Researchers found that higher eye-blink rates in 3-6 year-olds are associated with improved cognitive flexibility and activation in the right dorsolateral prefrontal cortex. The study suggests that spontaneous eye-blink rate could be a non-invasive indicator for tracking executive function and brain development in early childhood.
Researchers found that PGK1 restricts viral replication by targeting a host chaperone required by multiple viruses, such as IAV, SeV, VSV, and HSV-1. This study expands the biological functions of a classic metabolic enzyme and reveals a link between cellular metabolism and antiviral defense.
Nottingham engineers have created a novel solid-state 'rotary' speaker that manipulates sound waves to produce a new sound effect paradigm. This method falls between electronic and mechanical effects, offering a more organic and deep sound experience.
Binghamton University professor Mohammad Younis leads a project to develop an ultrasensitive gas detection MEMS device with autonomous actuation to detect thermal runaway in lithium-ion batteries. The device features a vibrating wire and thermal conductivity principle, and can be self-contained and act autonomously
The robotic lab can autonomously assemble and fine-tune optics experiments, reducing manual setup time from days or months to minutes. This could enable scientists to focus on theoretical work and accelerate innovation in fields like quantum technologies and renewable energy.
Researchers at the University of Bristol have developed a new AI method inspired by the game of 20 Questions, which reduces training costs and complexity by combining simple yes/no questions. This approach can perform complex classification tasks at a lower computational cost, making it more suitable for real-world use, particularly in...
The summit explores the intersection of AI, eye care, and public health, with a focus on artificial intelligence, oculomics, population health, and myopia management. The event brings together leaders from healthcare, technology, and optometry to discuss innovative approaches to improve eye health and expand access to care.
A new research project, led by Lea Elsässer, investigates the role of class backgrounds in shaping political representation and decision-making in parliaments. The study aims to understand how different educational and occupational trajectories influence opportunities to access political power and legislative behavior.
The WISE Program pairs Wayne State students with Black older adults for 10-week initiatives that promote digital literacy, social connection, and meaningful relationships across generations. Students and older adults participate in guided life-story activities and work one-on-one to develop practical digital skills.
A Rutgers-led study of over 414,000 births in New Jersey found a substantially higher risk of infant mortality among infants born to mothers with depressive symptoms. Infants born to mothers with depressive symptoms had nearly three times the risk of death before the age of 1 compared to their counterparts.
Researchers used 3D imaging to explore cuprate superconductors, finding a patchwork of different crystal structures throughout their bulk, with boundaries hundreds of times wider than expected. This discovery may explain why some materials perform better than others and requires reinterpretation of existing bulk measurements.
Researchers have identified the most common features of TRND, including speech delay, autism, and vision problems, and found a possible link to type 2 diabetes. The study aims to improve recognition and diagnosis of the condition and accelerate future research.
Researchers uncovered a universal rule governing the launching of jets by black holes, which are fired at the same critical juncture in their feeding cycles. This discovery has significant implications for understanding the evolution of host galaxies and allows for more efficient use of astronomical instruments.
A recent study found that one-third of older adults with cognitive disorders are taking prescription drugs that could harm them, increasing risk of premature death and poor mental health. However, exposure to these drugs decreased significantly between 2011 and 2022, with a 11-year decline in inappropriate medication use
Researchers analyzed genomic data from 1.1 million people and identified 125 genetic susceptibility loci linked to psoriasis. They also pinpointed 50 promising therapeutic target genes through single-cell transcriptomic analysis, paving the way for personalized immune-modulating treatments.
Old-growth forests in Northern Europe are vital for biodiversity, climate regulation, and cultural heritage, but face threats from logging and habitat destruction. A new review provides science-based indicators for identifying and protecting these ecosystems, emphasizing the importance of considering the forest as a whole.
Researchers developed a chirality-engineered ruthenium nanozyme that protects against chemotherapy-induced cardiotoxicity by modulating the gut-heart axis. The nanozyme restored gut microbial homeostasis and host metabolism, reducing oxidative stress and inflammation, while maintaining anticancer efficacy.
Researchers mapped the Challenger Deep using the EM124 multibeam echosounder, finding a preferred estimate of 10,927 m, which highlights the importance of sound-speed models, vessel speed, and survey conditions. The study's dataset is publicly available, allowing for further validation and comparison with other observations.
Sea surface temperature biases affect North Pacific westerly jet positioning in climate models, according to a new study. The study found that westerly jet shifts southward when climate models simulate warmer sea surface temperatures compared to observed temperatures.
Researchers used photons and electrons to create hollow gold nanoboxes, differing in material properties, and demonstrated that beam observation affects chemical reactions.
A new gel electrolyte helps zinc iodine batteries operate in a wide temperature range, from -40 to 90°C. The electrolyte design regulates water activity and stabilizes both electrodes, improving battery durability and performance.
