Articles tagged with Genetic Resources
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers developed a genetically informed dynamic species distribution model to reconstruct the distributional history of wild Piper nigrum from 21,000 years ago. The model identified glacial refugia and patterns of range contraction, expansion, and fragmentation following the Last Glacial Maximum.
The IUCN Microbial Conservation Specialist Group is a new coalition of experts aiming to integrate microbiology into global biodiversity governance. The group's priorities include building a global network, mapping microbial conservation hotspots, developing microbe-specific Red List criteria, and mapping existing projects.
Researchers have mapped the diversity of a globally important pea collection, revealing secrets behind Mendel's famous traits and uncovering agriculturally useful genetic diversity. The new set of gene bank and genomic resources could revolutionize pea breeding and research.
Researchers analyzed DNA from four generations of a large family to understand genetic mutations and their transmission. They found that the rate of de novo mutations varied by over twenty-fold depending on genome location.
A genetic mutation in mice reveals the crucial role of intercellular bridges in meiosis, a specialized cell division process that creates sperm. The study's findings may lead to new treatments and male contraceptives for infertility.
The European Genome-phenome Archive has released the largest ever DNA sequencing dataset on UK child development studies, containing high-resolution data from over 37,000 children and parents. This comprehensive resource can be used to investigate genetic variation's impact on neurodevelopmental conditions and childhood obesity.
The Gene Ontology Consortium has published a new resource of human gene functions, combining experimental data with evolutionary modeling. The PAN-GO functionome lists known functions of over 20,000 genes, providing a complete and accurate picture of gene function.
The Grubhub Community Fund has awarded the American Heart Association a $2 million grant to support food security, technology innovation, and economic resiliency in New York City and Chicago. The funds will be allocated to up to 12 organizations and entrepreneurs focused on improving health equity and expanding access to capital.
Professor Uauy brings extensive experience in wheat genetic research and genomics to lead the institute's ambition to deliver Healthy Plants, Healthy People, Healthy Planet. His vision for plant science will ensure global agricultural challenges are addressed through interdisciplinary science.
Two comprehensive datasets from the Gabriella Miller Kids First Pediatric Research Program explore childhood cancers and congenital disorders. The new datasets aim to identify genetic causes and links between these diseases in children, ultimately supporting the development of improved treatments.
Primary care physicians report significant knowledge gaps and training deficiencies in addressing adoption-related issues. They often rely on guidance for preventative screening and genetic testing, highlighting the need to improve their understanding of mental health and trauma.
The new NCCN Guidelines for Patients: Genetic Testing for Hereditary Breast, Ovarian, Pancreatic, and Prostate Cancer provide evidence-based recommendations for assessing and testing for inherited genetic mutations. The resource aims to inform individuals about their cancer risks based on personal or family history.
Sage has acquired Mary Ann Liebert, Inc., expanding its portfolio of peer-reviewed journals in biotechnology and life sciences. The acquisition enhances reach and impact, ensuring high-quality science continues to make a difference.
The partnership integrates Answer ALS’s Neuromine Data Portal with the AD Data Initiative's AD Workbench, providing a unified platform for data sharing and analysis. This collaboration enables integrative analysis of ALS and Alzheimer’s data, streamlining efforts and enhancing research impact.
The American College of Medical Genetics and Genomics has published a new evidence-based clinical guideline for phenylalanine hydroxylase deficiency diagnosis and management. The guideline provides recommendations for treatment, implementation considerations, research priorities, and economic considerations to improve patient outcomes.
Piangua populations are experiencing a significant loss of genetic diversity due to intense harvesting, reducing their ability to adapt to environmental challenges. The study reveals subtle genetic variations among local populations, highlighting the need for targeted conservation strategies.
A new international canine gene research database has been developed, covering over 100 different tissues and enhancing understanding of hereditary diseases. The database provides a comprehensive resource for studying gene expression in various tissues and prioritizing hereditary factors related to diseases.
A new study reveals that plant species invest less in defense to prioritize growth, with a negative correlation between defense genes and growth traits observed. Researchers identified significant variation among plant species in their investment in disease defense, using open databases to analyze 184 plant species.
Two strains of pathogenic fungi cooperate to share insect victims, dividing territories and utilizing unique specialties. This peaceful coexistence allows them to partition limited resources and adapt to their environment.
A new chromosome-scale reference genome of grass pea has been published, improving on earlier draft assemblies and offering potential for climate-smart agriculture. The updated genome allows for improved breeding and gene editing to develop varieties with improved agronomic characteristics or low toxin content.
