A new study recalibrates the argon-argon dating method, allowing for highly precise and accurate dating of volcanic eruptions. This improvement enables geologists to attach accurate dates to geologic events, including past eruptions of volcanoes that threaten urban areas, and helps ground-truth other dating methods.
Plant roots detect injury through tiny proteins, triggering electrical and calcium signals that activate defense mechanisms. Repeated bursts of calcium signals can make plant roots temporarily less sensitive to subsequent damage, coordinating how plants respond to repeated or nearby damage.
Researchers found that microorganisms could tolerate the conditions in Enceladus's ocean better than previously thought, increasing the probability of finding evidence of life on Saturn's moon. The discovery provides new insights into the search for life in space, with implications for future space missions to Enceladus.
Researchers at the University of California San Diego have developed a new approach to switch magnetic states using light, which could lead to faster and more efficient data storage. By shaping and shrinking light, they were able to overcome limitations of previous methods and achieve optical switching in thicker magnetic materials.
Researchers at the University of Montana are using birding as a low-pressure setting to encourage communication and conversation among stroke survivors with aphasia. The Big Sky Aphasia Program, which combines community- and curiosity-driven bird-related activities, has shown promising results in improving outcomes for participants. Th...
A study published in Scientific Reports documents the first molecular characterization of Marfan syndrome in domestic cats, Gary and Shaggy. The feline siblings' condition was caused by a variant of the FBN1 gene, but their partially disrupted gene allowed some normal function to remain, enabling them to survive into adulthood.
Researchers are using mathematical modeling to examine the influence of common metals on protein aggregation in Alzheimer's disease. A new model developed by Mississippi State University Associate Professor Shantia Yarahmadian successfully reproduced patterns seen in laboratory experiments, providing insights into potential therapies.
Chemical signatures in Ediacaran fossils indicate a long-standing symbiotic relationship between early animals and microbes, dating back to 635 million years ago. This ancient chemosymbiosis allowed early animals to survive and spread throughout the ocean, setting the stage for the evolution of complex life forms.
Bone complications in sickle cell disease include early-onset osteoporosis, compression fractures, and avascular necrosis. Research aims to investigate how inflammation leads to bone complications and identify if bone cells drive musculoskeletal pain.
The University of Kansas has received $5.8 million in NIH funding to further its Chemical Biology of Infectious Disease center, which aims to develop targeted treatments for antibiotic-resistant pathogens. The center's collaborative approach will focus on protecting the beneficial microbiome while defeating resistance mechanisms.
A randomized controlled trial found that three months of Transcendental Meditation practice significantly increased happiness, resilience, and self-efficacy among rural Lebanese women while reducing perceived stress. The study showed that Transcendental Meditation may offer women an additional way to cope with daily life pressures.
A team of researchers from the University of Nebraska-Lincoln has discovered that hafnium oxide is inherently antiferroelectric, a rare quality found in few materials. This breakthrough could lead to the development of high-performance capacitors, solid-state cooling systems, and more efficient computer memory.
The new journal will feature theoretical, empirical, and methodological research on disinformation, as well as an Interventions and Commentary section. It aims to critically interrogate disinformation and its impact on societies, with a focus on international perspectives and collaboration.
A UCLA study found that a dietary supplement, Ca-αKG, reduced lung tumor growth in female mice, but increased tumor growth in male mice. The supplement activated genes associated with better outcomes in women with lung cancer, but had the opposite effect in men.
Recent studies published in The Journal of Nuclear Medicine have investigated new treatments for liver fibrosis, thyroid cancer, and prostate cancer, including the use of PET tracers and radioactive iodine therapy. These studies have shown promising results, including improved imaging and biochemical responses, and increased radiation ...
Researchers at UT MD Anderson Cancer Center have made significant breakthroughs in cancer treatment, developing a targeted antibody that improves outcomes for patients with advanced lung cancer who have faced treatment resistance. The treatment, which combines ivonescimab with chemotherapy, has been shown to extend disease control and ...
A study of 2.7 million marathon performances found that higher air pollution levels were associated with slower finishing times, particularly in recreational runners. Nitrogen dioxide levels were strongly linked to finishing times, with effects six times larger for recreational runners than elite athletes.
Matthew G. Nayor, a renowned cardiologist, has been named medical director of the Framingham Heart Study, a world-renowned cardiovascular research project. He will oversee the capture and adjudication of clinical events, leveraging AI to enhance oversight and classification of participant outcomes.
The study found that pre-existing immune cells capable of recognizing and attacking donor-derived CAR T cells can lead to immune rejection, while certain CAR T cell populations with
ICFO researchers have achieved the longest storage time for single photons in a solid-state quantum memory, storing them for up to 180 microseconds. This was made possible by the spin rephasing protocol, which counteracts decoherence effects and restores the collective spin excitation.