Researchers investigate tetragonal zirconia nanoparticles under hydrostatic and anisotropic pressure, revealing transformations in crystal structure that could be used to detect pressure anisotropy. This approach has potential applications in various fields, including food processing, medicine, and materials research.
Researchers have developed compact diamond magnetometers that measure biomagnetic signals with high precision, opening new avenues for medical diagnostics. The technology offers improved paths towards early detection of conditions such as myocarditis and epilepsy.
The study reveals that sari-sari stores serve as community pharmacies, providing common medicines and adapting to community needs. Despite being illegal, the researchers argue for policies that account for economic and geographical barriers, recognizing the value of these stores in the healthcare system.
The Institute of Science and Technology Austria (ISTA) is now accepting applications for its 2027 Journalist in Residence program. The program invites experienced science and technology journalists to spend three to six months on its international campus, where they can meet leading scientists, experience curiosity-driven basic researc...
Super-resolution microscopy is transforming the field of molecular imaging by enabling researchers to measure molecular organization and behavior with increased accuracy. Advances in artificial intelligence, fluorescent probes, and image analysis are making nanoscale imaging faster, deeper, and more reliable.
Francisco Rivadulla, a researcher at the Center for Research in Biological Chemistry and Molecular Materials (CiQUS), has been awarded the Antonio Casares Rodríguez Medal for his groundbreaking work in solid-state chemistry and condensed-matter physics. The recognition highlights the centre's contribution to advancing chemistry and tra...
Researchers at Helmholtz-Zentrum Dresden-Rossendorf successfully produce high-purity, ultra-small nanodiamonds using laser compression, offering a scalable and sustainable alternative to conventional methods. The diamonds can be used in various applications, including medicine, energy technology, and catalysis.
Researchers at the University of Warwick have identified TRPM2 as a direct pain transducer that amplifies chronic pain signals. Blocking TRPM2 with a drug injected into the joint completely reversed arthritis pain in mice, providing a promising new approach to treating chronic pain more effectively.
Astronomers have long suspected black holes follow the same physics regardless of size, but proving it was difficult due to supermassive black hole evolution. WA scientist Dr Adelle Goodwin helped crack the code by studying tidal disruption events, finding two distinct jet-launching phases
A Northwestern University study reveals that people with congenital ichthyosis have higher rates of food allergies, asthma, and hay fever than the general U.S. population. The study's findings may advance scientific understanding of how the skin's protective barrier plays a role in allergic disease.
Scientists create gradient magnetic field-controllable SERS substrate, enabling zone-specific Raman signal enhancement and improved detection performance. The NdFeB substrate regulates particle distribution, forming effective nanogaps and maximizing SERS enhancement efficiency.
Researchers uncover molecular mechanism by which Plasmodium falciparum increases gametocyte production in response to stress, enabling rapid transmission to mosquitoes. The study identifies key regulators, including GDV1 and AP2-HS, that trigger a regulatory feedback loop to control gametocyte production.
Researchers developed a high-entropy sulfide catalyst that preserves its structure and suppresses atomic migration, enabling high sulfur utilization and conversion efficiency. The study proposes a failure-mechanism-guided approach to catalyst design, pointing to unresolved questions in all-solid-state sulfur chemistry.
The cGAS-STING pathway connects cellular aging to brain inflammation, with self-DNA accumulating in the cytoplasm and triggering chronic inflammation. Mitochondrial DNA plays a key role in this process, linking metabolic dysfunction to glial activation and neuronal damage.
The new NCCN Guidelines for Patients with Cancer explain the importance of assessments to tailor cancer care to every person, regardless of age. The guidelines stress the need for support and validation for older adults, who face unique issues such as memory function and treatment interactions with other medications and conditions.
Researchers surveyed the ocean's medicine cabinet, discovering cancer-fighting alkaloids and antiviral compounds in coral reefs and deep-sea habitats. Sustainable sourcing and conservation are key to unlocking these compounds' full potential.
Research found that the brains of deaf individuals redistribute neural resources to prioritize peripheral vision, enabling them to detect movement and events outside their central field of view. This adaptation allows deaf adults to excel at monitoring their surroundings, potentially providing an advantage in detecting danger.
Researchers at the University of Stuttgart have developed a new technique that allows for simultaneous excitation and detection in MRI, reducing dead time and enabling precise imaging of rapidly decaying signals. This method has potential applications in medical imaging, materials research, and safety inspections, and could lead to new...
A recent study by 80 researchers from 16 countries identified significant gaps in knowledge about Antarctic ice thickness and bed topography, leading to inaccurate ice sheet models. The study emphasizes the importance of international coordination and comprehensive data collection to improve sea level projections.