A new clinical guideline from the American Stroke Association outlines strategies to support brain health and prevent stroke throughout a person's lifespan. The guideline recommends regular health screenings, identifying risk factors, lifestyle interventions, and medications to reduce the risk of a first stroke.
A new study has identified novel strains of microbes that have adapted to use limited resources in cities, including those found in Hong Kong's subways and skin. These microbes can metabolize manufactured products, posing health risks if they are pathogenic.
Researchers have decoded the genetic makeup of 'Samantha' rose variety to create a powerful resource for future comparative genomic studies. The study found that human selection has significantly influenced the genetic diversity of modern roses, but preserving genetic traits is essential for their health and adaptability.
A new study has identified key factors to build food resilience in Sub-Saharan Africa, including diversifying suppliers, empowering local farmers, and promoting sustainable practices. The proposed blueprint aims to enhance self-sufficiency and reduce reliance on external sources.
A study by the Open Wild Wheat Consortium explains how Aegilops tauschii, a wild grass, contributed to the genetic diversity of bread wheat, enabling its rapid spread across different climates. This hybridization event allowed humans to settle down and form societies.
A comprehensive set of genomic resources for Tausch's goatgrass has been established, shedding light on the evolutionary genetics of wheat. Researchers identified a stem rust resistance gene and a leaf rust resistance gene, which will aid in breeding more resilient wheat varieties.
A decade-long study has discovered a vast untapped genetic potential in modern wheat varieties, revealing that at least 60% of the genetic diversity found in a historic collection is unused. This discovery provides an unprecedented opportunity to improve modern wheat and sustainably feed a growing global population. The study used a cr...
The Kids First DRC has introduced an upgraded data portal to streamline big data search and analysis, improving collaborative pediatric research outcomes. The new portal integrates diverse datasets, including genomic information from the Children's Brain Tumor Network, to foster cross-disciplinary research.
Researchers at HudsonAlpha Institute for Biotechnology have created high-quality genome sequences for three modern upland cotton cultivars, providing necessary resources for breeders. The new genomes revealed genetic material from Pima cotton within modern varieties, enabling efficient selection of progeny with improved fiber quality.
Researchers found a correlation between genetic variations in three telomere-related genes and an increased risk of developing papillary thyroid cancer. The study suggests that individuals with these variants may benefit from closer monitoring for secondary cancers, and highlights the role of long telomeres in cancer development.
A collaboration between students and scientists has successfully sequenced the pear genome, providing valuable resources for pear breeding efforts. The initiative, ACTG, is disrupting traditional academic models by offering students a unique entry point into genomic research.
Researchers identified genetic mutations in peas that enable high iron accumulation, opening doors for biofortification of staple crops like wheat and barley. This breakthrough has the potential to reduce iron deficiency anaemia globally.
Experts recommend breaking with the past to develop a new international mechanism for sharing benefits from digital sequence information. The current system is threatened by the emergence of fast genome sequencing technologies and open access infrastructures.
Researchers developed a mouse model with human-like telomeres by making a single genetic alteration, providing a valuable resource for studying aging and cancer. The discovery highlights the importance of the RTEL1 protein in determining telomere length.
A new study provides comprehensive genomic resources for pangolins, helping protect these threatened mammals from extinction due to habitat loss and trafficking. The data will aid in conservation priorities and management plans, as well as tracing the pangolin trade.
A new genotyping method called Single Primer Enrichment Technology (SPET) was used to investigate the genetic diversity of lettuce and identify genomic regions underlying important agronomic traits. The study revealed over 80,000 high-quality SNPs, allowing researchers to group accessions by type and geographic origin.
A team of scientists has generated and analysed 2000 canine genomes, creating a toolkit for answering complex biological questions. The study reveals genetic diversity in breed morphology, behaviour, and disease susceptibility, as well as the structure of the genome.
A new American Heart Association science advisory emphasizes the need for more resources and best practices in pediatric preventive cardiovascular care. The survey found that many programs are overwhelmed with referrals and have long wait times, highlighting the importance of updated guidelines and strategic action plans.
A new clinical practice resource provides valuable information for healthcare professionals caring for individuals with pathogenic variants in the CHEK2 gene. The resource assesses personalized risk estimates based on family history, specific variant, and other factors.
Researchers at Cornell University have discovered a mutation in the MdLAZY1A gene responsible for the 'weeping' growth pattern in apple trees. This finding could lead to more productive and labor-saving orchards by allowing branches to grow downwards, thereby increasing resource allocation towards reproductive growth.
