The Biophysical Society condemns the mass dismissal of the National Science Board, which plays a crucial role in shaping US science policy. The board's absence jeopardizes fundamental research and development, hindering the country's global leadership in science and technology.
The study reveals that rising temperatures are accelerating permafrost thaw and glacier retreat on the Tibetan Plateau, forming thermokarst lakes that release ancient, long-frozen carbon as potent greenhouse gases. The research highlights the urgent need for typology-based management strategies to mitigate these emissions.
The study reveals that the interplay between EZH2 and Ca2+ signaling pathways can be harnessed to improve CAR T-cell efficacy in tumor control while preventing graft-versus-host disease. This balance allows for effective cancer treatment while minimizing transplant rejection.
A new genetic mechanism has been discovered in eggplants, allowing for precision breeding and maintaining attractive pigmentation under variable growing conditions. The study identified a previously unknown promoter switch in the SmMYB113 gene, which enables anthocyanin production even without light.
A new study suggests that seasonal influenza vaccines may significantly reduce the risk of death from H5N1 infection. The study found that vaccines including a specific component, neuraminidase N1, reduced H5N1-related mortality by approximately 73 percent in vaccinated animals.
Researchers at Mayo Clinic have developed a blood-based method to detect germ cell tumors, the most common type of testicular cancer, including cases that do not show up on standard blood tests. The new test, GCT-iSIGN, identified 93% of individuals with germ cell tumors and correctly ruled out cancer in 99% of those without.
A new review proposes a prevention-focused framework for understanding Parkinson's disease risk, highlighting the role of early-life vulnerability, environmental exposures, and resilience factors. The study suggests that susceptibility to PD may begin earlier in life through interactions between biology and environment.
Researchers found higher rates of suicidal ideation among individuals who died by firearm suicide after 2020, but lower engagement in mental health treatment. Demographic shifts also occurred, with more young, male, and minority decedents, highlighting gaps in suicide prevention strategies.
Researchers discovered that ultrasoft elastic materials generate a V-shaped wake similar to boat wakes, blurring the distinction between wave behavior on solids and fluids. This finding could lead to new approaches for soft-tissue diagnostics and understanding the properties of natural and engineered soft materials.
Researchers at Rice Biotech Launch Pad are developing an encapsulation platform to protect transplanted pancreatic islet cells from immune attack. The approach aims to reduce scarring and inflammation, making it possible for people with Type 1 diabetes to manage their condition without long-term immunosuppression.
Artificial platelets have been developed that remain stable and effective after a year at room temperature and two months at high temperatures. This technology could enable direct injection of synthetic platelets into bone marrow to treat life-threatening bleeding in remote areas or disaster zones.
A new chemical model developed by researchers at GEOMAR accurately predicts iron chemistry in the South Pacific Ocean, taking into account diverse organic matter properties. The findings improve understanding of the marine iron cycle and its implications for climate change.
The study reveals that the structural transition of SnTe originates from atomic-level mismatches between S/Se and Sn. SnTe retains a cubic structure due to its similar physicochemical properties with Sn, enabling it to exhibit remarkable advantages in conductivity, tap density, and lithium-ion diffusivity.
Harvard engineers develop new method to preserve long molecular chains in natural rubber, resulting in composite materials that are both stiff and tough. The innovation has the potential to cut waste, reduce tire dust pollution, and open new avenues for high-performance elastomers.
Digital Science has upgraded its world-leading Dimensions Research Security platform with a full workflow solution addressing growing volumes, fragmented tools, and rising compliance pressure. The new solution enables proactive research security work with reduced manual effort, making it easier to generate, customize, and access reports.
A new study found that Catholic men are the most likely group to engage in sports gambling in the US, contradicting the long-held assumption that religion discourages such behavior. Researchers also discovered that people who infrequently attend religious services are more likely to gamble on sports than those who attend regularly.
Researchers agree on core elements of ACLF development, including chronic liver disease triggers, acute insult, and extrahepatic organ failure. A new three-stage mouse model supports testing of potential therapies, highlighting impaired liver regeneration as a key driver of disease progression.
A Rutgers study examines the challenges and opportunities of community violence intervention programs in semi-rural communities. The research highlights the importance of flexibility, strong partnerships, and local relationships to effectively respond to violence in broader geographic areas.
Researchers from NUS engineered bacteria to restore metabolic balance across the gut, liver and brain, reducing brain toxins and preventing neurological symptoms. The approach preserves the natural diversity of the gut microbiome and has shown promising results in long-term safety studies.
A study published in PLOS Medicine found that age at initial diagnosis, sex, and type of first cancer significantly affect the risk of developing a subsequent primary cancer. Older age and male sex were associated with a higher risk, while survivors of lung, bladder, and skin melanoma were also at increased risk.
