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Brain aging may be detected decades before symptoms appear, with links to gut health

A new UCLA study has found a connection between brain aging and gut biology, suggesting that people's brains may be aging decades before symptoms appear. The study, published in eBioMedicine, analyzed brain scans and stool samples to identify a link between brain communication patterns, gut bacteria, and brain aging.

SourceUniversity of California - Los Angeles Health Sciences·JournalEBioMedicine·TypeExperimental study·DateSep 10, 2026

Move over cassette tapes, adhesive tape has memory, too

Ordinary adhesive tape stores a sequence of multiple memories with tunable strength, allowing for simple mechanical calculations. Researchers developed an automated device to create these memories by peeling the tape past designated distances.

SourcePenn State·JournalNew Journal of Physics·TypeExperimental study·DateMay 5, 2026

To flexibly organize thought, the brain makes use of space

Researchers tested Spatial Computing theory by examining neural activity and brain wave patterns in animals performing working memory and categorization tasks. The findings support the theory's predictions, including that alpha/beta waves represent task controls and rules, while spiking activity carries sensory information.

SourcePicower Institute at MIT·JournalCurrent Biology·TypeExperimental study·DateDec 22, 2025

Night waking impacts cognitive performance regardless of sleep duration

A new study published in Sleep Health found that the quality of a night's sleep, rather than its length, predicts how quickly older adults process information the next day. Researchers analyzed data from 261 participants aged 70 and above, who wore devices to track their sleep and completed cognitive assessments six times a day.

SourcePenn State·JournalSleep Health·TypeObservational study·DateDec 18, 2025

Announcing the 2025 Mcknight Brain Research Foundation Innovator Awards in Cognitive Aging and Memory Loss: Leah Acker, MD, Ph.D., of Duke University and Erin Gibson, Ph.D., of the Stanford School of Medicine

Two researchers, Leah Acker and Erin Gibson, have been awarded $750,000 to study cognitive aging through inflammation and sleep. The award aims to understand how the brain becomes vulnerable to cognitive decline and develop practical tools for protecting brain health.

Move more, think sharper

A new study found that staying active through moderate-to-vigorous physical activity is associated with significantly better processing speed, working memory, and executive function in older adults. Even small changes to daily activities can have big impacts on brain health.

SourceUniversity of South Australia·JournalAge and Ageing·TypeRandomized controlled/clinical trial·DateApr 27, 2025

Study shows addressing working memory can help students with math difficulty improve word problem-solving skills

A new study from the University of Kansas explores the role of working memory in word problem-solving for students with and without math difficulties. Researchers found that using interventions to improve working memory can benefit students who struggle with math, reducing cognitive load and improving word problem-solving ability.

SourceUniversity of Kansas·JournalChild Neuropsychology·TypeExperimental study·DateApr 21, 2025

Scientists identify key enzyme in Alzheimer’s disease that links brain inflammation to memory loss

Researchers found that SIRT2, a previously unknown enzyme, plays a key role in excessive GABA production associated with Alzheimer's disease. This process leads to brain inflammation and memory impairment. By targeting SIRT2, scientists can selectively block its harmful effects on memory without affecting other brain functions.

SourceInstitute for Basic Science·JournalMolecular Neurodegeneration·TypeExperimental study·DateApr 14, 2025

Air pollution clouds the mind and makes everyday tasks challenging

Research reveals that even short-term exposure to high levels of particulate matter air pollution impairs cognitive functions such as selective attention and emotion recognition. This study highlights the urgent need for stricter air quality regulations and public health measures to combat the harmful effects of pollution on brain health.

SourceUniversity of Birmingham·JournalNature Communications·TypeData/statistical analysis·DateFeb 6, 2025

Mount Sinai researchers have uncovered the mechanism in the brain that constantly refreshes memory

Mount Sinai researchers discovered a neural mechanism for memory integration that involves replaying experiences, integrating new information with existing memories, and linking memories across time. This finding has implications for understanding adaptive and maladaptive memory processes, such as PTSD.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalNature·TypeExperimental study·DateNov 6, 2024

Recent study reveals reduced maths performance of adults with Dyspraxia

A recent study from the University of Surrey found that adults with Dyspraxia (Developmental Coordination Disorder) exhibit lower math performance compared to neurotypical peers. The research highlights the crucial role of working memory in math tasks for individuals with DCD, suggesting a need for tailored educational approaches.