This book explores the role of bioenergy in addressing climate change, energy security, and environmental sustainability. It presents a comprehensive examination of bioenergy technologies, their production, optimization, and assessment, highlighting their contribution to a low-carbon economy.
Researchers at NUS CDE have developed a reconfigurable transistor that can switch between filtering image data and performing AI network functions, reducing energy consumption and improving accuracy in handwritten-digit recognition simulations. The device uses a spiking neural network-in-logic architecture to selectively pass relevant ...
A new study by Ateneo researchers explores the cost-effectiveness of AI-assisted chest radiograph interpretation in isolated and disadvantaged Filipino communities. The study finds that AI-assisted interpretation is estimated to be more cost-effective than manual interpretation, with a potential annual cost savings of Php 877,330. The ...
The book explores how generative AI is reshaping retail through AI-driven capabilities, creating value, and meeting evolving consumer expectations. It covers topics like AI-powered personalization, conversational commerce, and intelligent supply chains, offering a balanced perspective on AI-enabled retailing.
This book explores the convergence of plant-based medicine and nanoscale delivery systems to address pressing health challenges. It presents new approaches for treating conditions like depression, anxiety, and metabolic disorders, and showcases successful applications of nanophytomedicine.
A Cornell University study found that consumers don't consistently judge wine quality based on color, with hybrid grape wines ranking among the most visually appealing. The research, published in the American Journal of Enology and Viticulture, also showed that taste and aroma are more important factors in overall quality perception.
A new special issue explores how and why we express emotions, and how humans and animals shape their behavior and social worlds through smiles, glances, and body language. Researchers examine the origins and development of emotional expressions, their roles in behavior and social lives, and their commonalities across species.
An international study found that radiotherapy significantly reduces the risk of recurrence in atypical meningiomas after complete surgical resection. The study, involving 157 patients, showed a 14% recurrence rate in the radiotherapy group compared to 30% in the observation group.
Researchers are exploring biomarker-guided patient selection and combination therapies to overcome glioblastoma's biological barriers. Agents targeting tumor metabolism, immunotherapies, and oncolytic viruses are being investigated.
Researchers at the University of Gothenburg have identified a previously unknown protein, MSEP, that helps cells divide correctly by maintaining the cellular machinery that pulls chromosomes apart. The protein is encoded by an RNA molecule, ARHGEF17-AS1, which also has a function in cell division.
The documentary series 'Beyond the Brain' has been recognized for its scientific approach and rigorous examination of human consciousness, featuring over 50 researchers and experts from international institutions. The series has gained international recognition for its ability to address complex topics without oversimplifying them.
A study found that people evaluate others' non-cooperative behavior more based on their personal experience, even if the person has a bad reputation. In contrast, cooperative behavior is generally evaluated positively regardless of reputation or personal experience. The study suggests that people use a combination of reputation and per...
A study by Penn State researchers found that people who aged faster during midlife were more likely to experience memory lapses a decade later. The study, which analyzed data from 232 individuals, found that those who were aging rapidly were 18% more likely to experience a prospective memory lapse on any given day.
The Momentum conference brings together European cancer research leaders to discuss ways to accelerate the adoption of new cancer research advances and strengthen cross-border collaboration. The event aims to shorten the path from scientific discovery to clinical practice, ultimately benefiting patients sooner.
The DFG is establishing nine new Research Units, receiving €40 million in funding, and extending six existing units and one Centre for Advanced Studies. These initiatives focus on pressing issues in research, such as wetland conservation, media practices of contradiction, and transformative climate law.
Researchers used cryo-electron tomography to visualize the interactions between different cellular systems in bacterial cells, revealing new complexes that connect transcription and translation. This study provides a new way to study cellular 'cities' and explores molecular 'communities' rather than molecules in isolation, with potenti...
Researchers have developed a light-powered filter that maintains 99% filtration efficiency for a month and 95% for two months. The filter uses a coating that responds to light and heat, generating a continuous surface charge, making it reusable and self-cleaning.
The US will face a shortage of nearly 28,000 surgeons by 2038, with the greatest shortfalls in vascular surgery, ophthalmology, thoracic surgery, and plastic surgery. Rural areas are projected to have even worse gaps in the workforce, leading to longer waits for procedures and increased travel distances for medical care.
A retrospective cohort study of 50,802 patients with metastatic colorectal cancer found that younger patients (aged 45 and younger) had longer median disease-specific survival and a higher rate of 10-year survival compared to older patients. Younger patients were also more likely to have tumors in the left-sided colon and rectum, and a...
A digital therapeutic intervention CT-155 has shown promising results in improving motivation and pleasure negative symptoms of schizophrenia with a small-to-moderate effect size comparable to psychosocial interventions and pharmacologic treatment. CT-155 is a scalable and accessible option for improving schizophrenia negative symptoms.