Scientists create a novel nano-delivery system that boosts NAD+ synthesis and reduces consumption, rapidly restoring energy metabolism in damaged kidneys. The approach halts disease progression and prevents chronic kidney disease, offering a promising drug development platform for AKI and other energy metabolism disorders.
Rivers are warming, losing oxygen, and accumulating greenhouse gases, with estimated annual emissions of 1.5 billion metric tons of CO2 equivalent. Climate change and land use drive these processes, but protecting rivers can help mitigate global warming.
A recent survey found that 31% of 16-year-olds and 39% of 18-year-olds had sent sexually suggestive photos or videos. Most teens receive these messages from strangers, while those in relationships often send them to their partners.
Researchers introduce generalized perfect spatiotemporal optical vortices with topological-charge-independent sizes and fully controllable geometric shapes. The new method achieves higher modulation efficiency and improved energy utilization, exceeding 90%.
A nationwide ecological study found a statistical correlation between fewer psychiatric beds and higher suicide rates in Sweden. The study suggests that investing in outpatient care may not be enough to prevent suicides, highlighting the need for further research into healthcare resource allocation.
A team of researchers designed a bismuth-coordinated melanin material to shield against radiation and alleviate acute radiation syndrome (ARS), with promising results in mouse experiments. The material showed stronger shielding and antioxidant effects, improving survival rates from 20% to 60%.
Researchers found that plants can acquire essential nutrients like phosphorus and iron from atmospheric dust settling on their leaves. This discovery suggests an important new pathway for plant nutrition and ecosystem functioning, particularly in nutrient-limited ecosystems.
Researchers have discovered a pattern in ultra-low temperature measurements of quantum Hall effect states, which can be explained by the composite fermion (CF) theory. The findings propose a connection between CFs and the observed states, providing a new understanding of fractional quantum Hall states.
Researchers at Beihang University developed a hierarchical modular film system that couples biomimetic temperature-humidity sensing with dual-mode heating and ultrahigh EMI shielding. The system delivers exceptional metrics, achieving stable signal transmission and collaborative heating under diverse conditions.
Researchers at Linköping University developed a digital twin model to predict alcohol consumption and drinking patterns. The tool uses data from exhaled breath, blood, and urine samples to generate individualised results, providing a more accurate picture of when a person last drank.
A comprehensive survey of 4,000 adults in northern China reveals alarming gaps in public knowledge about preventing tick-borne diseases. Rural residents and high-risk groups paradoxically show the lowest protective awareness, highlighting a critical need for targeted health education interventions.
Researchers from China have successfully demonstrated CRISPR/Cas genome editing in nonregenerative cotton via sexual hybridization, opening a novel technical avenue for genetic improvement. The approach eliminates toxicity in cottonseed protein, enabling valuable resource utilization and advanced biotechnologies.
Researchers found that hydrogen in LaH3 can tunnel through energy barriers rather than surmounting them, with quantum tunneling becoming dominant at approximately 71 K and increasing to 308 K for single-ion migration. This study clarifies why classical models fail to capture key aspects of the underlying physics.
Researchers developed curvature-optimized multilevel SERS substrates using femtosecond laser shaping, exhibiting enhanced Raman signal intensity and uniformity. The substrate features triple cross-scale structures with flexible shape parameters, promoting dimensionally ordered hot spots for improved detection sensitivity.
Researchers found that exercising to self-selected music boosts endurance by nearly 20%, allowing individuals to tolerate sustained effort for longer. Participants cycled for an average of 35.6 minutes with music versus 29.8 minutes in silence, with no change in heart rate or lactate levels at the finish.
Researchers at Kyushu University developed a new mathematical model that simulates oxygen transport by red blood cells through tiny blood vessels and their delivery to surrounding tissues. The findings show that RBCs can naturally adjust the amount of oxygen released based on local requirements.
A new paradigm shift in cancer research defines valid primary study endpoints for oligometastatic disease, focusing on treatment-free time and minimal side effects. The consensus paper establishes two new metrics: STFS (Start or Switch of Systemic Therapy–Free Survival) and pPFS (polymetastatic Progression–Free Survival), which capture...
Researchers at the University of Cordoba developed MAPLID, a tool that maps city structures and pace based on how residents use their cell phones. The multi-label classification provides information on population density changes and traffic patterns.
A new study published in The Innovation Medicine found that long-term exposure to air pollution significantly increases the risk of cardiovascular disease (CVD) in individuals with cardiovascular-kidney-metabolic (CKM) syndrome. Exposure to fine particulate matter and cooking fuel was linked to a higher risk of CVD.