SourceUniversity of Surrey·JournalActa Psychologica·TypeObservational study·DateSep 17, 2024

Sleep resets neurons for new memories the next day

A Cornell University study finds that sleep resets vital brain function by silencing certain parts of the hippocampus, allowing neurons to reset and enable new learning. This mechanism could lead to breakthroughs in boosting memory and erasing negative memories in conditions like Alzheimer's disease and PTSD.

SourceCornell University·JournalScience·DateAug 15, 2024

Molecule restores cognition, memory in Alzheimer’s disease model mice

A UCLA researcher identified a compound that effectively jumpstarts the brain's memory circuitry, restoring cognitive functions in mice with Alzheimer's disease symptoms. The molecule, DDL-920, works by targeting specific neurons to enhance gamma oscillations, which are critical for memory and cognition.

SourceUniversity of California - Los Angeles Health Sciences·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateAug 7, 2024

‘Mathematical microscope’ reveals novel, energy-efficient mechanism of working memory that works even during sleep

Researchers at UCLA Health discovered a novel, energy-efficient mechanism of working memory that reduces metabolic cost even during sleep. The discovery is published in Nature Communications and may provide an early diagnostic for Alzheimer's disease and related dementia.

SourceUniversity of California - Los Angeles Health Sciences·JournalNature Communications·TypeComputational simulation/modeling·DateMay 8, 2024

Intervention based on science of reading, math boosts comprehension, word problem-solving skills

A culturally-responsive training intervention based on science of reading and math improved comprehension, visualization, and connection-making skills among 66 third-grade English language learners. The program enhanced students' performance in math by utilizing direct and explicit teaching methods, focusing on key cognitive concepts.

SourceUniversity of Kansas·JournalLearning Disabilities Research and Practice·TypeRandomized controlled/clinical trial·DateApr 29, 2024

Good heart health in middle age may preserve brain function among Black women as they age

A new study found that better heart health in middle-aged Black women is linked to reduced cognitive decline and preserved brain function. However, this benefit was not observed among white women. The study suggests that taking care of one's heart may have a positive impact on brain function and overall well-being.

SourceAmerican Heart Association·JournalJournal of the American Heart Association·DateApr 24, 2024

Eye-opener: Pupils enlarge when people focus on tasks

A recent study published in Attention, Perception & Psychophysics found a correlation between pupil dilation and working memory. Researchers at the University of Texas at Arlington discovered that individuals with better working memory had larger pupil dilations during tasks, indicating improved focus and attention.

SourceUniversity of Texas at Arlington·JournalAttention Perception & Psychophysics·TypeObservational study·DateApr 22, 2024

Paper: To understand cognition—and its dysfunction—neuroscientists must learn its rhythms

The study suggests that understanding brain rhythms is critical for developing effective treatments for neurological disorders like schizophrenia, epilepsy, and Parkinson's. Cognition emerges from the coordinated activity of millions of neurons via electric fields, known as brain waves or rhythms.

SourcePicower Institute at MIT·JournalCurrent Opinion in Behavioral Sciences·TypeLiterature review·DateApr 17, 2024

Yoga provides unique cognitive benefits to older women at risk of Alzheimer’s disease, study finds

A UCLA Health study suggests Kundalini yoga can improve cognitive function, memory and brain health for postmenopausal women. The study found that yoga prevented brain matter decline, reversed aging and inflammation-associated biomarkers – improvements not seen in a group who received standard memory training exercises.

SourceUniversity of California - Los Angeles Health Sciences·JournalTranslational Psychiatry·TypeRandomized controlled/clinical trial·DateFeb 26, 2024