A new physics-inspired model, PI-TGNet, can generate regional thunderstorm-gust identification maps every 10 minutes with high accuracy. The model integrates ground-based weather stations, weather radar, and satellite observations to learn characteristic wind-speed changes before thunderstorm gusts.
Researchers discovered that gut bacteria produce vaccenic acid, a substance that activates the LRH-1 receptor, improving metabolic health and reducing inflammation. The study highlights the crucial role of the gut microbiome in regulating physiological processes and overall metabolism.
A new AI-powered test, IICM+, has been developed to predict breast cancer recurrence risk more accurately than the widely used 21-gene Recurrence Score. IICM+ uses clinical, molecular, and histopathology data to provide reliable prognostic information, distinguishing between patients at different risks of recurrence.
The American Heart Association scientific statement highlights the need for sex-specific research analyses and tailored care to improve women's kidney health. Women are more likely to experience delayed diagnosis and treatment due to differences in biology and social factors.
Research challenges traditional views of cognitive decline in aging, highlighting the brain's natural shift towards prioritizing wisdom and understanding over details. This adaptation enables older adults to effectively share accumulated knowledge and social relationships with younger generations.
A new commentary calls for consistent evaluation of potential links between COVID-19, vaccination, and cancer, highlighting potential associations and biological mechanisms. The author argues that similar mechanisms reported in connection with COVID-19 vaccination warrant consideration and further study.
NJIT professor Simone Marras invents Jexpresso software to predict hurricanes and tsunamis more accurately and faster than ever. The new technique uses artificial intelligence on a simulation of a quantum reservoir computer to manipulate weather data for pattern discovery, potentially saving lives and protecting property.
Researchers at Lund University found that heavy menstrual bleeding, skipping meals, and daily nicotine use are linked to higher levels of self-reported tiredness in teenage girls. Iron deficiency was not found to be a cause of fatigue in the study.
Inailico Medicine has developed an open AI toolkit, including LongevityBench, Longevity-LLMs, and LongevityClaw, to accelerate research and therapeutic development in aging and longevity. The toolkit aims to help scientists identify and develop the next generation of longevity interventions.
Gustave Roussy is ranked Europe's leading cancer center and third best worldwide, reflecting its excellence in patient care and innovation. The Institute's unique model integrates care, research, and education to give patients faster access to cancer treatments.
A molecular bridge connects two small GTPase pathways in plants, enabling communication between RAB5 and ROP7 pathways. This connection plays a crucial role in pollen development, and disrupting it affects plant reproduction. The study reveals a new insight into how small GTPase systems are integrated in plants.
A Texas A&M University study found that employees who consumed more negatively perceived political information experienced higher anxiety and lower work engagement. Conversely, consuming positive political information was associated with greater hope, stronger engagement, and higher helping behavior towards co-workers.
A new study from Dana-Farber Cancer Institute reveals that 'cold' tumors can hide molecular flags from T cells, making them harder to attack. The researchers suggest that changing what the cancer displays on its surface could help the immune system recognize the tumor, offering a new route to turn 'cold' tumors 'hot'.
A new method involving local anesthesia in the uterus reduces pain during IUD insertion by 15 units, increasing the proportion of women who find the procedure tolerable from 91.4% to 98.3%.
An underground experiment has tested a theory linking gravity to quantum decoherence, ruling out a pioneering model. The Gran Sasso National Laboratory provided an ideal environment to detect subtle fluctuations predicted by the theory, but no signal was detected, shedding light on the interplay between gravity and quantum mechanics.
Researchers have identified candidate treatment targets for high-grade glioma in children, adolescents, and young adults, with distinct tumor biology and outcomes across patient groups. The study found that kinases, including CDK8, ATM, and ATR, may suppress oxidative phosphorylation and are potential targets for therapy.
A recent study published in iScience found that AI-powered machines have difficulty recognizing objects from their overall shapes when aspects of an image are distorted. Humans, on the other hand, are able to leverage the global shape cue for visual object recognition, a skill that current AI models do not replicate.
Researchers identified inflammatory pathways that drive kidney damage in diabetic kidney disease, suggesting a potential new approach for protecting the kidneys. Drug treatments targeting dysregulated inflammatory pathways protected kidney organoids from damage, even when exposed to high sugar levels.
A multicenter randomized clinical trial of 370 nulliparous individuals found that intrauterine mepivacaine instillation significantly reduced pain and improved tolerability during IUD placement compared to placebo saline. The study supports mepivacaine instillation as a simple approach to improve the IUD placement experience.
Scientists at Hackensack Meridian Center for Discovery and Innovation developed a new BCG vaccine strategy that significantly reduces tuberculosis relapse rates. The study found that combining BCG vaccination with immunotherapy lowered relapse rates by 58% compared to the vaccine alone.