A recent study has developed an analytical model of downburst wind fields, which reproduces key observable features while adhering to fundamental mechanical principles. The model proposes a framework for assessing train overturning due to downbursts, with high train speeds identified as the most significant contributor to increased risk.
Researchers discovered Trichobilharzia franki parasites in Lake Alqueva, marking the first confirmed record of avian schistosomes in Portugal. The finding highlights potential cercarial dermatitis risk in Europe's largest artificial reservoir.
A new study examines the One Health approach for tick-borne disease management in the Middle East and North Africa region. The research highlights critical gaps in current control strategies, including limited understanding of acaricide resistance patterns and incomplete epidemiological surveillance systems.
A new tool has been developed to fund wetland conservation and restoration projects through verifiable Coastal Resilience Assets. This approach uses engineering methods to quantify the impacts of conservation and restoration projects on property value protected from flooding, providing a clear and tangible use case for asset buyers.
Researchers at LMU Munich develop a surface treatment method to optimize the molecular contact in perovskite solar cells, resulting in improved efficiency, reproducibility, and stability. The approach provides a scalable solution for industry-compatible fabrication workflows.
Scientists have uncovered an unexpected way cancer cells generate cancer-driving proteins by cutting RNA into shorter fragments. This process, termed as RNA dicing, enables the production of a truncated form of the JAK1 protein that remains highly active and can promote tumor growth.
Researchers found that urban birds flee sooner when approached by women compared to men in a European study. The study involved over 2,700 observations across five countries and 37 bird species, revealing that birds can recognize the sex of approaching humans.
A study by University of Barcelona researchers has identified a key protein called Polμ that enables macrophages to survive at the site of inflammation. This discovery could have implications for understanding and treating autoinflammatory diseases and conditions such as septic shock.
The 2026 Semmelweis-Richter Journalism Award is now open for entries, with a focus on high-quality health journalism and its impact across Europe. Journalists can submit articles in two categories until June 9, 2026, with a total prize fund of €45,000.
Scientists developed a Tuneable Magnetic End Effector to control microrobots for targeted and minimally invasive healthcare. The technology enables precise delivery of therapies directly to diseased tissues, reducing damage and side effects.
Researchers developed a multi-physics machine learning framework that improves stress prediction accuracy by integrating electrical resistivity. The model achieved significant reductions in mean absolute error and improved coefficient of determination, making it a promising approach for real-time monitoring of compressive stress in UHPC.
Researchers at KAUST have developed a resilient renewable energy system capable of meeting electricity demand during extreme weather conditions in hot desert regions. The system combines concentrated solar power, photovoltaic panels, wind turbines with battery and thermal storage, reducing CO2 emissions by 330,000 tonnes annually.
The kinase field offers significant therapeutic opportunities, with many understudied kinases waiting to be explored. Recent advances in chemical probe development and resource availability have led to a shift towards more systematic exploration of previously neglected targets.
A new study by the University of East London found that newer blockchain systems significantly reduce energy consumption, from 100-150 TWh per year for Bitcoin to negligible amounts. This shift has already led to reductions in network energy use and enables wider adoption at scale.
Researchers identified thermotolerant Campylobacter spp. in South American camelids (SACs) with a prevalence of 3.2%, revealing species-specific differences in bacterial colonization. Elevated antimicrobial resistance was detected, posing public health concerns.
Researchers developed a new imaging method to visualize how food spreads through ant groups in real time, offering insights into collective health and potential early warning signs of disruption. The technique allows for precise measurement of food distribution patterns across various species.
Researchers have developed a series of carbonyl-rich carbon sphere catalysts with unique wrinkled surface architecture, significantly enhancing the catalyst's performance in hydrogen peroxide electrosynthesis. The optimized catalyst achieved high H2O2 selectivity and efficiency.
Researchers studied evolution of Scalesia genus, finding lobed leaves evolved through multiple genetic pathways. The study highlights the flexibility and creativity of evolution, with new species forming and populations showing large genetic differences.
Researchers found that small understory trees can initially buffer climate change more strongly, but their long-term carbon storage capacity could be restricted by phosphorus availability. The study suggests a critical trade-off between short-term growth and long-term sustainability.
This study investigates the effects of high-volume fly ash on early-age characteristics and hardening properties of concrete. The results show that fly ash can improve fresh concrete workability but delays setting time. However, moderate fly ash replacement achieves excellent long-term strength and stiffness.
Researchers introduce Radon transform-based flow measurement (R-Flow), a contrast-free ultrasound method that visualizes blood flow dynamics at the microvascular scale. The technique captures complete 2D flow patterns and demonstrates high accuracy in detecting pathological changes in diseases like cirrhosis.