Researchers found substitution effects between obesity-labeled and diabetes-labeled GLP-1 receptor agonists, which vary by state coverage policies. The study suggests that these effects could impact coverage decisions for obesity treatment in Medicaid.
A matched cohort study of over 30,000 patients found that appendectomy was associated with a 58% lower relative risk of colorectal cancer diagnosis. The exact mechanisms behind this association are unknown, but may be related to earlier detection of an underlying cancer and removal of a source of inflammation.
Patients undergoing major surgery are at a higher risk of suboptimal recovery in urban heat islands, with Black patients and those in socially vulnerable communities hit hardest. Researchers recommend incorporating questions about home cooling and hydration into discharge planning to mitigate this risk.
Researchers developed an AI model that accurately predicted pancreatic cancer risk three years before diagnosis, using a patient's comprehensive health history and routine laboratory tests. The model achieved high accuracy in distinguishing between at-risk and low-risk individuals, with an AUROC of 0.853.
E-scooter trauma admissions increased 92% from 2021 to 2023, with young riders sustaining more severe injuries. Helmet use was documented in only 12% of cases, and nearly two-thirds of injured riders under 16 sustained major injuries. Researchers call for increased caution and awareness among e-scooter riders, particularly children.
Underweight patients face a significantly higher risk of death after emergency general surgery, with a 92% increased odds compared to normal-weight patients. Those who are both underweight and frail have the worst clinical outcomes, including longer hospital stays and higher readmission rates.
Death rates from treatable emergency surgeries, such as appendicitis and hernias, rose 50% between 1999 and 2020 in the US, with rural communities experiencing a significantly higher increase. The study found that these conditions are rarely fatal when treated promptly, but more working-age adults are dying from them than in the past.
A national study of 20,000 men with prostate cancer found that surgery led to higher rates of urinary incontinence and erectile dysfunction, while radiation was associated with urinary complications and higher all-cause mortality. Researchers emphasized that both treatments have long-term consequences and that risks and benefits should...
Researchers highlight the importance of human moderation and algorithmic misinformation tagging in online patient support communities and online research. Mobile apps and patient simulator robots also play a crucial role in digitizing health records and training rural clinicians for rare emergencies.
JMIR Publications earned a spot on the 2026 Report on Business magazine ranking of Canada's Top Growing Companies, driven by the value it delivers to the scientific community. The company's sustained growth is attributed to its open science work, innovative practices, and global network of talented staff and authors.
Researchers used aircraft-mounted sensors to map chemical and structural differences in forest canopies across Peru, comparing them to over 1,300 bird species. The study found that forest type influences bird traits, such as body size and reproductive strategies, and prioritizes conservation efforts based on these differences.
Rapid economic growth in India has led to a significant increase in coal-fired power generation, resulting in worsening outdoor air pollution and a sharp rise in urban air-pollution-related deaths. The study found that a 1% increase in GDP per capita was associated with a 1.14% increase in electricity demand.
Researchers at Baylor College of Medicine discovered that stroke promotes glioma growth and tumor microenvironment changes, linking brain injury to malignant brain tumors. The study found that stroke triggers the emergence of tumor-associated astrocytes with reduced calcium activity, which suppresses glioma progression.
In vivo CAR-T therapy reduces manufacturing time and cost, enabling more accessible cancer immunotherapy. The strategy also enables superior self-renewal capacity and anti-tumor persistence.
Researchers found that stroke promotes glioma growth and tumor microenvironment remodeling, linking brain injury to malignant brain tumors. The study identified distinct populations of brain cells, including tumor-associated astrocytes, that contribute to the development of glioma.
Group 2 innate lymphoid cells (ILC2s) form tight anatomical associations with sensory, autonomic, and enteric nerve fibers, receiving neural regulation through activating and inhibitory pathways. ILC2s also secrete cytokines that can act back on neurons, forming positive feedback loops that modulate allergic and anti-infective immunity.
A 9-year study of hybrid fish populations shows rapid elimination of foreign genomic regions and maintenance of species boundaries despite extensive hybridization. Key findings include the decline of hybrid genomic regions and the role of reproductive barriers in maintaining species boundaries.
A new tool allows for genome-wide mutagenesis of bacteriophages, enabling researchers to identify essential and non-essential genes for phage survival. This method enables rapid engineering of phage genomes to improve therapeutic potential, particularly for tackling biofilms and bacterial infections.
A new approach called mkcheck2 has been developed to improve build dependency verification efficiency and accuracy. It leverages eBPF and incremental analysis to significantly reduce verification time, making continuous integration practical in large-scale projects.
Researchers at Chonnam National University discovered a century-old solvent, dichloromethane, can efficiently synthesize amide bonds. The breakthrough method enables scalable and cost-effective amide synthesis, reducing waste and using benign byproducts.