Researchers developed MemTrax, a continuous recognition test for advanced cognitive impairment screening. The test quickly and accurately quantifies memory processing, storage, and retrieval, providing precise assessments of severity and rate of change over time.
The American College of Medical Genetics and Genomics has released its updated Secondary Findings Gene List (SF v3.2) with three new cardiovascular genes added, including CALM1, CALM2, and CALM3. The list provides guidance on reporting incidental findings in clinical exome and genome sequencing.
Researchers developed a novel DNA marker-based system for identifying Japanese citrus cultivars, enabling quick detection of counterfeit fruit. The method can accurately identify cultivar-specific DNA polymorphisms within minutes, safeguarding Japan's unique citrus industry and its breeders.
Research by West Virginia University professor Sean Tu found that orphan drugs earn pharmaceutical companies almost as much as those marketed to the general public. The Orphan Drug Act incentivizes companies with tax credits, longer patent exclusivity, and easier FDA review for treating rare diseases.
Researchers used cancer proteomics data to identify gene candidates for therapeutic targeting, focusing on protein kinases in uterine endometrial cancer cells. Public molecular resources and multi-omics data analysis can prioritize genes of interest for future studies.
A climate-resilient bean genome unveiled potential to boost food security in drought-prone regions through improved genetic diversity and productivity. The sequencing of the hyacinth bean provides opportunities for targeted breeding to reduce anti-nutritional properties and increase its cultivation.
A new cancer protein profile database has been created by KTH Royal Institute of Technology, mapping 1,463 proteins to 12 different cancer types. This database allows for the identification of individual cancer types using just a drop of blood, providing a promising new approach to cancer prediction and diagnosis.
A study published in PLoS Genetics reveals the mechanism by which a selfish gene in yeast, wtf4, enables its function using a poison-antidote strategy. This strategy involves the production of poison protein that can kill spores, but is countered by an antidote protein produced only by those spores that inherit the drive allele.
The Honeycrisp apple genome has been sequenced, providing valuable resources for understanding genetic traits and enhancing breeding efforts. The U.S. apple industry is worth $23 billion annually, with Honeycrisp being its most valuable cultivar due to its favorable traits such as crispness and cold-hardiness.
The University of Missouri has earned an $8 million grant from the National Institutes of Health to expand its National Swine Resource and Research Center. The center will support research using genetically modified pigs to study human diseases, with a focus on therapies that can be translated from pig models to humans.
A new study from the University of South Australia found that severe vitamin D deficiency is associated with a higher risk of mortality. The research evaluated 307,601 records from the UK Biobank and found that individuals with low vitamin D levels had a significantly decreased risk of death over a 14-year follow-up period.
EURISCO is an international aggregated database documenting over 2 million plant genetic resources across 6,737 genera and 45,175 species. The catalogue provides a central entry point for information on crop diversity, facilitating access to data on crop improvement programmes.
Researchers from Children's Hospital of Philadelphia used advanced mapping techniques to identify causal genes and target pairings in the pancreas linked to type 2 diabetes. The study revealed alpha and acinar cells play a greater role in disease development than previously thought.
The expanded 1000 Genomes Project resource now includes nearly all parent-child trios alongside the original samples, sequenced at high coverage using Illumina NovaSeq instruments. This comprehensive analysis presents significant improvements in variant calls, especially among rare SNVs, INDELs, and SVs.
A new study found nearly half of Florida panther mutations originated from Texas and Central American pumas, bringing both good and bad genetic material. Researchers emphasize the need to monitor genetic health due to potential risks, especially with small population sizes. Genetic screening for future introductions may be necessary.
Researchers developed an AI algorithm using individual ECG heartbeats to accurately predict diabetes and pre-diabetes. The DiaBeats algorithm detected the diseases with an overall accuracy of 97%, irrespective of factors like age, gender, and coexisting metabolic disorders.
Researchers, led by TUM's Senthold Asseng, are exploring ways to close the genetic yield gap of 51% in wheat to meet increasing global demand. Utilizing advanced breeding techniques and interdisciplinary approaches combining genetics, soil, and climate science can lead to richer harvests.
Researchers have created a new DNA atlas that provides insights into how genes in specific cells contribute to coronary artery disease. The atlas identifies over 200 independent genetic markers associated with disease risk, offering a potential roadmap for interpreting non-coding variants.
A reference genome for the wild relative of cultivated tomatoes has been developed to improve crop yields and disease resistance. Researchers have also created online tools to facilitate gene discovery and analysis.
New tools for working with axolotls, developed by Prayag Murawala, hold promise for treating traumatic injury and disease. The axolotl's ability to regenerate tissues and organs could lead to new insights into human health.