings suggest that diversifying coral outplants is safer than betting on one standout 'super coral' to succeed.
Forests with multiple tree species have been shown to be more productive, as different species fill distinct niches and compete less. Additionally, genetic diversity within each tree species also promotes forest productivity by increasing resource use efficiency and reducing damage from herbivores and fungi.
Research emphasizes the importance of ethnically diverse prostate cancer genomics data and accessible genetic testing. Variations in genomic landscape of prostate cancer were observed in Chinese men compared to Western cohorts, with lower mutation rates in driver genes such as TP53 and PTEN.
Researchers developed a pedigree for aquarium-bred corals, revealing relationships between individuals and identifying genetic differences. The study provides insights into maximizing genetic diversity and adaptability in corals bred for conservation, crucial for their resilience to threats like ocean warming and acidification.
A new study from the Indian Institute of Science sheds light on blackbucks' genetic diversity and survival strategies. Despite human activities restricting their habitats, male blackbucks disperse more than expected, contributing to geneflow, while females stay within native population ranges.
Researchers from OIST have sequenced the genome of pearl oysters, finding key differences between chromosome pairs that could impact immunity and pearl production. The study aims to identify resilient strains for aquaculture, addressing declining pearl production in Japan.
A human genetic study suggests that Madagascar's loss of large vertebrates is linked to the first major human expansion on the island around 1,000 years ago. The study found that a small group of Bantu-speaking African people arrived on the island and led to the rapid growth of the human population.
The Devils Hole pupfish has the lowest genetic diversity among known vertebrates, with 58% of its genomes identical. This lack of diversity may doom the species to extinction as climate change and human impacts increase.
A genetic variant associated with low levels of HDL 'good' cholesterol and high triglycerides has been identified in Polynesian people. This discovery provides new insights into the genetic causes of high cholesterol and may lead to the development of more effective treatment options.
The Global Biobank Meta-analysis Initiative has made significant advancements in expanding genome-wide association studies (GWASs) to include more diverse and representative data from around the world. By analyzing genomic data from over 2 million individuals across four continents, researchers have identified new genetic variants asso...
The study found that genetic variants associated with height are concentrated in regions covering just over 20% of the genome. The variants identified explain 40% of the variation in height for people of European ancestry, and around 10-20% for those of non-European ancestry.
Researchers at the University of Zurich have successfully decoded the genome of Aldabrachelys gigantea, one of the world's two remaining giant tortoise species. The reference genome provides crucial information for breeding programs in zoos to represent genetic diversity and conservation efforts across East Africa and Madagascar.
Researchers have found evidence of genetic diversity in the prion protein gene of endangered Eld's deer, which could provide resistance to chronic wasting disease. The study suggests reducing the frequency of a variant associated with the disease and implementing strict management practices to prevent exposure.
A study reveals that domesticated banana varieties contain traces of three unknown wild ancestors, which were likely hybrids between subspecies and may hold useful traits such as parthenocarpy. The researchers believe these 'mystery ancestors' might still be alive in the wild, particularly in regions including the Gulf of Thailand, Bor...
A study published in Science found that more than one-tenth of the world's terrestrial genetic diversity may already be lost due to climate change and habitat destruction. This could have serious implications for species' ability to adapt to climate change, highlighting the need for urgent conservation efforts.
Researchers at Kyoto University have developed a new method to detect intraspecies genomic diversity, or microdiversity, of uncultivated bacteria. This approach allows for a more comprehensive understanding of microbial ecology and evolution, as previously overlooked variations are now being studied.
A recent genetic study has shed new light on the Anglo-Saxon migration to Britain, revealing that around 75% of Eastern and Southern English populations descended from continental migrants. The integration of these migrant families with the existing British population varied by region and community.
Researchers analyzed genomic data from 30,000 patients and found a highly diverse patient population with ancestries from virtually all continents. This study aims to leverage genetic diversity for discovery in personalized healthcare, especially for underrepresented populations.
Researchers found two distinct populations of the invasive American bullfrog in Brazil, one descended from 1935 introductions and another from the 1970s. The study highlights the need for law enforcement to prevent escape from frog farms.
The University of Guam is conducting a four-person research team's study on the genetics of corals from the Northern Mariana Islands to understand coral population connections, diversity, and adaptations. The study aims to identify potential reserves for declining reefs and assess the impact of warming waters.
Researchers found that genetic makeup of mice affects bacteria in their gut, with heritable species and co-evolution observed. The study's findings could provide new insights into treating human gut-related conditions like Inflammatory Bowel Disease (IBD).
Scientists reconstruct evolution of complex multicellular organisms using genomic data and computational models, revealing gradual changes that began early in evolution. The research reveals distinct paths taken by animal and fungal lineages, shedding light on their shared eukaryotic supergroup.
Researchers found that Marchantia liverworts completely inactivate paternal genes in embryos, ensuring proper development. The mechanism involves Polycomb Repressive Complex 2 and maintains haploid dosage despite the short diploid phase.
A new study found nearly half of Florida panther mutations originated from Texas and Central American pumas, bringing both good and bad genetic material. Researchers emphasize the need to monitor genetic health due to potential risks, especially with small population sizes. Genetic screening for future introductions may be necessary.
A study published in PNAS confirms the single-origin hypothesis for Australia's invasive rabbits, tracing their ancestry back to Thomas Austin's family in England. Genetic diversity declined as the population spread across the continent, revealing a possible genetic advantage that enabled the rabbits to adapt to Australia's climate.
Researchers at Hokkaido University propose two novel hypotheses to address the 'two-fold cost of sex' in sexual reproduction. The first hypothesis suggests that meiosis eliminates harmful mutations through a process known as the 'seesaw effect.' The second hypothesis proposes that anisogamy evolved through 'inflated isogamy,' where lar...
The study reveals that environmental conditions cause RNA structures to change, affecting plant flowering times and potentially leading to more desirable traits. This technology can also be applied to human cells, enabling the design of RNA-based therapies for diseases like SARS-COV-2.
Researchers have mapped RNA diversity in human tissues at unprecedented depth, discovering tens of thousands of novel transcripts. The study used long read sequencing to catalog the genetic code's transcripts, shedding light on how genetic and environmental differences affect gene regulation.
A study found that plant genetic variability controls specific microorganisms, influencing microbial community composition and plant reproductive success. The research used Arabidopsis thaliana genotypes and metabarcoding DNA sequencing to analyze the impact of genetics on leaf microbiota.
Price E. Dickson, Ph.D., received a $407,000 NIH grant to investigate the genetic mechanisms driving social reward and cocaine addiction. The study aims to identify genetic signatures associated with preference for social interactions over addictive drugs.